Lifeng Yu

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. doi request reprint Automatic selection of tube potential for radiation dose reduction in vascular and contrast-enhanced abdominopelvic CT
    Lifeng Yu
    Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    AJR Am J Roentgenol 201:W297-306. 2013
  2. pmc Prediction of human observer performance in a 2-alternative forced choice low-contrast detection task using channelized Hotelling observer: impact of radiation dose and reconstruction algorithms
    Lifeng Yu
    Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Med Phys 40:041908. 2013
  3. pmc Virtual monochromatic imaging in dual-source dual-energy CT: radiation dose and image quality
    Lifeng Yu
    Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Med Phys 38:6371-9. 2011
  4. doi request reprint Development and validation of a practical lower-dose-simulation tool for optimizing computed tomography scan protocols
    Lifeng Yu
    Department of Radiology, Mayo Clinic, Rochester, MN, USA
    J Comput Assist Tomogr 36:477-87. 2012
  5. doi request reprint Dose and image quality evaluation of a dedicated cone-beam CT system for high-contrast neurologic applications
    Lifeng Yu
    Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
    AJR Am J Roentgenol 194:W193-201. 2010
  6. ncbi request reprint Automatic selection of tube potential for radiation dose reduction in CT: a general strategy
    Lifeng Yu
    Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Med Phys 37:234-43. 2010
  7. doi request reprint Optimal tube potential for radiation dose reduction in pediatric CT: principles, clinical implementations, and pitfalls
    Lifeng Yu
    Department of Radiology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
    Radiographics 31:835-48. 2011
  8. pmc Image quality optimization and evaluation of linearly mixed images in dual-source, dual-energy CT
    Lifeng Yu
    Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Med Phys 36:1019-24. 2009
  9. pmc Metal artifact reduction from reformatted projections for hip prostheses in multislice helical computed tomography: techniques and initial clinical results
    Lifeng Yu
    Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Invest Radiol 44:691-6. 2009
  10. doi request reprint Noise reduction to decrease radiation dose and improve conspicuity of hepatic lesions at contrast-enhanced 80-kV hepatic CT using projection space denoising
    Eric C Ehman
    Mayo Medical School, Rochester, MN, USA
    AJR Am J Roentgenol 198:405-11. 2012

Collaborators

Detail Information

Publications77

  1. doi request reprint Automatic selection of tube potential for radiation dose reduction in vascular and contrast-enhanced abdominopelvic CT
    Lifeng Yu
    Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    AJR Am J Roentgenol 201:W297-306. 2013
    ..The purpose of this study is to assess the ability of a novel automatic tube potential selection tool to reduce radiation dose while maintaining diagnostic quality in CT angiography (CTA) and contrast-enhanced abdominopelvic CT...
  2. pmc Prediction of human observer performance in a 2-alternative forced choice low-contrast detection task using channelized Hotelling observer: impact of radiation dose and reconstruction algorithms
    Lifeng Yu
    Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Med Phys 40:041908. 2013
    ....
  3. pmc Virtual monochromatic imaging in dual-source dual-energy CT: radiation dose and image quality
    Lifeng Yu
    Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Med Phys 38:6371-9. 2011
    ..To evaluate the image quality of virtual monochromatic images synthesized from dual-source dual-energy computed tomography (CT) in comparison with conventional polychromatic single-energy CT for the same radiation dose...
  4. doi request reprint Development and validation of a practical lower-dose-simulation tool for optimizing computed tomography scan protocols
    Lifeng Yu
    Department of Radiology, Mayo Clinic, Rochester, MN, USA
    J Comput Assist Tomogr 36:477-87. 2012
    ..The objective of this study was to develop and validate a novel noise insertion method that can accurately simulate lower-dose images from existing standard-dose computed tomography (CT) data...
