Anil Shanker

Summary

Affiliation: Meharry Medical College
Country: USA

Publications

  1. pmc Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity
    Anil Shanker
    Department of Biochemistry and Cancer Biology, School of Medicine, Meharry Medical College, Nashville, Tennessee Host Tumor Interactions Research Program, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee School of Graduate Studies and Research, Meharry Medical College, Nashville, Tennessee
    Cancer Res 75:5260-72. 2015
  2. pmc Molecular signatures mostly associated with NK cells are predictive of relapse free survival in breast cancer patients
    Maria Libera Ascierto
    J Transl Med 11:145. 2013
  3. pmc Cooperativity of adaptive and innate immunity: implications for cancer therapy
    Anil Shanker
    Laboratory of Lymphocyte Function, Department of Biochemistry and Cancer Biology, School of Medicine, Meharry Medical College, Nashville, TN 37208, USA
    Cancer Immunol Immunother 60:1061-74. 2011
  4. pmc Bortezomib enhances expression of effector molecules in anti-tumor CD8+ T lymphocytes by promoting Notch-nuclear factor-κB crosstalk
    Menaka C Thounaojam
    Department of Biochemistry and Cancer Biology, School of Medicine, Meharry Medical College, Nashville, TN, USA
    Oncotarget 6:32439-55. 2015
  5. pmc Multivalent Forms of the Notch Ligand DLL-1 Enhance Antitumor T-cell Immunity in Lung Cancer and Improve Efficacy of EGFR-Targeted Therapy
    Asel K Biktasova
    Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee
    Cancer Res 75:4728-41. 2015
  6. doi request reprint Validation of research trajectory 1 of an Exposome framework: Exposure to benzo(a)pyrene confers enhanced susceptibility to bacterial infection
    Ryan S Clark
    Department of Neuroscience and Pharmacology, Meharry Medical College, Nashville, TN 37208, USA
    Environ Res 146:173-84. 2016
  7. pmc Challenges and future perspectives of T cell immunotherapy in cancer
    Maria Teresa P de Aquino
    Department of Biochemistry and Cancer Biology, School of Medicine, Meharry Medical College, Nashville, TN 37208, USA
    Immunol Lett 166:117-33. 2015
  8. pmc Common gamma chain cytokines in combinatorial immune strategies against cancer
    Stephanie R Pulliam
    Department of Biochemistry and Cancer Biology, School of Medicine, Meharry Medical College, Nashville, TN 37208, USA School of Graduate Studies and Research, Meharry Medical College, Nashville, TN 37208, USA
    Immunol Lett 169:61-72. 2016
  9. pmc NK cells: immune cross-talk and therapeutic implications
    Anshu Malhotra
    Laboratory of Lymphocyte Function, Department of Biochemistry and Cancer Biology, School of Medicine, Meharry Medical College, 2005 Harold D West Basic Sciences Building, 1005 Dr DB Todd Jr Boulevard, Nashville, TN 37208, USA
    Immunotherapy 3:1143-66. 2011

Collaborators

  • Francesco M Marincola
  • Roman V Uzhachenko
  • Anshu Malhotra
  • Stephanie R Pulliam
  • Ryan S Clark
  • Samuel T Pellom
  • Mikhail M Dikov
  • Maria Teresa P de Aquino
  • Menaka C Thounaojam
  • Duafalia F Dudimah
  • Asel K Biktasova
  • David P Carbone
  • Maria Libera Ascierto
  • Tongwen Zhang
  • Samuel E Adunyah
  • Maureen Y Lichtveld
  • Aramandla Ramesh
  • Darryl B Hood
  • Burthia Booker
  • Michael A Langston
  • Matthews Juarez Patricia
  • Paul D Juarez
  • Mark Maguire
  • Manoj K Mishra
  • Elena E Tchekneva
  • Sergey V Novitskiy
  • Jason V Evans
  • Rajeswara R Arasada
  • Anwari Akhter
  • Kyungho Park
  • Ena Wang
  • Hanif Khalak
  • Kyle K Payne
  • Harry D Bear
  • Michael O Idowu
  • Sara Tomei
  • Paolo A Ascierto
  • Yingdong Zhao
  • Davide Bedognetti
  • Masoud H Manjili
  • Xiang yang Wang
  • Andrea De Maria
  • Catherine I Dumur

