Genomes and Genes
Medical University of South Carolina
Organization: Medical University of South Carolina
- A rapid and versatile PCR-based site-directed mutagenesis protocol for generation of mutations along the entire length of a cloned cDNAVincent Dammai
Hollings Cancer Center and Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, USA
Methods Mol Biol 634:111-26. 2010..Here, HIF1alpha and HIF2alpha are used as examples to demonstrate the simplicity, speed, and versatility of the PCR-based mutagenesis method...
- Lifetime exposure to trichloroethylene (TCE) does not accelerate autoimmune disease in MRL +/+ miceMargie M Peden-Adams
Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina 29412, USA
J Environ Sci Health A Tox Hazard Subst Environ Eng 43:1402-9. 2008....
- Prenatal choline supplementation increases sensitivity to contextual processing of temporal informationCatalin V Buhusi
Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29464, USA
Brain Res 1237:204-13. 2008..Overall, these data support the view that prenatal choline availability affects the sensitivity to the context in which gaps are inserted in the to-be-timed signal, thereby influencing whether rats run, stop, or reset their clocks...
- [Multisystemic therapy with substance using adolescents: a clinical and research overview]Ashli J Sheidow
Family Services Research Center, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425, USA
Prax Kinderpsychol Kinderpsychiatr 57:401-19. 2008..g., detention, incarceration, or residential treatment facility). Based on an extensive body of controlled clinical research, MST has been identified as an effective treatment of youth antisocial behavior, including substance abuse...
- Improving acceptance of naltrexone in community addiction treatment centers: a pilot studySuzanne E Thomas
Center for Drug and Alcohol Programs, Charleston Alcohol Research Center, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
J Subst Abuse Treat 35:260-8. 2008..This study is the first reported attempt to develop and test an intervention specifically to improve acceptance of adjunctive medications for alcoholism among nonmedical addiction professionals...
- Comparison of the Infiniti vision and the series 20,000 Legacy systemsLuis E Fernández de Castro
Magill Research Center for Vision Correction, Storm Eye Institute, Medical University of South Carolina, Charleston, SC 29425, USA
Ophthalmologica 222:96-9. 2008..To compare the efficiency of the Infiniti vision system and the Series 20,000 Legacy system phacoemulsification units during routine cataract extraction...
- Metabolic complications of obstructive sleep apnea syndromeQanta A Ahmed
Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Medical University of South Carolina, Charleston 29425, USA
Am J Med Sci 335:60-4. 2008..These events fracture sleep integrity resulting in chronic partial sleep deprivation with destructive metabolic sequelae, the focus of this review...
- Achievable benchmarks of care for primary care quality indicators in a practice-based research networkAndrea M Wessell
South Carolina College of Pharmacy, Medical University of South Carolina Campus, Charleston, South Carolina 29425, USA
Am J Med Qual 23:39-46. 2008..Primary care practices can achieve high performance across a number of quality indicators, and PPRNet ABCs can serve as benchmarks for primary care practitioners and payers...
- Cognitive-behavioral stress management for individuals with substance use disorders: a pilot studySudie E Back
Division of Clinical Neuroscience, Medical University of South Carolina, Charleston, South Carolina 29425, USA
J Nerv Ment Dis 195:662-8. 2007..Although preliminary, the findings suggest that systematic investigation of interventions specifically targeting stress management in individuals with substance use disorders should be undertaken...
- Renal transplantation in high-risk patientsNicole A Weimert
Department of Pharmacy Services, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Drugs 67:1603-27. 2007..Induction and maintenance immunosuppression choices are different for high-risk patients and must be made to ensure optimal immunosuppression, while limiting patient and allograft toxicity...
- Changes in interocular axial length after pediatric cataract surgeryRupal H Trivedi
Miles Center for Pediatric Ophthalmology, Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina, Charleston, SC 29425 5536, USA
J AAPOS 11:225-9. 2007..To explore the hypothesis that preoperative interocular axial length difference changes after pediatric cataract intraocular lens implantation surgery to meet the measurement of the fellow eye...
- Impact of lung transplantation on site of death in cystic fibrosisDee Ford
Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA
J Cyst Fibros 6:391-5. 2007..Cystic fibrosis (CF) remains a lethal condition where a palliative approach is often taken at the end of life. We wanted to evaluate how lung transplantation impacts end of life care in adult CF patients...
