Cristina Cusin

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. doi request reprint Rapid improvement of depression and psychotic symptoms in Huntington's disease: a retrospective chart review of seven patients treated with electroconvulsive therapy
    Cristina Cusin
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA Electronic address
    Gen Hosp Psychiatry 35:678.e3-5. 2013
  2. doi request reprint A randomized, double-blind, placebo-controlled trial of pramipexole augmentation in treatment-resistant major depressive disorder
    Cristina Cusin
    Depression Clinical and Research Program, Massachusetts General Hospital, One Bowdoin Square, Ste 630, Boston, MA 02114, USA
    J Clin Psychiatry 74:e636-41. 2013
  3. pmc Somatic therapies for treatment-resistant depression: ECT, TMS, VNS, DBS
    Cristina Cusin
    Division of Neurotherapeutics, Department of Psychiatry, Massachusetts General Hospital, 149 13th Street, Rm 2612, Charlestown, MA 02129, USA
    Biol Mood Anxiety Disord 2:14. 2012
  4. ncbi request reprint Early symptomatic worsening during treatment with fluoxetine in major depressive disorder: prevalence and implications
    Cristina Cusin
    Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychiatry 68:52-7. 2007
  5. ncbi request reprint Treatment-associated suicidal ideation and adverse effects in an open, multicenter trial of fluoxetine for major depressive episodes
    Roy H Perlis
    Depression Clinical and Research Program, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Psychother Psychosom 76:40-6. 2007
  6. doi request reprint Treatment Outcome in Depressed Latinos Predicted by Concomitant Psychosislike Symptoms
    Paolo Cassano
    Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston and North Suffolk Mental Health Association, Chelsea, MA
    J Nerv Ment Dis 203:769-73. 2015
  7. doi request reprint Efficacy and safety of a form of cranial electrical stimulation (CES) as an add-on intervention for treatment-resistant major depressive disorder: A three week double blind pilot study
    David Mischoulon
    Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA Electronic address
    J Psychiatr Res 70:98-105. 2015
  8. ncbi request reprint Antidepressant response and well-being in pre-, peri- and postmenopausal women with major depressive disorder treated with fluoxetine
    Paolo Cassano
    The Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA 02114, USA
    Psychother Psychosom 74:362-5. 2005
  9. ncbi request reprint Clinical and genetic dissection of anger expression and CREB1 polymorphisms in major depressive disorder
    Roy H Perlis
    Depression Clinical and Research Program, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Biol Psychiatry 62:536-40. 2007
  10. pmc Association between physician beliefs regarding assigned treatment and clinical response: re-analysis of data from the Hypericum Depression Trial Study Group
    Justin A Chen
    Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Asian J Psychiatr 13:23-9. 2015

