W H Cooke

Summary

Affiliation: Michigan Technological University
Country: USA

Publications

  1. ncbi request reprint Heart rate variability and spontaneous baroreflex sequences: implications for autonomic monitoring during hemorrhage
    William H Cooke
    U S Army Institute of Surgical Research, Fort Sam Houston, Texas, USA
    J Trauma 58:798-805. 2005
  2. ncbi request reprint Power spectral analysis imperfectly informs changes in sympathetic traffic during acute simulated microgravity
    W H Cooke
    Center for Biomedical Engineering, Michigan Technological University, 1400 Townsend Dr, Houghton, MI 49931, USA
    Aviat Space Environ Med 71:1232-8. 2000
  3. ncbi request reprint Does the menstrual cycle influence the sensitivity of vagally mediated baroreflexes?
    William H Cooke
    Department of Biomedical Engineering, Michigan Technological University, Houghton 49931, USA
    Clin Sci (Lond) 102:639-44. 2002
  4. ncbi request reprint Effects of exercise training on cardiovagal and sympathetic responses to Valsalva's maneuver
    William H Cooke
    Department of Biomedical Engineering, Michigan Technological University, Houghton 49931, USA
    Med Sci Sports Exerc 34:928-35. 2002
  5. ncbi request reprint Muscle sympathetic nerve activation during the Valsalva maneuver: interpretive and analytical caveats
    William H Cooke
    Department of Biomedical Engineering, Michigan Technological University, Houghton, MI 49931, USA
    Aviat Space Environ Med 74:731-7. 2003
  6. ncbi request reprint Topical anesthetic before microneurography decreases pain without affecting sympathetic traffic
    W H Cooke
    Center for Biomedical Engineering, Michigan Technological University, 1400 Townsend Dr, Houghton, MI 49931, USA
    Auton Neurosci 86:120-6. 2000
  7. ncbi request reprint Nine months in space: effects on human autonomic cardiovascular regulation
    W H Cooke
    Center for Biomedical Engineering, Michigan Technological University, Houghton, Michigan 49931, USA
    J Appl Physiol (1985) 89:1039-45. 2000
  8. pmc Human responses to upright tilt: a window on central autonomic integration
    W H Cooke
    Department of Medicine and Physiology, Hunter Holmes McGuire Department of Veterans Affairs Medical Center and Medical College of Virginia at Virginia Commonwealth University, Richmond, VA 23249, USA
    J Physiol 517:617-28. 1999
  9. ncbi request reprint Respiratory modulation of human autonomic rhythms
    L J Badra
    Department of Medicine, Hunter Holmes McGuire Department of Veterans Affairs Medical Center and Medical College of Virginia at Virginia Commonwealth University, Richmond, Virginia 23249, USA
    Am J Physiol Heart Circ Physiol 280:H2674-88. 2001
  10. ncbi request reprint Controlled breathing protocols probe human autonomic cardiovascular rhythms
    W H Cooke
    Department of Medicine, Medical College of Virginia of Virginia Commonwealth University, Richmond, USA
    Am J Physiol 274:H709-18. 1998

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Heart rate variability and spontaneous baroreflex sequences: implications for autonomic monitoring during hemorrhage
    William H Cooke
    U S Army Institute of Surgical Research, Fort Sam Houston, Texas, USA
    J Trauma 58:798-805. 2005
    ..The purpose of this study was twofold: (1) to track changes in autonomic function induced by a model of hemorrhage, and (2) to determine whether measures of autonomic function are reliable without strict control of breathing...
  2. ncbi request reprint Power spectral analysis imperfectly informs changes in sympathetic traffic during acute simulated microgravity
    W H Cooke
    Center for Biomedical Engineering, Michigan Technological University, 1400 Townsend Dr, Houghton, MI 49931, USA
    Aviat Space Environ Med 71:1232-8. 2000
    ..05). We conclude that non-invasive frequency-domain estimates do not adequately reveal subtle changes in sympathetic traffic during acute, simulated microgravity...
  3. ncbi request reprint Does the menstrual cycle influence the sensitivity of vagally mediated baroreflexes?
    William H Cooke
    Department of Biomedical Engineering, Michigan Technological University, Houghton 49931, USA
    Clin Sci (Lond) 102:639-44. 2002
    ..18). These findings are consistent with the notion that beat-to-beat vagal-cardiac regulation does not change over the course of the normal menstrual cycle...
