Douglas S Reintgen

Summary

Affiliation: Lakeland Regional Cancer Center
Country: USA

Publications

  1. ncbi request reprint Current status of sentinel lymph node mapping and biopsy: facts and controversies
    James W Jakub
    The Lakeland Regional Cancer Center, Lakeland, Florida 33804, USA
    Oncologist 8:59-68. 2003
  2. ncbi request reprint The staging of malignant melanoma and the Florida Melanoma Trial
    Douglas S Reintgen
    Cutaneous Oncology Program, Lakeland Regional Cancer Center, Lakeland, Florida, USA
    Ann Surg Oncol 11:186S-91S. 2004
  3. ncbi request reprint Melanoma patients with positive sentinel nodes who did not undergo completion lymphadenectomy: a multi-institutional study
    Sandra L Wong
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
    Ann Surg Oncol 13:809-16. 2006
  4. ncbi request reprint Regional node dissection for melanoma: techniques and indication
    James W Jakub
    Cutaneous Oncology Program, Lakeland Regional Cancer Center, 3525 Lakeland Hills Blvd, P O Box 91057, Lakeland, FL 33805 1057, USA
    Surg Oncol Clin N Am 16:247-61. 2007
  5. doi request reprint Full-thickness grafts procured from skin overlying the sentinel lymph node basin; reconstruction of primary cutaneous malignancy excision defects
    James M Lewis
    Department of Oncologic Sciences, University of South Florida, Tampa, FL, USA
    Ann Surg Oncol 15:1733-40. 2008
  6. pmc Regional Therapy for Recurrent Metastatic Melanoma Confined to the Extremity: Hyperthermic Isolated Limb Perfusion vs. Isolated Limb Infusion
    Michael Reintgen
    Cutaneous Oncology Program, Lakeland Regional Cancer Center, Lakeland, FL 33804 1057, USA
    Cancers (Basel) 2:43-50. 2010
  7. ncbi request reprint Worldwide experience with lymphatic mapping for invasive breast cancer
    Solange Pendas
    Lakeland Regional Cancer Center, FL 33804 1057, USA
    Semin Oncol 31:318-23. 2004
  8. ncbi request reprint The role of sentinel lymph node biopsy in patients with ductal carcinoma in situ or with locally advanced breast cancer receiving neoadjuvant chemotherapy
    Solange Pendas
    Surgical Oncology, Lakeland Regional Cancer Center, FL 33804, USA
    Cancer Control 11:231-5. 2004
  9. ncbi request reprint A case report of invasive ductal adenocarcinoma identified in a lymphatic channel: a staging controversy
    James W Jakub
    Breast Program, Lakeland Regional Cancer Center, FL, USA
    Cancer Control 10:411-3. 2003
  10. pmc Effect of lymphatic mapping on diagnosis and treatment of patients with T1a, T1b favorable breast cancer
    James W Jakub
    Lakeland Regional Cancer Center, 300 Parkview Place, Lakeland, FL 33805, USA
    Ann Surg 237:838-41; discussion 841-3. 2003

