Paul Conlin

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Dietary modification and changes in blood pressure
    P R Conlin
    Endocrinology Hypertension Division, Brigham and Women s Hospital, Medical Service, VA Boston Healthcare Syste, Boston, Massachusetts 02115, USA
    Curr Opin Nephrol Hypertens 10:359-63. 2001
  2. ncbi request reprint Redefining efficacy of antihypertensive therapies beyond blood pressure reduction--the role of angiotensin II antagonists
    P R Conlin
    Endocrinology, Diabetes and Hypertension Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Int J Clin Pract 59:214-24. 2005
  3. ncbi request reprint Interactions of high salt intake and the response of the cardiovascular system to aldosterone
    Paul R Conlin
    Division of Endocrinology, Diabetes and Hypertension Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cardiol Rev 13:118-24. 2005
  4. ncbi request reprint The DASH diet enhances the blood pressure response to losartan in hypertensive patients
    Paul R Conlin
    Division of Endocrinology, Diabetes and Hypertension PRC, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Am J Hypertens 16:337-42. 2003
  5. ncbi request reprint Benefits of angiotensin converting enzyme inhibition and angiotensin II receptor antagonists in hypertension
    P R Conlin
    Endocrinology Hypertension Division, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA
    J Med Liban 48:382-6. 2000
  6. ncbi request reprint Rationale and design of the Optimal Macro-Nutrient Intake Heart Trial to Prevent Heart Disease (OMNI-Heart)
    Vincent J Carey
    Channing Laboratory, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Clin Trials 2:529-37. 2005
  7. ncbi request reprint Changes in aortic stiffness and augmentation index after acute converting enzyme or vasopeptidase inhibition
    Gary F Mitchell
    Cardiovascular Engineering, Inc, Waltham, MA 02453, USA
    Hypertension 46:1111-7. 2005
  8. ncbi request reprint Effects of protein, monounsaturated fat, and carbohydrate intake on blood pressure and serum lipids: results of the OmniHeart randomized trial
    Lawrence J Appel
    Welch Center for Prevention, Epidemiology and Clinical Research, Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205 2223, USA
    JAMA 294:2455-64. 2005
  9. pmc Web-based care management in patients with poorly controlled diabetes
    Graham T McMahon
    Division of Endocrinology, Diabetes and Hypertension, Brigham and Women s Hospital, Boston, MA, USA
    Diabetes Care 28:1624-9. 2005
  10. ncbi request reprint A randomized trial comparing intensive and passive education in patients with diabetes mellitus
    Annaswamy Raji
    Endocrinology Hypertension Division, Brigham and Women s Hospital, 221 Longwood Ave, Boston, MA 02115, USA
    Arch Intern Med 162:1301-4. 2002

