Gary A Bannon
Affiliation: Monsanto Company
- Evaluation of available IgE-binding epitope data and its utility in bioinformaticsGary A Bannon
Monsanto Company, St Louis, Missouri, USA
Mol Nutr Food Res 50:638-44. 2006..Finally, bioinformatics methods to assess protein allergenicity using knowledge of IgE-binding epitopes are discussed...
- What makes a food protein an allergen?Gary A Bannon
Monsanto, 800 N Lindbergh Boulevard, St Louis, MO 63167, USA
Curr Allergy Asthma Rep 4:43-6. 2004....
- Application of current allergy assessment guidelines to next-generation biotechnology-derived cropsGary A Bannon
Monsanto Co, Global Regulatory Sciences, 800 N Lindbergh Blvd, St Louis, MO 63167, USA
J AOAC Int 90:1492-9. 2007....
- The value of short amino acid sequence matches for prediction of protein allergenicityAndre Silvanovich
Monsanto Company, Product Characterization Center, Global Regulatory Affairs, St Louis, Missouri 63167, USA
Toxicol Sci 90:252-8. 2006....
- Vicilins: a case study in allergen pedigreesJames D Astwood
Product Safety Center, Monsanto, St Louis, MO 63167, USA
J Allergy Clin Immunol 110:26-7. 2002
- Characterization and crystal structure of lysine insensitive Corynebacterium glutamicum dihydrodipicolinate synthase (cDHDPS) proteinElena A Rice
Monsanto Company, 800 North Lindbergh Boulevard, St Louis, MO 63167, USA
Arch Biochem Biophys 480:111-21. 2008....
- Comparative potency of Ara h 1 and Ara h 2 in immunochemical and functional assays of allergenicityG William Palmer
Division of Allergy and Clinical Immunology, University of Colorado Health Sciences Center, Campus Box B164, 4200 E Ninth Avenue Denver, CO 80262, USA
Clin Immunol 115:302-12. 2005..This finding is different from what was predicted based on immunoblots or with the ImmunoCap assay...
- Allergenic characteristics of a modified peanut allergenNina King
Department of Biochemistry and Molecular Biology, Arkansas Children s Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA
Mol Nutr Food Res 49:963-71. 2005..In addition, the modified allergen released significantly lower amounts of beta-hexosaminidase, a marker for IgE-mediated RBL-2H3 degranulation, compared to the wild-type allergen...
- Modification of peanut allergen Ara h 3: effects on IgE binding and T cell stimulationPat Rabjohn
Department of Biochemistry and Molecular Biology, Arkansas Children s Hospital Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA
Int Arch Allergy Immunol 128:15-23. 2002..Mutational analysis of the Ara h 3 IgE-binding epitopes with synthetic peptides revealed that single amino acid changes at critical residues could diminish IgE binding...
- Animal models of food allergy: opportunities and barriersScott McClain
Curr Allergy Asthma Rep 6:141-4. 2006..Each model presents opportunities for and barriers to a fuller understanding of the allergic response. The conditions inherent to each model and the intended purpose of the study should therefore be considered prior to its use...
- Protein structure plays a critical role in peanut allergen stability and may determine immunodominant IgE-binding epitopesMoon Sen
Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
J Immunol 169:882-7. 2002..These results provide a link between allergen structure and the immunodominant IgE-binding epitopes within a population of food-allergic individuals...
- Serum testing of genetically modified soybeans with special emphasis on potential allergenicity of the heterologous protein CP4 EPSPSMichael Hoff
Department of Allergology, Paul Ehrlich Institute, Langen, Germany
Mol Nutr Food Res 51:946-55. 2007..These results indicate that the CP4 EPSPS protein does not bind significant quantities of IgE from two geographically distinct sensitive populations and there is no evidence for an increased allergenic potential of this biotech protein...
- Comparison of conventional FASTA identity searches with the 80 amino acid sliding window FASTA search for the elucidation of potential identities to known allergensGregory S Ladics
Dupont Pioneer Crop Genetics Regulatory Science and Registration, Wilmington, DE 19880, USA
Mol Nutr Food Res 51:985-98. 2007..It is recommended that the conventional FASTA analysis be conducted to compare identities of proteins to allergens...
- Human subjects without peanut allergy demonstrate T cell-dependent, TH2-biased, peanut-specific cytokine and chemokine responses independent of TH1 expressionTina B Thottingal
Department of Immunology, University of Manitoba, Winnipeg, Canada
J Allergy Clin Immunol 118:905-14. 2006..Most studies focus exclusively on serologic responses and individuals with peanut allergy...
- Monitoring peanut allergen in food products by measuring Ara h 1Anna Pomes
INDOOR Biotechnologies, Inc, Charlottesville, VA 22903, USA
J Allergy Clin Immunol 111:640-5. 2003..Peanut allergy is an important health problem in the United States, affecting approximately 0.6% of children. Inadvertent exposure to peanut is a risk factor for life-threatening food-induced anaphylaxis...
- A neonatal swine model for peanut allergyRicki M Helm
Division of Allergy Immunology, Department of Pediatrics, Arkansas Children s Hospital Research Institute, University of Arkansas for Medical Sciences, Little Rock 72201, USA
J Allergy Clin Immunol 109:136-42. 2002..As yet, no animal model has been developed that will completely mimic the physical, immunologic, and histologic features of food allergy...