  5. doi request reprint Dose and image quality evaluation of a dedicated cone-beam CT system for high-contrast neurologic applications
    Lifeng Yu
    Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
    AJR Am J Roentgenol 194:W193-201. 2010
    ..The purpose of our study was to evaluate the dose and image quality performance of a dedicated cone-beam CT (CBCT) scanner in comparison with an MDCT scanner...
  6. ncbi request reprint Automatic selection of tube potential for radiation dose reduction in CT: a general strategy
    Lifeng Yu
    Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Med Phys 37:234-43. 2010
    ..The purpose of this work was to develop a general strategy that allows for automatic tube potential selection for each individual patient and each diagnostic task...
  7. doi request reprint Optimal tube potential for radiation dose reduction in pediatric CT: principles, clinical implementations, and pitfalls
    Lifeng Yu
    Department of Radiology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
    Radiographics 31:835-48. 2011
    ..The use of a lower tube potential and the amount by which to reduce radiation dose must be carefully evaluated for each type of examination to achieve an optimal tradeoff between contrast, noise, artifacts, and scanning speed...
  8. pmc Image quality optimization and evaluation of linearly mixed images in dual-source, dual-energy CT
    Lifeng Yu
    Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Med Phys 36:1019-24. 2009
    ....
  9. pmc Metal artifact reduction from reformatted projections for hip prostheses in multislice helical computed tomography: techniques and initial clinical results
    Lifeng Yu
    Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Invest Radiol 44:691-6. 2009
    ..The purpose of this work was to develop a projection-based method for reducing metal artifacts caused by hip prostheses in multislice helical CT...
  10. doi request reprint Noise reduction to decrease radiation dose and improve conspicuity of hepatic lesions at contrast-enhanced 80-kV hepatic CT using projection space denoising
    Eric C Ehman
    Mayo Medical School, Rochester, MN, USA
    AJR Am J Roentgenol 198:405-11. 2012
    ..The purpose of this study was to investigate the combined potential of 80-kV CT and noise reduction using a projection space denoising algorithm to reduce radiation dose reduction or to improve the image quality of hepatic CT...
  11. ncbi request reprint Metal artifact suppression from reformatted projections in multislice helical CT using dual-front active contours
    Hua Li
    Department of Radiology, Mayo Clinic College of Medicine Rochester, 200 First Avenue, SW, Rochester, Minnesota 55905, USA
    Med Phys 37:5155-64. 2010
    ....
  12. ncbi request reprint Region of interest reconstruction from truncated data in circular cone-beam CT
    Lifeng Yu
    Department of Radiology, The University of Chicago, Chicago, IL 60637, USA
    IEEE Trans Med Imaging 25:869-81. 2006
    ..Quantitative results in these studies demonstrate that the proposed BPF algorithms for circular cone-beam CT can reconstruct ROI images free of truncation artifacts...
  13. doi request reprint Comparative study of two image space noise reduction methods for computed tomography: bilateral filter and nonlocal means
    Juan C Ramirez Giraldo
    CT Clinical Innovation Center, Dept of Radiology, Mayo Clinic, Rochester, MN, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:3529-32. 2009
    ..Care must be taken when choosing the NLM parameters in order to minimize the generation of artifacts that could possibly compromise diagnostic value...
  14. doi request reprint Individualization of abdominopelvic CT protocols with lower tube voltage to reduce i.v. contrast dose or radiation dose
    David M Hough
    Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    AJR Am J Roentgenol 201:147-53. 2013
    ..The purpose of this study was to validate an individualized approach to contrast-enhanced body CT using size-specific tube potential selection to reduce either i.v. contrast or radiation dose while maintaining diagnostic image quality...
  15. doi request reprint Individualized kV selection and tube current reduction in excretory phase computed tomography urography: potential for radiation dose reduction and the contribution of iterative reconstruction to image quality
    Adam T Froemming
    Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
    J Comput Assist Tomogr 37:551-9. 2013
    ..The objective of this study was to analyze radiation dose reduction and image quality by combining automated kV selection, tube current reduction, and iterative reconstruction...
