Rodolfo Savica

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. doi Epidemiology of alpha-synucleinopathies: from Parkinson disease to dementia with Lewy bodies
    R Savica
    Department of Neurology, Mayo Clinic, Rochester, MN, USA Electronic address
    Handb Clin Neurol 138:153-8. 2016
  2. pmc High school football and risk of neurodegeneration: a community-based study
    Rodolfo Savica
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 87:335-40. 2012
  3. doi Parkinsonism and dropped head: dystonia, myopathy or both?
    Rodolfo Savica
    Department of Neurology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Parkinsonism Relat Disord 18:30-4. 2012
  4. pmc Prevention of dementia
    Rodolfo Savica
    Department of Neurology, Mayo Clinic, Gonda 8 South, 200 First Street SW, Rochester, MN 55905, USA
    Psychiatr Clin North Am 34:127-45. 2011
  5. pmc Incidence of dementia with Lewy bodies and Parkinson disease dementia
    Rodolfo Savica
    Department of Neurology, College of Medicine, Mayo Clinic, Rochester, Minnesota2Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, Minnesota
    JAMA Neurol 70:1396-402. 2013
  6. doi Cerebral Amyloid Deposition Is Associated with Gait Parameters in the Mayo Clinic Study of Aging
    Alexandra M V Wennberg
    Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota
    J Am Geriatr Soc . 2016
  7. pmc Plasma sphingolipid changes with autopsy-confirmed Lewy Body or Alzheimer's pathology
    Rodolfo Savica
    Department of Neurology, Mayo Clinic, Rochester, MN, 55905, USA Department of Health Sciences Research, Division of Epidemiology, Rochester, MN, 55905, USA
    Alzheimers Dement (Amst) 3:43-50. 2016
  8. pmc The GGGGCC repeat expansion in C9ORF72 in a case with discordant clinical and FDG-PET findings: PET trumps syndrome
    Anahita Adeli
    a Department of Neurology, Mayo Clinic, Rochester, Minnesota
    Neurocase 20:110-20. 2014
  9. pmc Incidence and pathology of synucleinopathies and tauopathies related to parkinsonism
    Rodolfo Savica
    Division of Epidemiology, Department of Health Science Research, College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    JAMA Neurol 70:859-66. 2013
  10. pmc Risk factors for Parkinson's disease may differ in men and women: an exploratory study
    Rodolfo Savica
    Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Horm Behav 63:308-14. 2013

