Khurram Nasir

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Potential implications of coronary artery calcium testing for guiding aspirin use among asymptomatic individuals with diabetes
    Michael Gordon Silverman
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, Maryland, USA
    Diabetes Care 35:624-6. 2012
  2. doi request reprint Interplay of coronary artery calcification and traditional risk factors for the prediction of all-cause mortality in asymptomatic individuals
    Khurram Nasir
    Baptist Health South Florida, Miami, FL, USA
    Circ Cardiovasc Imaging 5:467-73. 2012
  3. doi request reprint Variation in atherosclerotic plaque composition according to increasing coronary artery calcium scores on computed tomography angiography
    Khurram Nasir
    Johns Hopkins Ciccarone Preventive Cardiology Center, Baltimore, Maryland, USA
    Int J Cardiovasc Imaging 26:923-32. 2010
  4. pmc Coronary artery calcium in relation to initiation and continuation of cardiovascular preventive medications: The Multi-Ethnic Study of Atherosclerosis (MESA)
    Khurram Nasir
    Ciccarone Preventive Cardiology Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Circ Cardiovasc Qual Outcomes 3:228-35. 2010
  5. doi request reprint Relationship of aortic valve calcification with coronary artery calcium severity: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Khurram Nasir
    Division of Cardiology, Blalock 524 C, Johns Hopkins University, 600N Wolfe Street, Baltimore, MD 21287, USA
    J Cardiovasc Comput Tomogr 4:41-6. 2010
  6. doi request reprint Noninvasive assessment of gender differences in coronary plaque composition with multidetector computed tomographic angiography
    Khurram Nasir
    Ciccarone Preventive Cardiology Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 105:453-8. 2010
  7. pmc Relationship of carotid distensibility and thoracic aorta calcification: multi-ethnic study of atherosclerosis
    Michael J Blaha
    Johns Hopkins Ciccarone Preventive Cardiology Center, Baltimore, MD, USA
    Hypertension 54:1408-15. 2009
  8. doi request reprint Gender differences in coronary plaque composition by coronary computed tomography angiography
    Michael J Blaha
    Johns Hopkins Ciccarone Preventive Cardiology Center, Baltimore, Maryland, USA
    Coron Artery Dis 20:506-12. 2009
  9. pmc Ethnic and sex differences in fatty liver on cardiac computed tomography: the multi-ethnic study of atherosclerosis
    Rajesh Tota-Maharaj
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, Md Department of Cardiology, Danbury Hospital, Danbury, CT
    Mayo Clin Proc 89:493-503. 2014
  10. doi request reprint Impact of coronary computed tomographic angiography results on patient and physician behavior in a low-risk population
    John W McEvoy
    Johns Hopkins Ciccarone Center for Prevention of Heart Disease, Baltimore, Maryland, USA
    Arch Intern Med 171:1260-8. 2011

