Elizabeth O Ofili

Summary

Affiliation: Morehouse School of Medicine
Country: USA

Publications

  1. pmc Antihypertensive and metabolic effects of Angiotensin receptor blocker/diuretic combination therapy in obese, hypertensive African American and white patients
    Elizabeth O Ofili
    Department of Medicine, Clinical Research Center, Morehouse School of Medicine, Atlanta, GA 30310 1495, USA
    Am J Ther 20:2-12. 2013
  2. pmc Efficacy and safety of fixed combinations of irbesartan/hydrochlorothiazide in hypertensive women: the inclusive trial
    Elizabeth O Ofili
    Morehouse School of Medicine, Atlanta, Georgia 30310, USA
    J Womens Health (Larchmt) 17:931-8. 2008
  3. pmc Irbesartan/HCTZ fixed combinations in patients of different racial/ethnic groups with uncontrolled systolic blood pressure on monotherapy
    Elizabeth O Ofili
    Clinical Research Center, Morehouse School of Medicine, Atlanta, GA 30310, USA
    J Natl Med Assoc 98:618-26. 2006
  4. ncbi request reprint Dispelling the myth of "aggressive" antihypertensive therapy
    Elizabeth O Ofili
    Morehouse School of Medicine, Atlanta, GA 30310, USA
    J Clin Hypertens (Greenwich) 8:4-11. 2006
  5. ncbi request reprint The Community Physicians' Network (CPN): an academic-community partnership to eliminate healthcare disparities
    Elizabeth Ofili
    Clinical Research Center, Department of Medicine, Morehouse School of Medicine, Atlanta, GA 30310, USA
    Ethn Dis 15:S5-124-7. 2005
  6. ncbi request reprint Targeting healthcare disparities: an integrated model to improve treatment rates of dyslipidemia in African American patients
    Elizabeth Ofili
    The Clinical Research Center and the Department of Medicine, Morehouse School of Medicine, Atlanta, GA 30310, USA
    Curr Atheroscler Rep 7:249-50. 2005
  7. pmc Moderate versus intensive treatment of hypertension using amlodipine/valsartan and with the addition of hydrochlorothiazide for patients uncontrolled on angiotensin receptor blocker monotherapy: results in racial/ethnic subgroups
    Elizabeth O Ofili
    Morehouse School of Medicine, Atlanta, Georgia, USA
    J Am Soc Hypertens 5:249-58. 2011
  8. ncbi request reprint Cardiovascular risk factor control in communities--update from the ASH Carolinas-Georgia Chapter, the Hypertension Initiative, and the Community Physicians' Network
    Brent M Egan
    Department of Medicine, Medical University of South Carolina, 135 Rutledge Avenue, Charleston, SC 29425, USA
    J Clin Hypertens (Greenwich) 8:879-86. 2006
  9. ncbi request reprint Relation of endothelial nitric oxide synthase gene to plasma nitric oxide level, endothelial function, and blood pressure in African Americans
    Rongling Li
    Department of Medicine, Clinical Research Center, Atlanta, Georgia, USA
    Am J Hypertens 17:560-7. 2004
  10. ncbi request reprint Ultralate referral and presentation for renal replacement therapy: socioeconomic implications
    Chamberlain I Obialo
    Renal Section, Clinical Research Center, Morehouse School of Medicine, Atlanta, GA 30310, USA
    Am J Kidney Dis 46:881-6. 2005