  16. pmc Feasibility of dose reduction using novel denoising techniques for low kV (80 kV) CT enterography: optimization and validation
    Luis S Guimaraes
    Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
    Acad Radiol 17:1203-10. 2010
    ..The aim of this study was to optimize and validate projection-space denoising (PSDN) strategies for application to 80-kV computed tomographic (CT) data to achieve 50% dose reduction...
  17. ncbi request reprint Noise properties of chord-image reconstruction
    Dan Xia
    Department of Radiology, The University of Chicago, Chicago, IL 60637, USA
    IEEE Trans Med Imaging 26:1328-44. 2007
    ..Additionally, it is observed that, in many situations, large data sets contain extraneous data that may not reduce the ROI-image variances...
  18. pmc Projection space denoising with bilateral filtering and CT noise modeling for dose reduction in CT
    Armando Manduca
    Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Med Phys 36:4911-9. 2009
    ..To investigate a novel locally adaptive projection space denoising algorithm for low-dose CT data...
  19. doi request reprint Metal artifact suppression from reformatted projections in multi-slice helical CT using dual-front active contours
    Hua Li
    Department of Radiology, Mayo Clinic, Rochester, MN 55901, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:993-6. 2009
    ..The artifacts caused by dense metal implants were better suppressed...
  20. ncbi request reprint A rebinned backprojection-filtration algorithm for image reconstruction in helical cone-beam CT
    Lifeng Yu
    Department of Radiology, Mayo Clinic, Rochester, MN, USA
    Phys Med Biol 52:5497-508. 2007
    ..We have also performed simulation studies to validate and evaluate the rebinned BPF algorithm...
  21. pmc Human Imaging With Photon Counting-Based Computed Tomography at Clinical Dose Levels: Contrast-to-Noise Ratio and Cadaver Studies
    Ralf Gutjahr
    From the CAMP, Technical University of Munich, Munich, Germany Siemens Healthcare Imaging and Therapy Systems, Malvern, PA Departments of Radiology, and Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN and Siemens Healthcare, Forchheim, Germany
    Invest Radiol 51:421-9. 2016
    ....
  22. doi request reprint Methods for clinical evaluation of noise reduction techniques in abdominopelvic CT
    Eric C Ehman
    From the Departments of Radiology E C E, L Y, A M, M M S, D J, M R B, C H M, D M H, J G F and Biomedical Engineering D S L, D J B, Mayo Clinic, 200 First St SW, Rochester, MN 55905 and Department of Radiology, Mayo Clinic, Scottsdale, Ariz A K H, R G P
    Radiographics 34:849-62. 2014
    ....
  23. doi request reprint Spatial resolution improvement and dose reduction potential for inner ear CT imaging using a z-axis deconvolution technique
    Cynthia H McCollough
    Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Med Phys 40:061904. 2013
    ....
  24. doi request reprint Lowering kilovoltage to reduce radiation dose in contrast-enhanced abdominal CT: initial assessment of a prototype automated kilovoltage selection tool
    David M Hough
    Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    AJR Am J Roentgenol 199:1070-7. 2012
    ..The purpose of this study was to determine whether the use of an automated CT kilovoltage (kV) selection tool (Auto kV) can result in lower radiation dose without sacrificing image quality in contrast-enhanced abdominopelvic CT...
  25. pmc Renal perfusion and hemodynamics: accurate in vivo determination at CT with a 10-fold decrease in radiation dose and HYPR noise reduction
    Xin Liu
    Department of Radiology, Divisions of Nephrology and Hypertension, CT Clinical Innovation Center, Mayo Clinic, Rochester, MN 55905, USA
    Radiology 253:98-105. 2009
    ....
  26. doi request reprint Attenuation-based estimation of patient size for the purpose of size specific dose estimation in CT. Part II. Implementation on abdomen and thorax phantoms using cross sectional CT images and scanned projection radiograph images
    Jia Wang
    Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
    Med Phys 39:6772-8. 2012
    ..To estimate attenuation using cross sectional CT images and scanned projection radiograph (SPR) images in a series of thorax and abdomen phantoms...