  4. ncbi request reprint Effects of exercise training on cardiovagal and sympathetic responses to Valsalva's maneuver
    William H Cooke
    Department of Biomedical Engineering, Michigan Technological University, Houghton 49931, USA
    Med Sci Sports Exerc 34:928-35. 2002
    ..We tested the hypothesis that a strictly-controlled program of aerobic conditioning would increase vagal and decrease sympathetic responses to Valsalva straining...
  5. ncbi request reprint Muscle sympathetic nerve activation during the Valsalva maneuver: interpretive and analytical caveats
    William H Cooke
    Department of Biomedical Engineering, Michigan Technological University, Houghton, MI 49931, USA
    Aviat Space Environ Med 74:731-7. 2003
    ..We investigated the relationship between arterial pressure and muscle sympathetic nerve activity (MSNA) to test the hypothesis that the Valsalva maneuver may be used to estimate magnitudes of sympathetic baroreflex activation...
  6. ncbi request reprint Topical anesthetic before microneurography decreases pain without affecting sympathetic traffic
    W H Cooke
    Center for Biomedical Engineering, Michigan Technological University, 1400 Townsend Dr, Houghton, MI 49931, USA
    Auton Neurosci 86:120-6. 2000
    ..05). These data show that use of EMLA cream prior to microneurography is innocuous, and do not support the hypothesis that baseline sympathetic traffic is increased by pain or discomfort associated with microneurography...
  7. ncbi request reprint Nine months in space: effects on human autonomic cardiovascular regulation
    W H Cooke
    Center for Biomedical Engineering, Michigan Technological University, Houghton, Michigan 49931, USA
    J Appl Physiol (1985) 89:1039-45. 2000
    ..Our results suggest that long-duration spaceflight reduces vagal-cardiac nerve traffic and decreases vagal baroreflex gain and that these changes may persist as long as 2 wk after return to Earth...
  8. pmc Human responses to upright tilt: a window on central autonomic integration
    W H Cooke
    Department of Medicine and Physiology, Hunter Holmes McGuire Department of Veterans Affairs Medical Center and Medical College of Virginia at Virginia Commonwealth University, Richmond, VA 23249, USA
    J Physiol 517:617-28. 1999
    ....
  9. ncbi request reprint Respiratory modulation of human autonomic rhythms
    L J Badra
    Department of Medicine, Hunter Holmes McGuire Department of Veterans Affairs Medical Center and Medical College of Virginia at Virginia Commonwealth University, Richmond, Virginia 23249, USA
    Am J Physiol Heart Circ Physiol 280:H2674-88. 2001
    ..Most importantly, our results indicate that correlations among autonomic and hemodynamic rhythms vary over time and frequency, and, thus, are facultative rather than fixed...
  10. ncbi request reprint Controlled breathing protocols probe human autonomic cardiovascular rhythms
    W H Cooke
    Department of Medicine, Medical College of Virginia of Virginia Commonwealth University, Richmond, USA
    Am J Physiol 274:H709-18. 1998
    ....
  11. pmc Human baroreflex rhythms persist during handgrip and muscle ischaemia
    D L Eckberg
    Department of Medicine and Physiology, Hunter Holmes McGuire Department of Veterans Affairs Medical Center, Richmond, VA, USA Medical College of Virginia at Virginia Commonwealth University, Richmond, VA, USA
    Acta Physiol (Oxf) 209:114-23. 2013
    ..To determine whether physiological, rhythmic fluctuations of vagal baroreflex gain persist during exercise, post-exercise ischaemia and recovery...
  12. pmc Influence of microgravity on astronauts' sympathetic and vagal responses to Valsalva's manoeuvre
    James F Cox
    Department of Medicine and Physiology, Hunter Holmes McGuire Veterans Affairs Medical Center and Medical College of Virginia at Virginia Commonwealth University, Richmond, Virginia, USA 23249
    J Physiol 538:309-20. 2002
    ..This and earlier research suggest that exposure of healthy humans to microgravity augments arterial pressure and sympathetic responses to Valsalva straining and differentially reduces vagal, but not sympathetic baroreflex gain...
  13. ncbi request reprint Spontaneous 'baroreflex sequences' occur as deterministic functions of breathing phase
    Brian W Rothlisberger
    Department of Medicine, Hunter Homes McGuire Department of Veterans Affairs Medical Center and Medical College of Virginia at Virginia Commonwealth University, Richmond, VA 23225, USA
    Clin Physiol Funct Imaging 23:307-13. 2003
    ....