Detail Information

Publications37

  1. pmc Antihypertensive and metabolic effects of Angiotensin receptor blocker/diuretic combination therapy in obese, hypertensive African American and white patients
    Elizabeth O Ofili
    Department of Medicine, Clinical Research Center, Morehouse School of Medicine, Atlanta, GA 30310 1495, USA
    Am J Ther 20:2-12. 2013
    ..In both racial/ethnic subgroups, the addition of valsartan to hydrochlorothiazide reduced the negative metabolic effects associated with thiazide therapy...
  2. pmc Efficacy and safety of fixed combinations of irbesartan/hydrochlorothiazide in hypertensive women: the inclusive trial
    Elizabeth O Ofili
    Morehouse School of Medicine, Atlanta, Georgia 30310, USA
    J Womens Health (Larchmt) 17:931-8. 2008
    ....
  3. pmc Irbesartan/HCTZ fixed combinations in patients of different racial/ethnic groups with uncontrolled systolic blood pressure on monotherapy
    Elizabeth O Ofili
    Clinical Research Center, Morehouse School of Medicine, Atlanta, GA 30310, USA
    J Natl Med Assoc 98:618-26. 2006
    ..In conclusion, irbesartan/HCTZ treatment provided SBP/DBP goal attainment in approximately two-thirds of Caucasian, African-American and Hispanic/Latino patients with SBP uncontrolled on antihypertensive monotherapy...
  4. ncbi request reprint Dispelling the myth of "aggressive" antihypertensive therapy
    Elizabeth O Ofili
    Morehouse School of Medicine, Atlanta, GA 30310, USA
    J Clin Hypertens (Greenwich) 8:4-11. 2006
    ..Such formulations are also cost-effective. Thus, reducing blood pressure using multiple drugs as fixed-dose combinations is a strategy that recognizes the multiple pathophysiologic changes that lead to hypertension...
  5. ncbi request reprint The Community Physicians' Network (CPN): an academic-community partnership to eliminate healthcare disparities
    Elizabeth Ofili
    Clinical Research Center, Department of Medicine, Morehouse School of Medicine, Atlanta, GA 30310, USA
    Ethn Dis 15:S5-124-7. 2005
    ..The Morehouse School of Medicine Community Physicians' Network (CPN) was established to address disparities in health care by focusing on provider-specific strategies...
  6. ncbi request reprint Targeting healthcare disparities: an integrated model to improve treatment rates of dyslipidemia in African American patients
    Elizabeth Ofili
    The Clinical Research Center and the Department of Medicine, Morehouse School of Medicine, Atlanta, GA 30310, USA
    Curr Atheroscler Rep 7:249-50. 2005
  7. pmc Moderate versus intensive treatment of hypertension using amlodipine/valsartan and with the addition of hydrochlorothiazide for patients uncontrolled on angiotensin receptor blocker monotherapy: results in racial/ethnic subgroups
    Elizabeth O Ofili
    Morehouse School of Medicine, Atlanta, Georgia, USA
    J Am Soc Hypertens 5:249-58. 2011
    ..0 mm Hg (moderate), across racial/ethnic subgroups. Both regimens were well tolerated. Amlodipine/valsartan/HCTZ combination therapy was efficacious across racial/ethnic subgroups. Maximal efficacy was obtained with intensive treatment...
  8. ncbi request reprint Cardiovascular risk factor control in communities--update from the ASH Carolinas-Georgia Chapter, the Hypertension Initiative, and the Community Physicians' Network
    Brent M Egan
    Department of Medicine, Medical University of South Carolina, 135 Rutledge Avenue, Charleston, SC 29425, USA
    J Clin Hypertens (Greenwich) 8:879-86. 2006
    ..Evidence suggests that this collaboration is facilitating application of evidence-based medicine and risk factor control...
  9. ncbi request reprint Relation of endothelial nitric oxide synthase gene to plasma nitric oxide level, endothelial function, and blood pressure in African Americans
    Rongling Li
    Department of Medicine, Clinical Research Center, Atlanta, Georgia, USA
    Am J Hypertens 17:560-7. 2004
    ..The role of eNOS gene polymorphisms on plasma nitrite or nitrate (NOx) level, endothelial function, and blood pressure (BP) remains unclear...
  10. ncbi request reprint Ultralate referral and presentation for renal replacement therapy: socioeconomic implications
    Chamberlain I Obialo
    Renal Section, Clinical Research Center, Morehouse School of Medicine, Atlanta, GA 30310, USA
    Am J Kidney Dis 46:881-6. 2005
    ..This study examines the role of lifestyle and socioeconomic status on referral pattern...
  11. pmc Moderate versus intensive treatment of hypertension with amlodipine/valsartan for patients uncontrolled on angiotensin receptor blocker monotherapy
    Suzanne Oparil
    Department of Medicine Cardiovascular, University of Alabama at Birmingham, Birmingham, Alabama 35294 1150, USA
    J Hypertens 29:161-70. 2011
    ..We investigated whether initiating intensive treatment with combination amlodipine/valsartan was superior to moderate treatment with amlodipine/valsartan in patients previously uncontrolled on ARB monotherapy...
  12. ncbi request reprint Management of high blood pressure in African Americans: consensus statement of the Hypertension in African Americans Working Group of the International Society on Hypertension in Blacks
    Janice G Douglas