Research Grants

Detail Information

Publications23

  1. ncbi request reprint Dietary modification and changes in blood pressure
    P R Conlin
    Endocrinology Hypertension Division, Brigham and Women s Hospital, Medical Service, VA Boston Healthcare Syste, Boston, Massachusetts 02115, USA
    Curr Opin Nephrol Hypertens 10:359-63. 2001
    ..This reaffirms the role of lifestyle modifications as both preventative and adjunctive means to lower blood pressure...
  2. ncbi request reprint Redefining efficacy of antihypertensive therapies beyond blood pressure reduction--the role of angiotensin II antagonists
    P R Conlin
    Endocrinology, Diabetes and Hypertension Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Int J Clin Pract 59:214-24. 2005
    ..The results of these AIIA outcome trials have impacted on recently issued clinical guidelines for management of hypertension...
  3. ncbi request reprint Interactions of high salt intake and the response of the cardiovascular system to aldosterone
    Paul R Conlin
    Division of Endocrinology, Diabetes and Hypertension Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cardiol Rev 13:118-24. 2005
    ..Thus, aldosterone blockade with mineralocorticoid receptor antagonists offers target organ protection and may blunt some of the adverse effects of chronic high salt intake...
  4. ncbi request reprint The DASH diet enhances the blood pressure response to losartan in hypertensive patients
    Paul R Conlin
    Division of Endocrinology, Diabetes and Hypertension PRC, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Am J Hypertens 16:337-42. 2003
    ..We conducted a clinical trial to assess the BP response to the DASH diet with an antihypertensive medication, losartan, in participants with essential hypertension...
  5. ncbi request reprint Benefits of angiotensin converting enzyme inhibition and angiotensin II receptor antagonists in hypertension
    P R Conlin
    Endocrinology Hypertension Division, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA
    J Med Liban 48:382-6. 2000
    ..The review has illustrated specific clinical conditions where the use of an hypertensive agent that inhibits the renin-angiotensin system may offer added benefit to the patient while producing the needed anti-hypertensive effects...
  6. ncbi request reprint Rationale and design of the Optimal Macro-Nutrient Intake Heart Trial to Prevent Heart Disease (OMNI-Heart)
    Vincent J Carey
    Channing Laboratory, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Clin Trials 2:529-37. 2005
    ..Whether partial replacement of some carbohydrate (C) with either protein (P) or unsaturated fat (U) can further improve these and other cardiovascular (CVD) risk factors is unknown...
  7. ncbi request reprint Changes in aortic stiffness and augmentation index after acute converting enzyme or vasopeptidase inhibition
    Gary F Mitchell
    Cardiovascular Engineering, Inc, Waltham, MA 02453, USA
    Hypertension 46:1111-7. 2005
    ..Our findings indicate that AI is a complex surrogate marker that is inversely related to changes in proximal aortic stiffness in systolic hypertension...
  8. ncbi request reprint Effects of protein, monounsaturated fat, and carbohydrate intake on blood pressure and serum lipids: results of the OmniHeart randomized trial
    Lawrence J Appel
    Welch Center for Prevention, Epidemiology and Clinical Research, Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205 2223, USA
    JAMA 294:2455-64. 2005
    ..Reduced intake of saturated fat is widely recommended for prevention of cardiovascular disease. The type of macronutrient that should replace saturated fat remains uncertain...
  9. pmc Web-based care management in patients with poorly controlled diabetes
    Graham T McMahon
    Division of Endocrinology, Diabetes and Hypertension, Brigham and Women s Hospital, Boston, MA, USA
    Diabetes Care 28:1624-9. 2005
    ..To assess the effects of web-based care management on glucose and blood pressure control over 12 months in patients with poorly controlled diabetes...
  10. ncbi request reprint A randomized trial comparing intensive and passive education in patients with diabetes mellitus
    Annaswamy Raji
    Endocrinology Hypertension Division, Brigham and Women s Hospital, 221 Longwood Ave, Boston, MA 02115, USA
    Arch Intern Med 162:1301-4. 2002
    ..Patient education is a cornerstone of treatment in diabetes mellitus, but there is not unanimity of opinion as to how it should be delivered...
  11. ncbi request reprint Effect of the dietary approaches to stop hypertension diet and reduced sodium intake on blood pressure control
    Laura P Svetkey
    Duke Hypertension Center, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Hypertens (Greenwich) 6:373-81. 2004