- Characterization of renin-angiotensin system enzyme activities in cultured mouse podocytesJuan Carlos Q Velez
Department of Research, Ralph H Johnson Veterans Affairs Medical Center, Charleston, South Carolina, USA
Am J Physiol Renal Physiol 293:F398-407. 2007..These findings may reflect a specific role of POD in maintenance of intraglomerular renin-angiotensin system balance...
- Electrophysiologic correlates of intensity discrimination in cortical evoked potentials of younger and older adultsKelly C Harris
Medical University of South Carolina, Department of Otolarnygology Head and Neck Surgery, 135 Rutledge Avenue, P O Box 250550, Charleston, SC 29425, United States
Hear Res 228:58-68. 2007....
- Frequency and severity of the symptoms of irritable bowel syndrome across the anxiety disorders and depressionDaniel F Gros
Mental Health Service, Ralph H Johnson Veterans Administration Medical Center, Charleston, SC, United States
J Anxiety Disord 23:290-6. 2009..Together, these findings emphasize the role physiological symptoms of anxiety and worry in the co-occurrence of the anxiety disorders and IBS...
- Factors influencing physician referrals of patients to clinical trialsArch G Mainous
Departments of Family Medicine, Medical University of South Carolina, Charleston, SC 29425, USA
J Natl Med Assoc 100:1298-303. 2008..Our purpose was to assess physicians' attitudes and beliefs about patient recruitment, particularly minorities, into clinical trials...
- Trauma-related risk factors for substance abuse among male versus female young adultsCarla Kmett Danielson
National Crime Victims Research and Treatment Center, Medical University of South Carolina, Charleston, SC 29425, United States
Addict Behav 34:395-9. 2009..In the full sample, 29.1% met criteria for substance abuse. Trauma-related risk factors for alcohol and drug abuse differed for men and women. Clinical implications of these results are discussed...
- Fatal copper deficiency from excessive use of zinc-based denture adhesiveLawrence B Afrin
Medical University of South Carolina, Charleston, 29425, USA
Am J Med Sci 340:164-8. 2010....
- Extinction of drug cue reactivity in methamphetamine-dependent individualsKimber L Price
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, 29425, USA
Behav Res Ther 48:860-5. 2010..These results indicate that extinction of drug cue conditioned responding occurs in methamphetamine-dependent individuals, offering promise for the development of extinction- based treatment strategies...
- Impact of elevated per cent carbohydrate-deficient transferrin at hospital admission on outcomes in trauma patientsBrian P McKinzie
South Carolina College of Pharmacy Residency Program, Department of Pharmacy Services, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Am Surg 76:492-6. 2010..0052) and ventilator days (2 vs. 1.5 days, P = 0.0286). Complications and hospital charges were similar between groups. Trauma patients presenting to the ETU with %CDT elevations appear to be at risk for longer ICU and hospital LOS...
- Alternative placements for women wearing pedometersCatherine G Ling
College of Nursing, Medical University of South Carolina, Charleston, South Carolina, USA
J Am Acad Nurse Pract 22:264-9. 2010..The purpose of this pilot study was to determine if pedometer placement sites in women, other than the waist, provide the same results...
- Longitudinal differences in glycemic control by race/ethnicity among veterans with type 2 diabetesLeonard E Egede
Center for Disease Prevention and Health Interventions for Diverse Populations, Ralph H Johnson Veterans Affairs Medical Center, Charleston, SC, USA
Med Care 48:527-33. 2010..To examine longitudinal differences in glycemic control between non-Hispanic white and non-Hispanic black veterans with type 2 diabetes...
- Increasing incidence of kidney stones in children evaluated in the emergency departmentDavid J Sas
Division of Pediatric Nephrology, Medical University of South Carolina Children s Hospital, Charleston, SC 29425 6080, USA
J Pediatr 157:132-7. 2010..To test the hypothesis that there is an increase in the incidence of childhood nephrolithiasis in the state of South Carolina...
- Aripiprazole: a drug with a novel mechanism of action and possible efficacy for alcohol dependenceDerick E Vergne
Center for Drugs and Alcohol Programs, Department of Psychiatry, Medical University of South Carolina, USA
CNS Neurol Disord Drug Targets 9:50-4. 2010..g., those with impulsive disorders), or non-responsive to available treatments. Early results with aripiprazole are promising and warrant further exploration...
- Gait characteristics of children with hemiplegic cerebral palsy before and after modified constraint-induced movement therapyPatricia Coker
Department of Health Sciences, Medical University of South Carolina, Charleston, South Carolina, USA
Disabil Rehabil 32:402-8. 2010..Additional studies with a longitudinal follow-up focus to determine the long-term effects of mCIMT on walking balance and stability would be beneficial...
