Daniel H Solomon

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Cardiovascular care and cancer screening in female nurses with and without rheumatoid arthritis
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Arthritis Rheum 51:429-32. 2004
  2. pmc Variation in the risk of suicide attempts and completed suicides by antidepressant agent in adults: a propensity score-adjusted analysis of 9 years' data
    Sebastian Schneeweiss
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Arch Gen Psychiatry 67:497-506. 2010
  3. pmc Variation in initial kidney replacement therapy for end-stage renal disease due to lupus nephritis in the United States
    Amy Devlin
    Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    Arthritis Care Res (Hoboken) 63:1642-53. 2011
  4. ncbi request reprint Immunosuppressive medications and hospitalization for cardiovascular events in patients with rheumatoid arthritis
    Daniel H Solomon
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Arthritis Rheum 54:3790-8. 2006
  5. doi request reprint Heart failure risk among patients with rheumatoid arthritis starting a TNF antagonist
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Ann Rheum Dis 72:1813-8. 2013
  6. pmc Epidemiology and sociodemographics of systemic lupus erythematosus and lupus nephritis among US adults with Medicaid coverage, 2000-2004
    Candace H Feldman
    Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Arthritis Rheum 65:753-63. 2013
  7. ncbi request reprint Performance of a rheumatoid arthritis records-based index of severity
    Gladys Ting
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    J Rheumatol 32:1679-87. 2005
  8. pmc Biologic discontinuation studies: a systematic review of methods
    Kazuki Yoshida
    Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Ann Rheum Dis 73:595-9. 2014
  9. pmc Pain persists in DAS28 rheumatoid arthritis remission but not in ACR/EULAR remission: a longitudinal observational study
    Yvonne C Lee
    Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, 75 Francis Street, PBB B3, Boston, MA, USA
    Arthritis Res Ther 13:R83. 2011
  10. pmc Tumor necrosis factor-alpha antagonist use and heart failure in elderly patients with rheumatoid arthritis
    Soko Setoguchi
    Divisions of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard MedicalSchool, Boston, MA 02130, USA
    Am Heart J 156:336-41. 2008

Detail Information

Publications129 found, 100 shown here

  1. ncbi request reprint Cardiovascular care and cancer screening in female nurses with and without rheumatoid arthritis
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Arthritis Rheum 51:429-32. 2004
    ..To compare frequencies of cancer screening and cardiovascular treatments aimed at reducing acute myocardial infarction in women with and without rheumatoid arthritis (RA)...
  2. pmc Variation in the risk of suicide attempts and completed suicides by antidepressant agent in adults: a propensity score-adjusted analysis of 9 years' data
    Sebastian Schneeweiss
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Arch Gen Psychiatry 67:497-506. 2010
    ..This prompted a meta-analysis of trials in adults that found no overall increase in risk, but individual agents could not be studied...
  3. pmc Variation in initial kidney replacement therapy for end-stage renal disease due to lupus nephritis in the United States
    Amy Devlin
    Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    Arthritis Care Res (Hoboken) 63:1642-53. 2011
    ..We aimed to identify sociodemographic and clinical factors associated with variation in initial kidney replacement therapies among LN ESRD patients...
  4. ncbi request reprint Immunosuppressive medications and hospitalization for cardiovascular events in patients with rheumatoid arthritis
    Daniel H Solomon
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Arthritis Rheum 54:3790-8. 2006
    ..This study was undertaken to investigate the effects of various immunosuppressive medications on the risk of cardiovascular events among a group of older patients with RA...
  5. doi request reprint Heart failure risk among patients with rheumatoid arthritis starting a TNF antagonist
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Ann Rheum Dis 72:1813-8. 2013
    ..We studied the risk of new or recurrent HF among a group of patients receiving these agents to treat rheumatoid arthritis (RA)...
  6. pmc Epidemiology and sociodemographics of systemic lupus erythematosus and lupus nephritis among US adults with Medicaid coverage, 2000-2004
    Candace H Feldman
    Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Arthritis Rheum 65:753-63. 2013
    ..This study was undertaken to investigate the epidemiology and sociodemographics of SLE and LN in the low-income US Medicaid population...
  7. ncbi request reprint Performance of a rheumatoid arthritis records-based index of severity
    Gladys Ting
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    J Rheumatol 32:1679-87. 2005
    ..To assess the performance of a rheumatoid arthritis (RA) records-based index of severity (RARBIS) developed by a Delphi panel process in a cohort of patients with RA...
  8. pmc Biologic discontinuation studies: a systematic review of methods
    Kazuki Yoshida
    Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Ann Rheum Dis 73:595-9. 2014
    ..We conducted a systematic review to assess the design and 'failure definition' in studies of biologic discontinuation in rheumatoid arthritis (RA)...