  27. doi request reprint Attenuation-based estimation of patient size for the purpose of size specific dose estimation in CT. Part I. Development and validation of methods using the CT image
    Jia Wang
    Department of Radiology, Mayo Clinic, Rochester, MN, USA
    Med Phys 39:6764-71. 2012
    ..The ability to calculate A(w) directly from the CT image was validated with Monte Carlo simulations and an analytical model...
  28. doi request reprint Radiation dose reduction to the breast in thoracic CT: comparison of bismuth shielding, organ-based tube current modulation, and use of a globally decreased tube current
    Jia Wang
    Department of Radiology, Mayo Clinic, Rochester, MN, USA
    Med Phys 38:6084-92. 2011
    ..The purpose of this work was to evaluate dose performance and image quality in thoracic CT using three techniques to reduce dose to the breast: bismuth shielding, organ-based tube current modulation (TCM) and global tube current reduction...
  29. ncbi request reprint Region-of-interest reconstruction of motion-contaminated data using a weighted backprojection filtration algorithm
    Martin King
    Department of Radiology, The University of Chicago, USA
    Med Phys 33:1222-38. 2006
    ..9%. As a result of our studies, we believe that the WBPF algorithm demonstrates the potential for reconstructing quality ROI images from motion-contaminated fan-beam data...
  30. pmc Quantitative imaging of element composition and mass fraction using dual-energy CT: three-material decomposition
    Xin Liu
    Mayo Clinic, Rochester, Minnesota 55905, USA
    Med Phys 36:1602-9. 2009
    ..Clinically, this may be applied to measure the mass fraction of any chemical element in a three-material mixture of solutions without the requirement of volume conservation...
  31. pmc Observer performance for adaptive, image-based denoising and filtered back projection compared to scanner-based iterative reconstruction for lower dose CT enterography
    Joel G Fletcher
    Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA
    Abdom Imaging 40:1050-9. 2015
    ..vendor-independent, adaptive image-based noise reduction (ANLM) or filtered back projection (FBP)...
  32. pmc A cross-platform survey of CT image quality and dose from routine abdomen protocols and a method to systematically standardize image quality
    Christopher P Favazza
    Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55902, USA
    Phys Med Biol 60:8381-97. 2015
    ..3-28.8 mGy for the medium phantom; and 7.8-23.4 HU and 16.0-48.1 mGy for the largest phantom. Using these measurements and benchmark SSP, MTF, and image noise targets, CT image quality can be standardized across a range of patient sizes. ..
  33. pmc Genitourinary applications of dual-energy CT
    Terri J Vrtiska
    Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
    AJR Am J Roentgenol 194:1434-42. 2010
    ..In addition, improved material characterization and creation of virtual unenhanced techniques potentially result in decreased radiation dose. We will review the role of dual-energy CT as applied to the genitourinary system...
  34. ncbi request reprint Validation of dual-source single-tube reconstruction as a method to obtain half-dose images to evaluate radiation dose and noise reduction: phantom and human assessment using CT colonography and sinogram-affirmed iterative reconstruction (SAFIRE)
    Joel G Fletcher
    Department of Radiology, Mayo Clinic, Rochester, MN, USA
    J Comput Assist Tomogr 36:560-9. 2012
    ..To evaluate a method for obtaining half-dose CT images for observer studies evaluating lower-dose CT...
  35. pmc A strategy to decrease partial scan reconstruction artifacts in myocardial perfusion CT: phantom and in vivo evaluation
    Juan C Ramirez-Giraldo
    Department of Radiology, CT Clinical Innovation Center, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Med Phys 39:214-23. 2012
    ..The purpose of this work is to present and evaluate a technique termed targeted spatial frequency filtration (TSFF) to reduce CT number variations due to PSR when applied to myocardial perfusion imaging using MDCT...
