Anuradha Gopalan

Summary

Affiliation: Memorial Sloan-Kettering Cancer Center
Country: USA

Publications

  1. pmc TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy
    Anuradha Gopalan
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Cancer Res 69:1400-6. 2009
  2. pmc TMPRSS2-ERG rearrangement in dominant anterior prostatic tumours: incidence and correlation with ERG immunohistochemistry
    Anuradha Gopalan
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Histopathology 63:279-86. 2013
  3. doi request reprint Role of immunohistochemistry in the evaluation of needle core biopsies in adult renal cortical tumors: an ex vivo study
    Hikmat A Al-Ahmadie
    Departments of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Surg Pathol 35:949-61. 2011
  4. pmc TMPRSS2-ERG gene fusion is associated with low Gleason scores and not with high-grade morphological features
    Samson W Fine
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Mod Pathol 23:1325-33. 2010
  5. doi request reprint Epithelioid angiomyolipoma of the kidney: pathological features and clinical outcome in a series of consecutively resected tumors
    Wenlei He
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Mod Pathol 26:1355-64. 2013
  6. doi request reprint Prognostic impact of subclassification of radical prostatectomy positive margins by linear extent and Gleason grade
    Kazuma Udo
    Department of Surgery Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    J Urol 189:1302-7. 2013
  7. pmc ETS rearrangements and prostate cancer initiation
    Brett S Carver
    Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Nature 457:E1; discussion E2-3. 2009
  8. doi request reprint Chromophobe renal cell carcinoma: a clinicopathologic study of 203 tumors in 200 patients with primary resection at a single institution
    Christopher G Przybycin
    Department of Pathology, Urology Service, Memorial Sloan Kettering Cancer Center New York, NY 10065, USA
    Am J Surg Pathol 35:962-70. 2011
  9. doi request reprint Anterior-predominant prostatic tumors: zone of origin and pathologic outcomes at radical prostatectomy
    Hikmat A Al-Ahmadie
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 32:229-35. 2008
  10. doi request reprint Clear-cell papillary renal cell carcinoma: molecular and immunohistochemical analysis with emphasis on the von Hippel-Lindau gene and hypoxia-inducible factor pathway-related proteins
    Stephen M Rohan
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Mod Pathol 24:1207-20. 2011

