Nancy J Keuthen
Affiliation: Massachusetts General Hospital
- Open-label escitalopram treatment for pathological skin pickingNancy J Keuthen
Massachusetts General Hospital Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA
Int Clin Psychopharmacol 22:268-74. 2007..These results suggest that escitalopram can be an effective agent in reducing pathological skin picking. The lack of medication response in a subset of our sample suggests the possibility of pathological skin picking subtypes...
- Predictors of comorbid obsessive-compulsive disorder and skin-picking disorder in trichotillomaniaNancy J Keuthen
Department of Psychiatry, Massachusetts General Hospital Harvard Medical School, Boston, MA USA E mail
Ann Clin Psychiatry 28:280-288. 2016..This study sought to identify factors that predict OCD and SPD in hair pullers...
- NEO-FFI personality clusters in trichotillomaniaNancy J Keuthen
Department of Psychiatry, Massachusetts General Hospital Harvard Medical School, Boston MA 02114, USA Electronic address
Psychiatry Res 239:196-203. 2016..Those in cluster 1 endorsed greater depression, anxiety, and stress, and worse quality of life. Additionally, only depression and cluster membership (based on NEO scores) significantly predicted quality of life...
- A comparison of clinical vs subclinical skin pickers in IsraelNancy J Keuthen
Massachusetts General Hospital Trichotillomania Clinic, Boston, MA, USA E mail
Ann Clin Psychiatry 28:98-104. 2016..Identifying differences between these 2 groups may improve diagnostic accuracy, treatment, and prevention efforts...
- Replication study of the milwaukee inventory for subtypes of trichotillomania-adult version in a clinically characterized sampleNancy J Keuthen
Massachusetts General Hospital, Boston, MA, USA
Behav Modif 39:580-99. 2015..Both scales displayed good construct and discriminant validity. These findings indicate the need for a revised scale that provides a more refined assessment of pulling phenomenology that can facilitate future treatment advances. ..
- The relationship between hair pulling style and quality of lifeEsther S Tung
Department of Psychiatry Massachusetts General Hospital Boston, MA USA E mail
Ann Clin Psychiatry 26:193-8. 2014..This study examined HP styles (automatic vs focused) for their associations with QOL and whether depression accounted for these relationships...
- Getting the word out: cognitive-behavioral therapy for trichotillomania (hair-pulling disorder) and excoriation (skin-picking) disorderNancy J Keuthen
Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA E mail
Ann Clin Psychiatry 27:10-5. 2015..To date, there has been no investigation of dissemination outcomes for cognitive-behavioral training programs for body-focused repetitive behaviors (BFRBs)...
- Evidence for reduced cerebellar volumes in trichotillomaniaNancy J Keuthen
Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
Biol Psychiatry 61:374-81. 2007..Limited knowledge exists regarding the neurobiology of trichotillomania (TTM). Cerebellum (CBM) volumes were explored, given its role in complex, coordinated motor sequences...
- The prevalence of pathologic skin picking in US adultsNancy J Keuthen
Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Compr Psychiatry 51:183-6. 2010..Despite increasing recognition of the potentially severe medical and psychosocial costs of pathologic skin picking (PSP), no large-sample, randomized investigation of its prevalence in a national population has been conducted...
- Pilot trial of dialectical behavior therapy-enhanced habit reversal for trichotillomaniaNancy J Keuthen
Massachusetts General Hospital Harvard Medical School, Boston, USA
Depress Anxiety 27:953-9. 2010..Not all hair pullers improve acutely with cognitive-behavioral treatment (CBT) and few maintain their gains over time...
- DBT-enhanced habit reversal treatment for trichotillomania: 3-and 6-month follow-up resultsNancy J Keuthen
Trichotillomania Clinic and Research Unit, Massachusetts General Hospital Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA
Depress Anxiety 28:310-3. 2011..Maintenance of gains with cognitive-behavioral treatment for trichotillomania (TTM) has historically been problematic...
- Factor analysis of the Massachusetts General Hospital Hairpulling ScaleNancy J Keuthen
Massachusetts General Hospital Harvard Medical School, Boston, MA 02114, USA
J Psychosom Res 62:707-9. 2007..We explored the factor structure of the Massachusetts General Hospital Hairpulling Scale (MGH-HPS), a self-report measure for trichotillomania (TTM)...
- Severe obsessive-compulsive disorder with and without comorbid hair pulling: comparisons and clinical implicationsS Evelyn Stewart
McLean Hospital, Boston, Mass, USA
J Clin Psychiatry 66:864-9. 2005..This study determined the prevalence of hair pulling in an inpatient obsessive-compulsive disorder (OCD) population and compared clinical characteristics and treatment response between subgroups with and without comorbid hair pulling...