  9. pmc Pain persists in DAS28 rheumatoid arthritis remission but not in ACR/EULAR remission: a longitudinal observational study
    Yvonne C Lee
    Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, 75 Francis Street, PBB B3, Boston, MA, USA
    Arthritis Res Ther 13:R83. 2011
    ..We assessed the prevalence of pain in RA patients in remission according to the Disease Activity Score (DAS28-CRP4) and the American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) remission criteria...
  10. pmc Tumor necrosis factor-alpha antagonist use and heart failure in elderly patients with rheumatoid arthritis
    Soko Setoguchi
    Divisions of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard MedicalSchool, Boston, MA 02130, USA
    Am Heart J 156:336-41. 2008
    ..Although TNFAs had significant benefits in treating rheumatoid arthritis (RA), little is known whether the drugs pose an increased risk of HF in older patients with RA...
  11. ncbi request reprint Osteoporosis management in patients with rheumatoid arthritis: Evidence for improvement
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Arthritis Rheum 55:873-7. 2006
    ..The goal was to examine the frequency of osteoporosis management in patients with RA treated at a large academic rheumatology practice...
  12. doi request reprint The comparative safety of opioids for nonmalignant pain in older adults
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Arch Intern Med 170:1979-86. 2010
    ..However, there is relatively little information about the comparative safety of opioids. Therefore, we sought to compare the safety of opioids commonly used for nonmalignant pain...
  13. ncbi request reprint Simultaneous assessment of short-term gastrointestinal benefits and cardiovascular risks of selective cyclooxygenase 2 inhibitors and nonselective nonsteroidal antiinflammatory drugs: an instrumental variable analysis
    Sebastian Schneeweiss
    Harvard Medical School, Division of Pharmacoepidemiology and Pharmacoeconomics, Boston, MA 021205, USA
    Arthritis Rheum 54:3390-8. 2006
    ....
  14. ncbi request reprint Anti-tumor necrosis factor alpha therapy and the risk of serious bacterial infections in elderly patients with rheumatoid arthritis
    Sebastian Schneeweiss
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Arthritis Rheum 56:1754-64. 2007
    ..To assess the association between the initiation of anti-tumor necrosis factor alpha (anti-TNFalpha) therapy and the risk of serious bacterial infections in routine care...
  15. ncbi request reprint Relationship between COX-2 specific inhibitors and hypertension
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02120, USA
    Hypertension 44:140-5. 2004
    ..1; 95% CI, 1.0 to 4.3). In this retrospective case-control study of patients aged > or =65 years, rofecoxib use was associated with an increased relative risk of new onset hypertension; this was not seen in patients taking celecoxib...
  16. pmc The relationship between focal erosions and generalized osteoporosis in postmenopausal women with rheumatoid arthritis
    Daniel H Solomon
    Brigham and Women s Hospital, Division of Rheumatology, Boston, Massachusetts 02115, USA
    Arthritis Rheum 60:1624-31. 2009
    ..The aim of this study was to determine whether lower BMD is associated with higher erosion scores among patients with RA...
  17. pmc Subgroup analyses to determine cardiovascular risk associated with nonsteroidal antiinflammatory drugs and coxibs in specific patient groups
    Daniel H Solomon
    Brigham and Women s Hospital, 1620 Tremont Street, Boston, MA 02120, USA
    Arthritis Rheum 59:1097-104. 2008
    ..There is substantial concern regarding the potential cardiovascular adverse effects of selective coxibs and nonselective NSAIDs, but many patients with arthritis experience important clinical benefits from these agents...
  18. pmc High-risk patients' readiness to undergo BMD testing for osteoporosis diagnosis in Pennsylvania
    Jennifer M Polinski
    Brigham and Women s Hospital, Boston, Massachusetts, USA
    Int Q Community Health Educ 29:223-40. 2008
    ..We found several correlates of readiness to undergo BMD screening that may be used to design effective interventions...
  19. pmc Cardiovascular risk in rheumatoid arthritis: comparing TNF-α blockade with nonbiologic DMARDs
    Daniel H Solomon
    Brigham and Women s Hospital, Boston, MA 02115, USA
    Am J Med 126:730.e9-730.e17. 2013
    ..We compared the cardiovascular risk in rheumatoid arthritis patients starting a TNF-α blocking agent versus a nonbiologic disease-modifying antirheumatic drug (nbDMARD)...
  20. doi request reprint The comparative safety of analgesics in older adults with arthritis
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Arch Intern Med 170:1968-76. 2010
    ..The safety of alternative analgesics is unclear. We examined the comparative safety of nonselective NSAIDs (nsNSAIDs), selective cyclooxygenase 2 inhibitors (coxibs), and opioids...
