Elaine W Yu
Affiliation: Massachusetts General Hospital
- Defects in cortical microarchitecture among African-American women with type 2 diabetesE W Yu
Endocrine Unit, Massachusetts General Hospital, 50 Blossom Street, THR 1051, Boston, MA, 02114, USA
Osteoporos Int 26:673-9. 2015..These cortical deficits are associated with hyperglycemia and may contribute to skeletal fragility associated with DM2...
- Simulated increases in body fat and errors in bone mineral density measurements by DXA and QCTElaine W Yu
Endocrine Unit, Massachusetts General Hospital, Boston, MA 02114, USA
J Bone Miner Res 27:119-24. 2012..Although overlying fat also affects QCT BMD measurements, the error is smaller and more uniform than with DXA BMD. Caution must be used when interpreting BMD changes in humans whose body composition is changing...
- Acid-suppressive medications and risk of bone loss and fracture in older adultsElaine W Yu
Endocrine Division, Massachusetts General Hospital, Thier 1101, 50 Blossom Street, Boston, MA 02114, USA
Calcif Tissue Int 83:251-9. 2008..The use of PPIs in older women, and perhaps older men with low calcium intake, may be associated with a modestly increased risk of nonspine fracture...
- Time-dependent changes in skeletal response to teriparatide: escalating vs. constant dose teriparatide (PTH 1-34) in osteoporotic womenElaine W Yu
Massachusetts General Hospital Department of Medicine, Endocrine Unit, Boston, MA 02114, USA
Bone 48:713-9. 2011..The time-dependent waning of the response to teriparatide appears to be bone-specific...
- Proton pump inhibitors and risk of fractures: a meta-analysis of 11 international studiesElaine W Yu
Endocrine Unit, Massachusetts General Hospital, Boston, USA
Am J Med 124:519-26. 2011..Concerns have been raised about the risk of fractures with acid-suppressive medications, such as proton pump inhibitors and histamine(2)-receptor antagonists...
- Acute decline in serum sclerostin in response to PTH infusion in healthy menElaine W Yu
Massachusetts General Hospital Endocrine Unit, 50 Blossom Street, Thier 1051, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 96:E1848-51. 2011..The immediate physiological changes in serum sclerostin in response to PTH infusion have not been reported in human studies...
- Differences in skeletal microarchitecture and strength in African-American and white womenMelissa S Putman
Endocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA Endocrine Division, Boston Children s Hospital, Boston, MA, USA
J Bone Miner Res 28:2177-85. 2013..In conclusion, differences in bone microarchitecture and density contribute to greater estimated bone strength in African-Americans and probably explain, at least in part, the lower fracture risk of African-American women...
- Two-year changes in bone density after Roux-en-Y gastric bypass surgeryElaine W Yu
Endocrine Unit E W Y, M L B, M S P, E L M, A E R, J S F, and Weight Center J S A P, W S B, Massachusetts General Hospital, Boston, Massachusetts 02114
J Clin Endocrinol Metab 100:1452-9. 2015..Bariatric surgery is increasingly popular but may lead to metabolic bone disease...
- Differences in Trabecular Microstructure between Black and White Women Assessed by Individual Trabecular Segmentation Analysis of HR-pQCT ImagesMelissa S Putman
Endocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114
J Bone Miner Res . 2016..These differences may contribute to the improved bone strength and lower fracture risk observed in Black women. This article is protected by copyright. All rights reserved...
- Teriparatide (PTH 1-34) treatment increases peripheral hematopoietic stem cells in postmenopausal womenElaine W Yu
Endocrine Unit, Massachusetts General Hospital, Boston, MA, USA
J Bone Miner Res 29:1380-6. 2014..This clinical study establishes the importance of PTH in the regulation of the HSC niche within humans. © 2014 American Society for Bone and Mineral Research. ..
- Bone loss after bariatric surgery: discordant results between DXA and QCT bone densityElaine W Yu
Department of Medicine, Endocrine Unit, Massachusetts General Hospital, Boston, MA, USA
J Bone Miner Res 29:542-50. 2014..These discordant results suggest that artifacts induced by large changes in body weight after bariatric surgery affect DXA and/or QCT measurements of bone, particularly at the hip...
- Gonadal steroids and body composition, strength, and sexual function in menJoel S Finkelstein
Endocrine Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
N Engl J Med 369:1011-22. 2013..Current approaches to diagnosing testosterone deficiency do not consider the physiological consequences of various testosterone levels or whether deficiencies of testosterone, estradiol, or both account for clinical manifestations...
- Association Between Insulin Resistance and Bone Structure in Nondiabetic Postmenopausal WomenVikram V Shanbhogue
Department of Endocrinology V V S, Odense University Hospital, Odense 5000 C, Denmark Endocrine Unit J S F, M L B, E W Y, Massachusetts General Hospital, Boston, Massachusetts 02114 and Center for Advanced Orthopedic Studies M L B, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215
J Clin Endocrinol Metab 101:3114-22. 2016..The clinical consequences of insulin resistance and hyperinsulinemia on bone remain largely unknown...
- Cortical and trabecular deterioration in mouse models of Roux-en-Y gastric bypassElaine W Yu
Endocrine Unit, Massachusetts General Hospital, USA
Bone 85:23-8. 2016..Future studies that exploit this murine model will help delineate the alterations in bone metabolism and mechanisms of bone loss after RYGB. ..