William A Copen

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi Neurological disorders in pregnancy from a neuroimaging perspective
    Steven D Brass
    Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Semin Neurol 27:411-24. 2007
  2. doi Brain perfusion: computed tomography and magnetic resonance techniques
    William A Copen
    Division of Neuroradiology, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA Electronic address
    Handb Clin Neurol 135:117-35. 2016
  3. doi Multimodal imaging in acute ischemic stroke
    William A Copen
    Massachusetts General Hospital, Division of Neuroradiology, GRB 273A, 55 Fruit Street, Boston, MA, 02114, USA
    Curr Treat Options Cardiovasc Med 17:368. 2015
  4. doi Exposing hidden truncation-related errors in acute stroke perfusion imaging
    W A Copen
    From the Departments of Radiology W A C, A R D, P W S, R G G, O W
    AJNR Am J Neuroradiol 36:638-45. 2015
  5. doi Existence of the diffusion-perfusion mismatch within 24 hours after onset of acute stroke: dependence on proximal arterial occlusion
    William A Copen
    Department of Radiology, Massachusetts General Hospital, GRB 273A, 55 Fruit St, Boston, MA 02114, USA
    Radiology 250:878-86. 2009
  6. pmc MR perfusion imaging in acute ischemic stroke
    William A Copen
    Department of Radiology, Division of Neuroradiology, Massachusetts General Hospital, GRB 273A, 55 Fruit Street, Boston, MA 02114, USA
    Neuroimaging Clin N Am 21:259-83, x. 2011
  7. doi Combining acute diffusion-weighted imaging and mean transmit time lesion volumes with National Institutes of Health Stroke Scale Score improves the prediction of acute stroke outcome
    Albert J Yoo
    Department of Radiology, Massachusetts General Hospital, Boston, Mass 02114, USA
    Stroke 41:1728-35. 2010
  8. pmc Longitudinal Diffusion Tensor Imaging Detects Recovery of Fractional Anisotropy Within Traumatic Axonal Injury Lesions
    Brian L Edlow
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, 175 Cambridge Street Suite 300, Boston, MA, 02114, USA
    Neurocrit Care 24:342-52. 2016
  9. pmc In Acute Stroke, Can CT Perfusion-Derived Cerebral Blood Volume Maps Substitute for Diffusion-Weighted Imaging in Identifying the Ischemic Core?
    William A Copen
    Department of Radiology, Division of Neuroradiology, Massachusetts General Hospital, Boston, Massachusetts, United States of America Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 10:e0133566. 2015
  10. pmc Reliability of cerebral blood volume maps as a substitute for diffusion-weighted imaging in acute ischemic stroke
    Amy R Deipolyi
    Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Magn Reson Imaging 36:1083-7. 2012

