Affiliation: Johns Hopkins University
- Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome: Nothing New Under the SunNirupama Putcha
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, 5501 Hopkins Bayview Circle, JHAAC 4B 74, Baltimore, MD 21224, USA Electronic address
Immunol Allergy Clin North Am 36:515-28. 2016..Understanding the mechanisms underlying these subtypes will hopefully lead into a better understanding of therapeutic strategies that can target specific pathobiologic pathways. ..
- Indoor pollutant exposure is associated with heightened respiratory symptoms in atopic compared to non-atopic individuals with COPDDeepak A Kaji
Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
BMC Pulm Med 14:147. 2014..The aim of this study was to determine whether atopic individuals with COPD have greater susceptibility to PM compared to non-atopic individuals with COPD...
- Impact of co-morbidities on self-rated health in self-reported COPD: an analysis of NHANES 2001-2008Nirupama Putcha
Johns Hopkins School of Medicine, Department of Medicine, Division of Pulmonary and Critical Care Medicine, Baltimore, Maryland 21224, USA
COPD 10:324-32. 2013..CHF, arthritis, diabetes and incontinence/prostate disease have the most impact on self-rated health. Targeting these co-morbidities in COPD may result in improved self-rated health...
- Does prolonged β-lactam infusions improve clinical outcomes compared to intermittent infusions? A meta-analysis and systematic review of randomized, controlled trialsPranita D Tamma
Department of Pediatric Infectious Diseases, Johns Hopkins Medical Institutions, Baltimore, MD, USA
BMC Infect Dis 11:181. 2011..The primary objective of this meta-analysis was to determine if prolonged β-lactam infusion resulted in decreased mortality and improved clinical cure compared to intermittent β-lactam infusion...
- Comorbidities and Chronic Obstructive Pulmonary Disease: Prevalence, Influence on Outcomes, and ManagementNirupama Putcha
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland
Semin Respir Crit Care Med 36:575-91. 2015..In this article, we summarize existing knowledge about comorbidity burden and specific comorbidities in COPD, focusing on prevalence estimates, association with outcomes, and existing knowledge about treatment strategies. ..
- Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohortNirupama Putcha
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Thorax . 2016..Second-hand smoke (SHS) exposure has been linked to the development of and morbidity from lung disease. We sought to advance understanding of the impact of SHS on health-related outcomes in individuals with COPD...
- Obesity is Associated with Increased Morbidity in Moderate to Severe COPDAllison A Lambert
Department of Medicine Division of Pulmonary and Critical Care Johns Hopkins University, Baltimore, MD, USA Electronic address
Chest . 2016..Obesity is prevalent in the United States; however the impact of obesity upon COPD morbidity is unclear. We hypothesized that obesity is associated with worse outcomes in COPD...
- A simplified score to quantify comorbidity in COPDNirupama Putcha
Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
PLoS ONE 9:e114438. 2014..We sought to develop and validate a COPD-specific comorbidity score that reflects comorbidity burden on patient-centered outcomes...
- Chronic productive cough is associated with death in smokers with early COPDNirupama Putcha
1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
COPD 11:451-8. 2014..Respiratory causes of death are common among those with cough and phlegm. Such information can help to identify subsets of individuals with COPD having higher risk for adverse outcomes...
- Occupational exposures are associated with worse morbidity in patients with chronic obstructive pulmonary diseaseLaura M Paulin
1 Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
Am J Respir Crit Care Med 191:557-65. 2015..Links between occupational exposures and morbidity in individuals with established chronic obstructive pulmonary disease (COPD) remain unclear...