    ..BP became normal or optimal in 71% of persons consuming the control/lower sodium diet and 77% of persons consuming the DASH/lower sodium diet. Both the DASH diet and reduced sodium intake improved BP control...
  12. ncbi request reprint Dietary sodium intake modulates myocardial relaxation responsiveness to angiotensin II
    Jonathan S Williams
    Division of Endocrinology, Diabetes and Hypertension, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02115, USA
    Transl Res 148:49-54. 2006
    ..Ang II may play a role in the interaction between dietary sodium and myocardial relaxation. Future research will investigate whether abnormalities in these mechanisms play a role in disorders of diastolic function...
  13. ncbi request reprint Web-based education in systems-based practice: a randomized trial
    B Price Kerfoot
    Urology Section, Veterans Affairs Boston Healthcare System, Harvard Medical School, and Endocrinology, Diabetes, and Hypertension Division, Brigham and Women s Hospital, Boston, Mass 02130, USA
    Arch Intern Med 167:361-6. 2007
    ..Medical schools are now adopting similar competency frameworks. We investigated whether a Web-based program could effectively teach and assess elements of systems-based practice...
  14. ncbi request reprint Practitioner-level determinants of inappropriate prostate-specific antigen screening
    B Price Kerfoot
    VA Boston Healthcare System, 150 S Huntington Ave, 151DIA, Jamaica Plain, MA 02130, USA
    Arch Intern Med 167:1367-72. 2007
    ..We investigated the practitioner-level determinants of inappropriate PSA screening in 7 Veterans Health Administration (VHA) hospitals...
  15. ncbi request reprint Framework for a national teleretinal imaging program to screen for diabetic retinopathy in Veterans Health Administration patients
    Paul R Conlin
    Endocrinology Section, Department of Veterans Affairs VA Boston Healthcare System, Boston, MA 02130, USA
    J Rehabil Res Dev 43:741-8. 2006
    ....
  16. ncbi request reprint Eat your fruits and vegetables but hold the salt
    Paul R Conlin
    Circulation 116:1530-1. 2007
  17. ncbi request reprint Aortic diameter, wall stiffness, and wave reflection in systolic hypertension
    Gary F Mitchell
    Cardiovascular Engineering Inc, University Office Park, Bldg 2, Suite 100, 51 Sawyer Road, Waltham, MA 02453, USA
    Hypertension 51:105-11. 2008
    ..Among individuals with systolic hypertension, increased PP is primarily attributable to increased wall stiffness and reduced aortic diameter rather than premature wave reflection...
  18. ncbi request reprint Red blood cell Na+/H+ exchange activity is insulin resistant in hypertensive patients
    Jose R Romero
    Endocrinology Hypertension Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Clin Exp Hypertens 24:277-87. 2002
    ..Hypertensive patients have elevated basal NHE activity but a blunted response to insulin suggesting that RBC may be a model to study insulin resistance in essential hypertensive patients...
  19. ncbi request reprint Successfully recruiting a multicultural population: the DASH-Sodium experience
    Betty M Kennedy
    Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA
    Ethn Dis 15:123-9. 2005
    ..Although the most successful method of recruitment was mass mailing brochures, three times as many brochures were distributed to obtain similar success as in the initial DASH trial...
  20. ncbi request reprint Effect of dietary sodium intake on blood lipids: results from the DASH-sodium trial
    David W Harsha
    Pennington Biomedical Research Center, Baton Rouge, LA, USA
    Hypertension 43:393-8. 2004
    ..There were no significant interactions between the effects of sodium and the DASH diet on serum lipids. In conclusion, changes in dietary sodium intake over the range of 50 to 150 mmol/d did not affect blood lipid concentrations...
  21. ncbi request reprint Sodium and blood pressure: no data dredging, please!
    Frank M Sacks
    Am J Hypertens 16:614-6. 2003
  22. ncbi request reprint Effects of the Dietary Approaches to Stop Hypertension (DASH) diet on the pressure-natriuresis relationship
    Sachie Akita
    Department of Internal Medicine and Pathophysiology, Nagoya City University Graduate School of Medical Sciences, Mizuho cho, Mizuho ku, Nagoya 467 8601, Japan
    Hypertension 42:8-13. 2003
    ..5+/-3.4 vs 64.9+/-13.1 [mmol/d]/mm Hg, P=0.0002) without significantly shifting the x-intercept (94.1+/-0.5 vs 93.2+/-0.6 mm Hg, NS) of the relationship. These data suggest a natriuretic action of the DASH diet...
  23. ncbi request reprint Genes and environment in blood pressure control--salt intake again shows its importance
    Paul R Conlin
    Am J Clin Nutr 88:255-6. 2008

Research Grants1

  1. Cardiovascular and renal hemodynamics and the DASH diet
    Paul Conlin; Fiscal Year: 2009
    ..abstract_text> ..