- Open-label study of high (30 mg) and moderate (20 mg) dose escitalopram for the treatment of obsessive-compulsive disorderDarin D Dougherty
Department of Psychiatry, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA
Int Clin Psychopharmacol 24:306-11. 2009..These results suggest that the 30 mg (vs. 20 mg) dose of escitalopram may provide a superior reduction in OCD symptoms for those sufferers with comorbid depression and/or anxiety...
- Motor inhibition in trichotillomania and obsessive-compulsive disorderAntje Bohne
Massachusetts General Hospital Harvard Medical School, OCD Clinic, Simches Research Building, 2nd Floor, 185 Cambridge Street, Boston, MA 02114, USA
J Psychiatr Res 42:141-50. 2008..There was no evidence for motor inhibition deficits in OCD. Based on our data, a subgroup of TTM sufferers seems to be characterized by motor inhibition deficits...
- Visuospatial abilities, memory, and executive functioning in trichotillomania and obsessive-compulsive disorderAntje Bohne
Massachusetts General Hospital Harvard Medical School, OCD Clinic, Charlestown, MA 02129, USA
J Clin Exp Neuropsychol 27:385-99. 2005..Other executive functions, as well as memory and visuospatial abilities were unimpaired in TTM and OCD. Our data suggest that TTM and OCD are characterized by different patterns of neuropsychological dysfunction...
- Single modality versus dual modality treatment for trichotillomania: sertraline, behavioral therapy, or both?Darin D Dougherty
Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
J Clin Psychiatry 67:1086-92. 2006..However, no randomized, controlled studies to date have compared the efficacy of individual SSRI or CBT treatment to the combination of both treatment modalities...
- Prevalence of symptoms of body dysmorphic disorder and its correlates: a cross-cultural comparisonAntje Bohne
Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA
Psychosomatics 43:486-90. 2002..Body image concerns and preoccupation were significantly greater in American than in German students, although the prevalence of probable body dysmorphic disorder was not...
- Cognitive-behavior therapy for self-injurious skin picking. A case seriesThilo Deckersbach
Harvard Medical School, Cognitive Behavior Therapy Program, Obsessive Compulsive Disorder Clinic, Psychiatric Neuroscience Program, Massachusetts General Hospital, USA
Behav Modif 26:361-77. 2002..In the current article, the authors describe the implementation and outcome of cognitive-behavior therapy for three patients with severe self-injurious skin picking, two of which had psychiatric comorbidity...
- Brain activation during implicit sequence learning in individuals with trichotillomaniaScott L Rauch
Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Psychiatry Res 154:233-40. 2007..Future studies directly comparing OCD and TTM subjects are warranted to confirm the specificity of abnormal striatal and hippocampal findings during implicit sequence learning in OCD...
- Cognitive inhibition in trichotillomania and obsessive-compulsive disorderAntje Bohne
Massachusetts General Hospital, Harvard Medical School, OCD Clinic, 9th Floor, 149 Thirteenth Street, Charlestown, MA 02129, USA
Behav Res Ther 43:923-42. 2005..In conclusion, although attention was disproportionately directed towards negative information in both disorders, cognitive inhibition deficits appeared specific to OCD...
- Trichotillomania and personality traits from the five-factor modelNancy J Keuthen
Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
Rev Bras Psiquiatr 37:317-24. 2015..To examine whether personality traits have predictive validity for trichotillomania (TTM) diagnosis, pulling severity and control, and hair pulling style...
- Brain correlates of negative and positive visuospatial priming in adultsChristopher I Wright
Psychiatric Neuroimaging Research Program and Martinos Imaging Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
Neuroimage 30:983-91. 2006..In conjunction with functional MRI, this visuospatial priming task may be useful for studying the pathophysiology of neuropsychiatric disorders in which deficient inhibitory processing or excessive facilitation is a feature...
- Skin picking in German students. Prevalence, phenomenology, and associated characteristicsAntje Bohne
Massachusetts General Hospital, Harvard Medical School, USA
Behav Modif 26:320-39. 2002..6%). About 20% (n = 26) ate the picked tissue afterward. Results suggest SP is an underrecognized problem that occurs on a continuum ranging from mild to severe with generally stable clinical characteristics across cultures...
- Prevalence of irritable bowel syndrome in obsessive-compulsive disorderPrakash S Masand
Department of Psychiatry, Duke University Medical Center, Durham, NC 27705, USA
CNS Spectr 11:21-5. 2006..Irritable bowel syndrome (IBS) occurs more frequently in psychiatric patients, especially those with anxiety and mood disorders...
