Michael Olivier

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. pmc Quantitative comparison of lipoprotein fractions derived from human plasma and serum by liquid chromatography-tandem mass spectrometry
    Lisamarie A Collins
    Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, WI, USA
    Proteome Sci 8:42. 2010
  2. pmc Single nucleotide polymorphisms in protein tyrosine phosphatase 1beta (PTPN1) are associated with essential hypertension and obesity
    Michael Olivier
    Stanford Human Genome Center, Stanford University School of Medicine, CA, USA
    Hum Mol Genet 13:1885-92. 2004
  3. ncbi request reprint Complex high-resolution linkage disequilibrium and haplotype patterns of single-nucleotide polymorphisms in 2.5 Mb of sequence on human chromosome 21
    M Olivier
    Stanford Human Genome Center, Department of Genetics, Stanford University School of Medicine, Palo Alto, California 94304, USA
    Genomics 78:64-72. 2001
  4. pmc High-throughput genotyping of single nucleotide polymorphisms using new biplex invader technology
    Michael Olivier
    Stanford Human Genome Center, Stanford University School of Medicine, 975 California Avenue, Palo Alto, CA 94305, USA
    Nucleic Acids Res 30:e53. 2002
  5. pmc Haplotype analysis of the apolipoprotein gene cluster on human chromosome 11
    Michael Olivier
    Human and Molecular Genetics Center, Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Genomics 83:912-23. 2004
  6. pmc Obesity-related dyslipidemia associated with FAAH, independent of insulin response, in multigenerational families of Northern European descent
    Yi Zhang
    Medical College of Wisconsin, Milwaukee, Wisconsin, WI 53226, USA
    Pharmacogenomics 10:1929-39. 2009
  7. pmc A comprehensive analysis of adiponectin QTLs using SNP association, SNP cis-effects on peripheral blood gene expression and gene expression correlation identified novel metabolic syndrome (MetS) genes with potential role in carcinogenesis and systemic inf
    Yi Zhang
    TOPS Obesity and Metabolic Research Center, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    BMC Med Genomics 6:14. 2013
  8. pmc A novel procedure for genotyping of single nucleotide polymorphisms in trisomy with genomic DNA and the invader assay
    Kelly J Duffy
    Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI, USA
    Nucleic Acids Res 36:e145. 2008
  9. doi request reprint Genetic variation in the peroxisome proliferator activated receptor-gamma gene is associated with histologically advanced NAFLD
    Samer Gawrieh
    Division of Gastroenterology and Hepatology, Department of Medicine, Medical College of Wisconsin, 9200 W Wisconsin Ave, Milwaukee, WI 53212, USA
    Dig Dis Sci 57:952-7. 2012
  10. pmc Analysis of concordance of different haplotype block partitioning algorithms
    Amit R Indap
    Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, USA
    BMC Bioinformatics 6:303. 2005

Research Grants

Collaborators

Detail Information

Publications48

  1. pmc Quantitative comparison of lipoprotein fractions derived from human plasma and serum by liquid chromatography-tandem mass spectrometry
    Lisamarie A Collins
    Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, WI, USA
    Proteome Sci 8:42. 2010
    ..After delipidating these samples, we performed a quantitative proteomic analysis to compare the lipoprotein-associated proteins derived from both plasma and serum...
  2. pmc Single nucleotide polymorphisms in protein tyrosine phosphatase 1beta (PTPN1) are associated with essential hypertension and obesity
    Michael Olivier
    Stanford Human Genome Center, Stanford University School of Medicine, CA, USA
    Hum Mol Genet 13:1885-92. 2004
    ..Given similar associations found in other populations to insulin resistance and diabetes, this gene may play a crucial role in the development of the characteristic metabolic changes seen in patients with the metabolic syndrome...
