Max A Tischfield

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Distinct alpha- and beta-tubulin isotypes are required for the positioning, differentiation and survival of neurons: new support for the 'multi-tubulin' hypothesis
    Max A Tischfield
    Department of Neurology and Ophthalmology, Manten Center for Orphan Disease Research, Children s Hospital Boston, Harvard Medical School, MA, USA
    Biosci Rep 30:319-30. 2010
  2. pmc An inherited TUBB2B mutation alters a kinesin-binding site and causes polymicrogyria, CFEOM and axon dysinnervation
    Gustav Y Cederquist
    Department of Neurology, Boston Children s Hospital, Boston, MA, USA
    Hum Mol Genet 21:5484-99. 2012
  3. pmc Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidance
    Max A Tischfield
    Department of Neurology, Children s Hospital Boston, Boston, MA 02115, USA
    Cell 140:74-87. 2010
  4. pmc Loss of MAFB Function in Humans and Mice Causes Duane Syndrome, Aberrant Extraocular Muscle Innervation, and Inner-Ear Defects
    Jong G Park
    Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA Department of Neurology, Boston Children s Hospital, Boston, MA 02115, USA F M Kirby Neurobiology Center, Boston Children s Hospital, Boston, MA 02115, USA Department of Neurology, Harvard Medical School, Boston, MA 02115, USA Duke University School of Medicine, Durham, NC 27710, USA
    Am J Hum Genet 98:1220-7. 2016

Collaborators

Detail Information

Publications4

  1. pmc Distinct alpha- and beta-tubulin isotypes are required for the positioning, differentiation and survival of neurons: new support for the 'multi-tubulin' hypothesis
    Max A Tischfield
    Department of Neurology and Ophthalmology, Manten Center for Orphan Disease Research, Children s Hospital Boston, Harvard Medical School, MA, USA
    Biosci Rep 30:319-30. 2010
    ....
  2. pmc An inherited TUBB2B mutation alters a kinesin-binding site and causes polymicrogyria, CFEOM and axon dysinnervation
    Gustav Y Cederquist
    Department of Neurology, Boston Children s Hospital, Boston, MA, USA
    Hum Mol Genet 21:5484-99. 2012
    ..Together with previous studies, these findings highlight that β-tubulin isotypes function in both conserved and divergent ways to support proper human nervous system development...
  3. pmc Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidance
    Max A Tischfield
    Department of Neurology, Children s Hospital Boston, Boston, MA 02115, USA
    Cell 140:74-87. 2010
    ..These findings demonstrate that normal TUBB3 is required for axon guidance and maintenance in mammals...
  4. pmc Loss of MAFB Function in Humans and Mice Causes Duane Syndrome, Aberrant Extraocular Muscle Innervation, and Inner-Ear Defects
    Jong G Park
    Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA Department of Neurology, Boston Children s Hospital, Boston, MA 02115, USA F M Kirby Neurobiology Center, Boston Children s Hospital, Boston, MA 02115, USA Department of Neurology, Harvard Medical School, Boston, MA 02115, USA Duke University School of Medicine, Durham, NC 27710, USA
    Am J Hum Genet 98:1220-7. 2016
    ..Thus, we present evidence that the primary cause of DRS is failure of the abducens nerve to fully innervate the lateral rectus muscle in early development. ..