Elizabeth O Ofili
Affiliation: Morehouse School of Medicine
- Antihypertensive and metabolic effects of Angiotensin receptor blocker/diuretic combination therapy in obese, hypertensive African American and white patientsElizabeth O Ofili
Department of Medicine, Clinical Research Center, Morehouse School of Medicine, Atlanta, GA 30310 1495, USA
Am J Ther 20:2-12. 2013..In both racial/ethnic subgroups, the addition of valsartan to hydrochlorothiazide reduced the negative metabolic effects associated with thiazide therapy...
- Efficacy and safety of fixed combinations of irbesartan/hydrochlorothiazide in hypertensive women: the inclusive trialElizabeth O Ofili
Morehouse School of Medicine, Atlanta, Georgia 30310, USA
J Womens Health (Larchmt) 17:931-8. 2008....
- Irbesartan/HCTZ fixed combinations in patients of different racial/ethnic groups with uncontrolled systolic blood pressure on monotherapyElizabeth O Ofili
Clinical Research Center, Morehouse School of Medicine, Atlanta, GA 30310, USA
J Natl Med Assoc 98:618-26. 2006..In conclusion, irbesartan/HCTZ treatment provided SBP/DBP goal attainment in approximately two-thirds of Caucasian, African-American and Hispanic/Latino patients with SBP uncontrolled on antihypertensive monotherapy...
- Dispelling the myth of "aggressive" antihypertensive therapyElizabeth O Ofili
Morehouse School of Medicine, Atlanta, GA 30310, USA
J Clin Hypertens (Greenwich) 8:4-11. 2006..Such formulations are also cost-effective. Thus, reducing blood pressure using multiple drugs as fixed-dose combinations is a strategy that recognizes the multiple pathophysiologic changes that lead to hypertension...
- The Community Physicians' Network (CPN): an academic-community partnership to eliminate healthcare disparitiesElizabeth Ofili
Clinical Research Center, Department of Medicine, Morehouse School of Medicine, Atlanta, GA 30310, USA
Ethn Dis 15:S5-124-7. 2005..The Morehouse School of Medicine Community Physicians' Network (CPN) was established to address disparities in health care by focusing on provider-specific strategies...
- Targeting healthcare disparities: an integrated model to improve treatment rates of dyslipidemia in African American patientsElizabeth Ofili
The Clinical Research Center and the Department of Medicine, Morehouse School of Medicine, Atlanta, GA 30310, USA
Curr Atheroscler Rep 7:249-50. 2005
- Moderate versus intensive treatment of hypertension using amlodipine/valsartan and with the addition of hydrochlorothiazide for patients uncontrolled on angiotensin receptor blocker monotherapy: results in racial/ethnic subgroupsElizabeth O Ofili
Morehouse School of Medicine, Atlanta, Georgia, USA
J Am Soc Hypertens 5:249-58. 2011..0 mm Hg (moderate), across racial/ethnic subgroups. Both regimens were well tolerated. Amlodipine/valsartan/HCTZ combination therapy was efficacious across racial/ethnic subgroups. Maximal efficacy was obtained with intensive treatment...
- Cardiovascular risk factor control in communities--update from the ASH Carolinas-Georgia Chapter, the Hypertension Initiative, and the Community Physicians' NetworkBrent M Egan
Department of Medicine, Medical University of South Carolina, 135 Rutledge Avenue, Charleston, SC 29425, USA
J Clin Hypertens (Greenwich) 8:879-86. 2006..Evidence suggests that this collaboration is facilitating application of evidence-based medicine and risk factor control...
- Relation of endothelial nitric oxide synthase gene to plasma nitric oxide level, endothelial function, and blood pressure in African AmericansRongling Li
Department of Medicine, Clinical Research Center, Atlanta, Georgia, USA
Am J Hypertens 17:560-7. 2004..The role of eNOS gene polymorphisms on plasma nitrite or nitrate (NOx) level, endothelial function, and blood pressure (BP) remains unclear...
- Ultralate referral and presentation for renal replacement therapy: socioeconomic implicationsChamberlain I Obialo
Renal Section, Clinical Research Center, Morehouse School of Medicine, Atlanta, GA 30310, USA
Am J Kidney Dis 46:881-6. 2005..This study examines the role of lifestyle and socioeconomic status on referral pattern...
- Moderate versus intensive treatment of hypertension with amlodipine/valsartan for patients uncontrolled on angiotensin receptor blocker monotherapySuzanne Oparil
Department of Medicine Cardiovascular, University of Alabama at Birmingham, Birmingham, Alabama 35294 1150, USA
J Hypertens 29:161-70. 2011..We investigated whether initiating intensive treatment with combination amlodipine/valsartan was superior to moderate treatment with amlodipine/valsartan in patients previously uncontrolled on ARB monotherapy...