- Associations between self-reported quality of care and county characteristics are largely similar in rural and urban settingsLars E Peterson
Department of Family Medicine, Medical University of South Carolina, North Charleston
Qual Manag Health Care 18:257-67. 2009..The extent to which health care consumers' perceptions of the quality of these services vary across settings and the association of these perceptions with features of rural and urban settings are unclear...
- Pediatric emergency medicine fellowship research curriculum: a survey of fellowship directorsM Olivia Titus
Emergency Critical Care Division, Medical University of South Carolina, Charleston, SC 29425, USA
Pediatr Emerg Care 25:550-4. 2009..To determine how pediatric emergency medicine (PEM) fellowship directors organize research training and to identify factors believed to be associated with successful research training...
- Predictors of skin cancer in commercial airline pilotsJoyce S Nicholas
Department of Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston, SC 29425 8350, USA
Occup Med (Lond) 59:434-6. 2009..The reasons for these increases are unclear, but postulated factors include ionizing radiation, circadian disruption and leisure sun exposure...
- Plasma Renin test-guided drug treatment algorithm for correcting patients with treated but uncontrolled hypertension: a randomized controlled trialBrent M Egan
Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA
Am J Hypertens 22:792-801. 2009..65 ng/ml/h) indicates sodium-volume excess "V" hypertension, whereas values >or=0.65 indicate renin-angiotensin vasoconstriction excess "R" hypertension...
- Contrasting roles of checkpoint proteins as recombination modulators at Fob1-Ter complexes with or without fork arrestBidyut K Mohanty
Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29425, USA
Eukaryot Cell 8:487-95. 2009..The work also showed that the two pathways were Rad52 dependent but Rad51 independent. Since Ter sites occur in the intergenic spacer of rDNA from yeast to humans, the mechanism is likely to be of widespread occurrence...
- Structural and functional modifications in glutamateric synapses following prolonged ethanol exposureL Judson Chandler
Alcohol Research Center and Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Alcohol Clin Exp Res 30:368-76. 2006....
- Alcohol dependence and posttraumatic stress disorder: differences in clinical presentation and response to cognitive-behavioral therapy by order of onsetSudie E Back
Department of Psychology, University of Georgia, Athens, GA 30606, USA
J Subst Abuse Treat 29:29-37. 2005..These findings increase awareness of the importance of considering the order of onset and may ultimately lead to treatment improvements for this population...
- Respiratory reovirus 1/L induction of diffuse alveolar damage: a model of acute respiratory distress syndromeLucille London
Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA
Exp Mol Pathol 72:24-36. 2002..Reovirus 1/L infection of CBA/J mice will allow investigations of the pathophysiology of ARDS as it progresses from the initial stages of edema and neutrophilia to fibrotic lesion development in late stages...
- Nifedipine block of capacitative calcium entry in cultured human uterine smooth-muscle cellsR C Young
Department of Obstetrics and Gynecology, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425, USA
J Soc Gynecol Investig 8:210-5. 2001..To determine whether nifedipine inhibits capacitative calcium entry at clinically relevant concentrations using cultured human myocytes as a model for human myometrium...
- Transition programs in cystic fibrosis centers: perceptions of pediatric and adult program directorsP A Flume
Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Pediatr Pulmonol 31:443-50. 2001..These differences may impede the successful transition of patients into an adult program...
- Association of single nucleotide polymorphisms in the interleukin-4 gene and interleukin-4 receptor gene with Crohn's disease in a British populationG P Aithal
Centre for Liver Research, Medical School, University of Newcastle upon Tyne, UK
Genes Immun 2:44-7. 2001..005). Association with alleles resulting in high IL-4 transcription and enhanced signalling activity suggests that IL-4 may have a role in the pathogenesis of Crohn's disease...
- Fading boundary between gastroenterology and surgeryP B Cotton
Digestive Disease Center, Medical University of South Carolina, Charleston 29425, USA
J Gastroenterol Hepatol 15:G34-7. 2000..Patient care, clinical research and education in digestive disorders require structural realignment, as is being attempted in the Digestive Disease Center at the Medical University of South Carolina.
- Pre-clinical in vivo evaluation of orthopaedic bioabsorbable devicesY H An
Department of Orthopaedic Surgery, Medical University of South Carolina, Charleston 29425, USA
Biomaterials 21:2635-52. 2000..In this article we review the pre-clinical in vivo testing of bioabsorbable devices with particular emphasis on implants used for these applications...