    Case Western Reserve University, Department of Medicine, Room W 165, 10900 Euclid Ave, Cleveland, Ohio 44106, USA
    Arch Intern Med 163:525-41. 2003
  13. pmc The 894T allele of endothelial nitric oxide synthase gene is related to left ventricular mass in African Americans with high-normal blood pressure
    Rigobert Lapu-Bula
    Division of Cardiology, Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 30310, USA
    J Natl Med Assoc 97:197-205. 2005
    ....
  14. pmc The prevalence of cognitive impairment among African-American patients with congestive heart failure
    Abimbola Akomolafe
    Department of Medicine, Clinical Research Center, Morehouse School of Medicine, Atlanta, GA 30310, USA
    J Natl Med Assoc 97:689-94. 2005
    ..This study indicates that cognitive impairment is relatively prevalent among African Americans with CHF, but lower than previously reported among Caucasians with CHF...
  15. ncbi request reprint Morehouse Community Physicians Network (CPN) hypertension registry: patterns of care and opportunities for targeted medical education
    Priscilla Igho-Pemu
    Division of General Internal Medicine, The Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA
    Ethn Dis 15:S5-120-3. 2005
    ..We examined the registry to identify patterns of care and opportunities for provider-focused interventions to improve patient outcomes...
  16. ncbi request reprint Comparative frequency of angiographic coronary artery disease in African Americans and Hispanics
    Anekwe E Onwuanyi
    Section of Cardiology, Department of Medicine, Morehouse School of Medicine, 720 Westview Drive, Atlanta, GA 30310 1495, USA
    Ethn Dis 16:58-63. 2006
    ..Whereas a large body of clinical data compares African Americans and Whites or Hispanics and Whites with regard to coronary artery disease (CAD), limited data are available for such comparison between African Americans and Hispanics...
  17. ncbi request reprint Hyperkalemia in congestive heart failure patients aged 63 to 85 years with subclinical renal disease
    Chamberlain I Obialo
    Renal Section, Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia 30310, USA
    Am J Cardiol 90:663-5. 2002
  18. pmc Comparative analysis of the efficacy of continuous glucose monitoring and self-monitoring of blood glucose in type 1 diabetes mellitus
    Baraka Floyd
    Department of Medicine, Clinical Research Center, Morehouse School of Medicine, Atlanta, Georgia, USA
    J Diabetes Sci Technol 6:1094-102. 2012
    ..It is not clear, however, if CGM provides further efficacy and safety benefits beyond SMBG in the management of T1DM...
  19. ncbi request reprint Ability of troponin T to predict angiographic coronary artery disease in patients with chronic kidney disease
    Chamberlain I Obialo
    Department of Medicine, Morehouse School of Medicine, Grady Memorial Hospital, 720 West View Drive SW, Atlanta, GA 30310, USA
    Am J Cardiol 94:834-6. 2004
    ..Troponin T levels significantly correlated with CAs in patients with normal kidney function (r = 0.4, p = 0.005) but not in ESRD and CKD patients (r = 0.2, p = NS, respectively)...
  20. pmc Early alterations of the immune transcriptome in cultured progenitor cells from obese African-American women
    PRISCILLA E PEMU
    Clinical Research Center, Morehouse School of Medicine, Atlanta, GA, USA
    Obesity (Silver Spring) 20:1481-90. 2012
    ..Clinically, this may translate into a lengthier period of immune dysregulation in obese subjects exposing them to greater risks of infection and other morbidities...
  21. ncbi request reprint Ethnic differences in electrocardiographic criteria for left ventricular hypertrophy: the LIFE study. Losartan Intervention For Endpoint
    Peter M Okin
    Department of Medicine, Weill Medical College of Cornell University, New York, New York 10021, USA
    Am J Hypertens 15:663-71. 2002
    ..However, the high mortality associated with LVH in African American patients makes more accurate ECG detection of LVH in these patients a clinical priority...
  22. ncbi request reprint From hypertension to heart failure: role of nitric oxide-mediated endothelial dysfunction and emerging insights from myocardial contrast echocardiography
    Rigobert Lapu-Bula
    Division of Cardiology and the Clinical Research Center, Morehouse School of Medicine, Atlanta, Georgia 30310, USA
    Am J Cardiol 99:7D-14D. 2007
    ..These data support further evaluation of NO mediators as potential targets for novel therapies in hypertensive heart disease...
  23. ncbi request reprint Diastolic heart failure: the forgotten manifestation of hypertensive heart disease
    Rigobert Lapu-Bula
    Division of Cardiology, Department of Medicine, Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 30310, USA
    Curr Hypertens Rep 6:164-70. 2004
    ..Ongoing clinical trials are testing new strategies for treatment of diastolic HF...
  24. pmc Hypertension in women: part I
    Priscilla Igho Pemu
    Department of Medicine and the Clinical Research Center, Atlanta, GA, USA
    J Clin Hypertens (Greenwich) 10:406-10. 2008
    ..The current evidence therefore indicates that sex should not play a role in decisions about whether to treat hypertension or about the choice of agents...