- Management of high blood pressure in African Americans: consensus statement of the Hypertension in African Americans Working Group of the International Society on Hypertension in BlacksJanice G Douglas
Case Western Reserve University, Department of Medicine, Room W 165, 10900 Euclid Ave, Cleveland, Ohio 44106, USA
Arch Intern Med 163:525-41. 2003
- The 894T allele of endothelial nitric oxide synthase gene is related to left ventricular mass in African Americans with high-normal blood pressureRigobert Lapu-Bula
Division of Cardiology, Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 30310, USA
J Natl Med Assoc 97:197-205. 2005....
- The prevalence of cognitive impairment among African-American patients with congestive heart failureAbimbola Akomolafe
Department of Medicine, Clinical Research Center, Morehouse School of Medicine, Atlanta, GA 30310, USA
J Natl Med Assoc 97:689-94. 2005..This study indicates that cognitive impairment is relatively prevalent among African Americans with CHF, but lower than previously reported among Caucasians with CHF...
- Morehouse Community Physicians Network (CPN) hypertension registry: patterns of care and opportunities for targeted medical educationPriscilla Igho-Pemu
Division of General Internal Medicine, The Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA
Ethn Dis 15:S5-120-3. 2005..We examined the registry to identify patterns of care and opportunities for provider-focused interventions to improve patient outcomes...
- Comparative frequency of angiographic coronary artery disease in African Americans and HispanicsAnekwe E Onwuanyi
Section of Cardiology, Department of Medicine, Morehouse School of Medicine, 720 Westview Drive, Atlanta, GA 30310 1495, USA
Ethn Dis 16:58-63. 2006..Whereas a large body of clinical data compares African Americans and Whites or Hispanics and Whites with regard to coronary artery disease (CAD), limited data are available for such comparison between African Americans and Hispanics...
- Hyperkalemia in congestive heart failure patients aged 63 to 85 years with subclinical renal diseaseChamberlain I Obialo
Renal Section, Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia 30310, USA
Am J Cardiol 90:663-5. 2002
- Comparative analysis of the efficacy of continuous glucose monitoring and self-monitoring of blood glucose in type 1 diabetes mellitusBaraka Floyd
Department of Medicine, Clinical Research Center, Morehouse School of Medicine, Atlanta, Georgia, USA
J Diabetes Sci Technol 6:1094-102. 2012..It is not clear, however, if CGM provides further efficacy and safety benefits beyond SMBG in the management of T1DM...
- Ability of troponin T to predict angiographic coronary artery disease in patients with chronic kidney diseaseChamberlain I Obialo
Department of Medicine, Morehouse School of Medicine, Grady Memorial Hospital, 720 West View Drive SW, Atlanta, GA 30310, USA
Am J Cardiol 94:834-6. 2004..Troponin T levels significantly correlated with CAs in patients with normal kidney function (r = 0.4, p = 0.005) but not in ESRD and CKD patients (r = 0.2, p = NS, respectively)...
- Early alterations of the immune transcriptome in cultured progenitor cells from obese African-American womenPRISCILLA E PEMU
Clinical Research Center, Morehouse School of Medicine, Atlanta, GA, USA
Obesity (Silver Spring) 20:1481-90. 2012..Clinically, this may translate into a lengthier period of immune dysregulation in obese subjects exposing them to greater risks of infection and other morbidities...
- Ethnic differences in electrocardiographic criteria for left ventricular hypertrophy: the LIFE study. Losartan Intervention For EndpointPeter M Okin
Department of Medicine, Weill Medical College of Cornell University, New York, New York 10021, USA
Am J Hypertens 15:663-71. 2002..However, the high mortality associated with LVH in African American patients makes more accurate ECG detection of LVH in these patients a clinical priority...
- From hypertension to heart failure: role of nitric oxide-mediated endothelial dysfunction and emerging insights from myocardial contrast echocardiographyRigobert Lapu-Bula
Division of Cardiology and the Clinical Research Center, Morehouse School of Medicine, Atlanta, Georgia 30310, USA
Am J Cardiol 99:7D-14D. 2007..These data support further evaluation of NO mediators as potential targets for novel therapies in hypertensive heart disease...
- Diastolic heart failure: the forgotten manifestation of hypertensive heart diseaseRigobert Lapu-Bula
Division of Cardiology, Department of Medicine, Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 30310, USA
Curr Hypertens Rep 6:164-70. 2004..Ongoing clinical trials are testing new strategies for treatment of diastolic HF...
- Hypertension in women: part IPriscilla Igho Pemu
Department of Medicine and the Clinical Research Center, Atlanta, GA, USA
J Clin Hypertens (Greenwich) 10:406-10. 2008..The current evidence therefore indicates that sex should not play a role in decisions about whether to treat hypertension or about the choice of agents...
