Affiliation: Lankenau Institute for Medical Research
- Protein kinase C activation leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheetsH Clarke
Lankenau Medical Research Center, Wynnewood, PA 19096, USA
J Cell Sci 113:3187-96. 2000....
- Regulation of protein kinase C-delta and -epsilon isoforms by phorbol ester treatment of LLC-PK1 renal epitheliaH Clarke
Lankenau Medical Research Center, Wynnewood, Pennsylvania, USA
Kidney Int 58:1004-15. 2000..Protein kinase C (PKC) has been observed to play a role in both processes. This study examines the subcellular distribution and down-regulation of PKC-delta and PKC-epsilon isoforms in phorbol ester-treated LLC-PK1 epithelia...
- The transient increase of tight junction permeability induced by bryostatin 1 correlates with rapid downregulation of protein kinase C-alphaH Clarke
Lankenau Medical Research Institute, 100 Lancaster Avenue, Wynnewood, Pennsylvania 19096, USA
Exp Cell Res 261:239-49. 2000..Due to its transient effect on tight junction permeability, bryostatin 1 offers a novel pharmacological tool to investigate junctional physiology...