Tom D Thacher

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. doi request reprint CYP2R1 mutations causing vitamin D-deficiency rickets
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA Electronic address
    J Steroid Biochem Mol Biol . 2016
  2. doi request reprint Comparison of Limestone and Ground Fish for Treatment of Nutritional Rickets in Children in Nigeria
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, Rochester, MN Electronic address
    J Pediatr 167:148-54.e1. 2015
  3. pmc Increasing incidence of nutritional rickets: a population-based study in Olmsted County, Minnesota
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, Rochester, MN, USA
    Mayo Clin Proc 88:176-83. 2013
  4. doi request reprint Prevention of nutritional rickets in Nigerian children with dietary calcium supplementation
    Tom D Thacher
    Department of Family Medicine TDT, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA
    Bone 50:1074-80. 2012
  5. pmc Meals and dephytinization affect calcium and zinc absorption in Nigerian children with rickets
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, Rochester, MN 55903, USA
    J Nutr 139:926-32. 2009
  6. pmc Vitamin D insufficiency
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 86:50-60. 2011
  7. doi request reprint Relationship of calcium absorption with 25(OH)D and calcium intake in children with rickets
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Nutr Rev 68:682-8. 2010
  8. pmc Comparison of metabolism of vitamins D2 and D3 in children with nutritional rickets
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Bone Miner Res 25:1988-95. 2010
  9. pmc The effect of vitamin D2 and vitamin D3 on intestinal calcium absorption in Nigerian children with rickets
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    J Clin Endocrinol Metab 94:3314-21. 2009
  10. pmc Maternal vitamin D supplementation to improve the vitamin D status of breast-fed infants: a randomized controlled trial
    Sara S Oberhelman
    Department of Family Medicine, Mayo Clinic, Rochester, MN Electronic address
    Mayo Clin Proc 88:1378-87. 2013

