Assunta De Rienzo

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma
    Assunta De Rienzo
    The Thoracic Surgery Oncology laboratory and the International Mesothelioma Program, Division of Thoracic Surgery and the Lung Center, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts
    Cancer Res 76:319-28. 2016
  2. pmc Sequential binary gene ratio tests define a novel molecular diagnostic strategy for malignant pleural mesothelioma
    Assunta De Rienzo
    The Thoracic Surgery Oncology Laboratory, and International Mesothelioma Program, Division of Thoracic Surgery, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts 02115, USA
    Clin Cancer Res 19:2493-502. 2013
  3. pmc Fine-needle aspiration biopsies for gene expression ratio-based diagnostic and prognostic tests in malignant pleural mesothelioma
    Assunta De Rienzo
    The Thoracic Surgery Oncology Laboratory and International Mesothelioma Program, and Division of Thoracic Surgery, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
    Clin Cancer Res 17:310-6. 2011
  4. pmc Second generation sequencing of the mesothelioma tumor genome
    Raphael Bueno
    The International Mesothelioma Program, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 5:e10612. 2010
  5. pmc Gene expression ratio test distinguishes normal lung from lung tumors in solid tissue and FNA biopsies
    Assunta De Rienzo
    Thoracic Surgery Oncology Laboratory and the International Mesothelioma Program, Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, Massachusetts Department of Surgery, Harvard Medical School, Boston, Massachusetts
    J Mol Diagn 16:267-72. 2014
  6. doi request reprint Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations
    Raphael Bueno
    Division of Thoracic Surgery, The Lung Center and the International Mesothelioma Program, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Nat Genet 48:407-16. 2016
  7. pmc Differentially expressed alternatively spliced genes in malignant pleural mesothelioma identified using massively parallel transcriptome sequencing
    Lingsheng Dong
    The Thoracic Surgery Oncology Laboratory and Division of Thoracic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    BMC Med Genet 10:149. 2009

Detail Information

Publications7

  1. pmc Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma
    Assunta De Rienzo
    The Thoracic Surgery Oncology laboratory and the International Mesothelioma Program, Division of Thoracic Surgery and the Lung Center, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts
    Cancer Res 76:319-28. 2016
    ..Collectively, our findings indicate that diverse mechanisms highly related to gender and histology appear to drive MPM...
  2. pmc Sequential binary gene ratio tests define a novel molecular diagnostic strategy for malignant pleural mesothelioma
    Assunta De Rienzo
    The Thoracic Surgery Oncology Laboratory, and International Mesothelioma Program, Division of Thoracic Surgery, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts 02115, USA
    Clin Cancer Res 19:2493-502. 2013
    ..In addition, we searched for pathways relevant in MPM in comparison with other related cancers to identify unique molecular features in MPM...
  3. pmc Fine-needle aspiration biopsies for gene expression ratio-based diagnostic and prognostic tests in malignant pleural mesothelioma
    Assunta De Rienzo
    The Thoracic Surgery Oncology Laboratory and International Mesothelioma Program, and Division of Thoracic Surgery, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
    Clin Cancer Res 17:310-6. 2011
    ..We postulated that the accuracy of FNA-based diagnosis might be improved by the addition of molecular tests using a gene expression ratio-based algorithm and that prognostic tests could be similarly performed...
  4. pmc Second generation sequencing of the mesothelioma tumor genome
    Raphael Bueno
    The International Mesothelioma Program, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 5:e10612. 2010
    ..Second-generation sequencing uncovered all types of mutations in this MPM tumor, with DNA rearrangements representing the dominant type...
  5. pmc Gene expression ratio test distinguishes normal lung from lung tumors in solid tissue and FNA biopsies
    Assunta De Rienzo
    Thoracic Surgery Oncology Laboratory and the International Mesothelioma Program, Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, Massachusetts Department of Surgery, Harvard Medical School, Boston, Massachusetts
    J Mol Diagn 16:267-72. 2014
    ..This study supports the hypothesis that the gene-ratio approach reliably distinguishes normal lung from cancerous tissues in FNA samples and can be optimized to diagnose benign nodules. ..
  6. doi request reprint Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations
    Raphael Bueno
    Division of Thoracic Surgery, The Lung Center and the International Mesothelioma Program, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Nat Genet 48:407-16. 2016
    ..Through integrated analyses, we identified alterations in Hippo, mTOR, histone methylation, RNA helicase and p53 signaling pathways in MPMs. ..
  7. pmc Differentially expressed alternatively spliced genes in malignant pleural mesothelioma identified using massively parallel transcriptome sequencing
    Lingsheng Dong
    The Thoracic Surgery Oncology Laboratory and Division of Thoracic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    BMC Med Genet 10:149. 2009
    ..We hypothesized that alternative splicing profiles might be detected in the sequencing data for the expressed genes in these samples...