Affiliation: Johns Hopkins University
- Protein S-nitrosylation: role for nitric oxide signaling in neuronal deathNeelam Shahani
Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Biochim Biophys Acta 1820:736-42. 2012..In particular, an increasing number of studies have identified important roles for S-nitrosylation in regulating cell death...
- Nitric oxide signaling and nitrosative stress in neurons: role for S-nitrosylationNeelam Shahani
Department of Psychiatry, Johns Hopkins University School of Medicine, 600N Wolfe St, Baltimore, MD 21287, USA
Antioxid Redox Signal 14:1493-504. 2011..In this review, these molecular mechanisms, especially those in the central nervous system and neurodegenerative disorders, are described...
- Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesiaSrinivasa Subramaniam
The Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Nat Neurosci 15:191-3. 2012..Moreover, Rhes(-/-) mice showed reduced striatal mTOR signaling and diminished dyskinesia, but maintained motor improvement on L-DOPA treatment, suggesting a therapeutic benefit for Rhes-binding drugs...