Collaborators

Detail Information

Publications21

  1. doi request reprint CYP2R1 mutations causing vitamin D-deficiency rickets
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA Electronic address
    J Steroid Biochem Mol Biol . 2016
    ..We conclude that mutations in CYP2R1 are responsible for an atypical form of vitamin D-deficiency rickets, which has been classified as vitamin D dependent rickets type 1B (VDDR1B, MIM 600081)...
  2. doi request reprint Comparison of Limestone and Ground Fish for Treatment of Nutritional Rickets in Children in Nigeria
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, Rochester, MN Electronic address
    J Pediatr 167:148-54.e1. 2015
    ..To determine whether children with calcium-deficiency rickets respond better to treatment with calcium as limestone or as ground fish...
  3. pmc Increasing incidence of nutritional rickets: a population-based study in Olmsted County, Minnesota
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, Rochester, MN, USA
    Mayo Clin Proc 88:176-83. 2013
    ..To determine temporal trends in incidence and risk factors of nutritional rickets in a community-based population...
  4. doi request reprint Prevention of nutritional rickets in Nigerian children with dietary calcium supplementation
    Tom D Thacher
    Department of Family Medicine TDT, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA
    Bone 50:1074-80. 2012
    ..04). We conclude that calcium supplementation increased areal bone density at the radius and ulna, but a larger sample size would be required to determine its effect on the incidence of rickets...
  5. pmc Meals and dephytinization affect calcium and zinc absorption in Nigerian children with rickets
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, Rochester, MN 55903, USA
    J Nutr 139:926-32. 2009
    ..Enzymatic dephytinization increased zinc absorption. Multiple strategies may be required to optimize calcium and zinc absorption in deficient populations...
  6. pmc Vitamin D insufficiency
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 86:50-60. 2011
    ..Conclusive demonstration of these benefits awaits the outcome of controlled clinical trials...
  7. doi request reprint Relationship of calcium absorption with 25(OH)D and calcium intake in children with rickets
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Nutr Rev 68:682-8. 2010
    ..More research is needed to understand the interaction between calcium and vitamin D and the role of vitamin D in calcium absorption...
  8. pmc Comparison of metabolism of vitamins D2 and D3 in children with nutritional rickets
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Bone Miner Res 25:1988-95. 2010
    ..2010 American Society for Bone and Mineral Research...
  9. pmc The effect of vitamin D2 and vitamin D3 on intestinal calcium absorption in Nigerian children with rickets
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    J Clin Endocrinol Metab 94:3314-21. 2009
    ..Children with calcium-deficiency rickets have high 1,25-dihydroxyvitamin D values...
  10. pmc Maternal vitamin D supplementation to improve the vitamin D status of breast-fed infants: a randomized controlled trial
    Sara S Oberhelman
    Department of Family Medicine, Mayo Clinic, Rochester, MN Electronic address
    Mayo Clin Proc 88:1378-87. 2013
    ..To determine whether a single monthly supplement is as effective as a daily maternal supplement in increasing breast milk vitamin D to achieve vitamin D sufficiency in their infants...
  11. pmc Changing Incidence of Serum 25-Hydroxyvitamin D Values Above 50 ng/mL: A 10-Year Population-Based Study
    Daniel V Dudenkov
    Department of Internal Medicine, Mayo Clinic, Rochester, MN Electronic address
    Mayo Clin Proc 90:577-86. 2015
    ..To determine the incidence trend of 25-hydroxyvitamin D (25(OH)D) values above 50 ng/mL and associated toxicity...
  12. doi request reprint Bone mineral density in Nigerian children after discontinuation of calcium supplementation
    Puja J Umaretiya
    Mayo Medical School, Rochester, MN, USA
    Bone 55:64-8. 2013
    ..We therefore investigated the influence of prior calcium supplementation on forearm BMD 12 months after withdrawal of the supplement...
  13. doi request reprint Pediatric vitamin D and calcium nutrition in developing countries
    Philip R Fischer
    Department of Pediatric and Adolescent Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Rev Endocr Metab Disord 9:181-92. 2008
    ....
  14. doi request reprint Optimal Dose of Calcium for Treatment of Nutritional Rickets: A Randomized Controlled Trial
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, Rochester, MN, USA
    J Bone Miner Res 31:2024-2031. 2016
    ..Some children require longer than 24 weeks for complete healing of nutritional rickets. © 2016 American Society for Bone and Mineral Research...
  15. doi request reprint The effect of calcium supplementation on blood lead levels in Nigerian children
    Elizabeth M Keating
    Mayo Medical School, Rochester, MN, USA
    J Pediatr 159:845-850.e1. 2011
    ..To determine whether calcium supplementation alters the risk of lead toxicity...
  16. pmc CYP2R1 Mutations Impair Generation of 25-hydroxyvitamin D and Cause an Atypical Form of Vitamin D Deficiency
    Tom D Thacher
    Department of Family Medicine T D T, Jos University Teaching Hospital, Jos, Nigeria 930241 Department of Family Medicine T D T, Department of Pediatric and Adolescent Medicine P R F, and Department of Laboratory Medicine and Pathology R J S, Mayo Clinic, Rochester, Minnesota 55905 and The Children s Hospital of Philadelphia and Department of Pediatrics J R, M A L, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104
    J Clin Endocrinol Metab 100:E1005-13. 2015
    ..Production of the active vitamin D hormone 1,25-dihydroxyvitamin D requires hepatic 25-hydroxylation of vitamin D. The CYP2R1 gene encodes the principal vitamin D 25-hydroxylase in humans...
  17. doi request reprint The relationship of maternal bone density with nutritional rickets in Nigerian children
    Jennifer Hsu
    Mayo Medical School, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, United States Department of Pediatrics, Kaiser Permanente Oakland Medical Center, 3600 Broadway, Oakland, CA 94611, United States Electronic address
    Bone 97:216-221. 2017
    ..Nutritional rickets in Nigerian children was not associated with maternal forearm aBMD. Other unidentified maternal characteristics and practices likely contribute to the risk of rickets in Nigerian children...
  18. ncbi request reprint Nutritional rickets around the world: an update
    Ana L Creo
    a Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA
    Paediatr Int Child Health . 2016
    ....
  19. doi request reprint The effect of nutritional rickets on bone mineral density
    Tom D Thacher
    Department of Family Medicine T D T, Department of Pediatric and Adolescent Medicine P R F, Mayo Clinic, Rochester, Minnesota 55905 and MRC Wits Developmental Pathways for Health Research Unit J M P, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, Parktown 2193, South Africa
    J Clin Endocrinol Metab 99:4174-80. 2014
    ..Nutritional rickets is caused by impaired mineralization of growing bone. The effect of nutritional rickets on areal bone mineral density (aBMD) has not been established...
  20. pmc Vitamin D treatment in calcium-deficiency rickets: a randomised controlled trial
    Tom D Thacher
    Department of Family Medicine, Mayo Clinic, Rochester, Minnesota, USA
    Arch Dis Child 99:807-11. 2014
    ..To determine whether children with calcium-deficiency rickets have a better response to treatment with vitamin D and calcium than with calcium alone...
  21. doi request reprint The effect of an automated clinical reminder on weight loss in primary care
    Jason S O'Grady
    the Department of Family Medicine and the Division of Primary Care, Department of Internal Medicine, Mayo Clinic, Rochester, MN
    J Am Board Fam Med 26:745-50. 2013
    ....