Collaborators

Detail Information

Publications24

  1. doi Epidemiology of alpha-synucleinopathies: from Parkinson disease to dementia with Lewy bodies
    R Savica
    Department of Neurology, Mayo Clinic, Rochester, MN, USA Electronic address
    Handb Clin Neurol 138:153-8. 2016
    ..Studies of prevalence and incidence show increases with advancing age and a higher rate of Parkinson's disease and dementia with Lewy bodies in men compared to women. ..
  2. pmc High school football and risk of neurodegeneration: a community-based study
    Rodolfo Savica
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 87:335-40. 2012
    ..To assess whether high school football played between 1946 and 1956, when headgear was less protective than today, was associated with development of neurodegenerative diseases later in life...
  3. doi Parkinsonism and dropped head: dystonia, myopathy or both?
    Rodolfo Savica
    Department of Neurology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Parkinsonism Relat Disord 18:30-4. 2012
    ..The substrate for DHS is controversial, with some concluding that the cause is myopathic and others, exclusively dystonic. We report our clinical series of DHS arising in the setting of parkinsonism...
  4. pmc Prevention of dementia
    Rodolfo Savica
    Department of Neurology, Mayo Clinic, Gonda 8 South, 200 First Street SW, Rochester, MN 55905, USA
    Psychiatr Clin North Am 34:127-45. 2011
    ....
  5. pmc Incidence of dementia with Lewy bodies and Parkinson disease dementia
    Rodolfo Savica
    Department of Neurology, College of Medicine, Mayo Clinic, Rochester, Minnesota2Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, Minnesota
    JAMA Neurol 70:1396-402. 2013
    ..Epidemiologic data on dementia with Lewy bodies (DLB) and Parkinson disease dementia (PDD) remain limited in the United States and worldwide. These data are essential to guide research and clinical or public health interventions...
  6. doi Cerebral Amyloid Deposition Is Associated with Gait Parameters in the Mayo Clinic Study of Aging
    Alexandra M V Wennberg
    Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota
    J Am Geriatr Soc . 2016
    ..To determine the cross-sectional association between cerebral amyloid-beta (Aβ) deposition and gait...
  7. pmc Plasma sphingolipid changes with autopsy-confirmed Lewy Body or Alzheimer's pathology
    Rodolfo Savica
    Department of Neurology, Mayo Clinic, Rochester, MN, 55905, USA Department of Health Sciences Research, Division of Epidemiology, Rochester, MN, 55905, USA
    Alzheimers Dement (Amst) 3:43-50. 2016
    ..The clinical and pathological phenotypes of Dementia with Lewy Bodies (DLB) and Alzheimer's disease (AD) often overlap. We examined whether plasma lipids differed among individuals with autopsy-confirmed Lewy Body pathology or AD pathology...
  8. pmc The GGGGCC repeat expansion in C9ORF72 in a case with discordant clinical and FDG-PET findings: PET trumps syndrome
    Anahita Adeli
    a Department of Neurology, Mayo Clinic, Rochester, Minnesota
    Neurocase 20:110-20. 2014
    ....
  9. pmc Incidence and pathology of synucleinopathies and tauopathies related to parkinsonism
    Rodolfo Savica
    Division of Epidemiology, Department of Health Science Research, College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    JAMA Neurol 70:859-66. 2013
    ..The frequency and distribution of synucleinopathies and tauopathies manifesting with parkinsonism in the general population are poorly understood, thus affecting health care planning and research...
  10. pmc Risk factors for Parkinson's disease may differ in men and women: an exploratory study
    Rodolfo Savica
    Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Horm Behav 63:308-14. 2013
    ..By contrast, in women, anemia was the most important factor and we observed a suggestive synergistic interaction between anemia and higher education. Risk factors for PD and their interactions may differ in men and women...
  11. pmc Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study
    Michelle M Mielke
    From the Divisions of Epidemiology M M Mielke, R O R, R C P, Y E G and Biomedical Statistics and Informatics H J W, S D W, Department of Health Sciences Research Departments of Neurology R S, D S K, R O R, R C P, Psychiatry and Psychology M M Machulda, and Radiology P V, V J L, C R J, Mayo Clinic, Rochester, MN and Departments of Psychiatry, Psychology, and Neurology Y E G, Mayo Clinic, Scottsdale, AZ
    Neurology 82:70-6. 2014
    ..We determined whether head trauma was associated with amyloid deposition and neurodegeneration among individuals who were cognitively normal (CN) or had mild cognitive impairment (MCI)...
  12. pmc Comparison of Gait Parameters for Predicting Cognitive Decline: The Mayo Clinic Study of Aging
    Rodolfo Savica
    Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
    J Alzheimers Dis 55:559-567. 2017
    ..However, the predictive value of other gait parameters for cognitive decline is unclear...
  13. pmc Incidence and time trends of drug-induced parkinsonism: A 30-year population-based study
    Rodolfo Savica
    Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
    Mov Disord . 2016
    ..Epidemiological studies of drug-induced parkinsonism remain limited...
  14. pmc Time Trends in the Incidence of Parkinson Disease
    Rodolfo Savica
    Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota2Department of Neurology, Mayo Clinic, Rochester, Minnesota
    JAMA Neurol 73:981-9. 2016
    ..Changes over time in the incidence of parkinsonism and Parkinson disease (PD) remain uncertain...
  15. doi Deep brain stimulation in benign tremulous parkinsonism
    Rodolfo Savica
    Department of Neurology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Arch Neurol 68:1033-6. 2011
    ..This disorder has an uncertain pathophysiologic relationship to idiopathic Parkinson disease. Deep brain stimulation (DBS) should be efficacious for this condition, but there is no previously published experience...
  16. pmc Deep brain stimulation in tourette syndrome: a description of 3 patients with excellent outcome
    Rodolfo Savica
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 87:59-62. 2012
    ..At 1-year follow-up, the mean reduction in the total Yale Global Tic Severity Scale score in the 3 patients was 70% (range, 60%-80%).Our study further supports the role of the CM/Pf DBS target in medically intractable TS...
  17. pmc Plasma ceramide and glucosylceramide metabolism is altered in sporadic Parkinson's disease and associated with cognitive impairment: a pilot study
    Michelle M Mielke
    Departments of Health Science Research and Neurology, Mayo Clinic, Rochester, Minnesota, United States of America
    PLoS ONE 8:e73094. 2013
    ..We hypothesized that plasma levels of lipids involved in ceramide metabolism would also be altered in PD non-GBA mutation carriers and associated with worse cognition...
  18. doi Duration and Pathologic Correlates of Lewy Body Disease
    Jonathan Graff-Radford
    Department of Neurology, Mayo Clinic, Rochester, Minnesota
    JAMA Neurol . 2017
    ..Although patients with dementia with Lewy bodies (DLB) have shorter disease duration than patients with Alzheimer disease dementia, little is known about which factors influence disease duration among patients with DLB...
  19. doi Clinical and electrophysiologic variability in amyotrophic lateral sclerosis within a kindred harboring the C9ORF72 repeat expansion
    Elizabeth A Coon
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Amyotroph Lateral Scler Frontotemporal Degener 14:132-7. 2013
    ..In conclusion, this kindred demonstrates that the presentation of ALS within c9FTD/ALS families may vary considerably and electrophysiologic findings reflect this heterogeneity...
  20. pmc Metabolic markers or conditions preceding Parkinson's disease: a case-control study
    Rodolfo Savica
    Department of Neurology, College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Mov Disord 27:974-9. 2012
    ..77; 95% CI, 0.37-1.57; P = .47). Our study, based on historical information from a records-linkage system, does not support an association between BMI, cholesterol level, hypertension, or diabetes mellitus with later development of PD...
  21. doi Clinical failure of botulinum toxin A in movement disorders
    Rodolfo Savica
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Parkinsonism Relat Disord 18:73-5. 2012
    ..Botulinum toxin (BTX) injections have been used extensively in medicine; however, little is known about the factors predicting the loss of effectiveness of botulin toxin...
  22. ncbi The clinical spectrum and natural history of pure akinesia with gait freezing
    Emily Owens
    Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA
    J Neurol 263:2419-2423. 2016
    ..Bradykinesia, tremor, and rigidity do not develop, distinguishing pure akinesia with gait freezing from Parkinson's disease and other parkinsonian disorders...
  23. pmc A population-based study of the association between bullous pemphigoid and neurologic disorders
    Katherine E Brick
    Department of Dermatology, Mayo Clinic, Rochester, Minnesota
    J Am Acad Dermatol 71:1191-7. 2014
    ..Bullous pemphigoid (BP) has been associated with neurologic disorders...
  24. doi Ifosfamide associated myoclonus-encephalopathy syndrome
    Rodolfo Savica
    Department of Neurology, Division of Movement Disorders, Mayo Clinic, 200 1st Street S W, Rochester, MN 55905, USA
    J Neurol 258:1729-31. 2011
    ..Treatment with methylene blue may be further considered as useful to ameliorate the movement disorders...