  21. ncbi request reprint Compliance with osteoporosis medications
    Daniel H Solomon
    Divisions of Pharmacoepidemiology, Brigham and Women s Hospital, Boston, MA 02120, USA
    Arch Intern Med 165:2414-9. 2005
    ..This study was undertaken to assess the level and determinants of compliance with drugs prescribed for osteoporosis...
  22. pmc Trends in the incidence, demographics, and outcomes of end-stage renal disease due to lupus nephritis in the US from 1995 to 2006
    Karen H Costenbader
    Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Arthritis Rheum 63:1681-8. 2011
    ....
  23. doi request reprint Association between disease-modifying antirheumatic drugs and diabetes risk in patients with rheumatoid arthritis and psoriasis
    Daniel H Solomon
    Division of Pharmacoepidemiology, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    JAMA 305:2525-31. 2011
    ..Rheumatoid arthritis (RA) and psoriasis have been linked with insulin resistance and diabetes mellitus (DM). Prior investigations suggest that systemic immunosuppressive drugs may improve insulin resistance and reduce the risk of DM...
  24. pmc Relative effectiveness of osteoporosis drugs for preventing nonvertebral fracture
    Suzanne M Cadarette
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, and Boston University, Boston, Massachusetts 02120, USA
    Ann Intern Med 148:637-46. 2008
    ..Little information is available on the comparative effectiveness of osteoporosis pharmacotherapies...
  25. pmc Performance of matrix-based risk models for rapid radiographic progression in a cohort of patients with established rheumatoid arthritis
    Siri Lillegraven
    Brigham and Women s Hospital, Boston, Massachusetts Diakonhjemmet Hospital, Oslo, Norway
    Arthritis Care Res (Hoboken) 65:526-33. 2013
    ..We tested the performance of 3 risk models for RRP in an observational cohort...
  26. doi request reprint Increasing pneumococcal vaccination for immunosuppressed patients: a cluster quality improvement trial
    Sonali P Desai
    Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Arthritis Rheum 65:39-47. 2013
    ....
  27. doi request reprint The impact of reducing cardiovascular medication copayments on health spending and resource utilization
    Niteesh K Choudhry
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
    J Am Coll Cardiol 60:1817-24. 2012
    ..The aim of this study was to evaluate the impact of reductions in statin and clopidogrel copayments on cardiovascular resource utilization, major coronary events, and insurer spending...
  28. pmc Hand bone mineral density is associated with both total hip and lumbar spine bone mineral density in post-menopausal women with RA
    Sonali P Desai
    Brigham and Women s Hospital, PBB B3, Boston, MA 02115, USA
    Rheumatology (Oxford) 49:513-9. 2010
    ..RA is associated with localized bone loss in the hands, as well as generalized osteoporosis. We evaluated the relationship between hand digital X-ray radiogrammetry BMD (DXR-BMD) and total hip and lumbar spine BMD...
  29. pmc The complex relation between bisphosphonate adherence and fracture reduction
    Amanda R Patrick
    Divisions of Pharmacoepidemiology and Pharmacoeconomics Department of Medicine, Brigham and Women s Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
    J Clin Endocrinol Metab 95:3251-9. 2010
    ....
  30. ncbi request reprint Relationship between selective cyclooxygenase-2 inhibitors and acute myocardial infarction in older adults
    Daniel H Solomon
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont St, Suite 3030, Boston, Mass 02120, USA
    Circulation 109:2068-73. 2004
    ..We studied the relative risk of acute myocardial infarction (AMI) among users of celecoxib, rofecoxib, and NSAIDs in Medicare beneficiaries with a comprehensive drug benefit...
  31. pmc The association between statin use and outcomes potentially attributable to an unhealthy lifestyle in older adults
    Amanda R Patrick
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Value Health 14:513-20. 2011
    ..To explore the "healthy user" and "healthy adherer" effects-hypothetical sources of bias thought to arise when patients who initiate and adhere to preventive therapies are more likely to engage in healthy behaviors than are other subjects...
  32. pmc End-stage renal disease due to lupus nephritis among children in the US, 1995-2006
    Linda T Hiraki
    Harvard School of Public Health and Brigham and Women s Hospital, Boston, Massachusetts, USA
    Arthritis Rheum 63:1988-97. 2011
    ..To identify predictors of wait-listing for kidney transplantation, kidney transplantation, and mortality among children with lupus nephritis-associated end-stage renal disease (ESRD)...
  33. pmc Can improved prescription medication labeling influence adherence to chronic medications? An evaluation of the Target pharmacy label
    William H Shrank
    Department of Medicine, Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street Suite 3030, Boston, MA 02120, USA
    J Gen Intern Med 24:570-8. 2009
    ..A new prescription medication labeling system was implemented by Target pharmacies in May 2005 and aimed to improve readability and understanding...
