Mark W Miller

Summary

Country: USA

Publications

  1. ncbi request reprint Multidimensional Personality Questionnaire profiles of veterans with traumatic combat exposure: externalizing and internalizing subtypes
    Mark W Miller
    National Center for Posttraumatic Stress Disorder, Veterans Affairs Boston Healthcare System, Division of Psychiatry, Boston University School of Medicine, 150 South Huntington Avenue 116B 2, Boston, Massachusetts, USA
    Psychol Assess 15:205-15. 2003
  2. ncbi request reprint Emotional-processing in posttraumatic stress disorder II: startle reflex modulation during picture processing
    Mark W Miller
    National Center for Posttraumatic Stress Disorder, Veterans Affairs Boston Healthcare System, Boston, MA 02130, USA
    J Abnorm Psychol 113:451-63. 2004
  3. ncbi request reprint Externalizing and internalizing subtypes of combat-related PTSD: a replication and extension using the PSY-5 scales
    Mark W Miller
    National Center for Posttraumatic Stress Disorder, Veterans Affairs Boston Healthcare System, 150 South Huntington Avenue 116B 2, Boston, MA 02130, USA
    J Abnorm Psychol 113:636-45. 2004
  4. pmc A dyadic analysis of the influence of trauma exposure and posttraumatic stress disorder severity on intimate partner aggression
    Erika J Wolf
    National Center for PTSD at VA Boston Healthcare System, Boston, MA 02130, USA
    J Trauma Stress 26:329-37. 2013
  5. pmc The structure of personality disorders in individuals with posttraumatic stress disorder
    Erika J Wolf
    National Center for PTSD at VA BostonHealthcare System, Boston, Massachusetts 02130, USA
    Personal Disord 2:261-78. 2011
  6. doi request reprint Attention-deficit/hyperactivity disorder comorbidity in a sample of veterans with posttraumatic stress disorder
    Kelly M Harrington
    MAVERIC, VA Boston Healthcare System, Boston, MA 02130, USA
    Compr Psychiatry 53:679-90. 2012
  7. pmc Corticotropin releasing hormone receptor 2 (CRHR-2) gene is associated with decreased risk and severity of posttraumatic stress disorder in women
    Erika J Wolf
    National Center for PTSD, VA Boston Healthcare System, Boston, Massachusetts Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts
    Depress Anxiety 30:1161-9. 2013
  8. pmc Psychometric properties of the Schedule for Nonadaptive and Adaptive Personality in a PTSD sample
    Erika J Wolf
    National Center for PTSD 116B 2, VA Boston Healthcare System, 150 South Huntington Avenue, Boston, MA 02130, USA
    Psychol Assess 23:911-24. 2011
  9. pmc Accelerated DNA methylation age: Associations with PTSD and neural integrity
    Erika J Wolf
    National Center for PTSD, Behavioral Science Division, VA Boston Healthcare System, Boston, MA, USA Department of Psychiatry, Boston University School of Medicine, Boston, MA, USA Electronic address
    Psychoneuroendocrinology 63:155-62. 2016
  10. pmc Alcohol and drug abuse among U.S. veterans: comparing associations with intimate partner substance abuse and veteran psychopathology
    Mark W Miller
    National Center for PTSD at VA Boston Healthcare System and Department of Psychiatry, Boston, MA 02130, USA
    J Trauma Stress 26:71-6. 2013

Detail Information

Publications44

  1. ncbi request reprint Multidimensional Personality Questionnaire profiles of veterans with traumatic combat exposure: externalizing and internalizing subtypes
    Mark W Miller
    National Center for Posttraumatic Stress Disorder, Veterans Affairs Boston Healthcare System, Division of Psychiatry, Boston University School of Medicine, 150 South Huntington Avenue 116B 2, Boston, Massachusetts, USA
    Psychol Assess 15:205-15. 2003
    ..These findings suggest that dispositions toward externalizing versus internalizing psychopathology may account for heterogeneity in the expression of posttraumatic responses, including patterns of comorbidity...
  2. ncbi request reprint Emotional-processing in posttraumatic stress disorder II: startle reflex modulation during picture processing
    Mark W Miller
    National Center for Posttraumatic Stress Disorder, Veterans Affairs Boston Healthcare System, Boston, MA 02130, USA
    J Abnorm Psychol 113:451-63. 2004
    ..These findings, along with augmented corrugator EMG reactivity during the same interval, suggest that trauma-related reexperiencing primes subsequent negative emotional responding in individuals with PTSD...