- Cocaine dependence with and without post-traumatic stress disorder: a comparison of substance use, trauma history and psychiatric comorbidityS Back
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425, USA
Am J Addict 9:51-62. 2000..Routine assessment of trauma history and PTSD may assist in the identification of a subgroup of cocaine users in need of special prevention and treatment efforts...
- Assessment of the relationship between antimicrobial usage and susceptibility: differences between the hospital and specific patient-care areasR L White
Medical University of South Carolina, College of Pharmacy, Anti Infective Research Laboratory, Charleston, SC, 29425, USA
Clin Infect Dis 31:16-23. 2000..susceptibility and antimicrobial usage data collected over a 5-year period (1992-1996) at the Medical University of South Carolina were analyzed...
- An evaluation of statewide strategies to reduce antibiotic overuseA G Mainous
Department of Family Medicine, Medical University of South Carolina, USA
Fam Med 32:22-9. 2000..This study assessed the utility of two common interventions--1) practice profiling and feedback and 2) patient education materials--implemented to decrease antibiotic prescribing for pediatric upper respiratory infections (URIs)...
- Patient satisfaction with care in programs for low income individualsA G Mainous
Department of Family Medicine, Medical University of South Carolina, Charleston 29425, USA
J Community Health 24:381-91. 1999....
- The recombinant 5-HT1A receptor: G protein coupling and signalling pathwaysJ R Raymond
Division of Nephrology, Department of Medicine, Medical University of South Carolina and the Ralph H Johnson Veterans Affairs Medical Center, Charleston, South Carolina 29425, USA
Br J Pharmacol 127:1751-64. 1999..The current review summarizes the most important studies of the recombinant 5-HT1A receptor in the decade since the identification of its cDNA...
- A systematic study of low-resolution recognition in protein--protein complexesI A Vakser
Department of Cell and Molecular Pharmacology, Medical University of South Carolina, 171 Ashley Avenue, Charleston, SC 29425, USA
Proc Natl Acad Sci U S A 96:8477-82. 1999..However, the results already prove the existence of the low-resolution recognition on a broad scale...
- Differential pharmacology of newer antidepressantsC L DeVane
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425 0742, USA
J Clin Psychiatry 59:85-93. 1998..This review summarizes some of the major pharmacokinetic and pharmacodynamic similarities and differences among these drugs...
- Analysis of elements of interlenticular opacificationLiliana Werner
Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina, Charleston 29425 5536, USA
Am J Ophthalmol 133:320-6. 2002..To report the histopathologic and ultrastructural features of three cases of interlenticular opacification (ILO) between piggyback intraocular lenses...
- Substance abuse treatment outcomes for cognitively impaired and intact outpatientsGordon Teichner
Department of Neurology, Medical University of South Carolina, Charleston 29425, USA
Addict Behav 27:751-63. 2002..Additionally, neuropsychological evaluation may be important in reducing treatment dropouts, as the present findings indicated that greater cognitive impairment was related to an increased likelihood of treatment dropout...
- Clinical significance of eosinophils in suspicious or borderline renal allograft biopsiesO E Emovon
Department of Medicine, University of South Alabama, Mobile, USA
Clin Nephrol 59:367-72. 2003..This report describes clinical course, treatment and long-term outcome of 5 transplant recipients with biopsy histology that showed borderline changes associated with eosinophilic infiltrates...
- Screening antidepressants in the chick separation-stress paradigmMatthew W Feltenstein
Department of Psychology, University of Mississippi, Oxford, MS 38677, USA
Psychopharmacology (Berl) 181:153-9. 2005..However, few animal models of anxiety are sensitive to antidepressants, a finding that may be due to procedures limited to acute administrations...
- An unusual presentation of cystic fibrosis in an adultShoban Dave
Department of Medicine, Medical University of South Carolina, Ralph H Johnson VA Medical Center, Charleston, SC 29425, USA
Am J Kidney Dis 45:e41-4. 2005..These are known complications of CF but are not common presenting features that lead to the diagnosis of CF. The authors discuss their patient's presentation and review his metabolic manifestations of CF...