  34. ncbi request reprint Explained variation in a model of therapeutic decision making is partitioned across patient, physician, and clinic factors
    M Alan Brookhart
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
    J Clin Epidemiol 59:18-25. 2006
    ..A statistical method is presented for attributing explained variation in patient care to different levels of aggregation in a multilevel model with the aim of prioritizing and targeting quality improvement interventions...
  35. pmc Comparative risk of fracture in men and women with HIV
    Lydia Gedmintas
    Division of Rheumatology L G, E L, J N K, D H S, Immunology, and Allergy, Brigham and Women s Hospital, Boston, Massachusetts 02115 Orthopedic and Arthritis Center for Outcomes Research E A W, E L, J N K, Department of Orthopedic Surgery, Brigham and Women s Hospital, Boston, Massachusetts 02115 Department of Biostatistics E L, Boston University School of Public Health, Boston, Massachusetts 02118 Harvard Medical School E L, J N K, D H S, Boston, Massachusetts 02115 and Division of Pharmacoepidemiology and Pharmacoeconomics D H S, Brigham and Women s Hospital, Boston, Massachusetts 02115
    J Clin Endocrinol Metab 99:486-90. 2014
    ..Men and women with HIV have an increased risk of fracture compared with individuals without HIV; however, it is unknown if women with HIV fracture at higher rates than men...
  36. pmc Incidence and predictors of secondary fibromyalgia in an early arthritis cohort
    Yvonne C Lee
    Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Ann Rheum Dis 72:949-54. 2013
    ..The authors examined the incidence of secondary FM in an early inflammatory arthritis cohort, and assessed the association between pain, inflammation, psychosocial variables and the clinical diagnosis of FM...
  37. pmc Osteoporosis telephonic intervention to improve medication regimen adherence: a large, pragmatic, randomized controlled trial
    Daniel H Solomon
    Division of Rheumatology, Immunology, and Allergy, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    Arch Intern Med 172:477-83. 2012
    ..We examined the effectiveness of a telephone-based counseling program rooted in motivational interviewing to improve adherence to a medication regimen for osteoporosis...
  38. doi request reprint Remission and radiographic outcome in rheumatoid arthritis: application of the 2011 ACR/EULAR remission criteria in an observational cohort
    Siri Lillegraven
    Division of Rheumatology Section of Clinical Sciences, Alumnae Hall Room 305, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Ann Rheum Dis 71:681-6. 2012
    ....
  39. doi request reprint Percutaneous vertebroplasty among low income Medicare beneficiaries
    Daniel H Solomon
    Divisions of Pharmacoepidemiology, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
    Spine (Phila Pa 1976) 32:2910-4. 2007
    ..Cohort...
  40. ncbi request reprint The medical license number accurately identifies the prescribing physician in a large pharmacy claims database
    M Alan Brookhart
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Med Care 45:907-10. 2007
    ..We studied the accuracy of the medical license number in data from a state-run drug benefit plan by assessing its consistency with 2 external sources of data...
  41. ncbi request reprint Adherence to lipid-lowering therapy and the use of preventive health services: an investigation of the healthy user effect
    M Alan Brookhart
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital Harvard Medical School, Boston, MA 02120, USA
    Am J Epidemiol 166:348-54. 2007
    ..Further work is needed to identify study design and analysis methods that can be used to minimize the healthy user bias in studies of preventive therapies...
  42. doi request reprint Gender differences in the management and prognosis of myocardial infarction among patients > or = 65 years of age
    Soko Setoguchi
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 101:1531-6. 2008
    ..Men, especially those aged > or =75 years, however, had worse short- and long-term prognoses compared with women of a similar age. The mortality was highest and the gender effect was more pronounced during the MI hospitalizations...
  43. pmc Development of a health care utilisation data-based index for rheumatoid arthritis severity: a preliminary study
    Gladys Ting
    Department of Medicine, Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Arthritis Res Ther 10:R95. 2008
    ....
  44. ncbi request reprint Tumor necrosis factor alpha antagonist use and cancer in patients with rheumatoid arthritis
    Soko Setoguchi
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02130, USA
    Arthritis Rheum 54:2757-64. 2006
    ..This study was undertaken to estimate the association between treatment with biologic disease-modifying antirheumatic drugs (DMARDs) and development of cancer in patients with RA...
  45. ncbi request reprint Prescription opioid use among older adults with arthritis or low back pain
    Daniel H Solomon
    Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Ste, 3030, Boston, MA 02120, USA
    Arthritis Rheum 55:35-41. 2006
    ..To examine patterns of chronic opioid use in selected groups with arthritis and low back pain and compare them with patterns among persons with ischemic heart disease...
