Justine A Barletta

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. doi request reprint Immunohistochemical staining of thyroidectomy specimens for PTEN can aid in the identification of patients with Cowden syndrome
    Justine A Barletta
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Surg Pathol 35:1505-11. 2011
  2. doi request reprint Molecular alterations in partially-encapsulated or well-circumscribed follicular variant of papillary thyroid carcinoma
    Brooke E Howitt
    1 Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts
    Thyroid 23:1256-62. 2013
  3. doi request reprint Immunohistochemistry using the BRAF V600E mutation-specific monoclonal antibody VE1 is not a useful surrogate for genotyping in colorectal adenocarcinoma
    Cheryl A Adackapara
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Histopathology 63:187-93. 2013
  4. doi request reprint The Impact of Noninvasive Follicular Variant of Papillary Thyroid Carcinoma on Rates of Malignancy for Fine-Needle Aspiration Diagnostic Categories
    Kyle C Strickland
    1 Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts
    Thyroid 25:987-92. 2015
  5. doi request reprint Clinicopathologic characteristics of malignant mesotheliomas arising in patients with a history of radiation for Hodgkin and non-Hodgkin lymphoma
    Lucian R Chirieac
    Lucian R Chirieac, Justine A Barletta, William G Richards, Tamara Tilleman, Raphael Bueno, Elizabeth H Baldini, John Godleski, and David J Sugarbaker, Brigham and Women s Hospital Beow Y Yeap, Massachusetts General Hospital and William G Richards, Tamara Tilleman, Raphael Bueno, Elizabeth H Baldini, and David J Sugarbaker, Harvard Medical School, Boston, MA
    J Clin Oncol 31:4544-9. 2013
  6. doi request reprint Risk stratification of follicular variant of papillary thyroid carcinoma
    Marina Vivero
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Thyroid 23:273-9. 2013
  7. pmc The variable phenotype and low-risk nature of RAS-positive thyroid nodules
    Marco Medici
    Thyroid Section, Division of Endocrinology, Hypertension and Diabetes, The Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, PBB B4 Room 417, Boston, MA, 02115, USA
    BMC Med 13:184. 2015
  8. doi request reprint Targeted genomic profiling reveals recurrent KRAS mutations and gain of chromosome 1q in mesonephric carcinomas of the female genital tract
    Jelena Mirkovic
    Department of Pathology, Brigham and Women s Hospital, Boston, MA, USA
    Mod Pathol 28:1504-14. 2015
  9. doi request reprint Identification of succinate dehydrogenase-deficient bladder paragangliomas
    Emily F Mason
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School Department of Pathology, Massachusetts General Hospital, Harvard Medical School Dana Farber Cancer Institute, Center for Sarcoma and Bone Oncology, Harvard Medical School, Boston, MA Department of Pathology, The Ottawa Hospital, Ottawa, ON, Canada
    Am J Surg Pathol 37:1612-8. 2013
  10. doi request reprint A comprehensive analysis of PAX8 expression in human epithelial tumors
    Anna R Laury
    Department of Pathology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Am J Surg Pathol 35:816-26. 2011