  3. ncbi request reprint Complex high-resolution linkage disequilibrium and haplotype patterns of single-nucleotide polymorphisms in 2.5 Mb of sequence on human chromosome 21
    M Olivier
    Stanford Human Genome Center, Department of Genetics, Stanford University School of Medicine, Palo Alto, California 94304, USA
    Genomics 78:64-72. 2001
    ....
  4. pmc High-throughput genotyping of single nucleotide polymorphisms using new biplex invader technology
    Michael Olivier
    Stanford Human Genome Center, Stanford University School of Medicine, 975 California Avenue, Palo Alto, CA 94305, USA
    Nucleic Acids Res 30:e53. 2002
    ..The biplex invader assay with its automated set-up and analysis offers a new efficient high-throughput genotyping platform that is suitable for association studies in large study cohorts...
  5. pmc Haplotype analysis of the apolipoprotein gene cluster on human chromosome 11
    Michael Olivier
    Human and Molecular Genetics Center, Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Genomics 83:912-23. 2004
    ..These results highlight the complex genetic relationship between APOA5 and APOC3 and support the notion that APOA5 represents an independent risk gene affecting plasma triglyceride concentrations in humans...
  6. pmc Obesity-related dyslipidemia associated with FAAH, independent of insulin response, in multigenerational families of Northern European descent
    Yi Zhang
    Medical College of Wisconsin, Milwaukee, Wisconsin, WI 53226, USA
    Pharmacogenomics 10:1929-39. 2009
    ..In recent years, there has been tremendous interest in understanding the endocannabinoid system as a novel therapeutic target for the treatment of obesity-related dyslipidemia...
  7. pmc A comprehensive analysis of adiponectin QTLs using SNP association, SNP cis-effects on peripheral blood gene expression and gene expression correlation identified novel metabolic syndrome (MetS) genes with potential role in carcinogenesis and systemic inf
    Yi Zhang
    TOPS Obesity and Metabolic Research Center, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    BMC Med Genomics 6:14. 2013
    ..We previously performed microsatellite linkage analyses using adiponectin as a surrogate marker and revealed two QTLs on chr5 (5p14) and chr14 (14q13)...
  8. pmc A novel procedure for genotyping of single nucleotide polymorphisms in trisomy with genomic DNA and the invader assay
    Kelly J Duffy
    Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI, USA
    Nucleic Acids Res 36:e145. 2008
    ....
  9. doi request reprint Genetic variation in the peroxisome proliferator activated receptor-gamma gene is associated with histologically advanced NAFLD
    Samer Gawrieh
    Division of Gastroenterology and Hepatology, Department of Medicine, Medical College of Wisconsin, 9200 W Wisconsin Ave, Milwaukee, WI 53212, USA
    Dig Dis Sci 57:952-7. 2012
    ....
  10. pmc Analysis of concordance of different haplotype block partitioning algorithms
    Amit R Indap
    Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, USA
    BMC Bioinformatics 6:303. 2005
    ....
  11. pmc Fatty acid binding protein 3 (fabp3) is associated with insulin, lipids and cardiovascular phenotypes of the metabolic syndrome through epigenetic modifications in a Northern European family population
    Yi Zhang
    TOPS Obesity and Metabolic Research Center, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    BMC Med Genomics 6:9. 2013
    ..The objective of this study was to test the hypothesis that CpG methylation status of a key regulator of lipid homeostasis, FABP3, is a quantitative trait associated with status of MetS phenotypes in humans...
  12. pmc Genetic variation in cannabinoid receptor 1 (CNR1) is associated with derangements in lipid homeostasis, independent of body mass index
    Tes M Baye
    Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Pharmacogenomics 9:1647-56. 2008
    ..We therefore tested the hypothesis that genetic variation in CNR1 is associated with common obesity-related metabolic disorders...
  13. pmc Genetic linkage and association of the growth hormone secretagogue receptor (ghrelin receptor) gene in human obesity
    Andrea Baessler
    Department of Physiology, Human and Molecular Genetics Center, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    Diabetes 54:259-67. 2005
    ....