  46. pmc Sustained rheumatoid arthritis remission is uncommon in clinical practice
    Femke H M Prince
    Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Arthritis Res Ther 14:R68. 2012
    ..Remission is an important goal of therapy in rheumatoid arthritis (RA), but data on duration of remission are lacking. Our objective was to describe the duration of remission in RA, assessed by different criteria...
  47. pmc Supplementing claims data with outpatient laboratory test results to improve confounding adjustment in effectiveness studies of lipid-lowering treatments
    Sebastian Schneeweiss
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
    BMC Med Res Methodol 12:180. 2012
    ..Adjusting for laboratory test results may result in better confounding control when added to administrative claims data in the study of treatment effects. However, missing values can arise through several mechanisms...
  48. pmc Adipokine hormones and hand osteoarthritis: radiographic severity and pain
    Mei Massengale
    Division of Rheumatology, Immunology, and Allergy, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 7:e47860. 2012
    ..Obesity's association with hand osteoarthritis cannot be fully explained by mechanical loading. We examined the relationship between adipokines and radiographic hand osteoarthritis severity and pain...
  49. pmc Validation of rheumatoid arthritis diagnoses in health care utilization data
    Seo Young Kim
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Arthritis Res Ther 13:R32. 2011
    ..Health care utilization databases have been increasingly used for studies of rheumatoid arthritis (RA). However, the accuracy of RA diagnoses in these data has been inconsistent...
  50. ncbi request reprint Agreement of diagnosis and its date for hematologic malignancies and solid tumors between medicare claims and cancer registry data
    Soko Setoguchi
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Cancer Causes Control 18:561-9. 2007
    ..However, linkage between cancer registry and claims data including pharmacy-dispensing information is not always available. We examined the accuracy of claims-based definitions of incident cancers and their date of diagnosis...
  51. ncbi request reprint Osteoporosis improvement: a large-scale randomized controlled trial of patient and primary care physician education
    Daniel H Solomon
    Division of Pharmacoepidemiology, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    J Bone Miner Res 22:1808-15. 2007
    ..04; 95% ci, 0.85-1.26)...
  52. doi request reprint Using genetic and clinical data to understand response to disease-modifying anti-rheumatic drug therapy: data from the Brigham and Women's Hospital Rheumatoid Arthritis Sequential Study
    Christine K Iannaccone
    Department of Medicine, Brigham and Women s Hospital, PBB B3, 75 Francis Street, Boston, MA 02115, USA
    Rheumatology (Oxford) 50:40-6. 2011
    ....
  53. pmc Adherence to osteoporosis medications after patient and physician brief education: post hoc analysis of a randomized controlled trial
    Aimee Der Huey Shu
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, MA 02115, USA
    Am J Manag Care 15:417-24. 2009
    ..To examine whether adherence to osteoporosis medications can be improved by educational interventions targeted at primary care physicians (PCPs) and patients...
  54. pmc Rationale and design of the Study Assessing the Effect of Cardiovascular Medications Provided as Low-cost, Evidence-based Generic Samples (SAMPLES) trial
    William H Shrank
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Am Heart J 157:613-9. 2009
    ..Highly effective generic cardiovascular medications are frequently underused, leading to greater overall drug costs and cost-related nonadherence...
  55. ncbi request reprint Physician follow-up and provider continuity are associated with long-term medication adherence: a study of the dynamics of statin use
    M Alan Brookhart
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
    Arch Intern Med 167:847-52. 2007
    ....
  56. pmc Accuracy of identifying neutropenia diagnoses in outpatient claims data
    Seo Young Kim
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 20:709-13. 2011
    ..We examined the validity and accuracy of claims-based algorithms to identify neutropenia from outpatient visits...
  57. pmc Oral bisphosphonates and risk of subtrochanteric or diaphyseal femur fractures in a population-based cohort
    Seo Young Kim
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Boston, MA, USA
    J Bone Miner Res 26:993-1001. 2011
    ..However, this study cannot exclude the possibility that long-term bisphosphonate use may increase the risk of these fractures...
  58. pmc Clinical predictors of erosion-free status in rheumatoid arthritis: a prospective cohort study
    Katherine P Liao
    Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, Boston, MA 02115, USA
    Rheumatology (Oxford) 50:1473-9. 2011
    ..Our objective was to characterize the group of RA patients without erosions and identify its clinical predictors...
  59. pmc Prior authorization for biologic disease-modifying antirheumatic drugs: a description of US Medicaid programs
    Michael A Fischer
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Arthritis Rheum 59:1611-7. 2008
    ..To evaluate state Medicaid prior authorization programs for biologic disease-modifying antirheumatic drugs (DMARDs)...