Collaborators

Detail Information

Publications17

  1. doi request reprint Immunohistochemical staining of thyroidectomy specimens for PTEN can aid in the identification of patients with Cowden syndrome
    Justine A Barletta
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Surg Pathol 35:1505-11. 2011
    ..3%, respectively. In summary, loss of PTEN expression in adenomatous thyroid nodules, whether in all nodules or in a subset of nodules, appears to be both sensitive and specific for CS...
  2. doi request reprint Molecular alterations in partially-encapsulated or well-circumscribed follicular variant of papillary thyroid carcinoma
    Brooke E Howitt
    1 Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts
    Thyroid 23:1256-62. 2013
    ..We have previously reported that PE/WC FVPTCs behave in an indolent fashion similar to encapsulated tumors. The purpose of the current study was to evaluate the molecular alterations in PE/WC FVPTC...
  3. doi request reprint Immunohistochemistry using the BRAF V600E mutation-specific monoclonal antibody VE1 is not a useful surrogate for genotyping in colorectal adenocarcinoma
    Cheryl A Adackapara
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Histopathology 63:187-93. 2013
    ..A BRAF V600E-specific antibody has recently become commercially available. The aim of this study was to determine whether immunohistochemistry can predict BRAF mutations in CRC...
  4. doi request reprint The Impact of Noninvasive Follicular Variant of Papillary Thyroid Carcinoma on Rates of Malignancy for Fine-Needle Aspiration Diagnostic Categories
    Kyle C Strickland
    1 Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts
    Thyroid 25:987-92. 2015
    ..Therefore, the aim of this study was to determine the percentage decrease in associated risk of malignancy for each FNA diagnostic category if NFVPTCs were no longer termed carcinomas...
  5. doi request reprint Clinicopathologic characteristics of malignant mesotheliomas arising in patients with a history of radiation for Hodgkin and non-Hodgkin lymphoma
    Lucian R Chirieac
    Lucian R Chirieac, Justine A Barletta, William G Richards, Tamara Tilleman, Raphael Bueno, Elizabeth H Baldini, John Godleski, and David J Sugarbaker, Brigham and Women s Hospital Beow Y Yeap, Massachusetts General Hospital and William G Richards, Tamara Tilleman, Raphael Bueno, Elizabeth H Baldini, and David J Sugarbaker, Harvard Medical School, Boston, MA
    J Clin Oncol 31:4544-9. 2013
    ..The clinicopathologic characteristics of malignant mesotheliomas arising in these patients have not been established...
  6. doi request reprint Risk stratification of follicular variant of papillary thyroid carcinoma
    Marina Vivero
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Thyroid 23:273-9. 2013
    ..Thus, the aim of this study was to investigate the metastatic potential and recurrence risk of PE/WC FVPTCs in comparison with that of encapsulated and infiltrative tumors...
  7. pmc The variable phenotype and low-risk nature of RAS-positive thyroid nodules
    Marco Medici
    Thyroid Section, Division of Endocrinology, Hypertension and Diabetes, The Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, PBB B4 Room 417, Boston, MA, 02115, USA
    BMC Med 13:184. 2015
    ..No long-term study of RAS-positive thyroid nodules has been performed...
  8. doi request reprint Targeted genomic profiling reveals recurrent KRAS mutations and gain of chromosome 1q in mesonephric carcinomas of the female genital tract
    Jelena Mirkovic
    Department of Pathology, Brigham and Women s Hospital, Boston, MA, USA
    Mod Pathol 28:1504-14. 2015
    ..Targeting inhibitors of the RAS/MAPK pathway may be useful in the treatment of mesonephric carcinoma. ..
  9. doi request reprint Identification of succinate dehydrogenase-deficient bladder paragangliomas
    Emily F Mason
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School Department of Pathology, Massachusetts General Hospital, Harvard Medical School Dana Farber Cancer Institute, Center for Sarcoma and Bone Oncology, Harvard Medical School, Boston, MA Department of Pathology, The Ottawa Hospital, Ottawa, ON, Canada
    Am J Surg Pathol 37:1612-8. 2013
    ..A significant subset of bladder paragangliomas is SDH deficient. It is essential to identify SDH-deficient tumors, as the presence of an SDH mutation has prognostic implications and is important in guiding genetic counseling. ..
  10. doi request reprint A comprehensive analysis of PAX8 expression in human epithelial tumors
    Anna R Laury
    Department of Pathology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Am J Surg Pathol 35:816-26. 2011
    ..In a subset of cases, additional markers, including but not limited to thyroid transcription factor-1, RCC, and Wilms tumor-1, may be needed to distinguish between the 3 most common PAX8-positive tumors...
  11. doi request reprint GATA3 expression in gestational trophoblastic tissues and tumours
    Jelena Mirkovic
    Department of Pathology, Women s and Perinatal Pathology Division, Brigham and Women s Hospital, Boston, MA, USA
    Histopathology 67:636-44. 2015
    ..GATA3 is sensitive for urothelial and breast carcinomas, but the specificity is low. The aim of this study was to investigate the expression of GATA3 in trophoblast-related tissues and neoplasia...
  12. doi request reprint Fine-needle aspiration diagnoses of noninvasive follicular variant of papillary thyroid carcinoma
    Brooke E Howitt
    From the Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, and
    Am J Clin Pathol 144:850-7. 2015
    ..A change in terminology would affect cytology diagnoses; thus, our aim was to study the preceding fine-needle aspiration (FNA) diagnoses of this group of tumors...
  13. pmc Thyroid-specific knockout of the tumor suppressor mitogen-inducible gene 6 activates epidermal growth factor receptor signaling pathways and suppresses nuclear factor-κB activity
    Chi Iou Lin
    Department of Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
    Surgery 150:1295-302. 2011
    ..Mitogen-inducible gene 6 (Mig-6) is a putative tumor suppressor gene and prognostic biomarker in papillary thyroid cancer. We hypothesized that Mig-6 knockout would activate pro-oncogenic signaling in mouse thyrocytes...
  14. doi request reprint GATA3 Is a Sensitive and Specific Marker of Benign and Malignant Mesonephric Lesions in the Lower Female Genital Tract
    Brooke E Howitt
    Department of Pathology, Division of Women s and Perinatal Pathology, Brigham and Women s Hospital Harvard Medical School Department of Medical Oncology, Dana Farber Cancer Institute Department of Pathology, Massachusetts General Hospital, Boston, MA Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland, United Kingdom
    Am J Surg Pathol 39:1411-9. 2015
    ..In addition, GATA3 can aid in distinguishing lower genital mesonephric lesions from usual-type and gastric-type ENDO-CAs and uterine EM-CAs. ..
  15. pmc Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus
    Scott J Rodig
    Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    J Clin Invest 122:4645-53. 2012
    ..These results indicate that MCPyV is present in MCC tumors more frequently than previously reported and that mutations in TP53 tend to occur in MCC tumors that fail to express MCPyV large T antigen...
  16. doi request reprint Succinate dehydrogenase-deficient tumors: diagnostic advances and clinical implications
    Justine A Barletta
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Adv Anat Pathol 19:193-203. 2012
    ..This review will outline the genetics of SDH-deficient tumors, discuss possible mechanisms of tumorigenesis, and describe how these tumors can be identified by immunohistochemistry...
  17. pmc Sox2 protein expression is an independent poor prognostic indicator in stage I lung adenocarcinoma
    Lynette M Sholl
    Department of Pathology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am J Surg Pathol 34:1193-8. 2010
    ..5; 95% CI 1.2-5.1), but not in women. Sox2 seems to be an independent predictor of poor outcome in stage I lung adenocarcinomas and may help stratify patients at increased risk for recurrence...