Larisa G Tereshchenko

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Transient local injury current in right ventricular electrogram after implantable cardioverter-defibrillator shock predicts heart failure progression
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    J Am Coll Cardiol 54:822-8. 2009
  2. pmc Ventricular arrhythmia is predicted by sum absolute QRST integralbut not by QRS width
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    J Electrocardiol 43:548-52. 2010
  3. pmc Infiltrated atrial fat characterizes underlying atrial fibrillation substrate in patients at risk as defined by the ARIC atrial fibrillation risk score
    Larisa G Tereshchenko
    The Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States Electronic address
    Int J Cardiol 172:196-201. 2014
  4. doi request reprint Electrocardiogram as a screening tool in the general population: a strategic review
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA Electronic address
    J Electrocardiol 46:553-6. 2013
  5. pmc ECG marker of adverse electrical remodeling post-myocardial infarction predicts outcomes in MADIT II study
    Larisa G Tereshchenko
    The Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    PLoS ONE 7:e51812. 2012
  6. pmc Predictive value of beat-to-beat QT variability index across the continuum of left ventricular dysfunction: competing risks of noncardiac or cardiovascular death and sudden or nonsudden cardiac death
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Circ Arrhythm Electrophysiol 5:719-27. 2012
  7. pmc Intracardiac J-point elevation before the onset of polymorphic ventricular tachycardia and ventricular fibrillation in patients with an implantable cardioverter-defibrillator
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, 600 N Wolfe St, Baltimore, MD 21287, USA
    Heart Rhythm 9:1594-602. 2012
  8. doi request reprint Strong coherence between heart rate variability and intracardiac repolarization lability during biventricular pacing is associated with reverse electrical remodeling of the native conduction and improved outcome
    Larisa G Tereshchenko
    The Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD, USA
    J Electrocardiol 44:713-7. 2011
  9. pmc A new electrocardiogram marker to identify patients at low risk for ventricular tachyarrhythmias: sum magnitude of the absolute QRST integral
    Larisa G Tereshchenko
    The Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD, USA
    J Electrocardiol 44:208-16. 2011
  10. doi request reprint Prediction of ventricular tachyarrhythmias by intracardiac repolarization variability analysis
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Circ Arrhythm Electrophysiol 2:276-84. 2009

Collaborators

Detail Information

Publications36

  1. pmc Transient local injury current in right ventricular electrogram after implantable cardioverter-defibrillator shock predicts heart failure progression
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    J Am Coll Cardiol 54:822-8. 2009
    ..This study aimed to identify an early marker of functional impairment after an implantable cardioverter-defibrillator (ICD) shock as a predictor of heart failure progression...
  2. pmc Ventricular arrhythmia is predicted by sum absolute QRST integralbut not by QRS width
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    J Electrocardiol 43:548-52. 2010
    ..We explored correlations between QRS width, SAI QRST, and VA in primary prevention implantable cardioverter-defibrillator (ICD) patients with structural heart disease...
  3. pmc Infiltrated atrial fat characterizes underlying atrial fibrillation substrate in patients at risk as defined by the ARIC atrial fibrillation risk score
    Larisa G Tereshchenko
    The Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States Electronic address
    Int J Cardiol 172:196-201. 2014
    ..It is known that expanded epicardial fat is associated with atrial fibrillation (AF). However, infiltrated intraatrial fat has not been previously quantified in individuals at risk as determined by the ARIC AF risk score...
  4. doi request reprint Electrocardiogram as a screening tool in the general population: a strategic review
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA Electronic address
    J Electrocardiol 46:553-6. 2013
    ..However, traditional analysis of ECG includes very limited assessment of the arrhythmogenic substrate. In this review rationale for development of ECG SCD risk score for screening in the general population is discussed. ..
  5. pmc ECG marker of adverse electrical remodeling post-myocardial infarction predicts outcomes in MADIT II study
    Larisa G Tereshchenko
    The Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    PLoS ONE 7:e51812. 2012
    ..Post-myocardial infarction (MI) structural remodeling is characterized by left ventricular dilatation, fibrosis, and hypertrophy of the non-infarcted myocardium...