  14. pmc 18O labeling over a coffee break: a rapid strategy for quantitative proteomics
    Shama P Mirza
    National Center for Proteomics Research, Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    J Proteome Res 7:3042-8. 2008
    ..We demonstrate the efficiency and accuracy of the method using a four protein mixture and whole cell lysate from rat vascular endothelial cells...
  15. doi request reprint Putting the Invader assay to work: laboratory application and data management
    Yi Zhang
    Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, WI, USA
    Methods Mol Biol 578:363-77. 2009
    ..Here, from an end-user point of view, we discuss how a commercially available genotyping platform, the Invader assay, can be utilized to meet the needs and demands of human genomic research in a laboratory...
  16. pmc Automated SNP genotype clustering algorithm to improve data completeness in high-throughput SNP genotyping datasets from custom arrays
    Edward M Smith
    Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Genomics Proteomics Bioinformatics 5:256-9. 2007
    ..This analysis suggests that the use of multiple genotype calling algorithms may be advisable in high-throughput SNP genotyping experiments. The software is written in Perl and is available from the corresponding author...
  17. pmc ZoomQuant: an application for the quantitation of stable isotope labeled peptides
    Brian D Halligan
    Bioinformatics, Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53213, USA
    J Am Soc Mass Spectrom 16:302-6. 2005
    ..Finally, ZoomQuant generates a summary report of the relative abundance of the peptides identified in the two samples...
  18. ncbi request reprint Insights into Dahl salt-sensitive hypertension revealed by temporal patterns of renal medullary gene expression
    Mingyu Liang
    Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Physiol Genomics 12:229-37. 2003
    ....
  19. pmc Association of TMTC2 With Human Nonsyndromic Sensorineural Hearing Loss
    Christina L Runge
    Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee
    JAMA Otolaryngol Head Neck Surg 142:866-72. 2016
    ..It is likely that other genes and mutations also cause SNHL...
  20. pmc Relative quantification of peptide phosphorylation in a complex mixture using 18O labeling
    Julia R Smith
    Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Physiol Genomics 31:357-63. 2007
    ....
  21. pmc Integrated approach for the comprehensive characterization of lipoproteins from human plasma using FPLC and nano-HPLC-tandem mass spectrometry
    Lisamarie A Collins
    Biotechnology and Bioengineering Center, Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Physiol Genomics 40:208-15. 2010
    ....
  22. pmc Methods and approaches for the comprehensive characterization and quantification of cellular proteomes using mass spectrometry
    Shama P Mirza
    National Center for Proteomics Research, Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA E mail
    Physiol Genomics 33:3-11. 2008
    ....
  23. pmc The Invader assay for SNP genotyping
    Michael Olivier
    Human and Molecular Genetics Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Mutat Res 573:103-10. 2005
    ....
  24. pmc Quantitative characterization of changes in the cardiac mitochondrial proteome during anesthetic preconditioning and ischemia
    Martin Bienengraeber
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Physiol Genomics 45:163-70. 2013
    ..Thus, a proteomic mass spectral approach does not only assess quantitative changes without prior knowledge of proteins, but also allows insight into the mechanisms of ischemia and reperfusion injury and APC...
  25. pmc Sequential abundant ion fragmentation analysis (SAIFA): an alternative approach for phosphopeptide identification using an ion trap mass spectrometer
    Marla Chesnik
    Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Anal Biochem 418:197-203. 2011
    ..To the best of our knowledge, this is the first report to use SAIFA for phosphopeptide identification...
  26. pmc Genetic determinants of obesity-related lipid traits
    Gabriele E Sonnenberg
    Division of Endocrinology, Metabolism and Clinical Nutrition, Department of Medicine and Human Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI, USA
    J Lipid Res 45:610-5. 2004
    ..These newly identified loci likely harbor genetic elements that influence traits underlying lipid adversities associated with obesity...