  3. ncbi request reprint Externalizing and internalizing subtypes of combat-related PTSD: a replication and extension using the PSY-5 scales
    Mark W Miller
    National Center for Posttraumatic Stress Disorder, Veterans Affairs Boston Healthcare System, 150 South Huntington Avenue 116B 2, Boston, MA 02130, USA
    J Abnorm Psychol 113:636-45. 2004
    ..These findings support the development of a personality-based typology of posttraumatic response designed to account for heterogeneity in the expression of PTSD and associated psychopathology...
  4. pmc A dyadic analysis of the influence of trauma exposure and posttraumatic stress disorder severity on intimate partner aggression
    Erika J Wolf
    National Center for PTSD at VA Boston Healthcare System, Boston, MA 02130, USA
    J Trauma Stress 26:329-37. 2013
    ..Results suggest it is important to consider the trauma histories and possible presence of PTSD in both partners as this may be a point of intervention when treating distressed couples...
  5. pmc The structure of personality disorders in individuals with posttraumatic stress disorder
    Erika J Wolf
    National Center for PTSD at VA BostonHealthcare System, Boston, Massachusetts 02130, USA
    Personal Disord 2:261-78. 2011
    ..These findings suggest continuity in the underlying structure of psychopathology across DSM-IV Axes I and II and provide empirical evidence of a pervasive, core disturbance in the boundary between self and other across the PDs...
  6. doi request reprint Attention-deficit/hyperactivity disorder comorbidity in a sample of veterans with posttraumatic stress disorder
    Kelly M Harrington
    MAVERIC, VA Boston Healthcare System, Boston, MA 02130, USA
    Compr Psychiatry 53:679-90. 2012
    ....
  7. pmc Corticotropin releasing hormone receptor 2 (CRHR-2) gene is associated with decreased risk and severity of posttraumatic stress disorder in women
    Erika J Wolf
    National Center for PTSD, VA Boston Healthcare System, Boston, Massachusetts Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts
    Depress Anxiety 30:1161-9. 2013
    ..CRH receptor-2 (CRHR-2) plays a role in attenuating biological responses to stressful life events and trauma, making the CRHR-2 gene a strong candidate to study in relationship to PTSD...
  8. pmc Psychometric properties of the Schedule for Nonadaptive and Adaptive Personality in a PTSD sample
    Erika J Wolf
    National Center for PTSD 116B 2, VA Boston Healthcare System, 150 South Huntington Avenue, Boston, MA 02130, USA
    Psychol Assess 23:911-24. 2011
    ..Overall, findings support the use of this measure in this population and contribute to our conceptualization of the association between temperament, PTSD, and Axis II psychopathology...
  9. pmc Accelerated DNA methylation age: Associations with PTSD and neural integrity
    Erika J Wolf
    National Center for PTSD, Behavioral Science Division, VA Boston Healthcare System, Boston, MA, USA Department of Psychiatry, Boston University School of Medicine, Boston, MA, USA Electronic address
    Psychoneuroendocrinology 63:155-62. 2016
    ..Accumulating evidence suggests that posttraumatic stress disorder (PTSD) may accelerate cellular aging and lead to premature morbidity and neurocognitive decline...
  10. pmc Alcohol and drug abuse among U.S. veterans: comparing associations with intimate partner substance abuse and veteran psychopathology
    Mark W Miller
    National Center for PTSD at VA Boston Healthcare System and Department of Psychiatry, Boston, MA 02130, USA
    J Trauma Stress 26:71-6. 2013
    ..Findings shed new light on the influence of relationship factors on veteran alcohol and drug use and underscore the importance of couples-oriented approaches to treating veterans with comorbid PTSD and substance abuse...
  11. pmc A latent class analysis of dissociation and posttraumatic stress disorder: evidence for a dissociative subtype
    Erika J Wolf
    National Center for PTSD, VA Boston Healthcare System, Massachusetts, USA
    Arch Gen Psychiatry 69:698-705. 2012
    ..The nature of the relationship of dissociation to posttraumatic stress disorder (PTSD) is controversial and of considerable clinical and nosologic importance...
  12. pmc Personality and the latent structure of PTSD comorbidity
    Mark W Miller
    National Center for PTSD at VA Boston Healthcare System, Boston University School of Medicine, Department of Psychiatry, USA
    J Anxiety Disord 26:599-607. 2012
    ..These results shed new light on the location of borderline personality disorder within the internalizing/externalizing model and clarify the relative influence of broad dimensions of personality on patterns of comorbidity...