- Hypertension in women--part IIPriscilla Igho Pemu
Department of Medicine and the Clinical Research Center, Morehouse School of Medicine, Atlanta, GA 30310, USA
J Clin Hypertens (Greenwich) 10:497-500. 2008..This section focuses on the treatment of hypertension in special circumstances and special populations: pregnancy, preeclampsia, and lactation; hypertension in black women; and hypertension in the elderly...
- Models of interinstitutional partnerships between research intensive universities and minority serving institutions (MSI) across the Clinical Translational Science Award (CTSA) consortiumElizabeth O Ofili
Atlanta Clinical Translational Science Institute ACTSI, RCMI Center of Excellence for Clinical and Translational Research, and Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia, USA
Clin Transl Sci 6:435-43. 2013....
- Socio-demographic psychosocial and clinical characteristics of participants in e-HealthyStrides©: an interactive ehealth program to improve diabetes self-management skillsPRISCILLA E PEMU
Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 30310, USA
J Health Care Poor Underserved 22:146-64. 2011..Requestors were more obese with worse A1C than others. Chronic care delivery scored average with high scores for counseling and problem solving but low scores for care coordination and follow up...
- Early and sustained benefit on event-free survival and heart failure hospitalization from fixed-dose combination of isosorbide dinitrate/hydralazine: consistency across subgroups in the African-American Heart Failure TrialAnne L Taylor
Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA
Circulation 115:1747-53. 2007....
- Association of distinct variants in SORL1 with cerebrovascular and neurodegenerative changes related to Alzheimer diseaseKaren T Cuenco
Genetics Program, Department of Medicine, Room L320, Boston University School of Medicine, 715 Albany St, Boston, MA 02118, USA
Arch Neurol 65:1640-8. 2008....
- New York Heart Association functional class predicts exercise parameters in the current eraStuart D Russell
Department of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
Am Heart J 158:S24-30. 2009..Using baseline data from the HF-ACTION (Heart Failure and A Controlled Trial Investigating Outcomes of Exercise TraiNing) study, we examined this relationship...
- Outcomes by gender in the African-American Heart Failure TrialAnne L Taylor
Department of Medicine, University of Minnesota, Minneapolis, Minnesota 55455, USA
J Am Coll Cardiol 48:2263-7. 2006..We therefore compared outcomes by gender and treatment...
- Efficacy and safety of fixed combinations of irbesartan/hydrochlorothiazide in older vs younger patients with hypertension uncontrolled with monotherapyWilliam C Cushman
University of Tennessee College of Medicine and Veterans Affairs Medical Center, Memphis, TN, USA
Am J Geriatr Cardiol 17:27-36. 2008..Irbesartan/HCTZ combination therapy allowed SBP goal attainment in 73% of patients aged 65 years or older whose hypertension was previously uncontrolled with antihypertensive monotherapy...
- Antihypertensive efficacy of Irbesartan/HCTZ in men and women with the metabolic syndrome and type 2 diabetesJames R Sowers
University of Missouri Columbia and Harry S Truman VA Medical Center, 65212, USA
J Clin Hypertens (Greenwich) 8:470-80. 2006..Irbesartan/HCTZ fixed combinations achieved SBP goals in over half of the T2DM patients and nearly three quarters of patients with the metabolic syndrome, with SBP uncontrolled on antihypertensive monotherapy...
- The efficacy and safety of low- and high-dose fixed combinations of irbesartan/hydrochlorothiazide in patients with uncontrolled systolic blood pressure on monotherapy: the INCLUSIVE trialJoel M Neutel
Orange County Research Center, Tustin, CA 92780, USA
J Clin Hypertens (Greenwich) 7:578-86. 2005..Treatments were well tolerated. This irbesartan/HCTZ treatment regimen achieved SBP goals in more than 75% of patients uncontrolled on monotherapy...
- Addressing health disparities through multi-institutional, multidisciplinary collaboratoriesErik S Fleming
Research Centers in Minority Institutions Translational Research Network, Charles R Drew University of Medicine and Science, Los Angeles, California 90062, USA
Ethn Dis 18:S2-161-7. 2008....
- Clinical assessment of the risk for sudden cardiac death in patients with sickle cell anemiaJohn M Fontaine
Drexe University College of Medicine, Philadelphia, PA 19102, USA
J Natl Med Assoc 100:360-8. 2008..An abnormal microvolt T-wave alternans (TWA) test is also a predictor of sudden cardiac death risk, but it has not been applied to this patient population...
- Working group 3: How to encourage more minorities to choose a career in cardiologyCharles K Francis
J Am Coll Cardiol 44:241-5. 2004