  36. doi request reprint Quantification of iron in the presence of calcium with dual-energy computed tomography (DECT) in an ex vivo porcine plaque model
    Jia Wang
    Department of Radiology, Mayo Clinic, Rochester, MN, USA
    Phys Med Biol 56:7305-16. 2011
    ..Iron quantification in the presence of calcium was feasible in excised arteries at an iron mass fraction of around 1.5% or higher using current clinical DECT scanners...
  37. pmc Measurement of temporal resolution in dual source CT
    Cynthia H McCollough
    Department of Radiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Med Phys 35:764-8. 2008
    ..A demonstration of the effect of the evaluated 165 and 83 ms nominal temporal resolutions on motion artifacts in cardiac CT is provided using patient data...
  38. doi request reprint Appropriate patient selection at abdominal dual-energy CT using 80 kV: relationship between patient size, image noise, and image quality
    Luis S Guimaraes
    Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Radiology 257:732-42. 2010
    ..To determine the computed tomographic (CT) detector configuration, patient size, and image noise limitations that will result in acceptable image quality of 80-kV images obtained at abdominal dual-energy CT...
  39. pmc Validation of a Projection-domain Insertion of Liver Lesions into CT Images
    Baiyu Chen
    Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905
    Acad Radiol 23:1221-9. 2016
    ..The aim of this study was to validate a projection-domain lesion-insertion method with observer studies...
  40. pmc Evaluation of conventional imaging performance in a research whole-body CT system with a photon-counting detector array
    Zhicong Yu
    Department of Radiology, Mayo Clinic Rochester, Minnesota, 55905, USA
    Phys Med Biol 61:1572-95. 2016
    ..Our experiments demonstrated that the research whole-body photon-counting CT system is capable of providing clinical image quality at clinically realistic levels of x-ray photon flux. ..
  41. pmc Characterization of Urinary Stone Composition by Use of Third-Generation Dual-Source Dual-Energy CT With Increased Spectral Separation
    Xinhui Duan
    1 Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905
    AJR Am J Roentgenol 205:1203-7. 2015
    ..The purpose of this phantom study was to determine the utility of a third-generation dual-source CT scanner with increased dual-energy spectral separation in differentiating urinary stone composition...
  42. doi request reprint A robust noise reduction technique for time resolved CT
    Zhoubo Li
    Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905 and Biomedical Engineering and Physiology Graduate Program, Mayo Graduate School, Rochester, Minnesota 55905
    Med Phys 43:347. 2016
    ..To develop a noise reduction method for time resolved CT data, especially those with significant patient motion...
  43. pmc Degradation of CT Low-Contrast Spatial Resolution Due to the Use of Iterative Reconstruction and Reduced Dose Levels
    Cynthia H McCollough
    From the Department of Radiology C H M, L Y, J M K, S L, Y Z, Z L and Department of Health Sciences Research, Division of Biomedical Statistics and Informatics R E C, Mayo Clinic, 200 First St SW, Rochester, MN 55905
    Radiology 276:499-506. 2015
    ....
  44. pmc Assessment of Low-Contrast Resolution for the American College of Radiology Computed Tomographic Accreditation Program: What Is the Impact of Iterative Reconstruction?
    James M Kofler
    From the Departments of Radiology and Health Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN
    J Comput Assist Tomogr 39:619-23. 2015
    ..To compare contrast-to-noise ratio (CNR) thresholds with visual assessment of low-contrast resolution (LCR) in filtered back projection (FBP) and iteratively reconstructed (IR) computed tomographic (CT) images...
  45. pmc Radiation Dose Reduction in Dual-Energy CT: Does It Affect the Accuracy of Urinary Stone Characterization?
    Mingliang Qu
    1 Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905
    AJR Am J Roentgenol 205:W172-6. 2015
    ..The purpose of this article is to assess the effect of radiation dose reduction in dual-energy CT (DECT) on the performance of renal stone characterization using a patient cohort...