Collaborators

Detail Information

Publications30

  1. pmc TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy
    Anuradha Gopalan
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Cancer Res 69:1400-6. 2009
    ....
  2. pmc TMPRSS2-ERG rearrangement in dominant anterior prostatic tumours: incidence and correlation with ERG immunohistochemistry
    Anuradha Gopalan
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Histopathology 63:279-86. 2013
    ..To study prostate cancer zonal differences in TMPRSS2-ERG gene rearrangement...
  3. doi request reprint Role of immunohistochemistry in the evaluation of needle core biopsies in adult renal cortical tumors: an ex vivo study
    Hikmat A Al-Ahmadie
    Departments of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Surg Pathol 35:949-61. 2011
    ..Both extent and patterns must be considered for a definitive diagnosis...
  4. pmc TMPRSS2-ERG gene fusion is associated with low Gleason scores and not with high-grade morphological features
    Samson W Fine
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Mod Pathol 23:1325-33. 2010
    ..These findings indicate that translocation/deletion of TMPRSS2-ERG is not associated with histological features of aggressive prostate cancer...
  5. doi request reprint Epithelioid angiomyolipoma of the kidney: pathological features and clinical outcome in a series of consecutively resected tumors
    Wenlei He
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Mod Pathol 26:1355-64. 2013
    ....
  6. doi request reprint Prognostic impact of subclassification of radical prostatectomy positive margins by linear extent and Gleason grade
    Kazuma Udo
    Department of Surgery Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    J Urol 189:1302-7. 2013
    ..We evaluated the relationship of progression to positive surgical margin linear length and Gleason grade at a positive surgical margin...
  7. pmc ETS rearrangements and prostate cancer initiation
    Brett S Carver
    Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Nature 457:E1; discussion E2-3. 2009
    ..To this end, we demonstrate that the prostate-specific overexpression of ERG does not initiate prostate tumorigenesis...
  8. doi request reprint Chromophobe renal cell carcinoma: a clinicopathologic study of 203 tumors in 200 patients with primary resection at a single institution
    Christopher G Przybycin
    Department of Pathology, Urology Service, Memorial Sloan Kettering Cancer Center New York, NY 10065, USA
    Am J Surg Pathol 35:962-70. 2011
    ..On the basis of this long follow-up on a large number of cases, chromophobes seem to have better clinical outcomes than those reported for clear cell and papillary RCCs...
  9. doi request reprint Anterior-predominant prostatic tumors: zone of origin and pathologic outcomes at radical prostatectomy
    Hikmat A Al-Ahmadie
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 32:229-35. 2008
    ..Given these similarities, long-term clinical outcomes and future molecular analyses will be necessary to assess whether true differences in biology and behavior exist between tumors of TZ and APZ origin...
  10. doi request reprint Clear-cell papillary renal cell carcinoma: molecular and immunohistochemical analysis with emphasis on the von Hippel-Lindau gene and hypoxia-inducible factor pathway-related proteins
    Stephen M Rohan
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Mod Pathol 24:1207-20. 2011
    ..The co-expression of CA9, HIF-1╬▒, and GLUT-1 in the absence of VHL gene alterations in clear-cell papillary renal cell carcinoma suggests activation of the HIF pathway by non-VHL-dependent mechanisms...
  11. doi request reprint Primary retroperitoneal lymph node dissection in low-stage testicular germ cell tumors: a detailed pathologic study with clinical outcome analysis with special emphasis on patients who did not receive adjuvant therapy
    Hikmat A Al-Ahmadie
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY
    Urology 82:1341-6. 2013
    ....
  12. pmc Integrative genomic profiling of human prostate cancer
    Barry S Taylor
    Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
    Cancer Cell 18:11-22. 2010
    ..The genomic and clinical outcome data from these patients are now made available as a public resource...
  13. pmc Do prostatic transition zone tumors have a distinct morphology?
    Joaquin J Garcia
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York City, NY 10021, USA
    Am J Surg Pathol 32:1709-14. 2008
    ..Given this lack of specificity, caution should be exercised in assigning zone of origin based on this histologic appearance, especially in limited samples such as prostate needle biopsy...
  14. pmc Prostate cancer topography and patterns of lymph node metastasis
    Yuji Tokuda
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Am J Surg Pathol 34:1862-7. 2010
    ....
  15. doi request reprint Prostatic transition zone directed needle biopsies uncommonly sample clinically relevant transition zone tumors
    Chadwick F Haarer
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    J Urol 182:1337-41. 2009
    ..We compared prostate cancer detected in transition zone directed needle biopsies with those in corresponding radical prostatectomy specimens...
  16. pmc Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cancer: recognition of the syndrome by pathologic features and the utility of detecting aberrant succination by immunohistochemistry
    Ying bei Chen
    Departments of Pathology Medicine, Genitourinary Oncology Service Department of Surgery, Urology Service Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY Department of Pharmacology, Physiology and Neuroscience, School of Medicine, University of South Carolina, Columbia, SC