  6. pmc Predictive value of beat-to-beat QT variability index across the continuum of left ventricular dysfunction: competing risks of noncardiac or cardiovascular death and sudden or nonsudden cardiac death
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Circ Arrhythm Electrophysiol 5:719-27. 2012
    ..The goal of the present study was to determine the predictive value of beat-to-beat QT variability in heart failure patients across the continuum of left ventricular dysfunction...
  7. pmc Intracardiac J-point elevation before the onset of polymorphic ventricular tachycardia and ventricular fibrillation in patients with an implantable cardioverter-defibrillator
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, 600 N Wolfe St, Baltimore, MD 21287, USA
    Heart Rhythm 9:1594-602. 2012
    ..The clinical importance of the J-point elevation on electrocardiogram is controversial...
  8. doi request reprint Strong coherence between heart rate variability and intracardiac repolarization lability during biventricular pacing is associated with reverse electrical remodeling of the native conduction and improved outcome
    Larisa G Tereshchenko
    The Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD, USA
    J Electrocardiol 44:713-7. 2011
    ..Still, mechanisms of RER are largely unknown. In this study, we explored repolarization lability during biventricular pacing...
  9. pmc A new electrocardiogram marker to identify patients at low risk for ventricular tachyarrhythmias: sum magnitude of the absolute QRST integral
    Larisa G Tereshchenko
    The Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD, USA
    J Electrocardiol 44:208-16. 2011
    ..We proposed and tested a novel electrocardiogram marker of risk of ventricular arrhythmias (VAs)...
  10. doi request reprint Prediction of ventricular tachyarrhythmias by intracardiac repolarization variability analysis
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Circ Arrhythm Electrophysiol 2:276-84. 2009
    ....
  11. pmc Beat-to-beat three-dimensional ECG variability predicts ventricular arrhythmia in ICD recipients
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA
    Heart Rhythm 7:1606-13. 2010
    ..Methodological difficulties associated with QT measurements prompt the search for new electrocardiographic markers of repolarization heterogeneity...
  12. doi request reprint Antiarrhythmic effect of reverse electrical remodeling associated with cardiac resynchronization therapy
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Pacing Clin Electrophysiol 34:357-64. 2011
    ..We hypothesized that reverse electrical remodeling (RER) with CRT is associated with reduced frequency of ventricular tachyarrhythmias (VTs)...
  13. doi request reprint Intracardiac QT integral on far-field ICD electrogram predicts sustained ventricular tachyarrhythmias in ICD patients
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA
    Heart Rhythm 8:1889-94. 2011
    ..Prediction of sustained ventricular tachycardia (VT)/ventricular fibrillation (VF) could help to guide preventive interventions in at-risk patients. The QRST integral (∫QT) reflects intrinsic repolarization properties...
  14. pmc Number of P-wave fragmentations on P-SAECG correlates with infiltrated atrial fat
    Sindhoora Murthy
    Whiting School of Engineering, Johns Hopkins University, Baltimore, MD
    Ann Noninvasive Electrocardiol 19:114-21. 2014
    ..The goal of our study was to explore correlations between electrophysiological and structural characteristics of atria in patients with paroxysmal AF and individuals at AF risk...
  15. pmc Appropriate and inappropriate electrical therapies delivered by an implantable cardioverter-defibrillator: effect on intracardiac electrogram
    Peter Stempniewicz
    Whiting School of Engineering, The Johns Hopkins University, Baltimore, Maryland, USA
    J Cardiovasc Electrophysiol 22:554-60. 2011
    ..We sought to determine the frequency of LIC after spontaneous events in patients receiving ICD therapies...
  16. doi request reprint Intracardiac QT variability in patients with structural heart disease on class III antiarrhythmic drugs
    Larisa G Tereshchenko
    The Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, 600 N Wolfe Street, Baltimore, MD 21287, USA
    J Electrocardiol 42:505-10. 2009
    ..Increased intracardiac QT variability after adjustment for class III AADs use carried independent risk of life-threatening ventricular tachyarrhythmias...
  17. pmc Screening for Cardiac Magnetic Resonance Scar Features by 12-Lead ECG, in Patients with Preserved Ejection Fraction
    Nathan Mewton
    Division of Cardiology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD
    Ann Noninvasive Electrocardiol 21:49-59. 2016
    ..Our main objective was to assess whether a QRS score ≥ 5 and/or QRS-T angle ≥ 105° enable screening of patients for myocardial scar features...
