Johannes Reisert

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc The Ca-activated Cl channel and its control in rat olfactory receptor neurons
    Johannes Reisert
    Institut für Biologische Informationsverarbeitung, Frorschungszentrum Jülich, 52425 Julich, Germany
    J Gen Physiol 122:349-63. 2003
  2. pmc Mechanism of the excitatory Cl- response in mouse olfactory receptor neurons
    Johannes Reisert
    Department of Neuroscience, Johns Hopkins School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205, USA
    Neuron 45:553-61. 2005
  3. pmc Olfactory marker protein modulates the cAMP kinetics of the odour-induced response in cilia of mouse olfactory receptor neurons
    Johannes Reisert
    Department of Neuroscience, Johns Hopkins University School of Medicine, 725 N Wolfe Street, Baltimore, MD 21205, USA
    J Physiol 585:731-40. 2007
  4. pmc ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification
    Aaron B Stephan
    Department of Biology, The Johns Hopkins University School of Medicine, Baltimore, MD 21218, USA
    Proc Natl Acad Sci U S A 106:11776-81. 2009
  5. pmc Olfactory CNG channel desensitization by Ca2+/CaM via the B1b subunit affects response termination but not sensitivity to recurring stimulation
    Yijun Song
    Department of Biology, The Johns Hopkins University, Baltimore, MD 21218, USA
    Neuron 58:374-86. 2008
  6. pmc The Na(+)/Ca(2+) exchanger NCKX4 governs termination and adaptation of the mammalian olfactory response
    Aaron B Stephan
    Department of Biology, The Johns Hopkins University, Baltimore, Maryland, USA
    Nat Neurosci 15:131-7. 2012
  7. pmc Signaling by olfactory receptor neurons near threshold
    Vikas Bhandawat
    Solomon H Snyder Department of Neuroscience and Center for Sensory Biology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 107:18682-7. 2010
  8. pmc Activation of olfactory cyclic-nucleotide gated channels revisited
    Johannes Reisert
    Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 20205, USA
    J Physiol 569:4-5. 2005
  9. ncbi request reprint Regulation of cyclic nucleotide-gated channels
    Jonathan Bradley
    Department of Neuroscience, Johns Hopkins School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA
    Curr Opin Neurobiol 15:343-9. 2005
  10. pmc Elementary response of olfactory receptor neurons to odorants
    Vikas Bhandawat
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Science 308:1931-4. 2005

Collaborators

Detail Information

Publications12

  1. pmc The Ca-activated Cl channel and its control in rat olfactory receptor neurons
    Johannes Reisert
    Institut für Biologische Informationsverarbeitung, Frorschungszentrum Jülich, 52425 Julich, Germany
    J Gen Physiol 122:349-63. 2003
    ..These densities, together with the Ca2+ diffusion coefficient, demonstrate that a given Cl channel is activated by Ca2+ originating from multiple CNG channels, thus allowing low-noise amplification of the olfactory receptor current...
  2. pmc Mechanism of the excitatory Cl- response in mouse olfactory receptor neurons
    Johannes Reisert
    Department of Neuroscience, Johns Hopkins School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205, USA
    Neuron 45:553-61. 2005
    ..Thus, a single functional architecture serves two entirely different purposes, probably underscoring the epithelial origin of the ORNs...
  3. pmc Olfactory marker protein modulates the cAMP kinetics of the odour-induced response in cilia of mouse olfactory receptor neurons
    Johannes Reisert
    Department of Neuroscience, Johns Hopkins University School of Medicine, 725 N Wolfe Street, Baltimore, MD 21205, USA
    J Physiol 585:731-40. 2007
    ..These observations also help explain the deficits in odour detection threshold and odour quality discrimination seen in the OMP(-/-) mice...
  4. pmc ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification
    Aaron B Stephan
    Department of Biology, The Johns Hopkins University School of Medicine, Baltimore, MD 21218, USA
    Proc Natl Acad Sci U S A 106:11776-81. 2009
    ..Considering these findings together, we propose that ANO2 constitutes the olfactory calcium-activated chloride channel...
  5. pmc Olfactory CNG channel desensitization by Ca2+/CaM via the B1b subunit affects response termination but not sensitivity to recurring stimulation
    Yijun Song
    Department of Biology, The Johns Hopkins University, Baltimore, MD 21218, USA
    Neuron 58:374-86. 2008
    ....
  6. pmc The Na(+)/Ca(2+) exchanger NCKX4 governs termination and adaptation of the mammalian olfactory response
    Aaron B Stephan
    Department of Biology, The Johns Hopkins University, Baltimore, Maryland, USA
    Nat Neurosci 15:131-7. 2012
    ..These results establish the role of NCKX4 in shaping olfactory responses and suggest that rapid response termination and proper adaptation of peripheral sensory receptor cells tune the sensory system for optimal perception...
  7. pmc Signaling by olfactory receptor neurons near threshold
    Vikas Bhandawat
    Solomon H Snyder Department of Neuroscience and Center for Sensory Biology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 107:18682-7. 2010
    ..2 pA. Thus, it takes about 35 odorant-binding events successfully triggering transduction during a brief odorant pulse in order for an ORN to signal to the brain...
  8. pmc Activation of olfactory cyclic-nucleotide gated channels revisited
    Johannes Reisert
    Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD 20205, USA
    J Physiol 569:4-5. 2005
  9. ncbi request reprint Regulation of cyclic nucleotide-gated channels
    Jonathan Bradley
    Department of Neuroscience, Johns Hopkins School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA
    Curr Opin Neurobiol 15:343-9. 2005
    ....
  10. pmc Elementary response of olfactory receptor neurons to odorants
    Vikas Bhandawat
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Science 308:1931-4. 2005
    ..Thus, signal amplification in olfactory transduction appears fundamentally different from that of phototransduction...
  11. ncbi request reprint Calcium, the two-faced messenger of olfactory transduction and adaptation
    Hugh R Matthews
    Physiological Laboratory, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK
    Curr Opin Neurobiol 13:469-75. 2003
    ..The feedback actions of Ca(2+) on different elements of the transduction cascade seem to occur on different timescales, and are therefore responsible for shaping different parts of the receptor current response to odour stimulation...
  12. pmc Loss of CNGB1 protein leads to olfactory dysfunction and subciliary cyclic nucleotide-gated channel trapping
    Stylianos Michalakis
    Department Pharmazie, Zentrum für Pharmaforschung, Ludwig Maximilians Universitüt München, D 81377 Munchen, Germany
    J Biol Chem 281:35156-66. 2006
    ..Second, together with the CNGA4 subunit, CNGB1 is needed for ciliary targeting of the olfactory CNG channel...