Collaborators

Detail Information

Publications42

  1. ncbi request reprint Current status of sentinel lymph node mapping and biopsy: facts and controversies
    James W Jakub
    The Lakeland Regional Cancer Center, Lakeland, Florida 33804, USA
    Oncologist 8:59-68. 2003
    ..Despite the success and acceptance of lymphatic mapping, many controversies remain. We have attempted to clearly highlight these controversies in this review...
  2. ncbi request reprint The staging of malignant melanoma and the Florida Melanoma Trial
    Douglas S Reintgen
    Cutaneous Oncology Program, Lakeland Regional Cancer Center, Lakeland, Florida, USA
    Ann Surg Oncol 11:186S-91S. 2004
    ..The lymphatic mapping procedure is the most accurate way to determine the tumor status of the regional lymph nodes...
  3. ncbi request reprint Melanoma patients with positive sentinel nodes who did not undergo completion lymphadenectomy: a multi-institutional study
    Sandra L Wong
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
    Ann Surg Oncol 13:809-16. 2006
    ..This multi-institutional study was undertaken to characterize patterns of failure and survival rates in these patients and to compare results with those of positive-SLN patients who underwent CLND...
  4. ncbi request reprint Regional node dissection for melanoma: techniques and indication
    James W Jakub
    Cutaneous Oncology Program, Lakeland Regional Cancer Center, 3525 Lakeland Hills Blvd, P O Box 91057, Lakeland, FL 33805 1057, USA
    Surg Oncol Clin N Am 16:247-61. 2007
    ..Until further data are available, melanoma patients with a positive SLN by H&E analysis should proceed to a complete lymph node dissection...
  5. doi request reprint Full-thickness grafts procured from skin overlying the sentinel lymph node basin; reconstruction of primary cutaneous malignancy excision defects
    James M Lewis
    Department of Oncologic Sciences, University of South Florida, Tampa, FL, USA
    Ann Surg Oncol 15:1733-40. 2008
    ..However, the potential for implantation of malignant cells transferred from the nodal basin to the primary site, resulting in increased perigraft recurrence rates with the FTSG technique, has not been evaluated...
  6. pmc Regional Therapy for Recurrent Metastatic Melanoma Confined to the Extremity: Hyperthermic Isolated Limb Perfusion vs. Isolated Limb Infusion
    Michael Reintgen
    Cutaneous Oncology Program, Lakeland Regional Cancer Center, Lakeland, FL 33804 1057, USA
    Cancers (Basel) 2:43-50. 2010
    ..Ninty-two of the 229 patients (40%) had metastatic regional nodal disease documented at the time of the HILP procedure. HILP is the only technique that addresses all micrometastatic disease on the extremity. ..
  7. ncbi request reprint Worldwide experience with lymphatic mapping for invasive breast cancer
    Solange Pendas
    Lakeland Regional Cancer Center, FL 33804 1057, USA
    Semin Oncol 31:318-23. 2004
    ..Because of the low morbidity associated with the lymphatic mapping procedure, all women with invasive breast cancer should be considered as candidates for this more accurate staging technique...
  8. ncbi request reprint The role of sentinel lymph node biopsy in patients with ductal carcinoma in situ or with locally advanced breast cancer receiving neoadjuvant chemotherapy
    Solange Pendas
    Surgical Oncology, Lakeland Regional Cancer Center, FL 33804, USA
    Cancer Control 11:231-5. 2004
    ..The role of SLN biopsy after neoadjuvant chemotherapy in patients with advanced breast cancer is controversial...
  9. ncbi request reprint A case report of invasive ductal adenocarcinoma identified in a lymphatic channel: a staging controversy
    James W Jakub
    Breast Program, Lakeland Regional Cancer Center, FL, USA
    Cancer Control 10:411-3. 2003
  10. pmc Effect of lymphatic mapping on diagnosis and treatment of patients with T1a, T1b favorable breast cancer
    James W Jakub
    Lakeland Regional Cancer Center, 300 Parkview Place, Lakeland, FL 33805, USA
    Ann Surg 237:838-41; discussion 841-3. 2003
    ....
  11. ncbi request reprint Breast cancer in patients with prior augmentation: presentation, stage, and lymphatic mapping
    James W Jakub
    Lakeland Regional Cancer Center Lakeland, Fla 33805, USA
    Plast Reconstr Surg 114:1737-42. 2004
    ..This initial mode of detection does not appear to translate into a larger tumor size or worse prognosis. Breast conservation and lymphatic mapping can be performed successfully in previously augmented patients...
  12. ncbi request reprint Completion axillary lymph node dissection minimizes the likelihood of false negatives for patients with invasive breast carcinoma and cytokeratin positive only sentinel lymph nodes
    James W Jakub
    H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
    Am J Surg 184:302-6. 2002
    ....
  13. ncbi request reprint Frequency of nonsentinel lymph node metastasis in melanoma
    Kelly M McMasters
    Division of Surgical Oncology, Department of Surgery, University of Louisville, Louisville, Kentucky 40202, USA
    Ann Surg Oncol 9:137-41. 2002
    ..This analysis was performed to determine, among patients with positive SLNs, the rate of nodal metastasis found in nonsentinel nodes (NSNs)...
  14. ncbi request reprint Complications associated with sentinel lymph node biopsy for melanoma
    William R Wrightson
    Division of Surgical Oncology, Department of Surgery, University of Louisville, James Graham Brown Cancer Center, Kentucky, USA
    Ann Surg Oncol 10:676-80. 2003
    ..This analysis was performed to evaluate the morbidity associated with SLN biopsy compared with completion lymph node dissection (CLND)...