- Open-label study of duloxetine for the treatment of obsessive-compulsive disorderDarin D Dougherty
Division of Neurotherapeutics, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA Drs Dougherty, Corse, CHOU, DUFFY, Arulpragasam, and Deckersbach OCD and Related Disorders Program, Massachusetts General Hospital, Boston, MA Drs Dougherty, Jenike, and Keuthen Department of Psychology, Harvard University, Cambridge, MA Dr Chou Department of Neuroscience, Brown University, Providence, RI Dr Duffy
Int J Neuropsychopharmacol 18:. 2015..This study sought to investigate the efficacy of duloxetine for the treatment of obsessive-compulsive disorder (DSM-IV)...
- Predictors of life disability in trichotillomaniaEsther S Tung
Department of Psychiatry, Massachusetts General Hospital, 185 Cambridge St, Suite 2200, Boston, MA, 02114, USA Electronic address
Compr Psychiatry 56:239-44. 2015..Disability was measured in individual life areas (work, social, and family/home life) instead of as a total disability score as in previous studies...
- A family study of trichotillomania and chronic hair pullingNancy J Keuthen
Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts
Am J Med Genet B Neuropsychiatr Genet 165:167-74. 2014..The data did not provide evidence for an etiologic relationship between HP and SP. Replication of these findings in future studies with larger cohorts of case and control relatives is warranted...
- StopPicking.com: Internet-based treatment for self-injurious skin pickingChristopher A Flessner
University of Wisconsin Milwaukee, USA
Dermatol Online J 13:3. 2007..com may provide an alternative or adjunctive treatment for SP. The current study is limited by lack of a control condition and use of a non-referred sample of skin pickers...
- The Milwaukee Inventory for Styles of Trichotillomania-Child Version (MIST-C): initial development and psychometric propertiesChristopher A Flessner
University of Wisconsin Milwaukee, USA
Behav Modif 31:896-918. 2007....
- Trichotillomania, stereotypic movement disorder, and related disordersDan J Stein
UCT Department of Psychiatry, Groote Schuur Hospital J 2, Observatory 7925, Cape Town, South Africa
Curr Psychiatry Rep 9:301-2. 2007..Such disorders deserve greater recognition in the official nosology, and there would seem to be clinical utility in classifying them in the same diagnostic category...
- Current posttraumatic stress disorder and history of trauma in trichotillomaniaBeth S Gershuny
Department of Psychology, Skidmore College, 815 N Broadway, Saratoga Springs, NY 12866, USA
J Clin Psychol 62:1521-9. 2006..The authors also speculate that in traumatized individuals, TTM may represent a form of coping vis-à-vis self-soothing or self-harm...
- Influence of fluoxetine on positive and negative affect in a clinic-based smoking cessation trialJessica Werth Cook
Department of Psychology, 1007 West Harrison Avenue, Chicago, IL 60607 7137, USA
Psychopharmacology (Berl) 173:153-9. 2004..Fluoxetine improves affect in clinical syndromes such as depression and premenstrual dysphoric disorder. Little is known about fluoxetine's influence on mood changes after quitting smoking, which often resemble sub-clinical depression...
- Styles of pulling in trichotillomania: exploring differences in symptom severity, phenomenology, and functional impactChristopher A Flessner
Department of Psychology, University of Wisconsin Milwaukee, Milwaukee, Milwaukee, WI 53211, USA
Behav Res Ther 46:345-57. 2008..Clinical and research implications, study limitations, and future areas of research are discussed...
- The trichotillomania scale for children: development and validationDavid F Tolin
The Institute of Living, Anxiety Disorders Center, 200 Retreat Avenue, Hartford, CT 06106, USA
Child Psychiatry Hum Dev 39:331-49. 2008..The present results suggest that the TSC may be a useful measure of TTM for child and adolescent samples, although additional clarification of convergent validity is needed...
- The Trichotillomania Impact Project (TIP): exploring phenomenology, functional impairment, and treatment utilizationDouglas W Woods
Department of Psychology, University of Wisconsin Milwaukee, 53211, USA
J Clin Psychiatry 67:1877-88. 2006..The current study (i.e., The Trichotillomania Impact Project) was designed to provide initial information regarding these issues...
- Prevalence of body dysmorphic disorder in a German college student sampleAntje Bohne
Massachusetts General Hospital East Harvard Medical School, OCD Clinic, 149 Thirteenth Street, Charlestown, MA 02129, USA
Psychiatry Res 109:101-4. 2002..One student with BDD also reported severe skin picking. In conclusion, BDD is a common psychiatric disorder in college students...