  27. pmc Improved method for the analysis of membrane proteins by mass spectrometry
    Shama P Mirza
    National Center for Proteomics Research, Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Physiol Genomics 30:89-94. 2007
    ..Comparison of our results to results obtained by direct tryptic digestion of insoluble membrane pellets identifies an increased number of membrane proteins, and a higher quality of the resulting mass spectral data...
  28. pmc Linkage and segregation analysis of black and brindle coat color in domestic dogs
    Julie A Kerns
    Department of Genetics, Stanford University, Stanford, California 94035, USA
    Genetics 176:1679-89. 2007
    ..These findings suggest a molecular model for a new component of the melanocortin signaling pathway and reveal how coat-color patterns and pigmentary diversity have been shaped by recent selection...
  29. doi request reprint Hepatic gene networks in morbidly obese patients with nonalcoholic fatty liver disease
    Samer Gawrieh
    Department of Medicine, Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, WI 53212, USA
    Obes Surg 20:1698-709. 2010
    ..Genetic factors alter the risk for nonalcoholic fatty liver disease (NAFLD). We sought to identify NAFLD-associated genes and elucidate gene networks and pathways involved in the pathogenesis of NAFLD...
  30. ncbi request reprint Radiation hybrid mapping with BAC ends
    Michael Olivier
    Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, USA
    Methods Mol Biol 255:163-9. 2004
  31. ncbi request reprint Gene expression reveals vulnerability to oxidative stress and interstitial fibrosis of renal outer medulla to nonhypertensive elevations of ANG II
    Baozhi Yuan
    Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Am J Physiol Regul Integr Comp Physiol 284:R1219-30. 2003
    ....
  32. pmc Comparison of linkage disequilibrium patterns between the HapMap CEPH samples and a family-based cohort of Northern European descent
    E M Smith
    Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Genomics 88:407-14. 2006
    ..8 in the disease cohort. This confirms the usefulness of the CEPH cohort of the HapMap as a reference sample for further investigations into the genomic variation of populations of Northern European descent...
  33. ncbi request reprint A high-resolution radiation hybrid map of the human genome draft sequence
    M Olivier
    Stanford Human Genome Center, Stanford University School of Medicine, 975 California Avenue, Palo Alto, CA 94304, USA
    Science 291:1298-302. 2001
    ..The TNG map order was identical to one of the two sequence orders in 60% of these discrepant cases...
  34. pmc Current analysis platforms and methods for detecting copy number variation
    Wenli Li
    Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Physiol Genomics 45:1-16. 2013
    ..In this article, we evaluate a suite of commonly used and recently developed approaches to uncovering genome-wide CNVs and discuss the relative merits of each...
  35. pmc Obesity and its therapy: from genes to community action
    Joseph A Skelton
    Division of Pediatric Gastroenterology and Nutrition, Medical College of Wisconsin, 8701 Watertown Plank Road, PO Box 26509, Milwaukee, WI 53226, USA
    Pediatr Clin North Am 53:777-94. 2006
    ..Many of these behaviors are being evaluated in animal models and hold great promise for targeted interventions in the future...
  36. pmc Simultaneous quantification and identification using 18O labeling with an ion trap mass spectrometer and the analysis software application "ZoomQuant"
    Wayne A Hicks
    National Proteomics Research Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53213, USA
    J Am Soc Mass Spectrom 16:916-25. 2005
    ..This compares well with data produced from (18)O labeling experiments using time of flight (TOF) and Fourier transform-ion cyclotron resonance (FT-ICR) MS instruments...
  37. ncbi request reprint The glycine allele of a glycine/arginine polymorphism in the beta2-adrenergic receptor gene is associated with essential hypertension in a population of Chinese origin
    K Ranade
    Department of Genetics, Stanford University School of Medicine, California, USA
    Am J Hypertens 14:1196-200. 2001
    ..We sought to replicate these results in a population of Chinese origin primarily from Taiwan and the San Francisco Bay area...