  60. ncbi request reprint Osteoporosis action: design of the healthy bones project trial
    Daniel H Solomon
    Division of Pharmacoepidemiology, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA, USA
    Contemp Clin Trials 26:78-94. 2005
    ..All outcomes will be analyzed using random effects models accounting for clustering of subjects within physicians' practices...
  61. pmc Impact of obesity and knee osteoarthritis on morbidity and mortality in older Americans
    Elena Losina
    Brigham and Women s Hospital, Boston University School of Public Health, Massachusetts General Hospital, USA
    Ann Intern Med 154:217-26. 2011
    ..Obesity and knee osteoarthritis are among the most frequent chronic conditions affecting Americans aged 50 to 84 years...
  62. pmc Hydroxychloroquine improves insulin sensitivity in obese non-diabetic individuals
    Emileigh Mercer
    Division of Rheumatology, Brigham and Women s Hospital Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Arthritis Res Ther 14:R135. 2012
    ..To investigate the mechanism of this effect, we examined the effect of HCQ on insulin resistance, insulin sensitivity, and pancreatic β-cell secretion of insulin in non-diabetic, obese subjects...
  63. pmc New loop diuretic prescriptions may be an acute risk factor for falls in the nursing home
    Sarah D Berry
    Hebrew SeniorLife Institute for Aging Research and Beth Israel Deaconess Medical Center Division of Gerontology, Boston, MA 02131, USA
    Pharmacoepidemiol Drug Saf 21:560-3. 2012
    ..We evaluated the relationship between change in a diuretic prescription (new prescription or increased dose) and the occurrence of documented falls among nursing home residents...
  64. pmc A comparison of statistical approaches for physician-randomized trials with survival outcomes
    Margaret R Stedman
    Orthopedics and Arthritis Center for Outcomes Research, Department of Orthopedics, Brigham and Women s Hospital, Boston, MA 02115, USA
    Contemp Clin Trials 33:104-15. 2012
    ..The marginal proportional hazards method performed well even when model assumptions were violated. Nonlinear mixed models were only advantageous when the distribution was correctly specified...
  65. ncbi request reprint A Medicare database review found that physician preferences increasingly outweighed patient characteristics as determinants of first-time prescriptions for COX-2 inhibitors
    Sebastian Schneeweiss
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
    J Clin Epidemiol 58:98-102. 2005
    ..We sought to quantify the relative contributions of patient vs. physician factors to the decision to prescribe selective cyclooxygenase-2 (COX-2) inhibitors during the first 2 years of their availability...
  66. pmc Confounder summary scores when comparing the effects of multiple drug exposures
    Suzanne M Cadarette
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 19:2-9. 2010
    ..We compared three analytic strategies to control for confounding based on measured variables: conventional multivariable, exposure propensity score (EPS), and disease risk score (DRS)...
  67. doi request reprint NSAID switching and short-term gastrointestinal outcome rates after the withdrawal of rofecoxib
    Sebastian Schneeweiss
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Boston, MA 021205, USA
    Pharmacoepidemiol Drug Saf 18:1134-42. 2009
    ....
  68. pmc Validity of self-report of infections in a longitudinal cohort of patients with rheumatoid arthritis differs by source of report and infection severity
    Julia F Simard
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    J Clin Epidemiol 63:1358-62. 2010
    ..We evaluated and compared the validity of patients' and rheumatologists' reports of infection with those confirmed by medical record review...
  69. ncbi request reprint Cardiovascular risk factors in women with and without rheumatoid arthritis
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Boston, MA 02120, USA
    Arthritis Rheum 50:3444-9. 2004
    ..The risk of cardiovascular disease (CVD) is increased in patients with rheumatoid arthritis (RA). The objective of this study was to examine the distribution of known CVD risk factors and biomarkers of CVD in women with and without RA...
  70. pmc Evaluating short-term drug effects using a physician-specific prescribing preference as an instrumental variable
    M Alan Brookhart
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital Harvard Medical School, Boston, MA 02120, USA
    Epidemiology 17:268-75. 2006
    ..Instrumental variable methods have been proposed as a potential approach to control confounding by indication in nonexperimental studies of treatment effects; however, good instruments are hard to find...
  71. pmc Predictors of discontinuation of tumor necrosis factor inhibitors in patients with rheumatoid arthritis
    Sandeep K Agarwal
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Rheumatol 35:1737-44. 2008
    ..Our goal was to determine the discontinuation rate of TNF inhibitors and identify predictors associated with discontinuation...
  72. ncbi request reprint Prior authorization policies for selective cyclooxygenase-2 inhibitors in Medicaid: a policy review
    Michael A Fischer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Boston, MA 02120, USA
    Med Care 44:658-63. 2006
    ..However, the evidence base for the prior authorization criteria has not been examined previously...