  13. ncbi request reprint Structural equation modeling of associations among combat exposure, PTSD symptom factors, and Global Assessment of Functioning
    Mark W Miller
    National Center for Posttraumatic Stress Disorder, VA Boston Healthcare System, Boston, MA 02130, USA
    J Rehabil Res Dev 45:359-69. 2008
    ..However, only 17% of variance in GAF was accounted for by PTSD. The results raise concern about the use of the GAF score as a benchmark for quantifying combat PTSD-related functional impairment...
  14. pmc The internalizing and externalizing structure of psychiatric comorbidity in combat veterans
    Mark W Miller
    National Center for PTSD, VA Boston Healthcare System, Boston, MA 02130, USA
    J Trauma Stress 21:58-65. 2008
    ..These findings shed new light on the structure of psychiatric comorbidity in a treatment-seeking sample characterized by high rates of PTSD...
  15. doi request reprint Mild traumatic brain injury is associated with reduced cortical thickness in those at risk for Alzheimer's disease
    Jasmeet P Hayes
    National Center for PTSD, VA Boston Healthcare System, Boston, MA, USA
    Brain . 2017
    ..These results underscore the importance of documenting head injuries even within the mild range as they may interact with genetic risk to produce negative long-term health consequences such as neurodegenerative disease...
  16. pmc EPIGENETIC VARIATION AT SKA2 PREDICTS SUICIDE PHENOTYPES AND INTERNALIZING PSYCHOPATHOLOGY
    Naomi Sadeh
    National Center for PTSD, Behavioral Science Division, VA Boston Healthcare System, Boston, Massachusetts
    Depress Anxiety 33:308-15. 2016
    ..To examine the specificity and reliability of these findings, we examined associations between SKA2 DNA methylation, broad dimensions of psychiatric symptoms, and suicide phenotypes in adults with high levels of trauma exposure...
  17. doi request reprint The dissociative subtype of PTSD: a replication and extension
    Erika J Wolf
    National Center for PTSD at VA Boston Healthcare System, Boston, Massachusetts, USA
    Depress Anxiety 29:679-88. 2012
    ..The aim of this study was to evaluate the evidence for a dissociative subtype of PTSD in two independent samples and to examine the pattern of personality disorder (PD) comorbidity associated with the dissociative subtype of PTSD...
  18. doi request reprint Posttraumatic stress disorder: anxiety or traumatic stress disorder?
    Patricia A Resick
    National Center for PTSD, VA Boston Healthcare System, and Boston University School of Medicine, Boston, MA 02130, USA
    J Trauma Stress 22:384-90. 2009
    ..The authors conclude with the recommendation that PTSD be included among a new category of traumatic stress disorders in DSM-V...
  19. doi request reprint An evaluation of competing models for the structure of PTSD symptoms using external measures of comorbidity
    Mark W Miller
    National Center for PTSD, VA Boston Healthcare System and Boston University School of Medicine, 150 South Huntington Avenue, Boston, MA 02130, USA
    J Trauma Stress 23:631-8. 2010
    ..Findings raise questions about proposals to abandon the distinction between numbing and hyperarousal symptoms in favor of a dysphoria-based model...
  20. pmc Posttraumatic Stress Disorder as a Catalyst for the Association Between Metabolic Syndrome and Reduced Cortical Thickness
    Erika J Wolf
    National Center for PTSD, Boston, Massachusetts Department of Psychiatry, Boston, Massachusetts Electronic address
    Biol Psychiatry 80:363-71. 2016
    ..Given this, we evaluated 1) the association between MetS and neural integrity, indexed by cortical thickness; 2) the relationship between PTSD and MetS; and 3) whether PTSD was associated with cortical thickness indirectly through MetS...
  21. pmc The dopamine D3 receptor gene and posttraumatic stress disorder
    Erika J Wolf
    National Center for PTSD at VA Boston Healthcare System, Boston, Massachusetts, USA Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts, USA
    J Trauma Stress 27:379-87. 2014
    ....
  22. pmc The ankyrin-3 gene is associated with posttraumatic stress disorder and externalizing comorbidity
    Mark W Logue
    Biomedical Genetics, Department of Medicine, Boston University School of Medicine, Boston, MA, United States Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States
    Psychoneuroendocrinology 38:2249-57. 2013
    ....
  23. pmc Associations between Pittsburgh Sleep Quality Index factors and health outcomes in women with posttraumatic stress disorder
    Melynda D Casement
    National Center for PTSD at VA Boston Healthcare System and Boston University Medical Center, 150 S Huntington Ave 116B, Boston, MA 02130, USA
    Sleep Med 13:752-8. 2012
    ..This study examined the replicability of two- and three-factor models of the PSQI, as well as the relationship between PSQI factors and health outcomes, in a female sample with PTSD...