  15. pmc Sentinel node biopsy for early-stage melanoma: accuracy and morbidity in MSLT-I, an international multicenter trial
    Donald L Morton
    John Wayne Cancer Institute, Santa Monica, CA 90404, USA
    Ann Surg 242:302-11; discussion 311-3. 2005
    ....
  16. ncbi request reprint Is incisional biopsy of melanoma harmful?
    Robert C G Martin
    The Department of Surgery, University of Louisville, James Graham Brown Cancer Center, 315 East Broadway, Rm 313, Louisville, KY 40202, USA
    Am J Surg 190:913-7. 2005
    ....
  17. ncbi request reprint Accurate staging of women with breast cancer
    Christina J Kim
    J Surg Oncol 79:2-4. 2002
  18. ncbi request reprint Prospective multi-institutional study of reverse transcriptase polymerase chain reaction for molecular staging of melanoma
    Charles R Scoggins
    Division of Surgical Oncology, Department of Surgery, University of Louisville, James Graham Brown Cancer Center and Center for Advanced Surgical Technologies CAST, Louisville, KY 40292, USA
    J Clin Oncol 24:2849-57. 2006
    ..To evaluate the prognostic significance of molecular staging using reverse transcriptase polymerase chain reaction (RT-PCR) in detecting occult melanoma cells in sentinel lymph nodes (SLNs) and circulating bloodstream...
  19. ncbi request reprint Overall and progression-free survival in metastatic melanoma: analysis of a single-institution database
    M Aleem Khan
    Department of Cutaneous Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Cancer Control 13:211-7. 2006
    ..Since few trials in melanoma have had a non-treated cohort, it remains unclear what survival can be expected in patients who are not treated with chemotherapy...
  20. ncbi request reprint Sentinel-node biopsy or nodal observation in melanoma
    Donald L Morton
    Department of Surgical Oncology, John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, CA 90404, USA
    N Engl J Med 355:1307-17. 2006
    ..We evaluated the contribution of sentinel-node biopsy to outcomes in patients with newly diagnosed melanoma...
  21. ncbi request reprint Patterns of early recurrence after sentinel lymph node biopsy for melanoma
    Celia Chao
    Department of Surgery, Division of Surgical Oncology, James Graham Brown Cancer Center, University of Louisville, 315 East Broadway, Suite 309, KY 40202, USA
    Am J Surg 184:520-4; discussion 525. 2002
    ..Patterns of early recurrence after sentinel lymph node (SLN) biopsy for melanoma was determined from the Sunbelt Melanoma Trial, which includes patients with Breslow thickness > or =1.0 mm and nonpalpable regional lymph nodes...
  22. ncbi request reprint Surgical complications associated with sentinel lymph node dissection (SLND) plus axillary lymph node dissection compared with SLND alone in the American College of Surgeons Oncology Group Trial Z0011
    Anthony Lucci
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 25:3657-63. 2007
    ..The current study compares complications associated with SLN dissection (SLND) plus ALND, versus SLND alone...
  23. ncbi request reprint Factors associated with improved survival among young adult melanoma patients despite a greater incidence of sentinel lymph node metastasis
    Ryaz B Chagpar
    University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    J Surg Res 143:164-8. 2007
    ..We sought to evaluate the factors that affect sentinel lymph node (SLN) metastasis and survival among young melanoma patients (< or =30 y)...
  24. ncbi request reprint Lessons learned from the Sunbelt Melanoma Trial
    Kelly M McMasters
    The Department of Surgery, University of Louisville, James Graham Brown Cancer Center and Center for Advanced Surgical Technologies CAST, Louisville, Kentucky 40202, USA
    J Surg Oncol 86:212-23. 2004
    ..Future analyses will evaluate the benefit of early therapeutic lymphadenectomy and early institution of adjuvant interferon alfa-2b therapy, as well as the validity of molecular staging...
  25. ncbi request reprint An evidence-based staging system for cutaneous melanoma
    Charles M Balch
    American Society of Clinical Oncology, Alexandria, VA, USA
    CA Cancer J Clin 54:131-49; quiz 182-4. 2004
    ..6) A new convention was implemented for defining clinical and pathological staging so as to take into account the new staging information gained from lymphatic mapping and sentinel node biopsy...
  26. ncbi request reprint Sentinel lymph node biopsy for head and neck melanomas
    Celia Chao
    Division of Surgical Oncology, James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky 40202, USA
    Ann Surg Oncol 10:21-6. 2003
    ..This analysis was performed to compare the results of SLN biopsy for H&N, truncal, and extremity melanomas...
  27. ncbi request reprint Interval sentinel lymph nodes in melanoma
    Kelly M McMasters
    Division of Surgical Oncology, Department of Surgery, James Graham Brown Cancer Center, University of Louisvill, 529 S Jackson St, Louisville, KY 40202, USA
    Arch Surg 137:543-7; discussion 547-9. 2002
    ..For patients with melanoma, interval or in-transit sentinel lymph nodes (SLNs) have the same risk for nodal metastasis as SLN in traditional (ie, cervical, axillary, and inguinal) nodal basins...
  28. ncbi request reprint Prevalence of additional positive lymph nodes in complete lymphadenectomy specimens after positive sentinel lymphadenectomy findings for early-stage melanoma of the head and neck
    Lee L Q Pu
    Division of Plastic Surgery, University of South Florida, Tampa, USA
    Plast Reconstr Surg 112:43-9. 2003