  46. pmc Observer Performance in the Detection and Classification of Malignant Hepatic Nodules and Masses with CT Image-Space Denoising and Iterative Reconstruction
    Joel G Fletcher
    From the Departments of Radiology J G F, L Y, Z L, D M H, S K V, J L F, M S, D L, S L, C H M, Physiology and Biomedical Engineering A M, D S L, K E A, D R H, Information Technology D J B, and Biomedical Statistics and Informatics R E C, Mayo Clinic, 200 First St SW, Rochester, MN 55905 Department of Radiology, Mayo Clinic, Eau Claire, Wis G C B Department of Radiology, Mayo Clinic, Jacksonville, Fla J C C and Department of Radiology, Mayo Clinic, Scottsdale, Ariz A K H
    Radiology 276:465-78. 2015
    ....
  47. doi request reprint Reducing radiation dose in CT enterography
    Andrew J Del Gaizo
    Department of Radiology, Mayo Clinic, 13400 E Shea Blvd, Scottsdale, AZ 85259, USA
    Radiographics 33:1109-24. 2013
    ..With a combination of low-dose techniques and noise-control strategies, one can markedly reduce radiation dose at CT enterography while maintaining diagnostic accuracy...
  48. doi request reprint Dual-energy and dual-source CT: is there a role in the abdomen and pelvis?
    Joel G Fletcher
    Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Radiol Clin North Am 47:41-57. 2009
    ..This article summarizes and reviews current and potential applications for dual-energy and dual-source CT in the abdomen and pelvis...
  49. pmc Imaging evaluation and treatment of nephrolithiasis: an update
    Terri J Vrtiska
    Department of Radiology, Mayo Clinic, USA
    Minn Med 93:48-51. 2010
    ..Improvements in percutaneous therapy have led to less-invasive and less-costly treatments for nephrolithiasis. This article describes some of these new approaches to diagnosing and caring for patients with renal stone disease...
  50. ncbi request reprint Spatial-resolution enhancement in computed tomography
    Xiaochuan Pan
    Department of Radiology, The University of Chicago, Chicago, IL 60637, USA
    IEEE Trans Med Imaging 24:246-53. 2005
    ..The proposed acquisition/reconstruction approach may find applications in micro-CT and industrial CT in which the CORs may be changed...
  51. pmc Strategies for reducing radiation dose in CT
    Cynthia H McCollough
    Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Radiol Clin North Am 47:27-40. 2009
    ..To satisfy the ALARA principle, the dose reduction strategies described in this article must be well understood and properly used. The use of CT must also be justified for the specific diagnostic task...
  52. doi request reprint Noise reduction in spectral CT: reducing dose and breaking the trade-off between image noise and energy bin selection
    Shuai Leng
    Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Med Phys 38:4946-57. 2011
    ..Our purpose was to reduce image noise in spectral CT by exploiting data redundancies in the energy domain to allow flexible selection of the number, width, and location of the energy bins...
  53. pmc Construction of realistic phantoms from patient images and a commercial three-dimensional printer
    Shuai Leng
    Mayo Clinic, Department of Radiology, 200 First Street SW, Rochester, Minnesota 55905, United States
    J Med Imaging (Bellingham) 3:033501. 2016
    ..CT images of the brain phantom had CT numbers of 125, 134, and 108 HU for white matter, gray matter, and CSF, respectively. The CT number differences were similar to those in patient images. ..
  54. pmc Impact of number of repeated scans on model observer performance for a low-contrast detection task in computed tomography
    Chi Ma
    Mayo Clinic, Department of Radiology, 200 First Street SW, Rochester, Minnesota 55905, United States
    J Med Imaging (Bellingham) 3:023504. 2016
    ..As a general trend, it increased as the low-contrast detectability decreased. This study provides a basis for the experimental design of task-based image quality assessment in clinical CT using CHO. ..
  55. pmc Predicting detection performance with model observers: Fourier domain or spatial domain?
