Elisabetta Patorno

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. doi request reprint The Role of Hemoglobin Laboratory Test Results for the Detection of Upper Gastrointestinal Bleeding Outcomes Resulting from the Use of Medications in Observational Studies
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont Street Suite 3030, Boston, MA, 02120, USA
    Drug Saf 40:91-100. 2017
  2. doi request reprint Patterns of β-blocker initiation in patients undergoing intermediate to high-risk noncardiac surgery
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA Electronic address
    Am Heart J 170:812-820.e6. 2015
  3. doi request reprint Addressing limitations in observational studies of the association between glucose-lowering medications and all-cause mortality: a review
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street Suite 3030, Boston, MA, 02120, USA
    Drug Saf 38:295-310. 2015
  4. doi request reprint Observational studies of the association between glucose-lowering medications and cardiovascular outcomes: addressing methodological limitations
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont Street Suite 3030, Boston, MA, 02120, USA
    Diabetologia 57:2237-50. 2014
  5. pmc Comparative safety of anesthetic type for hip fracture surgery in adults: retrospective cohort study
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    BMJ 348:g4022. 2014
  6. doi request reprint Anticonvulsant medications and the risk of suicide, attempted suicide, or violent death
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, 1620 Tremont St, Ste 3030, Boston, MA 02120, USA
    JAMA 303:1401-9. 2010
  7. pmc Angiotensin-Converting Enzyme Inhibitors and the Risk of Congenital Malformations
    Brian T Bateman
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine and the Division of Endocrinology, Diabetes and Metabolism, Brigham and Women s Hospital, Harvard Medical School, The Department of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, and the Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts and the Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, New York
    Obstet Gynecol . 2016
  8. pmc Late Pregnancy β Blocker Exposure and Risks of Neonatal Hypoglycemia and Bradycardia
    Brian T Bateman
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, and Department of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts and
    Pediatrics 138:. 2016
  9. pmc Brief Report: Patterns and Secular Trends in Use of Immunomodulatory Agents During Pregnancy in Women With Rheumatic Conditions
    Rishi J Desai
    Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts
    Arthritis Rheumatol 68:1183-9. 2016
  10. pmc Initiation patterns of statin therapy among adult patients undergoing intermediate to high-risk non-cardiac surgery
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 25:64-72. 2016