  25. pmc Hypertension in women--part II
    Priscilla Igho Pemu
    Department of Medicine and the Clinical Research Center, Morehouse School of Medicine, Atlanta, GA 30310, USA
    J Clin Hypertens (Greenwich) 10:497-500. 2008
    ..This section focuses on the treatment of hypertension in special circumstances and special populations: pregnancy, preeclampsia, and lactation; hypertension in black women; and hypertension in the elderly...
  26. pmc Models of interinstitutional partnerships between research intensive universities and minority serving institutions (MSI) across the Clinical Translational Science Award (CTSA) consortium
    Elizabeth O Ofili
    Atlanta Clinical Translational Science Institute ACTSI, RCMI Center of Excellence for Clinical and Translational Research, and Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia, USA
    Clin Transl Sci 6:435-43. 2013
    ....
  27. pmc Socio-demographic psychosocial and clinical characteristics of participants in e-HealthyStrides©: an interactive ehealth program to improve diabetes self-management skills
    PRISCILLA E PEMU
    Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 30310, USA
    J Health Care Poor Underserved 22:146-64. 2011
    ..Requestors were more obese with worse A1C than others. Chronic care delivery scored average with high scores for counseling and problem solving but low scores for care coordination and follow up...
  28. ncbi request reprint Early and sustained benefit on event-free survival and heart failure hospitalization from fixed-dose combination of isosorbide dinitrate/hydralazine: consistency across subgroups in the African-American Heart Failure Trial
    Anne L Taylor
    Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA
    Circulation 115:1747-53. 2007
    ....
  29. pmc Association of distinct variants in SORL1 with cerebrovascular and neurodegenerative changes related to Alzheimer disease
    Karen T Cuenco
    Genetics Program, Department of Medicine, Room L320, Boston University School of Medicine, 715 Albany St, Boston, MA 02118, USA
    Arch Neurol 65:1640-8. 2008
    ....
  30. pmc New York Heart Association functional class predicts exercise parameters in the current era
    Stuart D Russell
    Department of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Am Heart J 158:S24-30. 2009
    ..Using baseline data from the HF-ACTION (Heart Failure and A Controlled Trial Investigating Outcomes of Exercise TraiNing) study, we examined this relationship...
  31. ncbi request reprint Outcomes by gender in the African-American Heart Failure Trial
    Anne L Taylor
    Department of Medicine, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Am Coll Cardiol 48:2263-7. 2006
    ..We therefore compared outcomes by gender and treatment...
  32. ncbi request reprint Efficacy and safety of fixed combinations of irbesartan/hydrochlorothiazide in older vs younger patients with hypertension uncontrolled with monotherapy
    William C Cushman
    University of Tennessee College of Medicine and Veterans Affairs Medical Center, Memphis, TN, USA
    Am J Geriatr Cardiol 17:27-36. 2008
    ..Irbesartan/HCTZ combination therapy allowed SBP goal attainment in 73% of patients aged 65 years or older whose hypertension was previously uncontrolled with antihypertensive monotherapy...
  33. ncbi request reprint Antihypertensive efficacy of Irbesartan/HCTZ in men and women with the metabolic syndrome and type 2 diabetes
    James R Sowers
    University of Missouri Columbia and Harry S Truman VA Medical Center, 65212, USA
    J Clin Hypertens (Greenwich) 8:470-80. 2006
    ..Irbesartan/HCTZ fixed combinations achieved SBP goals in over half of the T2DM patients and nearly three quarters of patients with the metabolic syndrome, with SBP uncontrolled on antihypertensive monotherapy...
  34. ncbi request reprint The efficacy and safety of low- and high-dose fixed combinations of irbesartan/hydrochlorothiazide in patients with uncontrolled systolic blood pressure on monotherapy: the INCLUSIVE trial
    Joel M Neutel
    Orange County Research Center, Tustin, CA 92780, USA
    J Clin Hypertens (Greenwich) 7:578-86. 2005
    ..Treatments were well tolerated. This irbesartan/HCTZ treatment regimen achieved SBP goals in more than 75% of patients uncontrolled on monotherapy...
  35. pmc Addressing health disparities through multi-institutional, multidisciplinary collaboratories
    Erik S Fleming
    Research Centers in Minority Institutions Translational Research Network, Charles R Drew University of Medicine and Science, Los Angeles, California 90062, USA
    Ethn Dis 18:S2-161-7. 2008
    ....
  36. ncbi request reprint Clinical assessment of the risk for sudden cardiac death in patients with sickle cell anemia
    John M Fontaine
    Drexe University College of Medicine, Philadelphia, PA 19102, USA
    J Natl Med Assoc 100:360-8. 2008
    ..An abnormal microvolt T-wave alternans (TWA) test is also a predictor of sudden cardiac death risk, but it has not been applied to this patient population...
  37. ncbi request reprint Working group 3: How to encourage more minorities to choose a career in cardiology
    Charles K Francis
    J Am Coll Cardiol 44:241-5. 2004