Michael E Widlansky

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. pmc Altered mitochondrial membrane potential, mass, and morphology in the mononuclear cells of humans with type 2 diabetes
    Michael E Widlansky
    Department of Medicine, Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Transl Res 156:15-25. 2010
  2. pmc Nitric oxide synthase-dependent vasodilation of human subcutaneous arterioles correlates with noninvasive measurements of endothelial function
    Kodlipet Dharmashankar
    Department of Medicine, Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Am J Hypertens 25:528-34. 2012
  3. pmc Adverse alterations in mitochondrial function contribute to type 2 diabetes mellitus-related endothelial dysfunction in humans
    Tinoy J Kizhakekuttu
    Department of Medicine, Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Arterioscler Thromb Vasc Biol 32:2531-9. 2012
  4. pmc Acute exposure to low glucose rapidly induces endothelial dysfunction and mitochondrial oxidative stress: role for AMP kinase
    Jingli Wang
    Department of Medicine, Division of Cardiovascular Medicine, Graduate School of Bioscience, Medical College of Wisconsin, 9200 W Wisconsin Ave, FEC Ste E5100, Milwaukee, WI 53226, USA
    Arterioscler Thromb Vasc Biol 32:712-20. 2012
  5. pmc Folic acid supplementation improves vascular function in professional dancers with endothelial dysfunction
    Anne Z Hoch
    Department of Orthopaedic Surgery Cardiovascular Center, Medical College of Wisconsin, Milwaukee, USA
    PM R 3:1005-12. 2011
  6. doi request reprint Associations of Reducing Sedentary Time With Vascular Function and Insulin Sensitivity in Older Sedentary Adults
    Tisha B Suboc
    Department of Medicine, Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Am J Hypertens 29:46-53. 2016
  7. doi request reprint Mineralocorticoid exposure and receptor activity modulate microvascular endothelial function in African Americans with and without hypertension
    Appesh Mohandas
    Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
    Vasc Med 20:401-8. 2015
  8. pmc Regulation of endothelial function by mitochondrial reactive oxygen species
    Michael E Widlansky
    Department of Medicine, Cardiovascular Medicine Division and Department of Pharmacology, Medical College of Wisconsin, Milwaukee, Wisconsin
    Antioxid Redox Signal 15:1517-30. 2011
  9. pmc Parstatin: a cryptic peptide involved in cardioprotection after ischaemia and reperfusion injury
    Jennifer L Strande
    Division of Cardiovascular Medicine, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, USA
    Cardiovasc Res 83:325-34. 2009
  10. ncbi request reprint Lifestyle choices and endothelial function: risk and relevance
    Jingli Wang
    Department of Medicine, Cardiovascular Division, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Curr Vasc Pharmacol 7:209-24. 2009