    Baiyu Chen
    Department of Radiology, Mayo Clinic, Rochester, MN 55905
    Proc SPIE Int Soc Opt Eng 9783:. 2016
    ..The Fourier domain observer correlated well with human observers using FBP images, but overestimated the detection performance using IR images...
  56. pmc An Open Library of CT Patient Projection Data
    Baiyu Chen
    Department of Radiology, Mayo Clinic, Rochester, MN 55905 USA
    Proc SPIE Int Soc Opt Eng 9783:. 2016
    ..It will be freely available to academic researchers, and is expected to greatly facilitate the development and validation of CT reconstruction algorithms...
  57. pmc Size-specific Dose Estimates for Chest, Abdominal, and Pelvic CT: Effect of Intrapatient Variability in Water-equivalent Diameter
    Shuai Leng
    From the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905
    Radiology 276:184-90. 2015
    ..To develop software to automatically calculate size-specific dose estimates (SSDEs) and to assess the effect of variations in water-equivalent diameter (Dw) along the z-axis on SSDE for computed tomographic (CT) examinations of the torso...
  58. doi request reprint Adaptive nonlocal means filtering based on local noise level for CT denoising
    Zhoubo Li
    Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota 55905
    Med Phys 41:011908. 2014
    ....
  59. pmc Achieving routine submillisievert CT scanning: report from the summit on management of radiation dose in CT
    Cynthia H McCollough
    Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
    Radiology 264:567-80. 2012
    ....
  60. ncbi request reprint A unified analysis of FBP-based algorithms in helical cone-beam and circular cone- and fan-beam scans
    Xiaochuan Pan
    Department of Radiology, The University of Chicago, 5841 S Maryland Avenue, Chicago, IL 60637, USA
    Phys Med Biol 49:4349-69. 2004
    ..We also performed a preliminary numerical study to verify our theoretical results in each of the cases. The results in the work can readily be generalized to other non-circular trajectories...
  61. pmc Radiation Dose Reduction in Pediatric Body CT Using Iterative Reconstruction and a Novel Image-Based Denoising Method
    Lifeng Yu
    1 All authors Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905
    AJR Am J Roentgenol 205:1026-37. 2015
    ....
  62. pmc Technical Note: Measuring contrast- and noise-dependent spatial resolution of an iterative reconstruction method in CT using ensemble averaging
    Lifeng Yu
    Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905
    Med Phys 42:2261-7. 2015
    ..The purpose of this study was to measure the spatial resolution of a commercially available IR method using ensemble-averaged images acquired from repeated scans...
  63. pmc Lesion insertion in the projection domain: Methods and initial results
    Baiyu Chen
    Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905
    Med Phys 42:7034-42. 2015
    ..Because conventional hybrid images generated in the image domain fails to reflect the impact of scan and reconstruction parameters on lesion appearance, this study explored a projection-domain approach...
  64. pmc Correlation between human and model observer performance for discrimination task in CT
    Yi Zhang
    Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Phys Med Biol 59:3389-404. 2014
    ..For this shape discrimination task with uniform background, IR significantly improved human and model observer performance compared to FBP, with the amount of improvement depending on lesion size, contrast and dose. ..
  65. doi request reprint Radiation dose reduction for CT-guided renal tumor cryoablation
    Shuai Leng
    Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
    AJR Am J Roentgenol 196:W586-91. 2011
    ..The purpose of this article is to retrospectively determine the image quality and degree of radiation dose reduction that is clinically acceptable for CT-guided renal tumor cryoablation...
  66. doi request reprint Technical Note: Improved CT number stability across patient size using dual-energy CT virtual monoenergetic imaging
    Gregory Michalak
    Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905
    Med Phys 43:513. 2016
    ..The purpose of this study was to evaluate, over a wide range of phantom sizes, CT number stability achieved using two techniques for generating dual-energy computed tomography (DECT) virtual monoenergetic images...
  67. pmc Technical Note: Development and validation of an open data format for CT projection data
    Baiyu Chen
    Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905
    Med Phys 42:6964-72. 2015
    ..To meet this critical need, this work developed and validated a vendor-neutral format for CT projection data, which will further be employed to build a library of patient projection data for public access...