Collaborators

Detail Information

Publications20

  1. doi request reprint The Role of Hemoglobin Laboratory Test Results for the Detection of Upper Gastrointestinal Bleeding Outcomes Resulting from the Use of Medications in Observational Studies
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont Street Suite 3030, Boston, MA, 02120, USA
    Drug Saf 40:91-100. 2017
    ..The use of hemoglobin laboratory results might increase the detection of UGI events that do not lead to hospitalization...
  2. doi request reprint Patterns of β-blocker initiation in patients undergoing intermediate to high-risk noncardiac surgery
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA Electronic address
    Am Heart J 170:812-820.e6. 2015
    ..In 2008, a large RCT (POISE trial) showed an increased mortality risk associated with perioperative β-blockade, raising concerns about an extensive β-Blocker use...
  3. doi request reprint Addressing limitations in observational studies of the association between glucose-lowering medications and all-cause mortality: a review
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street Suite 3030, Boston, MA, 02120, USA
    Drug Saf 38:295-310. 2015
    ..The implementation of suitable research methods can reduce the potential for spurious findings, and thus the risk of misleading the medical community about benefits and harms of diabetes therapy. ..
  4. doi request reprint Observational studies of the association between glucose-lowering medications and cardiovascular outcomes: addressing methodological limitations
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont Street Suite 3030, Boston, MA, 02120, USA
    Diabetologia 57:2237-50. 2014
    ..However, many of the studies are based on designs or analyses that inadequately address the methodological challenges involved...
  5. pmc Comparative safety of anesthetic type for hip fracture surgery in adults: retrospective cohort study
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    BMJ 348:g4022. 2014
    ..To evaluate the effect of anesthesia type on the risk of in-hospital mortality among adults undergoing hip fracture surgery in the United States...
  6. doi request reprint Anticonvulsant medications and the risk of suicide, attempted suicide, or violent death
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, 1620 Tremont St, Ste 3030, Boston, MA 02120, USA
    JAMA 303:1401-9. 2010
    ..The decision was based on a meta-analysis not sufficiently large to investigate individual drugs...
  7. pmc Angiotensin-Converting Enzyme Inhibitors and the Risk of Congenital Malformations
    Brian T Bateman
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine and the Division of Endocrinology, Diabetes and Metabolism, Brigham and Women s Hospital, Harvard Medical School, The Department of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, and the Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts and the Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, New York
    Obstet Gynecol . 2016
    ..To examine the association between first-trimester angiotensin-converting enzyme (ACE) inhibitor exposure and the risk of overall major congenital, cardiac, and central nervous system malformations...
  8. pmc Late Pregnancy β Blocker Exposure and Risks of Neonatal Hypoglycemia and Bradycardia
    Brian T Bateman
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, and Department of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts and
    Pediatrics 138:. 2016
    ..We sought to define the risks of neonatal hypoglycemia and bradycardia associated with maternal exposure to β blockers at the time of delivery in a large, nationwide cohort of Medicaid beneficiaries...
  9. pmc Brief Report: Patterns and Secular Trends in Use of Immunomodulatory Agents During Pregnancy in Women With Rheumatic Conditions
    Rishi J Desai
    Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts
    Arthritis Rheumatol 68:1183-9. 2016
    ..To describe patterns and secular trends in the use of immunomodulatory agents in pregnant women with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), psoriatic arthritis (PsA), or ankylosing spondylitis (AS)...
  10. pmc Initiation patterns of statin therapy among adult patients undergoing intermediate to high-risk non-cardiac surgery
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Pharmacoepidemiol Drug Saf 25:64-72. 2016
    ..However, evidence remains inconsistent, and little is known about the patterns of perioperative statin use in routine care...
  11. pmc Antipsychotic Use in Pregnancy and the Risk for Congenital Malformations
    Krista F Huybrechts
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts
    JAMA Psychiatry 73:938-46. 2016
    ..However, little is known about their safety for the developing fetus, and concerns have been raised about a potential association with congenital malformations...
  12. pmc Exposure to prescription opioid analgesics in utero and risk of neonatal abstinence syndrome: population based cohort study
    Rishi J Desai
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
    BMJ 350:h2102. 2015
    ....
  13. pmc Variations in the Use of Perioperative Multimodal Analgesic Therapy
    Karim S Ladha
    From the Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts K S L, E P, K F H, J L, B T B Department of Anesthesiology, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts K S L, B T B Department of Anesthesia, Toronto General Hospital and University of Toronto, Toronto, Ontario, Canada K S L and Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts J P R
    Anesthesiology 124:837-45. 2016
    ..However, the proportion of patients who actually receive this evidence-based approach is unknown. The objective of this study was to describe hospital-level patterns in the utilization of perioperative multimodal analgesia...
  14. pmc Antidepressant use late in pregnancy and risk of persistent pulmonary hypertension of the newborn
    Krista F Huybrechts
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts2Harvard Medical School, Boston, Massachusetts
    JAMA 313:2142-51. 2015
    ....
  15. doi request reprint Studies with many covariates and few outcomes: selecting covariates and implementing propensity-score-based confounding adjustments
    Elisabetta Patorno
    From the aDivision of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA and bDepartment of Epidemiology, Harvard School of Public Health, Boston, MA
    Epidemiology 25:268-78. 2014
    ..However, with few exposed outcomes to inform covariate selection and many candidate confounders, optimal approaches to construct and implement propensity-score-based confounding adjustment remain unclear...
  16. pmc Risk of ischemic cerebrovascular and coronary events in adult users of anticonvulsant medications in routine care settings
    Elisabetta Patorno
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA
    J Am Heart Assoc 2:e000208. 2013
    ....
  17. pmc Impact of Perioperative Epidural Placement on Postdischarge Opioid Use in Patients Undergoing Abdominal Surgery
    Karim S Ladha
    From the Department of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts K S L, B T B Department of Anesthesia, Toronto General Hospital and University of Toronto, Toronto, Ontario, Canada K S L and Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts E P, J L, B T B
    Anesthesiology 124:396-403. 2016
    ..Epidurals have been posited to prevent the development of persistent pain, but there are little data on the effect of epidurals on persistent opioid use...
  18. pmc Calcium Channel Blocker Exposure in Late Pregnancy and the Risk of Neonatal Seizures
    Brian T Bateman
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, and the Division of Endocrinology, Diabetes and Metabolism, Brigham and Women s Hospital and Harvard Medical School, the Departments of Anesthesiology, Critical Care, and Pain Medicine and Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, and the Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts
    Obstet Gynecol 126:271-8. 2015
    ..To assess whether maternal calcium channel blocker exposure during late pregnancy is independently associated with neonatal seizures after carefully controlling for confounding factors...
  19. doi request reprint Variable Selection for Confounding Adjustment in High-dimensional Covariate Spaces When Analyzing Healthcare Databases
    Sebastian Schneeweiss
    From the aDivision of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA and bAetion Inc, New York, NY
    Epidemiology 28:237-248. 2017
    ..Improvements seemed possible if outcome predictors were reliably identified empirically and adjusted...
  20. ncbi request reprint Limited Hospital Variation in the Use and Yield of CT for Pulmonary Embolism in Patients Undergoing Total Hip or Total Knee Replacement Surgery
    Kanako K Kumamaru
    From the Applied Imaging Science Laboratory, Department of Radiology K K K, F J R, Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine H K, B T B, J L, E P, and Department of Orthopedics L D H, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont St, Suite 3030, Boston, MA 02120 Department of Radiology, Juntendo University, Tokyo, Japan K K K, S A Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, Mass B T B Department of Biostatistics, Harvard University, Boston, Mass J G, T C and Department of Radiology, University of Tokyo, Tokyo, Japan K O
    Radiology 281:826-834. 2016
    ..Conclusion Limited interhospital variation in use and yield of in-hospital CT PA was observed among patients undergoing TKR or THR in the United States. © RSNA, 2016 Online supplemental material is available for this article...