K W Pratz
Affiliation: Johns Hopkins University
- A pharmacodynamic study of sorafenib in patients with relapsed and refractory acute leukemiasK W Pratz
Division of Hematologic Malignancies, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA
Leukemia 24:1437-44. 2010..Although sorafenib showed only modest clinical activity as a single agent in this heavily treated population, robust inhibition of FLT3 and ERK suggests that there may be a potential important role in combination therapies...