Collaborators

Detail Information

Publications20

  1. ncbi Neurological disorders in pregnancy from a neuroimaging perspective
    Steven D Brass
    Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Semin Neurol 27:411-24. 2007
    ....
  2. doi Brain perfusion: computed tomography and magnetic resonance techniques
    William A Copen
    Division of Neuroradiology, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA Electronic address
    Handb Clin Neurol 135:117-35. 2016
    ....
  3. doi Multimodal imaging in acute ischemic stroke
    William A Copen
    Massachusetts General Hospital, Division of Neuroradiology, GRB 273A, 55 Fruit Street, Boston, MA, 02114, USA
    Curr Treat Options Cardiovasc Med 17:368. 2015
    ....
  4. doi Exposing hidden truncation-related errors in acute stroke perfusion imaging
    W A Copen
    From the Departments of Radiology W A C, A R D, P W S, R G G, O W
    AJNR Am J Neuroradiol 36:638-45. 2015
    ..We tested the potential magnitude of hidden errors related to the truncation of data by short perfusion scans...
  5. doi Existence of the diffusion-perfusion mismatch within 24 hours after onset of acute stroke: dependence on proximal arterial occlusion
    William A Copen
    Department of Radiology, Massachusetts General Hospital, GRB 273A, 55 Fruit St, Boston, MA 02114, USA
    Radiology 250:878-86. 2009
    ....
  6. pmc MR perfusion imaging in acute ischemic stroke
    William A Copen
    Department of Radiology, Division of Neuroradiology, Massachusetts General Hospital, GRB 273A, 55 Fruit Street, Boston, MA 02114, USA
    Neuroimaging Clin N Am 21:259-83, x. 2011
    ..This review discusses the basic pathophysiology of acute stroke, the utility of different kinds of perfusion images, and research on the continually evolving role of MR perfusion imaging in acute stroke care...
  7. doi Combining acute diffusion-weighted imaging and mean transmit time lesion volumes with National Institutes of Health Stroke Scale Score improves the prediction of acute stroke outcome
    Albert J Yoo
    Department of Radiology, Massachusetts General Hospital, Boston, Mass 02114, USA
    Stroke 41:1728-35. 2010
    ....
  8. pmc Longitudinal Diffusion Tensor Imaging Detects Recovery of Fractional Anisotropy Within Traumatic Axonal Injury Lesions
    Brian L Edlow
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, 175 Cambridge Street Suite 300, Boston, MA, 02114, USA
    Neurocrit Care 24:342-52. 2016
    ..We hypothesized that recovery of FA within a TAI lesion correlates with better functional outcome...
  9. pmc In Acute Stroke, Can CT Perfusion-Derived Cerebral Blood Volume Maps Substitute for Diffusion-Weighted Imaging in Identifying the Ischemic Core?
    William A Copen
    Department of Radiology, Division of Neuroradiology, Massachusetts General Hospital, Boston, Massachusetts, United States of America Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 10:e0133566. 2015
    ..We sought to determine whether DWI and CTP-derived CBV maps are equivalent in measuring core volume...
  10. pmc Reliability of cerebral blood volume maps as a substitute for diffusion-weighted imaging in acute ischemic stroke
    Amy R Deipolyi
    Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Magn Reson Imaging 36:1083-7. 2012
    ..Some propose using perfusion imaging, specifically CBV maps, in place of DWI. We examined whether CBV maps can reliably subsitute for DWI, and assessed the effect of scan duration on calculated CBV...
  11. ncbi Magnetic resonance perfusion-weighted imaging of acute cerebral infarction: effect of the calculation methods and underlying vasculopathy
    Kei Yamada
    Massachusetts General Hospital NMR Center, Harvard Medical School, Boston, USA
    Stroke 33:87-94. 2002
    ..Steno-occlusive disease in the parent vessels is another factor that may affect the results of the PWI. The purpose of this study was to elucidate the effect of the calculation methods and underlying vasculopathy on PWI...
  12. pmc The Massachusetts General Hospital acute stroke imaging algorithm: an experience and evidence based approach
    RAMON GILBERTO GONZALEZ
    Neuroradiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Neurointerv Surg 5:i7-12. 2013
    ....
  13. doi Time and diffusion lesion size in major anterior circulation ischemic strokes
    Reza Hakimelahi
    From the Neuroradiology Division and the Stroke Service, Massachusetts General Hospital, Harvard Medical School, Boston
    Stroke 45:2936-41. 2014
    ....
  14. pmc Optimal brain MRI protocol for new neurological complaint
    William A Mehan
    Neuroradiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 9:e110803. 2014
    ..It has not been documented which sequences are essential. We assessed the diagnostic accuracy of a limited number of sequences in patients with new neurologic complaints...
  15. doi Outcome in patients with H1N1 influenza and cerebrovascular injury treated with extracorporeal membrane oxygenation
    Felicia C Chow
    Department of Neurology, Massachusetts General Hospital, 15 Parkman Street, Wang Ambulatory Care Center, Suite 835, Boston, MA 02114, USA
    Neurocrit Care 15:156-60. 2011
    ..Although intracranial hemorrhage and infarction have been reported in patients with H1N1 influenza infection treated with extracorporeal membrane oxygenation (ECMO), the clinical outcomes of these patients are not well described...
  16. doi Improving door-to-needle times: a single center validation of the target stroke hypothesis
    Ilana M Ruff
    From the Departments of Neurology I R, S A, N R, L S, Radiology W C, M L, and Emergency Medicine J G, J M, Massachusetts General Hospital, Harvard Medical School, Boston, MA
    Stroke 45:504-8. 2014
    ..In 2007, we implemented a new institutional acute stroke care model to include 10 best practices and evaluated the effect of this intervention on improving door-to-computed tomography (CT) and door-to-needle (DTN) times at our hospital...
  17. pmc Role of Acute Lesion Topography in Initial Ischemic Stroke Severity and Long-Term Functional Outcomes
    Ona Wu
    From the Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital MGH, Charlestown, MA O W, S J T M, M J R J B JP Kistler Stroke Research Center, Department of Neurology L C, P T C P, K F, A K, J R, K L F, N S R, Division of Neuroradiology, Department of Radiology W A C, P W S, Division of Neurocritical Care and Emergency Neurology J R, and Center for Human Genetic Research J R, MGH, Boston, MA and Department of Neurology, Brown University, Providence, RI K L F
    Stroke 46:2438-44. 2015
    ..We hypothesized that the topography of acute stroke lesions on diffusion-weighted magnetic resonance imaging may provide further information with regard to presenting stroke severity and long-term functional outcomes...
  18. doi Time-resolved contrast-enhanced magnetic resonance angiography in the investigation of suspected intracranial dural arteriovenous fistula
    Benjamin D Schanker
    Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston Massachusetts 02114, USA
    J Clin Neurosci 18:837-9. 2011
    ..There was no evidence of arteriovenous shunting. Retrograde venous flow explained the signal abnormality seen on time-of-flight MRA. We concluded that time-resolved MRA is useful in the investigation of suspected intracranial dAVF...
  19. pmc Diffusion tensor imaging in acute-to-subacute traumatic brain injury: a longitudinal analysis
    Brian L Edlow
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    BMC Neurol 16:2. 2016
    ....
  20. pmc Early experience of translating pH-weighted MRI to image human subjects at 3 Tesla
    Phillip Zhe Sun
    Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, Mass 02129, USA
    Stroke 41:S147-51. 2010
    ..Tissue pH, a well-regulated physiological index that alters on disrupted tissue metabolism, may provide a surrogate metabolic imaging marker that augments the DWI and PWI for penumbra imaging...