- Donepezil: an update
V A Boston Healthcare System, Department of Neurology, Harvard Medical School, Geriatric Research Center, Boston, MA 02130, USA
Expert Opin Pharmacother 8:1011-23. 2007
..However, in general, the efficacy of donepezil is limited, and ongoing studies are investigating other agents that may ultimately overtake its present position as the mainstay of anti-AD therapy...
- Is long-term treatment of Alzheimer's disease with cholinesterase inhibitor therapy justified?
Department of Neurology, Harvard Medical School, Boston, Massachusetts, USA
Drugs Aging 24:881-90. 2007
..The most contentious issue regarding long-term treatment is economic, but the majority of available economic analyses suggest net savings over the long term if patients with AD receive persistent treatment with ChEIs...
- Posterior cingulate and retrosplenial cortex connections of the caudal superior temporal region in the rhesus monkey
VA Boston Healthcare System, Department of Neurology, Harvard Medical School, Boston, MA 02130, USA
Exp Brain Res 195:325-34. 2009
..It is suggested that this connectional pattern of the caudal STG is consistent with its putative role of localizing sounds in space as proposed in recent studies...
- Galantamine-ER for the treatment of mild-to-moderate Alzheimer's disease
Geriatric Research, Education and Clinical Center, V A Boston Healthcare System, Department of Neurology, Harvard Medical School, Boston, MA, USA
Clin Interv Aging 5:1-6. 2010
..Since its release onto the market galantamine-ER has enjoyed wide popularity and a recent surveillance study suggests that it has the highest 1-year persistence rate of all the ChEIs...
- Efficacy of donepezil in early-stage Alzheimer disease: a randomized placebo-controlled trial
Department of Psychiatry and Neurology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112 2699, USA
Arch Neurol 61:1852-6. 2004
..To evaluate the efficacy of donepezil in patients with early-stage Alzheimer disease...
- Donepezil: a review
Tulane University School of Medicine, Department of Psychiatry and Neurology, 1430 Tulane Avenue HC82, New Orleans, Louisiana 70112, USA
Expert Opin Drug Metab Toxicol 1:527-36. 2005
..Although donepezil was originally developed to inhibit the breakdown of the neurotransmitter acetylcholine as symptomatic therapy for AD, recent studies raise the possibility of other effects this drug has on the pathogenesis of AD...
- Cognitive components of deficit awareness in Alzheimer's disease
Lisa M Duke
Mental Health Service Line, Veterans Affairs Medical Center, New Orleans, Louisiana, USA
Neuropsychology 16:359-69. 2002
..AD patients may display intact immediate awareness of memory dysfunction but fail to incorporate incidents of memory failure into generalized self-belief systems...