  24. pmc Personality-based latent classes of posttraumatic psychopathology: personality disorders and the internalizing/externalizing model
    Erika J Wolf
    National Center for PTSD, VA Boston Healthcare System, Boston, Massachusetts 02130, USA
    J Abnorm Psychol 121:256-62. 2012
    ..Findings support the reliability of this typology and support the relevance of the internalizing and externalizing model to the structure of personality disorders...
  25. ncbi request reprint PTSD and substance-related problems: the mediating roles of disconstraint and negative emotionality
    Mark W Miller
    National Center for PTSD, VA Boston Healthcare System, Boston, MA 02130, USA
    J Abnorm Psychol 115:369-79. 2006
    ..These findings indicate distinct pathways to different forms of substance-related problems in PTSD and underscore the role of personality in mediating these relationships...
  26. pmc The Dissociative Subtype of PTSD Scale: Initial Evaluation in a National Sample of Trauma-Exposed Veterans
    Erika J Wolf
    National Center for PTSD at VA Boston Healthcare System, Boston, MA, USA Boston University School of Medicine, Boston, MA, USA
    Assessment . 2015
    ..Overall, results provide initial psychometric support for the lifetime DSPS scales; additional research in clinical and community samples is needed to further validate the measure...
  27. pmc A novel locus in the oxidative stress-related gene ALOX12 moderates the association between PTSD and thickness of the prefrontal cortex
    Mark W Miller
    National Center for PTSD, Behavioral Science Division, VA Boston Healthcare System, Boston, MA, USA Department of Psychiatry, Boston University School of Medicine, Boston, MA, USA
    Psychoneuroendocrinology 62:359-65. 2015
    ..These findings illustrate a novel factor-analytic approach to neuroimaging-genetic analyses and provide new evidence for the possible involvement of oxidative stress in PTSD-related neurodegeneration. ..
  28. pmc A genome-wide association study of clinical symptoms of dissociation in a trauma-exposed sample
    Erika J Wolf
    National Center for PTSD, VA Boston Healthcare System, Boston, Massachusetts Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts
    Depress Anxiety 31:352-60. 2014
    ..This study examined genetic polymorphisms for association with the symptoms that define the dissociative subtype of PTSD using a genome-wide approach...
  29. pmc The retinoid-related orphan receptor alpha (RORA) gene and fear-related psychopathology
    Mark W Miller
    National Center for PTSD at VA Boston Healthcare System, Boston, MA, USA Department of Psychiatry, Boston University School of Medicine, Boston, MA, USA Electronic address
    J Affect Disord 151:702-8. 2013
    ..This study followed on findings from a recent genome-wide association study of PTSD that implicated the retinoid-related orphan receptor alpha (RORA) gene (Logue et al., 2012) by examining its relationship to broader array of disorders...
  30. pmc Emotional processing in PTSD: heightened negative emotionality to unpleasant photographic stimuli
    Erika J Wolf
    National Center for PTSD, Veterans Affairs Boston Healthcare System, Boston, Massachusetts 02130, USA
    J Nerv Ment Dis 197:419-26. 2009
    ..Findings raise questions about the sensitivity of the International Affective Picture System rating protocol for the assessment of PTSD-related emotional numbing...
  31. pmc Intimate partner and general aggression perpetration among combat veterans presenting to a posttraumatic stress disorder clinic
    Casey T Taft
    National Center for PTSD, VA Boston Healthcare System, Boston, MA 02130, USA
    Am J Orthopsychiatry 79:461-8. 2009
    ..Findings indicate a need for additional aggression screening and intervention development for this population, and highlight the targeting of heightened arousal and lack of behavioral control in aggression interventions...
  32. pmc Posttraumatic stress disorder and the genetic structure of comorbidity
    Erika J Wolf
    National Center for PTSD, VA Boston Healthcare System and Department of Psychology, Boston University, Boston, MA, USA
    J Abnorm Psychol 119:320-30. 2010
    ..Shared genetic variance across the 2 dimensions explained 67% of their phenotypic correlation (r = .52). These findings have implications for conceptualizations of the etiology of PTSD and its location in an empirically based nosology...
  33. ncbi request reprint On comparing competing models of PTSD: response to Simms
    Mark W Miller
    National Center for PTSD, VA Boston Healthcare System and Boston University School of Medicine, 150 South Huntington Avenue, Boston, MA 02130, USA
    J Trauma Stress 23:642-4. 2010
    ..The author concludes by underscoring the need for future research to place greater emphasis on examining the external correlates of alternative models of the factor structure of PTSD...