- Refractive surgery survey 2003Kerry D Solomon
Magill Research Center for Vision Correction, Storm Eye Institute, Medical University of South Carolina, 167 Ashley Avenue, Charleston, SC 29425, USA
J Cataract Refract Surg 30:1556-69. 2004..9% glaucoma specialists, and < 1% retinal/oculoplastics/pediatrics/neurophthalmologists/researchers/retired. Responses were compared with those in the 2001 and 2002 surveys and demonstrate that RS practice patterns continue to evolve...
- Glycemic control in medical inpatients with type 2 diabetes mellitus receiving sliding scale insulin regimens versus routine diabetes medications: a multicenter randomized controlled trialLori M Dickerson
Department of Family Medicine, Medical University of South Carolina, Charleston, SC, USA
Ann Fam Med 1:29-35. 2003....
- Acute coronary artery stenosis during slow pathway ablation for atrioventricular nodal reentrant tachycardia in a childAndrew D Blaufox
Children s Heart Program of South Carolina, Medical University of South Carolina, Charleston, South Carolina 29425, USA
J Cardiovasc Electrophysiol 15:97-100. 2004..Controlled studies are needed to determine the true risk of coronary artery injury during radiofrequency ablation for supraventricular tachycardia, particularly in small children...
- An assessment of racial differences in clinical practices for hypertension at primary care sites for medically underserved patientsDaniel T Lackland
Department of Biometry and Epidemiology, Medical University of South Carolina, Charleston, SC 29425, USA
J Clin Hypertens (Greenwich) 6:26-31; quiz 32-3. 2004..Based on the sites examined, ethnic variations in important process and treatment indicators do not explain racial differences in cardiovascular and renal outcomes...
- Age- and sex-related differences in alcohol and nicotine effects in C57BL/6J miceMarcelo Lopez
Department fo Psychiatry and Behavioral Sciences, Center for Drug and Alcohol Programs, Medical University of South Carolina, Charleston, 29425, USA
Addict Biol 8:419-27. 2003..These results suggest that young C57BL/6J mice are more resistant to both alcohol and nicotine effects. In addition, adult females may be more resistant to acute nicotine effects on temperature and locomotion...
- Twenty-year experience with the St Jude Medical mechanical valve prosthesisJohn S Ikonomidis
Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston 29464, USA
J Thorac Cardiovasc Surg 126:2022-31. 2003We have prospectively followed all adult St Jude Medical mechanical valve recipients at the Medical University of South Carolina since the initial implant in January 1979 and now present our 20-year experience.
- Benefits of continuous subcutaneous insulin infusion in children with type 1 diabetesSteven M Willi
Department of Pediatrics, and the General Clinical Research Center, Medical University of South Carolina, Charleston, South Carolina 29425, USA
J Pediatr 143:796-801. 2003..7+/-3.1 years, mean+/-SD) throughout the 12 months before and after introducing CSII...
- Aggressive juvenile offenders transitioning into emerging adulthood: factors discriminating persistors and desistorsW Glenn Clingempeel
Family Services Research Center, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425, USA
Am J Orthopsychiatry 73:310-23. 2003..Findings largely remained significant after initial group differences were controlled...
- Transcranial Doppler ultrasonography and neurocognitive functioning in children with sickle cell diseaseMary C Kral
Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Pediatrics 112:324-31. 2003..We examined the relationship between cerebral blood flow velocity, measured by transcranial Doppler (TCD) ultrasonography, and neurocognitive functioning...
- Epidemiology of cardiovascular disease in the last decade: treatment options and implications for perfusion in the 21st centuryJoseph J Sistino
Cardiovascular Perfusion Program, Medical University of South Carolina, Charleston 29425, USA
Perfusion 18:73-7. 2003..The continuation of perfusion education programs at their current rate of output seems justified, based on population projections and the increased incidence of CVD in the elderly population...
- Fibroblast growth factor (FGF)-4 can induce proliferation of cardiac cushion mesenchymal cells during early valve leaflet formationYukiko Sugi
Department of Cell Biology and Anatomy and Cardiovascular Developmental Biology Center, Medical University of South Carolina, 171 Ashley Avenue, Charleston, SC 29425, USA
Dev Biol 258:252-63. 2003..Together, these results suggest a role of FGF-4 for cardiac valve leaflet formation through proliferative expansion of cushion mesenchyme...
- Understanding emotional prosody activates right hemisphere regionsM S George
Biological Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
Arch Neurol 53:665-70. 1996..The brain regions involved in recognition of emotional prosody in healthy subjects is less clear...
- Racial Disparities in Diabetes in the US and the UKArch Mainous; Fiscal Year: 2005..abstract_text> ..