Detail Information

Publications21

  1. doi request reprint Rapid improvement of depression and psychotic symptoms in Huntington's disease: a retrospective chart review of seven patients treated with electroconvulsive therapy
    Cristina Cusin
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA Electronic address
    Gen Hosp Psychiatry 35:678.e3-5. 2013
    ..Our case series supports the hypothesis of a positive risk-benefit ratio for ECT in patients with HD and severe depression or psychosis. ..
  2. doi request reprint A randomized, double-blind, placebo-controlled trial of pramipexole augmentation in treatment-resistant major depressive disorder
    Cristina Cusin
    Depression Clinical and Research Program, Massachusetts General Hospital, One Bowdoin Square, Ste 630, Boston, MA 02114, USA
    J Clin Psychiatry 74:e636-41. 2013
    ..Existing augmentation or combination strategies can have substantial safety concerns that may limit their application...
  3. pmc Somatic therapies for treatment-resistant depression: ECT, TMS, VNS, DBS
    Cristina Cusin
    Division of Neurotherapeutics, Department of Psychiatry, Massachusetts General Hospital, 149 13th Street, Rm 2612, Charlestown, MA 02129, USA
    Biol Mood Anxiety Disord 2:14. 2012
    ..VNS has been FDA-approved for TRD, however it is not indicated for management of acute illness. DBS for TRD is still an experimental area of investigation and double-blind clinical trials are underway...
  4. ncbi request reprint Early symptomatic worsening during treatment with fluoxetine in major depressive disorder: prevalence and implications
    Cristina Cusin
    Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychiatry 68:52-7. 2007
    ..While patterns of response have been examined as possible predictors of outcome, the clinical correlates and implications of early worsening per se have not been investigated...
  5. ncbi request reprint Treatment-associated suicidal ideation and adverse effects in an open, multicenter trial of fluoxetine for major depressive episodes
    Roy H Perlis
    Depression Clinical and Research Program, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Psychother Psychosom 76:40-6. 2007
    ..The time course and clinical correlates of this phenomenon have not been characterized in detail...
  6. doi request reprint Treatment Outcome in Depressed Latinos Predicted by Concomitant Psychosislike Symptoms
    Paolo Cassano
    Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston and North Suffolk Mental Health Association, Chelsea, MA
    J Nerv Ment Dis 203:769-73. 2015
    ..The authors propose a phenomenological differentiation between benign psychosislike symptoms (clusters A-C) and the expression of the psychotic continuum (cluster D) in depressed Latinos. ..
  7. doi request reprint Efficacy and safety of a form of cranial electrical stimulation (CES) as an add-on intervention for treatment-resistant major depressive disorder: A three week double blind pilot study
    David Mischoulon
    Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA Electronic address
    J Psychiatr Res 70:98-105. 2015
    ..Since this form of CES has other settings, future studies should test these settings and compare it against other CES devices. Clinicaltrials.gov ID: NCT01325532. ..
  8. ncbi request reprint Antidepressant response and well-being in pre-, peri- and postmenopausal women with major depressive disorder treated with fluoxetine
    Paolo Cassano
    The Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA 02114, USA
    Psychother Psychosom 74:362-5. 2005
    ..We assessed the impact of menopausal status on treatment response and well-being in a cohort of outpatient women with major depressive disorder (DSM-III-R criteria), who received treatment with fluoxetine (20 mg/day for 8 weeks)...
  9. ncbi request reprint Clinical and genetic dissection of anger expression and CREB1 polymorphisms in major depressive disorder
    Roy H Perlis
    Depression Clinical and Research Program, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Biol Psychiatry 62:536-40. 2007
    ..Therefore, we examined the association between CREB1 polymorphisms and anger expression in MDD...
  10. pmc Association between physician beliefs regarding assigned treatment and clinical response: re-analysis of data from the Hypericum Depression Trial Study Group
    Justin A Chen
    Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Asian J Psychiatr 13:23-9. 2015
    ..We re-examined these data to determine whether clinical improvement was associated with physician belief about assigned therapy...
  11. ncbi request reprint Is there a placebo problem in antidepressant trials?
    Huaiyu Yang
    Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Curr Top Med Chem 5:1077-86. 2005
    ..These observations have led us to develop a novel approach to the placebo response problem called the Sequential Parallel Comparison Design...
  12. pmc Correlates of irritability in college students with depressive symptoms
    Paola Pedrelli
    Depression Clinical and Research Program, Massachusetts General Hospital, Boston and Wentworth Institute of Technology, Boston, MA
    J Nerv Ment Dis 201:953-8. 2013
    ..The findings from this study suggest that depressive symptoms and irritability may characterize a subtype of college students who have a greater symptom burden and with the potential need for more aggressive and prompt treatment. ..
  13. ncbi request reprint Clinical and demographic features of mood disorder subtypes
    Alessandro Serretti
    Department of Psychiatry, Vita Salute University, San Raffaele Institute, Via Luigi Prinetti 29, Milan, Italy
    Psychiatry Res 112:195-210. 2002
    ..This finding may help in the search for the biological basis of mood disorders...
  14. ncbi request reprint Influence of monoamine oxidase A and serotonin receptor 2A polymorphisms in SSRI antidepressant activity
    Cristina Cusin
    Department of Psychiatry, Vita Salute University, Raffaele del Monte Tabor, Milan, Italy
    Int J Neuropsychopharmacol 5:27-35. 2002
    ..The investigated MAOA and 5-HT-2A gene variants, therefore, do not seem to play a major role in SSRI antidepressant activity...
  15. ncbi request reprint Pooling pharmacogenetic studies on the serotonin transporter: a mega-analysis
    Alessandro Serretti
    Department of Psychiatry, Vita Salute University, Fondazione Centro San Raffaele del Monte Tabor, Milan, Italy
    Psychiatry Res 145:61-5. 2006
    ..This result supports the involvement of the SERTPR gene in response to antidepressant treatments...
  16. ncbi request reprint SSRIs antidepressant activity is influenced by G beta 3 variants
    Alessandro Serretti
    Department of Psychiatry, Vita Salute University, Fondazione Centro San Raffaele del Monte Tabor, Milan, Italy
    Eur Neuropsychopharmacol 13:117-22. 2003
    ..009) and this effect was independent from analyzed demographic and clinical variables. These results confirm preliminary reports and shed further light on the genetics of the response to antidepressant treatments...
  17. ncbi request reprint Further evidence of a combined effect of SERTPR and TPH on SSRIs response in mood disorders
    Alessandro Serretti
    Department of Psychiatry, Vita Salute University, San Raffaele Institute, Milan, Italy
    Am J Med Genet B Neuropsychiatr Genet 129:36-40. 2004
    ..Thus, the previous positive association was not fully replicated for TPH. The present independent replication confirms SERTPR variants as a liability factor for antidepressant efficacy while the TPH effect is not unequivocal...
  18. ncbi request reprint Insomnia improvement during antidepressant treatment and CLOCK gene polymorphism
    Alessandro Serretti
    Department of Neuropsychiatric Sciences, Istituto Scientifico, Universitario Ospedale San Raffaele, University of Milan School of Medicine, Via Luigi Prinetti 29, 20127 Milan, Italy
    Am J Med Genet B Neuropsychiatr Genet 137:36-9. 2005
    ..This, together with previous findings on this polymorphism could lead to a further dissection of the complexity of mood disorders...
  19. ncbi request reprint Seasonal variations of lithium plasma levels
    Cristina Cusin
    Department of Psychiatry, Vita Salute University, Fondazione Centro San Raffaele del Monte Tabor, Via Stamira d Ancona 20, 20127, Milan, Italy
    Psychiatry Res 111:35-41. 2002
    ..In conclusion, we observed a significant variation of lithium plasma levels according to seasons. If confirmed, this finding could have both clinical and research implications...
  20. ncbi request reprint Comparison of response to fluvoxamine in nondemented elderly compared to younger patients affected by major depression
    Raffaella Zanardi
    Department of Psychiatry San Raffaele Institute, Vita Salute University, Via Stamira d Ancona 20, 20127 Milan, Italy
    J Clin Psychopharmacol 23:535-9. 2003
    ..0006). This difference between the 2 age groups was evident since the 2nd week of treatment, and it appeared to be independent of other clinical variables...