Collaborators

Detail Information

Publications16

  1. pmc Altered mitochondrial membrane potential, mass, and morphology in the mononuclear cells of humans with type 2 diabetes
    Michael E Widlansky
    Department of Medicine, Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Transl Res 156:15-25. 2010
    ..Furthermore, potentially clinically relevant perturbations in mitochondrial homeostasis in T2DM human mononuclear cells can be detected...
  2. pmc Nitric oxide synthase-dependent vasodilation of human subcutaneous arterioles correlates with noninvasive measurements of endothelial function
    Kodlipet Dharmashankar
    Department of Medicine, Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Am J Hypertens 25:528-34. 2012
    ..Limited data relating subcutaneous arteriolar endothelial function, cardiovascular risk factors, and noninvasive measurements of endothelial function currently exist...
  3. pmc Adverse alterations in mitochondrial function contribute to type 2 diabetes mellitus-related endothelial dysfunction in humans
    Tinoy J Kizhakekuttu
    Department of Medicine, Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Arterioscler Thromb Vasc Biol 32:2531-9. 2012
    ..Mitochondrial dysfunction plays a key pathophysiological role in type 2 diabetes mellitus (T2DM). Data delineating relationships between mitochondrial and endothelial dysfunction in humans with T2DM are lacking...
  4. pmc Acute exposure to low glucose rapidly induces endothelial dysfunction and mitochondrial oxidative stress: role for AMP kinase
    Jingli Wang
    Department of Medicine, Division of Cardiovascular Medicine, Graduate School of Bioscience, Medical College of Wisconsin, 9200 W Wisconsin Ave, FEC Ste E5100, Milwaukee, WI 53226, USA
    Arterioscler Thromb Vasc Biol 32:712-20. 2012
    ..The reasons for this remain unclear, and the effects of low glucose exposure on vascular endothelial function remain largely unknown. We endeavored to determine the effects of low glucose on endothelial cells and intact human arterioles...
  5. pmc Folic acid supplementation improves vascular function in professional dancers with endothelial dysfunction
    Anne Z Hoch
    Department of Orthopaedic Surgery Cardiovascular Center, Medical College of Wisconsin, Milwaukee, USA
    PM R 3:1005-12. 2011
    ..To determine if folic acid supplementation improves vascular function (brachial artery flow-mediated dilation [FMD]) in professional dancers with known endothelial dysfunction...
  6. doi request reprint Associations of Reducing Sedentary Time With Vascular Function and Insulin Sensitivity in Older Sedentary Adults
    Tisha B Suboc
    Department of Medicine, Division of Cardiovascular Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Am J Hypertens 29:46-53. 2016
    ..Whether reductions in sedentary time alone contribute to this improvement is unknown...
  7. doi request reprint Mineralocorticoid exposure and receptor activity modulate microvascular endothelial function in African Americans with and without hypertension
    Appesh Mohandas
    Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
    Vasc Med 20:401-8. 2015
    ..Aldosterone-related endothelial dysfunction may be responsible for at least a portion of the greater blood pressure sensitivity to aldosterone in African Americans. This may be in part related to vascular suppression of G6PD activity. ..
  8. pmc Regulation of endothelial function by mitochondrial reactive oxygen species
    Michael E Widlansky
    Department of Medicine, Cardiovascular Medicine Division and Department of Pharmacology, Medical College of Wisconsin, Milwaukee, Wisconsin
    Antioxid Redox Signal 15:1517-30. 2011
    ..Future potential avenues of research in this field also are discussed...
  9. pmc Parstatin: a cryptic peptide involved in cardioprotection after ischaemia and reperfusion injury
    Jennifer L Strande
    Division of Cardiovascular Medicine, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, USA
    Cardiovasc Res 83:325-34. 2009
    ..Although much research has focused on the activated receptor, little is known about the 41-amino acid N-terminal peptide (parstatin). We hypothesized that parstatin would protect the heart against ischaemia-reperfusion injury...
  10. ncbi request reprint Lifestyle choices and endothelial function: risk and relevance
    Jingli Wang
    Department of Medicine, Cardiovascular Division, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Curr Vasc Pharmacol 7:209-24. 2009
    ....
  11. pmc Impaired endothelial function in preadolescent children with type 1 diabetes
    Ghufran S Babar
    Department of Pediatric Endocrinology, Children s Mercy Hospital, Kansas City, Missouri, USA
    Diabetes Care 34:681-5. 2011
    ....
  12. pmc Relative importance of step count, intensity, and duration on physical activity's impact on vascular structure and function in previously sedentary older adults
    Tisha B Suboc
    Division of Cardiovascular Medicine, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI
    J Am Heart Assoc 3:e000702. 2014
    ..Many groups have encouraged goals of ≥10 000 steps/day or ≥30 min/day of moderate intensity physical activity (MPA) to reduce age-related CV risk. The impact of MPA on the vasculature of older adults remains unclear...
  13. pmc Association between the female athlete triad and endothelial dysfunction in dancers
    Anne Z Hoch
    Department of Orthopaedic Surgery, Medical College of Wisconsin, 9200 West Wisconsin Ave, Milwaukee, WI 43226, USA
    Clin J Sport Med 21:119-25. 2011
    ....
  14. pmc Measuring FMD in the brachial artery: how important is QRS gating?
    Tinoy J Kizhakekuttu
    Cardiovascular Medicine Division, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    J Appl Physiol (1985) 109:959-65. 2010
    ..This finding may allow for simplification of FMD measurement and aid in the development of FMD as a potentially useful clinical tool...
  15. pmc Natural antioxidants and hypertension: promise and challenges
    Tinoy J Kizhakekuttu
    Department of Medicine, Cardiovascular Medicine Division and Department of Pharmacology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Cardiovasc Ther 28:e20-32. 2010
    ..This review focuses on recent literature evaluating naturally occurring antioxidants with respect to their impact on hypertension...