  14. ncbi request reprint Vestibulosympathetic reflex during mental stress
    Jason R Carter
    Department of Biological Sciences, Michigan Technological University, Houghton, Michigan 49931, USA
    J Appl Physiol (1985) 93:1260-4. 2002
    ..We conclude that the interaction for MSNA and arterial pressure is additive during combined vestibular and mental stimulation. Therefore, vestibular- and stress-mediated increases of MSNA appear to occur independently in humans...
  15. ncbi request reprint Forearm neurovascular responses during mental stress and vestibular activation
    Jason R Carter
    Department of Biological Sciences, Michigan Technological University, Houghton, Michigan 49931, USA
    Am J Physiol Heart Circ Physiol 288:H904-7. 2005
    ..Activation of the VSR prevented forearm vasodilation during MS, suggesting that activation of the VSR may help protect against stress-induced syncope...
  16. ncbi request reprint Dynamic cerebral autoregulation is preserved during acute head-down tilt
    William H Cooke
    Dept of Biomedical Engineering, Michigan Technological University, 1400 Townsend Dr, Houghton, MI 49931, USA
    J Appl Physiol (1985) 95:1439-45. 2003
    ..Our results show that in healthy humans, mild physiological manipulation of autonomic activity with acute head-down tilt has no effect on the ability of the cerebral vasculature to regulate flow velocity...
  17. ncbi request reprint Does nitric oxide buffer arterial blood pressure variability in humans?
    William H Cooke
    Department of Biomedical Engineering and Biological Sciences, Michigan Technological University, Houghton, Michigan 49931, USA
    J Appl Physiol 93:1466-70. 2002
    ....
  18. ncbi request reprint Sympathetic nerve activity and heart rate variability during severe hemorrhagic shock in sheep
    Andriy I Batchinsky
    U S Army Institute of Surgical Research, 3400 Rawley E Chambers Avenue, Building 3611, Fort Sam Houston, Texas 78234 6315, USA
    Auton Neurosci 136:43-51. 2007
    ..In this study we explored direct and indirect measures of autonomic nervous system function, as well as changes in cardiovascular complexity, during hemorrhagic shock (HS)...
  19. doi request reprint Breathing through an inspiratory threshold device improves stroke volume during central hypovolemia in humans
    Kathy L Ryan
    U S Army Institute of Surgical Research, 3400 Rawley E Chambers Avenue, Fort Sam Houston, TX 78234 6315, USA
    J Appl Physiol (1985) 104:1402-9. 2008
    ....
  20. doi request reprint Autonomic compensation to simulated hemorrhage monitored with heart period variability
    William H Cooke
    Department of Health and Kinesiology, University of Texas at San Antonio, San Antonio, TX 78249, USA
    Crit Care Med 36:1892-9. 2008
    ..To test the hypothesis that components of heart period variability track autonomic function during simulated hemorrhage in humans...
  21. ncbi request reprint Arterial pulse pressure and its association with reduced stroke volume during progressive central hypovolemia
    Victor A Convertino
    US Army Institute of Surgical Research, Fort Sam Houston, Texas 78234 6315, USA
    J Trauma 61:629-34. 2006
    ....
  22. ncbi request reprint Strength training does not affect vagal-cardiac control or cardiovagal baroreflex sensitivity in young healthy subjects
    William H Cooke
    U S Army Institute of Surgical Research, 3400 Rawley E Chambers Ave Bld 3611, Fort Sam Houston, Texas 78234 6315, USA
    Eur J Appl Physiol 93:719-25. 2005
    ....
  23. ncbi request reprint Human cerebrovascular and autonomic rhythms during vestibular activation
    William H Cooke
    U S Army Institute of Surgical Research, Rawley E Chambers Ave Bld 3611, Fort Sam Houston, TX 78234 6315, USA
    Am J Physiol Regul Integr Comp Physiol 286:R838-43. 2004
    ..These findings support the concept that vestibular-autonomic interactions independently and redundantly serve to maintain steady-state hemodynamics...
  24. ncbi request reprint Effects of inspiratory impedance on the carotid-cardiac baroreflex response in humans
    Victor A Convertino
    US Army Institute of Surgical Research, 3400 Rawley E Chambers Avenue Building 3611, Fort Sam Houston TX 78234 6315, USA
    Clin Auton Res 14:240-8. 2004
    ..This resetting of the cardiac baroreflex may represent a mechanism that allows blood pressure to increase without a reflex-mediated reduction in HR...