  18. doi request reprint QT variability paradox after premature ventricular contraction in patients with structural heart disease and ventricular arrhythmias
    Durgesh Das
    Whiting School of Engineering, The Johns Hopkins University, Baltimore, MD, USA
    J Electrocardiol 45:652-7. 2012
    ..Premature ventricular contractions (PVCs) are excluded from the analysis of QT variability. However, QT dynamics after PVCs is poorly understood...
  19. pmc Comparison of sum absolute QRST integral, and temporal variability in depolarization and repolarization, measured by dynamic vectorcardiography approach, in healthy men and women
    Sanjoli Sur
    Whiting School of Engineering, The Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS ONE 8:e57175. 2013
    ..The goal of this study was to compare SAI QRST and metrics of depolarization and repolarization variability in healthy men and women...
  20. doi request reprint Mechanical alternans is associated with mortality in acute hospitalized heart failure: prospective mechanical alternans study (MAS)
    Robert Kim
    Whiting School of Engineering, The Johns Hopkins University, Baltimore, MD
    Circ Arrhythm Electrophysiol 7:259-66. 2014
    ..Timely (before hospital discharge) risk stratification of patients with AHHF is crucial. We hypothesized that mechanical alternans (MA) and T-wave alternans (TWA) are associated with postdischarge outcomes in patients with AHHF...
  21. pmc Arrhythmia risk stratification based on QT interval instability: an intracardiac electrocardiogram study
    Xiaozhong Chen
    Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland 21218, USA
    Heart Rhythm 10:875-80. 2013
    ..Experimental studies have demonstrated that unstable repolarization dynamics is a risk factor of arrhythmia. We have recently developed an algorithm to detect QT interval (QTI) instability from the clinical electrocardiogram (ECG)...
  22. pmc Associations of electrocardiographic P-wave characteristics with left atrial function, and diffuse left ventricular fibrosis defined by cardiac magnetic resonance: The PRIMERI Study
    Theingi Tiffany Win
    Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland Division of Cardiology, Department of Medicine, University of New Mexico, Albuquerque, New Mexico
    Heart Rhythm 12:155-62. 2015
    ..Abnormal P-terminal force in lead V1 (PTFV1) is associated with an increased risk of heart failure, stroke, atrial fibrillation, and death...
  23. pmc Global Electric Heterogeneity Risk Score for Prediction of Sudden Cardiac Death in the General Population: The Atherosclerosis Risk in Communities (ARIC) and Cardiovascular Health (CHS) Studies
    Jonathan W Waks
    From Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA J W W, A E B, M E J Cardiovascular Health Research Unit, Division of Cardiology, and Department of Epidemiology C M S, M L B, N S, D S S and Department of Biostatistics M L B, University of Washington, Seattle Epidemiological Cardiology Research Center, Division of Public Health Sciences and Department of Medicine, Cardiology Section, Wake Forest School of Medicine, Winston Salem, NC E Z S Knight Cardiovascular Institute, Oregon Health and Science University, Portland M K, E G, C A H, L G T Brigham and Women s Hospital, Harvard Medical School, Boston, MA T B S, S D S Department of Epidemiology, Internal Medicine and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins School of Public Health, Baltimore, MD S K A New York Academy of Medicine, New York D S S and Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD W S P, L G T
    Circulation 133:2222-34. 2016
    ..Asymptomatic individuals account for the majority of sudden cardiac deaths (SCDs). Development of effective, low-cost, and noninvasive SCD risk stratification tools is necessary...
  24. pmc Rationale and design for the Predictors of Arrhythmic and Cardiovascular Risk in End Stage Renal Disease (PACE) study
    Rulan S Parekh
    Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, USA
    BMC Nephrol 16:63. 2015
    ..Despite this high risk, surprisingly few prospective studies have studied clinical- and dialysis-related risk factors for sudden cardiac death and arrhythmic precursors of sudden cardiac death in end-stage renal disease...
  25. pmc Electromechanical relationship in hypertrophic cardiomyopathy
    Xiaoping Lin
    Division of Cardiology, Johns Hopkins University School of Medicine, 720 Rutland Ave, Ross 871, Baltimore, MD 21201, USA
    J Cardiovasc Transl Res 6:604-15. 2013
    ..LVH and repolarization abnormalities on surface EKG are markers of impaired systolic and diastolic mechanics in HCM. ..