- Dietary Fiber and Cardiovascular Inflammatory MarkersDana King; Fiscal Year: 2006..This information could serve to guide constructive changes in nutritional guidelines for reducing CVD risk for millions of at-risk individuals. ..
- Telephone Delivered Behavioral Skills Intervention for Blacks with T2DMLeonard Egede; Fiscal Year: 2009....
- Telephone Delivered Behavioral Skills Intervention for Blacks with T2DMLeonard E Egede; Fiscal Year: 2010....
- Telephone Delivered Behavioral Skills Intervention for Blacks with T2DMLeonard E Egede; Fiscal Year: 2010..The findings of this study, if successful, will provide new information on how to improve quality of care for diabetes in ethnic minorities and reduce the disproportionate burden of diabetes complications and deaths in this population. ..
- INSULIN RESISTANCE AND CARDIOVASCULAR RISK FACTORSBrent Egan; Fiscal Year: 2003..abstract_text> ..
- Fatty Acids, Angiotensin and Oxidative StressBrent Egan; Fiscal Year: 2004..We believe the information generated by the proposed studies has the potential for elucidating biological mechanisms underlying obesity-associated hypertension and the potential for dietary anti-oxidants to modulate BP. ..
- FATTY ACIDS EFFECTS ON VASCULAR REACTIVITYBrent Egan; Fiscal Year: 1999..The studies could provide a basis for longer-term clinical studies on NEFAs and BP regulation as well as basic experiments to elucidate signaling mechanisms. ..
- Risk of Adverse Outcomes after Spinal Cord Injury: A Longitudinal StudyJames S Krause; Fiscal Year: 2010..abstract_text> ..
- Risk of Adverse Outcomes after Spinal Cord Injury: A Longitudinal StudyJames Krause; Fiscal Year: 2007....
- A PROSPECTIVE STUDY OF RISK OF MORTALITY AFTER SCIJames Krause; Fiscal Year: 2002..Risk profiles will be generated to identify individuals at greatest risk for early mortality. Separate analyses and risk profiles will be generated based on injury severity, gender and race/ethnicity. ..
- Optimization of TMS for DepressionMark George; Fiscal Year: 2009..This clinical site grant (CSG) proposal is one of four scientifically identical proposals resubmitted under a CSMD mechanism.] ..
- Optimization of TMS for Depression - Coordinating CenterMark George; Fiscal Year: 2009..This coordinating Center Grant (CCG) application is submitted under a CSMD mechanism, linked to 4 clinical site grants (CSG). ..
- MOOD EFFECTS OF DEEP BRAIN STIMULATION IN PARKINSONSMark George; Fiscal Year: 2002..Thus, we plan to use interleaved fMRI and DBS to directly examine the effects of DBS on hypothesized brain circuits and to correlate this with immediate and longer-term (4 week) behavioral outcomes (mood and cognition). ..
- GLUTAMATE AND CRAVING FOR COCAINEPeter Kalivas; Fiscal Year: 2009..The overarching goal of the proposal is to identify novel molecular targets for pharmacotherapeutic intervention in cocaine craving and relapse. ..
- GLUTAMATE AND CRAVING FOR COCAINEPeter W Kalivas; Fiscal Year: 2010....
- Cocaine, Opoids and Drug AbusePeter W Kalivas; Fiscal Year: 2010..Accordingly, we propose to characterize the ability of daily N-acetylcysteine treatment to produce enduring protection from the reinstatement of cocaine seeking, and associate this protection with restoring neuroplasticity. ..
- Immunoglobulin Allotypes in Hepatitis C Virus InfectionJANARDAN PANDEY; Fiscal Year: 2007..Results of this investigation will advance our understanding of the role of host genetic factors in clearance and persistence of hepatitis C virus infection. ..
- Stress-induced reinstatement of cocaine-seeking behaviorPeter Kalivas; Fiscal Year: 2007..abstract_text> ..
- Neurobiology of Addiction Research Center (NARC)Peter Kalivas; Fiscal Year: 2007..The NARC also takes advantage of the rapid growth in basic neuroscience at MUSC, as well as the existing clinical strengths in addiction research to provide a means for actively mentoring faculty and trainees. ..
- REGULATION OF MESOLIMBIC DOPAMINE BY ENDOGENOUS COMPOUNDPeter Kalivas; Fiscal Year: 1999....
- COCAINE, OPIOIDS AND DRUG ABUSEPeter Kalivas; Fiscal Year: 2007..abstract_text> ..