  25. ncbi request reprint Strength training reduces arterial blood pressure but not sympathetic neural activity in young normotensive subjects
    Jason R Carter
    Department of Biomedical Engineering and Biological Sciences, Michigan Technological University, Houghton, Michigan 49931, USA
    J Appl Physiol 94:2212-6. 2003
    ....
  26. pmc Human muscle sympathetic neural and haemodynamic responses to tilt following spaceflight
    Benjamin D Levine
    Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas and the University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75231, USA
    J Physiol 538:331-40. 2002
    ..We conclude that after 16 days of spaceflight, muscle sympathetic nerve responses to upright tilt are normal...
  27. ncbi request reprint Influence of progressive central hypovolemia on Hölder exponent distributions of cardiac interbeat intervals
    Bruce J West
    Department of Physics, Duke University, Durham, NC 27708, USA
    Ann Biomed Eng 32:1077-87. 2004
    ..The results suggest that autonomic neural mechanism driving cardiac interbeat intervals during central hypovolemia go through various levels of multifractality, as determined by Hölder exponent distributions...
  28. ncbi request reprint Head rotation during upright tilt increases cardiovagal baroreflex sensitivity
    William H Cooke
    Laboratory for Applied Autonomic Neurophysiology, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA
    Aviat Space Environ Med 78:463-9. 2007
    ..The purpose of this study was to determine the effects of voluntary head rotation on autonomic function during upright tilt...
  29. ncbi request reprint Prehospital loss of R-to-R interval complexity is associated with mortality in trauma patients
    Andriy I Batchinsky
    US Army Institute of Surgical Research, Fort Sam Houston, Texas 78234 6315, USA
    J Trauma 63:512-8. 2007
    ..To improve our ability to identify physiologic deterioration caused by critical injury, we applied nonlinear analysis to the R-to-R interval (RRI) of the electrocardiogram of prehospital trauma patients...
  30. ncbi request reprint Oxygen saturation determined from deep muscle, not thenar tissue, is an early indicator of central hypovolemia in humans
    Babs R Soller
    Department of Anesthesiology, University of Massachusetts Medical School, Worcester, MA, USA
    Crit Care Med 36:176-82. 2008
    ....
  31. pmc Cardiovascular and sympathetic neural responses to handgrip and cold pressor stimuli in humans before, during and after spaceflight
    Qi Fu
    Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, 7232 Greenville Avenue, Suite 435, Dallas, TX 75231, USA
    J Physiol 544:653-64. 2002
    ..We conclude that modulation of muscle sympathetic neural outflow by muscle metaboreceptors and skin nociceptors is preserved during short duration spaceflight...
  32. ncbi request reprint Autonomic neural control and implications for remote medical monitoring in space
    William H Cooke
    University of Texas at San Antonio, Department of Health and Kinesiology, One UTSA Circle, San Antonio, TX 78249, USA
    J Gravit Physiol 14:P43-6. 2007
    ..The focus of this brief review is to introduce potential methods of monitoring astronaut status remotely from simple ECG recordings...
  33. doi request reprint Physiological and medical monitoring for en route care of combat casualties
    Victor A Convertino
    US Army Institute of Surgical Research, Fort Sam Houston, TX 78234 6315, USA
    J Trauma 64:S342-53. 2008
    ....
  34. ncbi request reprint Inspiratory resistance, cerebral blood flow velocity, and symptoms of acute hypotension
    Caroline A Rickards
    U S Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA
    Aviat Space Environ Med 79:557-64. 2008
    ....
  35. ncbi request reprint Combat stress or hemorrhage? Evidence for a decision-assist algorithm for remote triage
    Caroline A Rickards
    U S Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA
    Aviat Space Environ Med 79:670-6. 2008
    ..The RRI HF and PP were used because of their ability to track central hypovolemia...
  36. ncbi request reprint Association between vasovagal hypotension and low sympathetic neural activity during presyncope
    William H Cooke
    Departments of Biomedical Engineering and Biological Sciences, Michigan Technological University, Houghton, MI 49931, USA
    Clin Auton Res 12:483-6. 2002
    ..The data from this case report question the notion that orthostatic hypotension occurs due to inadequate sympathetic neural activation during orthostatic stress in apparently normal, healthy subjects...