    ..Nevertheless, the question of whether subsequent complete lymphadenectomy is still necessary for this subgroup of patients warrants further study...
  29. ncbi request reprint Superficial femoral lymph node dissection after positive sentinel lymphadenectomy for early-stage melanoma of the lower extremity
    Lee L Q Pu
    Division of Plastic Surgery, University of South Florida and the Cutaneous Oncology Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
    Ann Plast Surg 51:69-76. 2003
    ..However, whether the sentinel lymphadenectomy can be used solely as a regional surgical treatment for this subgroup of patients still warrants further evaluation...
  30. ncbi request reprint Metastatic melanoma: chemotherapy to biochemotherapy
    Steven J O'Day
    John Wayne Cancer Institute at St John s Health Center, Santa Monica, CA 90404, USA
    Cancer Control 9:31-8. 2002
    ..Biologic response modifiers (interferon and interleukin-2) have produced durable remissions in a small cohort of patients, and phase II trials of biochemotherapy suggest more benefit...
  31. ncbi request reprint New TNM melanoma staging system: linking biology and natural history to clinical outcomes
    Charles M Balch
    Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Semin Surg Oncol 21:43-52. 2003
    ....
  32. ncbi request reprint Reassessing the role of lymphatic mapping and sentinel lymphadenectomy in the management of cutaneous malignant melanoma
    Ronald E Perrott
    University of South Florida College of Medicine, Tampa, FL 33612 4719, USA
    J Am Acad Dermatol 49:567-88; quiz 589-92. 2003
    ..We review the latest technical aspects of this procedure and discuss the controversies surrounding its use...
  33. ncbi request reprint Age and body mass index may increase the chance of failure in sentinel lymph node biopsy for women with breast cancer
    Charles E Cox
    FACS, Comprehensive Breast Cancer Program, H Lee Moffitt Cancer Center and Research Institute, University of South Florida in Tampa, 12902 Magnolia Drive, Suite 2190, Tampa, FL 33612, USA
    Breast J 8:88-91. 2002
    ..However, increased age and/or BMI alone do not appear to be contraindications for SLN biopsy in older or overweight patients...
  34. ncbi request reprint The promise of new technologies and therapies
    Douglas S Reintgen
    Cancer Control 9:4-5. 2002
  35. pmc Gender-related differences in outcome for melanoma patients
    Charles R Scoggins
    Division of Surgical Oncology, Department of Surgery, University of Louisville, KY 40292, USA
    Ann Surg 243:693-8; discussion 698-700. 2006
    ..To better understand the factors associated with the well-established gender difference in survival for patients with melanoma...
  36. ncbi request reprint Correlation between prognostic factors and increasing age in melanoma
    Celia Chao
    Department of Surgery, Division of Surgical Oncology, James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky 40202, USA
    Ann Surg Oncol 11:259-64. 2004
    ..To gain further insight into this apparent paradox, we analyzed the relationship between age and other major prognostic factors...
  37. ncbi request reprint The new melanoma staging system
    Christina J Kim
    Department of Surgery, H Lee Moffitt Cancer Center and Research Institute at the University of South Florida, Tampa, USA
    Cancer Control 9:9-15. 2002
    ..Sentinel lymph node mapping defines a subset of patients with microscopic metastatic disease can be identified, offering greater accuracy in staging...
  38. ncbi request reprint Surgical complications associated with sentinel lymph node biopsy: results from a prospective international cooperative group trial
    Lee Gravatt Wilke
    Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA
    Ann Surg Oncol 13:491-500. 2006
    ..Surgical complications associated with the sentinel lymph node biopsy surgical procedure are reported...
  39. ncbi request reprint Molecular mechanisms of metastasis
    Dave S B Hoon
    Department of Molecular Oncology, John Wayne Cancer Institute, Santa Monica, CA 90404, USA
    Cancer Metastasis Rev 25:203-20. 2006
    ..The hope is that further unraveling of the direct and indirect molecular events of lymphatic metastasis will lead to new approaches in developing effective therapeutics...
  40. ncbi request reprint Immunotherapy for melanoma
    Christina J Kim
    Department of Surgery, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
    Cancer Control 9:22-30. 2002
    ..Interferon-a has been approved for adjuvant treatment of stage III melanoma with improved survival. New and more innovative approaches with improved efficacy are needed...
  41. doi request reprint Impact of immediate versus delayed axillary node dissection on surgical outcomes in breast cancer patients with positive sentinel nodes: results from American College of Surgeons Oncology Group Trials Z0010 and Z0011
    John A Olson
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Oncol 26:3530-5. 2008
    ..The impact of the timing of cALND on pathologic results and complications in these patients has not been examined...
  42. ncbi request reprint The promise of microarray technology in melanoma care
    Christina J Kim
    Department of Surgery, H Lee Moffitt Cancer Center and Research Institute at the University of South Florida, Tampa, USA
    Cancer Control 9:49-53. 2002
    ..These DNA alterations result in significant changes in gene expression that may now be measured and catalogued. The microarray technique screens and identifies expressed genes that may be responsible for tumorigenesis...