  34. pmc Association of eating disorder symptoms with internalizing and externalizing dimensions of psychopathology among men and women
    Karen S Mitchell
    National Center for PTSD at VA Boston Healthcare System, Boston, Massachusetts Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts
    Int J Eat Disord 47:860-9. 2014
    ..We examined the location of anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED) symptoms within this model of psychopathology among a sample of veterans, a population traditionally understudied in EDs...
  35. pmc The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration
    Mark W Logue
    1 Research, VA Boston Healthcare System, Boston, MA, USA 2 Biomedical Genetics, Boston University School of Medicine, Boston, MA, USA 3 Biostatistics, Boston University School of Public Health, Boston, MA, USA
    Neuropsychopharmacology 40:2287-97. 2015
    ....
  36. pmc An analysis of gene expression in PTSD implicates genes involved in the glucocorticoid receptor pathway and neural responses to stress
    Mark W Logue
    Research Service, VA Boston Healthcare System, Boston, MA, United States Biomedical Genetics, Boston University School of Medicine, Boston, MA, United States Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States Electronic address
    Psychoneuroendocrinology 57:1-13. 2015
    ..Finally, we found that the set of differentially expressed genes from the discovery sample was enriched for genes responsive to glucocorticoid signaling with most showing reduced expression in PTSD cases compared to controls. ..
  37. doi request reprint Psychological effects of the marathon bombing on Boston-area veterans with posttraumatic stress disorder
    Mark W Miller
    National Center for PTSD at VA Boston Healthcare System, Boston, Massachusetts, USA Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts, USA
    J Trauma Stress 26:762-6. 2013
    ..008, respectively). Findings of this study should raise awareness of the potential impact of terror attacks, mass shootings, and other events of this type on the well-being of individuals with histories of trauma and/or pre-existing PTSD...
  38. ncbi request reprint Affective imagery and the startle response: probing mechanisms of modulation during pleasant scenes, personal experiences, and discrete negative emotions
    Mark W Miller
    Boston University School of Medicine, Massachusetts, USA
    Psychophysiology 39:519-29. 2002
    ..The findings also indicate that fear and anger are differentiable in terms of affective report, cardiac mobilization, and expressive behavior, but not at the primary motivational level at which reflex priming occurs...
  39. pmc Internalizing and externalizing subtypes in female sexual assault survivors: implications for the understanding of complex PTSD
    Mark W Miller
    National Center for PTSD, VA Boston Healthcare System, and Boston University, MA 02130, USA
    Behav Ther 38:58-71. 2007
    ....
  40. pmc Diurnal variation of the startle reflex in relation to HPA-axis activity in humans
    Mark W Miller
    National Center for PTSD, VA Boston Healthcare System and Department of Psychiatry, Boston University, Boston, Massachusetts 02130, USA
    Psychophysiology 43:297-301. 2006
    ....
  41. pmc Neurobiological indicators of disinhibition in posttraumatic stress disorder
    Naomi Sadeh
    National Center for PTSD, Behavioral Science Division, VA Boston Healthcare System, Boston, MA, USA
    Hum Brain Mapp 36:3076-86. 2015
    ..Furthermore, aberrant coupling between frontal regions and networks involved in selective attention, memory/learning, and response preparation suggest disruptions in functional connectivity may also play a role...
  42. pmc Negative emotionality and disconstraint influence PTSD symptom course via exposure to new major adverse life events
    Naomi Sadeh
    National Center for Posttraumatic Stress Disorder at Veterans Affairs Boston Healthcare System, 150 South Huntington Avenue, Boston, MA 02130, United States Boston University School of Medicine, Department of Psychiatry, 715 Albany Street, M 8th Floor, Boston, MA 02118, United States Electronic address
    J Anxiety Disord 31:20-7. 2015
    ..Results indicate that high negative affect and disconstraint influence the course of PTSD symptoms by increasing exposure to stressful life events. ..
  43. pmc Differential etiology of posttraumatic stress disorder with conduct disorder and major depression in male veterans
    Qiang Fu
    Department of Community Health, Saint Louis University School of Public Health, St Louis, Missouri 63104, USA
    Biol Psychiatry 62:1088-94. 2007
    ..Epidemiologic studies reveal that posttraumatic stress disorder (PTSD) is highly comorbid with both conduct disorder and major depression in men. The genetic and environmental etiology of this comorbidity has not been examined...
  44. pmc Military-related PTSD, current disability policies, and malingering
    Brian P Marx
    Am J Public Health 98:773-4; author reply 774-5. 2008