Affiliation: Medical College of Wisconsin
- A widening perspective regarding the relationship between anti-epiligrin cicatricial pemphigoid and cancerElke Sadler
Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
J Dermatol Sci 47:1-7. 2007..In addition we provide a review of the biology of laminin 5 and its potential role in cancer development...
- A synthetic superoxide dismutase/catalase mimetic EUK-207 mitigates radiation dermatitis and promotes wound healing in irradiated rat skinSusan R Doctrow
Department of Medicine, Boston University School of Medicine, Boston, MA, USA
J Invest Dermatol 133:1088-96. 2013..These results demonstrate that oxidative stress has a critical role in the progression of radiation-induced skin injury, and that the injury can be mitigated by appropriate antioxidant compounds administered 48 hours after exposure...
- Comparative analysis of methods for detection of anti-laminin 5 autoantibodies in patients with anti-epiligrin cicatricial pemphigoidZelmira Lazarova
Department of Dermatology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226 4801, USA
J Am Acad Dermatol 51:886-92. 2004..Anti-epiligrin cicatricial pemphigoid (AECP) is a subepidermal blistering disease characterized by circulating anti-basement membrane autoantibodies to laminin 5...
- Salen Mn complexes mitigate radiation injury in normal tissuesRosalind A Rosenthal
Pulmonary Center, Department of Medicine, Boston University School of Medicine, MA, USA
Anticancer Agents Med Chem 11:359-72. 2011..Optimization of their mode of delivery and other key pharmaceutical properties, and increasing understanding of their mechanism(s) of action as radiation mitigators, are key issues for future study...
- IgG anti-laminin-332 autoantibodies are present in a subset of patients with mucous membrane, but not bullous, pemphigoidZelmira Lazarova
Department of Dermatology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
J Am Acad Dermatol 58:951-8. 2008....
- Pemphigus vulgaris presenting in a radiation portalAmber C Robbins
Department of Dermatology, Medical College of Wisconsin, Milwaukee, USA
J Am Acad Dermatol 56:S82-5. 2007..This case provides support for the Dsg compensation hypothesis and may also suggest a mechanism by which irradiation may induce skin lesions...
- Transient anti-CD40L co-stimulation blockade prevents immune responses against human bullous pemphigoid antigen 2: implications for gene therapyChristoph M Lanschuetzer
Department of Dermatology, Medical College of Wisconsin, Milwaukee, Wisconcin, USA
J Invest Dermatol 129:1203-7. 2009....
- Role of intramolecular epitope spreading in pemphigus vulgarisValerie K Salato
Department of Dermatology, MFRC 4001, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
Clin Immunol 116:54-64. 2005..During disease transition, this mechanism dictates the development of Dsg3 autoantibodies that recognize human skin and lead to expression of cutaneous PV lesions...
- Expression of CD200 on epithelial cells of the murine hair follicle: a role in tissue-specific immune tolerance?Michael D Rosenblum
Department of Pediatrics, Medical College of Wisonsin, Milwaukee, Wisconsin, USA
J Invest Dermatol 123:880-7. 2004..Collectively, these results suggest that the expression of CD200 in follicular epithelium attenuates inflammatory reactions and may play a role in maintaining immune tolerance to HF-associated autoantigens...
- Increased arginase activity and endothelial dysfunction in human inflammatory bowel diseaseScott Horowitz
Dept of Medicine, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
Am J Physiol Gastrointest Liver Physiol 292:G1323-36. 2007..Loss of .NO production in IBD microvessels is linked to enhanced levels of AR in intestinal endothelial cells exposed to chronic inflammation in vivo...
- Anti-epiligrin cicatricial pemphigoid: clinical findings, immunopathogenesis, and significant associationsConleth A Egan
Dermatology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
Medicine (Baltimore) 82:177-86. 2003..AECP patients also demonstrate a significant risk for mortality as a consequence of treatment with systemic immunosuppressives. The current longitudinal study suggests that only a minority of AECP patients go into remission...
- IgG autoantibodies to type VII collagen and an exclusive IgG3 reactivity to the laminin alpha3 chain in a patient with an autoimmune subepidermal blistering diseaseAdrian Baican
Department of Dermatology, University of Medicine and Pharmacy Cluj Napoca, Cluj Napoca, Romania
J Am Acad Dermatol 53:517-22. 2005..We report a most unusual case of an autoimmune subepidermal blistering with an exclusive IgG3 reactivity to laminin 5...
- Orf-induced immunobullous disease: A distinct autoimmune blistering disorderKevin P White
Department of Dermatology and Dermatopathology, Oregon Health and Science University, Portland, Oregon 97239, USA
J Am Acad Dermatol 58:49-55. 2008..Rare associations with papulovesicular eruptions, including a bullous pemphigoid-like eruption, have also been described...