  73. ncbi request reprint Cardiovascular outcomes in new users of coxibs and nonsteroidal antiinflammatory drugs: high-risk subgroups and time course of risk
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Boston, Massachusetts 02120, USA
    Arthritis Rheum 54:1378-89. 2006
    ..This study was undertaken to examine, in a large group of new users of coxibs and NSAIDs, the rate of cardiovascular events, their time course, and whether baseline cardiovascular risk modified the rate ratios (RRs) for future events...
  74. pmc Improving care of patients at-risk for osteoporosis: a randomized controlled trial
    Daniel H Solomon
    Division of Pharmacepidemiology, Brigham and Women s Hospital, Boston, MA 02120, USA
    J Gen Intern Med 22:362-7. 2007
    ..We tested the effectiveness of an intervention to improve care in patients at-risk of osteoporosis...
  75. ncbi request reprint Determinants of selective cyclooxygenase-2 inhibitor prescribing: are patient or physician characteristics more important?
    Daniel H Solomon
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Med 115:715-20. 2003
    ..We examined the relative effects of patient risk factors for gastrointestinal toxicity, other patient characteristics, and physician prescribing preferences on the decision to prescribe a selective COX-2 inhibitor...
  76. pmc The validity of a rheumatoid arthritis medical records-based index of severity compared with the DAS28
    Masayo Sato
    Division of Pharmacoepidemiology, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
    Arthritis Res Ther 8:R57. 2006
    ..The RARBIS has both face and convergent validity for patients with RA and relevant subgroups and may have application for medical records studies in patients with RA...
  77. ncbi request reprint Identification of individuals with CKD from Medicare claims data: a validation study
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Am J Kidney Dis 46:225-32. 2005
    ..The validity of this approach to identify patients with CKD has not been sufficiently studied...
  78. ncbi request reprint Design of cluster-randomized trials of quality improvement interventions aimed at medical care providers
    Robert J Glynn
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
    Med Care 45:S38-43. 2007
    ..Such trials are frequently embedded in health care systems with available automated records, which can be used to enhance the design of the trial...
  79. pmc Correlations of nursing home characteristics with prescription of osteoporosis medications
    Seema Parikh
    Harvard Medical School, Boston, MA, USA
    Bone 48:1164-8. 2011
    ..NH characteristics have been associated with prescription of some medications. We examined associations of NH-level characteristics with osteoporosis treatment in elderly patients admitted to a NH after a fracture...
  80. pmc A cohort study of thiazolidinediones and fractures in older adults with diabetes
    Daniel H Solomon
    Division of Rheumatology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    J Clin Endocrinol Metab 94:2792-8. 2009
    ..Recent results from several randomized controlled trials find an increased risk of fracture with TZDs compared with other oral antidiabetic agents...
  81. pmc Opioid analgesics and the risk of fractures in older adults with arthritis
    Matthew Miller
    Department of Health Policy and Management, Harvard School of Public Health, Boston, Massachusetts, USA
    J Am Geriatr Soc 59:430-8. 2011
    ..To compare the risk of fracture associated with initiating opioids with that of nonsteroidal anti-inflammatory drugs (NSAIDs) and the variation in risk according to opioid dose, duration of action, and duration of use...
  82. ncbi request reprint Medication use patterns for osteoporosis: an assessment of guidelines, treatment rates, and quality improvement interventions
    Daniel H Solomon
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02120, USA
    Mayo Clin Proc 80:194-202. 2005
    ..To assess current osteoporosis treatment guidelines, studies of osteoporosis treatment, and interventions to improve osteoporosis treatment...
  83. ncbi request reprint Economic consequences of routine coronary angiography in low- and intermediate-risk patients with unstable angina pectoris
    Akshay S Desai
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Am J Cardiol 92:363-7. 2003
    ....
  84. ncbi request reprint Veteran's affairs hospital discharge databases coded serious bacterial infections accurately
    Sebastian Schneeweiss
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    J Clin Epidemiol 60:397-409. 2007
    ..We sought to test the ability of large health care utilization databases to accurately identify serious bacterial infections and opportunistic infections leading to hospital admission...
  85. ncbi request reprint Self-management education programs in chronic disease: a systematic review and methodological critique of the literature
    Asra Warsi
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02120, USA
    Arch Intern Med 164:1641-9. 2004
    ..We evaluated the efficacy of patient self-management educational programs for chronic diseases and critically reviewed their methodology...
  86. ncbi request reprint Adjusting for unmeasured confounders in pharmacoepidemiologic claims data using external information: the example of COX2 inhibitors and myocardial infarction
    Sebastian Schneeweiss
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Epidemiology 16:17-24. 2005
    ..We show how to assess the impact of confounding by factors not measured in Medicare claims data in a study of the association between selective COX2 inhibitors and acute myocardial infarction (MI)...