  68. pmc Dual- and Multi-Energy CT: Principles, Technical Approaches, and Clinical Applications
    Cynthia H McCollough
    From the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905
    Radiology 276:637-53. 2015
    ..In this review, the underlying motivation and physical principles of dual- or multi-energy CT are reviewed and each of the current technical approaches is described. In addition, current and evolving clinical applications are introduced...
  69. pmc Maximizing Iodine Contrast-to-Noise Ratios in Abdominal CT Imaging through Use of Energy Domain Noise Reduction and Virtual Monoenergetic Dual-Energy CT
    Shuai Leng
    From the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905
    Radiology 276:562-70. 2015
    ....
  70. pmc Automatic exposure control systems designed to maintain constant image noise: effects on computed tomography dose and noise relative to clinically accepted technique charts
    Christopher P Favazza
    From the Department of Radiology, Mayo Clinic, Rochester, MN
    J Comput Assist Tomogr 39:437-42. 2015
    ....
  71. pmc Correlation between model observer and human observer performance in CT imaging when lesion location is uncertain
    Shuai Leng
    Department of Radiology, Mayo Clinic, 200 First Street Southwest, Rochester, Minnesota 55905, USA
    Med Phys 40:081908. 2013
    ..The purpose of this study was to investigate the correlation between model observer and human observer performance in CT imaging for the task of lesion detection and localization when the lesion location is uncertain...
  72. pmc Three-dimensional volumetric computed tomographic scoring as an objective outcome measure for chronic rhinosinusitis: clinical correlations and comparison to Lund-Mackay scoring
    John F Pallanch
    Department of Otorhinolaryngology Head and Neck Surgery, Mayo Clinic, Rochester, MN
    Int Forum Allergy Rhinol 3:963-72. 2013
    ..We determined correlation between changes in CT scores (using each scoring system) with changes in other measures of disease severity (symptoms, endoscopic scoring, and quality of life) in patients with CRS treated with triamcinolone...
  73. doi request reprint Dual-energy CT-based monochromatic imaging
    Lifeng Yu
    Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    AJR Am J Roentgenol 199:S9-S15. 2012
    ..Clinical applications of dual-energy CT-based virtual monochromatic imaging are reviewed, including beam-hardening correction, contrast and noise optimization, metal artifact reduction, and material differentiation...
  74. pmc CT scanner x-ray spectrum estimation from transmission measurements
    Xinhui Duan
    Department of Radiology, Mayo Clinic, 200 First Street Southwest, Rochester, Minnesota 55905, USA
    Med Phys 38:993-7. 2011
    ..The expectation maximization (EM) method is an accurate and robust method to solve this problem. In this article, this method was evaluated in a commercial CT scanner...
  75. ncbi request reprint Image reconstruction with shift-variant filtration and its implication for noise and resolution properties in fan-beam computed tomography
    Xiaochuan Pan
    Department of Radiology, MC2026, The University of Chicago, Chicago, Illinois 60637, USA
    Med Phys 30:590-600. 2003
    ....
  76. ncbi request reprint Half-scan fan-beam computed tomography with improved noise and resolution properties
    Lifeng Yu
    Department of Radiology, MC2026, 5841 S Maryland Avenue, The University of Chicago, Chicago, Illinois 60637, USA
    Med Phys 30:2629-37. 2003
    ..The analytic results of the image-noise properties can be used for image-quality assessment in detection/classification tasks by use of model-observers...
  77. doi request reprint Use of CT dose notification and alert values in routine clinical practice
    Michelle E Howard
    Department of Radiology, Mayo Clinic, Rochester, Minnesota
    J Am Coll Radiol 11:450-5. 2014
    ..The purpose of this investigation was to assess the impact on workflow of the use of notification and alert values in our practice and to provide baseline data for quality improvement initiatives...