  37. ncbi request reprint Inspiratory resistance maintains arterial pressure during central hypovolemia: implications for treatment of patients with severe hemorrhage
    Victor A Convertino
    U S Army Institute of Surgical Research, Fort Sam Houston, TX, USA
    Crit Care Med 35:1145-52. 2007
    ....
  38. ncbi request reprint Stroke volume and sympathetic responses to lower-body negative pressure reveal new insight into circulatory shock in humans
    Victor A Convertino
    US Army Institute of Surgical Research, Fort Sam, 3400 Rawley E Chambers Avenue, Fort Sam Houston, TX 78234 6315, USA
    Auton Neurosci 111:127-34. 2004
    ..Sympathetic withdrawal rather than hypoadrenergic function may represent a fundamental mechanism for the development of circulatory shock...
  39. ncbi request reprint Inspiratory resistance as a potential treatment for orthostatic intolerance and hemorrhagic shock
    Victor A Convertino
    US Army Institute of Surgical Research, Fort Sam Houston, TX 78234 6315, USA
    Aviat Space Environ Med 76:319-25. 2005
    ..In this brief review, we present evidence which supports further consideration of using inspiratory resistance as a countermeasure against circulatory collapse associated with orthostatic instability and hemorrhagic shock...
  40. ncbi request reprint Manual vital signs reliably predict need for life-saving interventions in trauma patients
    John B Holcomb
    US Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA
    J Trauma 59:821-8; discussion 828-9. 2005
    ..In this study, we determined whether the addition of diagnostic equipment improved the predictive power of vital signs and scores obtained only by physical examination...
  41. ncbi request reprint Heart rate variability and its association with mortality in prehospital trauma patients
    William H Cooke
    Department of Health and Kinesiology, The University of Texas at San Antonio, San Antonio, Texas 78249, USA
    J Trauma 60:363-70; discussion 370. 2006
    ..The purpose of this study was to assess heart rate variability and its association with mortality in prehospital trauma patients...
  42. ncbi request reprint Lower body negative pressure as a model to study progression to acute hemorrhagic shock in humans
    William H Cooke
    US Army Institute of Surgical Research, Fort Sam Houston, TX 78234 6315, USA
    J Appl Physiol (1985) 96:1249-61. 2004
    ..Such experiments could lead to clinical algorithms that identify bleeding victims who will likely progress to hemorrhagic shock and require lifesaving intervention(s)...
  43. ncbi request reprint R-wave amplitude in lead II of an electrocardiograph correlates with central hypovolemia in human beings
    John G McManus
    U S Army Institute of Surgical Research, 3400 Rawley E Chambers Avenue, Fort Sam Houston, TX 78234 6513
    Acad Emerg Med 13:1003-10. 2006
    ..In this investigation, we used graded central hypovolemia in adult volunteer subjects to test the hypothesis that moderate reductions in central blood volume increases R-wave amplitude in lead II of an ECG...
  44. ncbi request reprint Heart period variability in trauma patients may predict mortality and allow remote triage
    William H Cooke
    Department of Health and Kinesiology, The University of Texas at San Antonio, San Antonio, TX 78249, USA
    Aviat Space Environ Med 77:1107-12. 2006
    ..We tested the hypothesis that survival is associated with low relative HF/LF, and death is associated with high relative HF/LF...
  45. pmc Human cerebral autoregulation before, during and after spaceflight
    Ken Ichi Iwasaki
    Institute for Exercise and Environmental Medicine, 7232 Greenville Avenue, Suite 435, Dallas, TX 75231, USA
    J Physiol 579:799-810. 2007
    ..We conclude that human cerebral autoregulation is preserved, and possibly even improved, by short-duration spaceflight...
  46. ncbi request reprint Loss of complexity characterizes the heart rate response to experimental hemorrhagic shock in swine
    Andriy I Batchinsky
    U S Army Institute of Surgical Research, Fort Sam Houston, TX, USA
    Crit Care Med 35:519-25. 2007
    ....
  47. ncbi request reprint Inspiratory resistance delays the reporting of symptoms with central hypovolemia: association with cerebral blood flow
    Caroline A Rickards
    U S Army Institute of Surgical Research, 3400 Rawley E Chambers Ave, Fort Sam Houston, TX 78234 6315, USA
    Am J Physiol Regul Integr Comp Physiol 293:R243-50. 2007
    ....