  87. ncbi request reprint Underuse of osteoporosis medications in elderly patients with fractures
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Boston, Massachusetts 02120, USA
    Am J Med 115:398-400. 2003
  88. ncbi request reprint Lipid levels and bone mineral density
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02120, USA
    Am J Med 118:1414. 2005
    ..The aim of this study was to examine the relationship between lipid levels and bone mineral density...
  89. ncbi request reprint Conversion from intravenous to oral medications: assessment of a computerized intervention for hospitalized patients
    Michael A Fischer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Departments of Medicine and Emergency Medicine, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
    Arch Intern Med 163:2585-9. 2003
    ..We examined the effect of a computer-based intervention to prompt physicians to switch appropriate patients from intravenous to oral medications...
  90. ncbi request reprint Does self-management education benefit all populations with arthritis? A randomized controlled trial in a primary care physician network
    Daniel H Solomon
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Rheumatol 29:362-8. 2002
    ..We conducted a randomized controlled trial of the ASMP course in a large primary care physician network...
  91. ncbi request reprint The hidden cost of nonselective nonsteroidal antiinflammatory drugs in older patients
    Daniel H Solomon
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Rheumatol 30:792-8. 2003
    ..We calculated the excess risk and costs associated with the major adverse effects of prescription nonselective NSAID...
  92. ncbi request reprint Nonsteroidal anti-inflammatory drug use and acute myocardial infarction
    Daniel H Solomon
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Arch Intern Med 162:1099-104. 2002
    ..Although aspirin has been shown to protect patients from acute myocardial infarction (AMI), the effect of nonaspirin nonsteroidal anti-inflammatory drugs (NSAIDs) is not clear...
  93. ncbi request reprint Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis
    Daniel H Solomon
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    Circulation 107:1303-7. 2003
    ..Rheumatoid arthritis may be associated with an increased risk of cardiovascular disease. We compared the incidence rates of myocardial infarction and stroke in subjects with and without rheumatoid arthritis...
  94. ncbi request reprint Which patients with knee problems are likely to benefit from nonarthroplasty surgery? Development of a clinical prediction rule
    Daniel H Solomon
    Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Arch Intern Med 164:509-13. 2004
    ..We examined factors associated with the clinical presentation of patients judged likely by orthopedic surgeons to benefit from nonarthroplasty knee surgery...
  95. ncbi request reprint Pharmacoepidemiology and rheumatic diseases: 2001-2002
    Daniel H Solomon
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Curr Opin Rheumatol 15:122-6. 2003
    ....
  96. pmc A SAS macro for a clustered permutation test
    Margaret R Stedman
    Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States
    Comput Methods Programs Biomed 95:89-94. 2009
    ..We describe a flexible and efficient SAS macro that implements the 2-sample clustered permutation test. We discuss the theory and applications behind this test as well as details of the SAS code...
  97. pmc Alcohol consumption and markers of inflammation in women with preclinical rheumatoid arthritis
    Bing Lu
    Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Arthritis Rheum 62:3554-9. 2010
    ..To examine the association between alcohol consumption and markers of inflammation in preclinical rheumatoid arthritis (RA)...
  98. pmc An evaluation of the relationship between the implementation of a newly designed prescription drug label at Target pharmacies and health outcomes
    William H Shrank
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Med Care 47:1031-5. 2009
    ..A new prescription medication labeling system was implemented by Target pharmacies in May 2005 and aimed to improve health outcomes...
  99. ncbi request reprint Adherence with osteoporosis practice guidelines: a multilevel analysis of patient, physician, and practice setting characteristics
    Daniel H Solomon
    Division of Pharmacoepidemiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Am J Med 117:919-24. 2004
    ..The diagnosis and treatment of patients at risk of fragility fractures is uncommon. We examined the patient, physician, and practice characteristics associated with adherence to local osteoporosis guidelines...
  100. doi request reprint Nonselective and cyclooxygenase-2-selective NSAIDs and acute kidney injury
    Wolfgang C Winkelmayer
    The Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Am J Med 121:1092-8. 2008
    ..We undertook a large pharmacoepidemiologic analysis of the risk of acute kidney injury among older adults using nonselective NSAIDs or cyclooxygenase (COX)-2 inhibitors...
  101. doi request reprint Osteoporosis medication use in nursing home patients with fractures in 1 US state
    Seema Parikh
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Womens Hospital, Harvard Medical School, Boston, MA 02120, USA
    Arch Intern Med 168:1111-5. 2008
    ..We studied the patterns and predictors of osteoporosis medication use in elderly patients who sustained a fracture and were admitted to an NH...