Audrey P Gasch
Affiliation: Lawrence Berkeley National Laboratory
- The genomics of yeast responses to environmental stress and starvationAudrey P Gasch
Department of Genome Science, Lawrence Berkeley National Laboratory, 1 Cyclotron Road 84 355, Berkeley, CA 94720, USA
Funct Integr Genomics 2:181-92. 2002..The results of these studies present insights as to how yeast cells sense and respond to each new environment, and suggest mechanisms that this organism uses to survive stressful environmental changes...
- Flexible promoter architecture requirements for coactivator recruitmentDerek Y Chiang
Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA
BMC Mol Biol 7:16. 2006..We characterized the components of promoter architecture that govern the yeast transcription factors Cbf1 and Met31/32, which bind independently, but collaboratively recruit the coactivator Met4...
- Conservation and evolution of cis-regulatory systems in ascomycete fungiAudrey P Gasch
Genome Sciences Department, Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA
PLoS Biol 2:e398. 2004..Our results suggest that the DNA binding specificity of these proteins has coevolved with the sequences found upstream of the Rpn4p target genes and suggest that Rpn4p has a different function in N. crassa...
- Exploring the conditional coregulation of yeast gene expression through fuzzy k-means clusteringAudrey P Gasch
Department of Genome Science, Life Science Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
Genome Biol 3:RESEARCH0059. 2002..Because most commonly used analytical methods cannot appropriately represent these relationships, the connections between conditionally coregulated genes are often missed...
- Comparative genomics of the environmental stress response in ascomycete fungiAudrey P Gasch
Laboratory of Genetics and Genome Center of Wisconsin, University of Wisconsin Madison, Madison, WI 53706, USA
Yeast 24:961-76. 2007..Implications for the role of this response, based on its presence or absence in fungi from disparate ecological niches, are discussed...
- Genome-wide analysis of gene expression regulated by the calcineurin/Crz1p signaling pathway in Saccharomyces cerevisiaeHiroyuki Yoshimoto
Department of Biological Sciences, Stanford University, 371 Serra Mall, Stanford, CA 94305 5020, USA
J Biol Chem 277:31079-88. 2002..A similar sequence, 5'-GAGGCTG-3', was identified as a common sequence motif in the upstream regions of calcineurin/ Crz1p-dependent genes. This finding is consistent with direct regulation of these genes by Crz1p...
- Methionine sulfoxide reductase regulation of yeast lifespan reveals reactive oxygen species-dependent and -independent components of agingAhmet Koc
Department of Biochemistry, University of Nebraska, Lincoln, NE 68588 0664, USA
Proc Natl Acad Sci U S A 101:7999-8004. 2004..The data also suggest a model wherein factors implicated in aging (for example, ROS) may influence the lifespan yet not be the cause of aging...
- Variations in stress sensitivity and genomic expression in diverse S. cerevisiae isolatesDaniel J Kvitek
Laboratory of Genetics, University of Wisconsin Madison, Madison, Wisconsin, United States of America
PLoS Genet 4:e1000223. 2008..These results highlight the value of understanding the genetic basis of phenotypic variation and raise caution about using laboratory strains for comparative genomics...