Detail Information

Publications9

  1. pmc Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity
    Anil Shanker
    Department of Biochemistry and Cancer Biology, School of Medicine, Meharry Medical College, Nashville, Tennessee Host Tumor Interactions Research Program, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee School of Graduate Studies and Research, Meharry Medical College, Nashville, Tennessee
    Cancer Res 75:5260-72. 2015
    ..Our findings highlight the potential of proteasome inhibitors to enhance antitumor T-cell function in the context of cancer immunotherapy. Cancer Res; 75(24); 5260-72. ©2015 AACR. ..
  2. pmc Molecular signatures mostly associated with NK cells are predictive of relapse free survival in breast cancer patients
    Maria Libera Ascierto
    J Transl Med 11:145. 2013
    ..CONCLUSIONS: The parameters identified in this study, together with the prognostic signature previously reported by our group, highlight the cooperation between the innate and adaptive immune components within the tumor microenvironment...
  3. pmc Cooperativity of adaptive and innate immunity: implications for cancer therapy
    Anil Shanker
    Laboratory of Lymphocyte Function, Department of Biochemistry and Cancer Biology, School of Medicine, Meharry Medical College, Nashville, TN 37208, USA
    Cancer Immunol Immunother 60:1061-74. 2011
    ..Mechanistic understanding of this two-way immune cross-talk could provide insights into novel strategies for designing better immunotherapy approaches against cancer and other diseases that normally defy immune control...
  4. pmc Bortezomib enhances expression of effector molecules in anti-tumor CD8+ T lymphocytes by promoting Notch-nuclear factor-κB crosstalk
    Menaka C Thounaojam
    Department of Biochemistry and Cancer Biology, School of Medicine, Meharry Medical College, Nashville, TN, USA
    Oncotarget 6:32439-55. 2015
    ....
  5. pmc Multivalent Forms of the Notch Ligand DLL-1 Enhance Antitumor T-cell Immunity in Lung Cancer and Improve Efficacy of EGFR-Targeted Therapy
    Asel K Biktasova
    Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee
    Cancer Res 75:4728-41. 2015
    ..Our findings offer preclinical mechanistic support for the development of multivalent DLL1 to stimulate antitumor immunity...
  6. doi request reprint Validation of research trajectory 1 of an Exposome framework: Exposure to benzo(a)pyrene confers enhanced susceptibility to bacterial infection
    Ryan S Clark
    Department of Neuroscience and Pharmacology, Meharry Medical College, Nashville, TN 37208, USA
    Environ Res 146:173-84. 2016
    ..Such exposures across the lifespan would have the potential to induce immunosuppressive endophenotypes in vulnerable populations. ..
  7. pmc Challenges and future perspectives of T cell immunotherapy in cancer
    Maria Teresa P de Aquino
    Department of Biochemistry and Cancer Biology, School of Medicine, Meharry Medical College, Nashville, TN 37208, USA
    Immunol Lett 166:117-33. 2015
    ....
  8. pmc Common gamma chain cytokines in combinatorial immune strategies against cancer
    Stephanie R Pulliam
    Department of Biochemistry and Cancer Biology, School of Medicine, Meharry Medical College, Nashville, TN 37208, USA School of Graduate Studies and Research, Meharry Medical College, Nashville, TN 37208, USA
    Immunol Lett 169:61-72. 2016
    ..We will briefly cover their biological function, potential applications in cancer therapy, and update on their use in combinatorial immune strategies for eradicating tumors and hematopoietic malignancies. ..
  9. pmc NK cells: immune cross-talk and therapeutic implications
    Anshu Malhotra
    Laboratory of Lymphocyte Function, Department of Biochemistry and Cancer Biology, School of Medicine, Meharry Medical College, 2005 Harold D West Basic Sciences Building, 1005 Dr DB Todd Jr Boulevard, Nashville, TN 37208, USA
    Immunotherapy 3:1143-66. 2011
    ..While tracing the remarkable properties of NK cells and the major developments in this field, we highlight the role of immune cooperativity in the betterment of current immunotherapeutic approaches...