  38. pmc INSIG1 influences obesity-related hypertriglyceridemia in humans
    E M Smith
    Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI, USA
    J Lipid Res 51:701-8. 2010
    ..00117). The variant rs2721 alone explains 5.4% of the observed linkage in our cohort, suggesting that additional, yet-undiscovered genes and sequence variants in the QTL interval also contribute to alterations in TG levels in humans...
  39. pmc Serotonin (5-HT) receptor 5A sequence variants affect human plasma triglyceride levels
    Y Zhang
    Human and Molecular Genetics Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Physiol Genomics 42:168-76. 2010
    ..This suggests a potential brain-specific regulation of plasma TG levels, possibly by alteration of the expression of HTR5A...
  40. pmc High-throughput genotyping with single nucleotide polymorphisms
    K Ranade
    Department of Genetics, Stanford University School of Medicine, Stanford, California 94305 5120, USA
    Genome Res 11:1262-8. 2001
    ..Indeed, large-scale genotyping has been accomplished for 23 other SNPs in 13 different genes using this method. In addition, we identified three "pseudo-SNPs" (WIAF1161, WIAF2566, and WIAF335) that are probably a result of duplication...
  41. ncbi request reprint Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides
    Philippa J Talmud
    Division of Cardiovascular Genetics, Department of Medicine, British Heart Foundation Laboratories, Rayne Building, Royal Free and University College Medical School, 5 University Street, London WC1E 6JJ, UK
    Hum Mol Genet 11:3039-46. 2002
    ..The molecular mechanisms for these effects remain to be determined...
  42. ncbi request reprint From SNPs to function: the effect of sequence variation on gene expression. Focus on "a survey of genetic and epigenetic variation affecting human gene expression"
    Michael Olivier
    Physiol Genomics 16:182-3. 2004
  43. ncbi request reprint A haplotype map of the human genome
    Michael Olivier
    Physiol Genomics 13:3-9. 2003
  44. pmc Linkage and association between distinct variants of the APOA1/C3/A4/A5 gene cluster and familial combined hyperlipidemia
    Sophie Eichenbaum-Voline
    Genomic and Molecular Medicine Group, Medical Research Council Clinical Sciences Centre, Hammersmith Hospital, London, UK
    Arterioscler Thromb Vasc Biol 24:167-74. 2004
    ....
  45. ncbi request reprint Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels
    Len A Pennacchio
    Genome Sciences Department, MS 84 171, Lawrence Berkeley National Laboratory, One Cyclotron Road, Berkeley, CA 94720, USA
    Hum Mol Genet 11:3031-8. 2002
    ..Together, the APOA5*2 and APOA5*3 haplotypes are found in 25-50% of African-Americans, Hispanics and Caucasians and support the contribution of common human variation to quantitative phenotypes in the general population...
  46. ncbi request reprint Parallel single nucleotide polymorphism genotyping by surface invasive cleavage with universal detection
    Yan Chen
    Department of Chemistry, University of Wisconsin Madison, 1101 University Avenue, Madison, Wisconsin 53706, USA
    Anal Chem 77:2400-5. 2005
    ....
  47. pmc Characterization of vascular endothelial growth factor receptors on the endothelial cell surface during hypoxia using whole cell binding arrays
    Ji Eun Lee
    Department of Chemistry, University of Wisconsin Madison, Madison, WI 53706, USA
    Anal Biochem 369:241-7. 2007
    ..This result implicates the dysregulation of VEGF receptor expression levels on the endothelial cell surface as a key factor in impaired angiogenesis...
  48. pmc Tree-structured supervised learning and the genetics of hypertension
    Jing Huang
    Affymetrix Inc, 3380 Central Expressway, Santa Clara, CA 95051, USA
    Proc Natl Acad Sci U S A 101:10529-34. 2004
    ..FlexTree and Logic Regression appear better than the others in terms of Bayes risk. However, the differences are not significant in the usual statistical sense...

Research Grants1

  1. Genomic dissection of a QTL affecting the lipid profile
    Michael Olivier; Fiscal Year: 2007
    ..abstract_text> ..