  26. doi request reprint Lability of R- and T-wave peaks in three-dimensional electrocardiograms in implantable cardioverter defibrillator patients with ventricular tachyarrhythmia during follow-up
    Lichy Han
    Whiting School of Engineering, The Johns Hopkins University, Baltimore, MD 21287, USA
    J Electrocardiol 43:577-82. 2010
    ..We propose a novel method for the assessment of variability of both depolarization and repolarization phases of the cardiac cycle...
  27. pmc Electrocardiographic J Wave and Cardiovascular Outcomes in the General Population (from the Atherosclerosis Risk In Communities Study)
    Wesley T O'Neal
    Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia Electronic address
    Am J Cardiol 118:811-5. 2016
    ..74, 95% CI 0.43 to 1.25; P-interaction = 0.030). In conclusion, our findings suggest that the J wave is a benign entity that is not associated with an increased risk for sudden cardiac arrest in middle-aged adults in the United States. ..
  28. pmc Dynamic Changes in High-Sensitivity Cardiac Troponin I Are Associated with Dynamic Changes in Sum Absolute QRST Integral on Surface Electrocardiogram in Acute Decompensated Heart Failure
    Larisa G Tereshchenko
    The Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD, USA
    Ann Noninvasive Electrocardiol . 2016
    ..We hypothesized that there is an association between patient-specific changes in SAI QRST and myocardial injury as measured by high-sensitivity troponin I (hsTnI)...
  29. pmc Electrical Dyssynchrony on Noninvasive Electrocardiographic Mapping correlates with SAI QRST on surface ECG
    Larisa G Tereshchenko
    Oregon Health and Science University, Knight Cardiovascular Institute, Portland, OR, USA Johns Hopkins University School of Medicine, Cardiovascular Division, Baltimore, MD, USA
    Comput Cardiol (2010) 42:69-72. 2015
    ..The goal of this study was to compare associations between clinical and ECG predictors of cardiac resynchronization therapy (CRT) response with electrical dyssynchrony...
  30. pmc Beat-to-beat determinants of the beat-to-beat temporal and spatial variability of repolarization
    Albert Feeny
    Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA
    J Electrocardiol 49:417-22. 2016
    ..The goal of this study was to compare the time series predictors of beat-to-beat variability in repolarization in healthy individuals...
  31. doi request reprint A Patient Presents with Longstanding, Severe LV Dysfunction. Is There a Role for Additional Risk Stratification Before ICD?
    Larisa G Tereshchenko
    The Electrophysiology Chapter, Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Carnegie 568, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Card Electrophysiol Clin 4:151-60. 2012
    ..The authors discuss risk-stratification approaches in different patient populations with structural heart disease and systolic heart failure. ..
  32. pmc Novel measure of electrical dyssynchrony predicts response in cardiac resynchronization therapy: Results from the SMART-AV Trial
    Larisa G Tereshchenko
    Johns Hopkins University School of Medicine, Baltimore, Maryland Oregon Health and Science University, Knight Cardiovascular Institute, Portland, Oregon Electronic address
    Heart Rhythm 12:2402-10. 2015
    ..Cardiac resynchronization therapy (CRT) reduces mortality and morbidity in selected heart failure patients. However, not all patients respond to CRT...
  33. pmc Electrocardiographic deep terminal negativity of the P wave in V(1) and risk of sudden cardiac death: the Atherosclerosis Risk in Communities (ARIC) study
    Larisa G Tereshchenko
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD L G T, W S P Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR L G T, C A H
    J Am Heart Assoc 3:e001387. 2014
    ..We hypothesized that DTNPV1 is associated with increased risk of sudden cardiac death (SCD)...
  34. pmc Repolarization lability measured on 10-second ECG by spatial TT' angle: reproducibility and agreement with QT variability
    Albert Feeny
    Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA
    J Electrocardiol 47:708-15. 2014
    ..Reproducibility of spatial TT' angle on the 10-second ECG and its agreement with QT variability has not been previously studied...
  35. doi request reprint Evolutionary innovations in cardiac pacing
    Alan Cheng
    Department of Medicine, Division of Cardiology, Section of Cardiac Electrophysiology, Johns Hopkins Medical Institutes, Baltimore, MD, USA
    J Electrocardiol 44:611-5. 2011
    ..This article reviews the advances made and the future direction of innovations in cardiac pacing...