    Am J Surg Pathol 38:627-37. 2014
    ....
  17. doi request reprint Carbonic anhydrase IX expression in clear cell renal cell carcinoma: an immunohistochemical study comparing 2 antibodies
    Hikmat A Al-Ahmadie
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 32:377-82. 2008
    ..Therefore, similar to the clone M75, NB100-417 can be used as a diagnostic and potentially a prognostic marker in CRCC, with the advantage of its commercial availability...
  18. doi request reprint Interobserver and intraobserver reproducibility in digital and routine microscopic assessment of prostate needle biopsies
    Paula A Rodriguez-Urrego
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Hum Pathol 42:68-74. 2011
    ....
  19. ncbi request reprint Anatomy of the anterior prostate and extraprostatic space: a contemporary surgical pathology analysis
    Samson W Fine
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Adv Anat Pathol 14:401-7. 2007
    ....
  20. pmc Urachal carcinoma: a clinicopathologic analysis of 24 cases with outcome correlation
    Anuradha Gopalan
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Am J Surg Pathol 33:659-68. 2009
    ..Detailed pathologic studies with clinical outcome correlation are few...
  21. doi request reprint The diagnostic accuracy of percutaneous renal needle core biopsy and its potential impact on the clinical management of renal cortical neoplasms
    Lan L Gellert
    From the Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York
    Arch Pathol Lab Med 138:1673-9. 2014
    ..While biopsies are now increasingly being performed for the diagnosis of renal cortical neoplasms, the influence of the rendered pathological diagnoses on the clinical management is only rarely documented...
  22. doi request reprint Pathologic features of renal cortical tumors
    Satish K Tickoo
    Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA
    Urol Clin North Am 35:551-61; v. 2008
    ..The authors believe that the recently gained knowledge about molecular-driven antigen expression will play an important role in the characterization, development, and evaluation of targeted therapies in kidney cancer in the coming years...
  23. pmc Somatic mutation of fibroblast growth factor receptor-3 (FGFR3) defines a distinct morphological subtype of high-grade urothelial carcinoma
    Hikmat A Al-Ahmadie
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA
    J Pathol 224:270-9. 2011
    ..Histological review could thus aid in the development of targeted inhibitors of FGFR-3 by facilitating the identification of the subset of patients most likely to harbour activating mutations in the FGFR3 gene...
  24. doi request reprint Testicular mixed germ cell tumors: a morphological and immunohistochemical study using stem cell markers, OCT3/4, SOX2 and GDF3, with emphasis on morphologically difficult-to-classify areas
    Anuradha Gopalan
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Mod Pathol 22:1066-74. 2009
    ..Embryonal carcinoma-like high-grade' nuclear details are the most important morphological criterion for the diagnosis of embryonal carcinoma in difficult-to-classify areas...
  25. pmc Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
    Brett S Carver
    Cancer Biology and Genetics Program, Sloan Kettering Institute, New York, New York, USA
    Nat Genet 41:619-24. 2009
    ..Thus, ERG has a distinct role in prostate cancer progression and cooperates with PTEN haploinsufficiency to promote progression of HGPIN to invasive adenocarcinoma...
  26. pmc Frequent somatic CDH1 loss-of-function mutations in plasmacytoid variant bladder cancer
    Hikmat A Al-Ahmadie
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Nat Genet 48:356-8. 2016
    ..Consistent with the aggressive clinical behavior of plasmacytoid carcinomas, which frequently recur locally, CRISPR/Cas9-mediated knockout of CDH1 in bladder cancer cells enhanced cell migration. ..
  27. ncbi request reprint Estrogen and progesterone-receptor-positive stroma as a non-tumorous proliferation in kidneys: a possible metaplastic response to obstruction
    Satish K Tickoo
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Mod Pathol 21:60-5. 2008
    ..Its association with obstructive changes suggests that it may represent a metaplastic change in the renal interstitial cells surrounding these obstructed epithelial structures...
  28. doi request reprint Hypoxia-inducible factor and mammalian target of rapamycin pathway markers in urothelial carcinoma of the bladder: possible therapeutic implications
    Satish K Tickoo
    Department of Pathology Genitourinary Oncology Service, Division of Solid Tumor Oncology, Memorial Sloan Kettering Cancer Center, Center, New York, NY, USA
    BJU Int 107:844-9. 2011
    ....
  29. pmc Stromal Hedgehog signaling maintains smooth muscle and hampers micro-invasive prostate cancer
    Zhaohui Yang
    Biochemistry, Cell and Molecular Biology Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, 10065, USA
    Dis Model Mech . 2016
    ..Our studies highlight the importance of understanding how HH signaling and stromal composition impact on PCa to optimize drug treatments...
  30. pmc Organoid cultures derived from patients with advanced prostate cancer
    Dong Gao
    Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Cell 159:176-87. 2014
    ..The methodology described here should enable the generation of a large repertoire of patient-derived prostate cancer lines amenable to genetic and pharmacologic studies. ..