Detail Information

Publications100

  1. pmc Potential implications of coronary artery calcium testing for guiding aspirin use among asymptomatic individuals with diabetes
    Michael Gordon Silverman
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, Maryland, USA
    Diabetes Care 35:624-6. 2012
    ..It is unclear whether coronary artery calcium (CAC) is effective for risk stratifying patients with diabetes in whom treatment decisions are uncertain...
  2. doi request reprint Interplay of coronary artery calcification and traditional risk factors for the prediction of all-cause mortality in asymptomatic individuals
    Khurram Nasir
    Baptist Health South Florida, Miami, FL, USA
    Circ Cardiovasc Imaging 5:467-73. 2012
    ..We sought to examine the relationship between the presence and burden of traditional RFs and CAC for the prediction of all-cause mortality...
  3. doi request reprint Variation in atherosclerotic plaque composition according to increasing coronary artery calcium scores on computed tomography angiography
    Khurram Nasir
    Johns Hopkins Ciccarone Preventive Cardiology Center, Baltimore, Maryland, USA
    Int J Cardiovasc Imaging 26:923-32. 2010
    ..A higher CACS is more likely to be associated with heterogeneous coronary plaque (combination of calcified, non-calcified, and mixed plaques), and appears to be more strongly associated with a higher burden of mixed plaque...
  4. pmc Coronary artery calcium in relation to initiation and continuation of cardiovascular preventive medications: The Multi-Ethnic Study of Atherosclerosis (MESA)
    Khurram Nasir
    Ciccarone Preventive Cardiology Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Circ Cardiovasc Qual Outcomes 3:228-35. 2010
    ....
  5. doi request reprint Relationship of aortic valve calcification with coronary artery calcium severity: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Khurram Nasir
    Division of Cardiology, Blalock 524 C, Johns Hopkins University, 600N Wolfe Street, Baltimore, MD 21287, USA
    J Cardiovasc Comput Tomogr 4:41-6. 2010
    ..Aortic valve calcification (AVC) and atherosclerosis share causative and pathologic features...
  6. doi request reprint Noninvasive assessment of gender differences in coronary plaque composition with multidetector computed tomographic angiography
    Khurram Nasir
    Ciccarone Preventive Cardiology Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 105:453-8. 2010
    ..Future studies are needed to elucidate whether these underlying differences in plaque composition might explain the reduced risk of cardiac events in women...
  7. pmc Relationship of carotid distensibility and thoracic aorta calcification: multi-ethnic study of atherosclerosis
    Michael J Blaha
    Johns Hopkins Ciccarone Preventive Cardiology Center, Baltimore, MD, USA
    Hypertension 54:1408-15. 2009
    ..The prognostic significance of these findings requires longitudinal follow-up of the Multi-Ethnic Study of Atherosclerosis cohort...
  8. doi request reprint Gender differences in coronary plaque composition by coronary computed tomography angiography
    Michael J Blaha
    Johns Hopkins Ciccarone Preventive Cardiology Center, Baltimore, Maryland, USA
    Coron Artery Dis 20:506-12. 2009
    ..Although males are thought to have a higher prevalence of atherosclerosis for a given age, there are currently few data regarding age-adjusted sex differences in plaque morphology and composition...
  9. pmc Ethnic and sex differences in fatty liver on cardiac computed tomography: the multi-ethnic study of atherosclerosis
    Rajesh Tota-Maharaj
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, Md Department of Cardiology, Danbury Hospital, Danbury, CT
    Mayo Clin Proc 89:493-503. 2014
    ..To describe ethnic and sex differences in the prevalence and determinants of fatty liver in a multiethnic cohort...
  10. doi request reprint Impact of coronary computed tomographic angiography results on patient and physician behavior in a low-risk population
    John W McEvoy
    Johns Hopkins Ciccarone Center for Prevention of Heart Disease, Baltimore, Maryland, USA
    Arch Intern Med 171:1260-8. 2011
    ..The impact of screening coronary computed tomographic angiography (CCTA) on physician and patient behavior is unclear...
  11. pmc Association between coronary artery calcification progression and microalbuminuria: the MESA study
    Andrew P DeFilippis
    Division of Cardiology, The Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins University, Baltimore, Maryland, USA
    JACC Cardiovasc Imaging 3:595-604. 2010
    ..This study sought to evaluate the relationship between microalbuminuria (MA) and the development and progression of atherosclerosis, as assessed by incident and progression of coronary artery calcification (CAC)...
  12. doi request reprint Mortality incidence and the severity of coronary atherosclerosis assessed by computed tomography angiography
    Matthew P Ostrom
    Division of Cardiology, Department of Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, California 90502, USA
    J Am Coll Cardiol 52:1335-43. 2008
    ..This study investigated whether cardiac computed tomography angiography (CTA) can predict all-cause mortality in symptomatic patients...
  13. pmc Associations between C-reactive protein, coronary artery calcium, and cardiovascular events: implications for the JUPITER population from MESA, a population-based cohort study
    Michael J Blaha
    Johns Hopkins Ciccarone Preventive Cardiology Center, Baltimore, MD 21287, USA
    Lancet 378:684-92. 2011
    ..In a population eligible for JUPITER, we established whether coronary artery calcium (CAC) might further stratify risk; additionally we compared hsCRP with CAC for risk prediction across the range of low and high hsCRP values...
  14. pmc Low-risk lifestyle, coronary calcium, cardiovascular events, and mortality: results from MESA
    Haitham M Ahmed
    Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins Hospital, 600 N Wolfe St, Baltimore, MD 21287, USA
    Am J Epidemiol 178:12-21. 2013
    ..In conclusion, a combination of regular exercise, healthy diet, smoking avoidance, and weight maintenance was associated with lower coronary calcium incidence, slower calcium progression, and lower all-cause mortality over 7.6 years. ..
  15. pmc Impact of fitness versus obesity on routinely measured cardiometabolic risk in young, healthy adults
    Michael N Vranian
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, USA
    Am J Cardiol 111:991-5. 2013
    ..These findings underscore the need for weight loss in obese patients and suggest an unmeasured benefit of fitness...
  16. doi request reprint Favorable cardiovascular risk factor profile is associated with reduced prevalence of coronary artery calcification and inflammation in asymptomatic nondiabetic white men
    Erin D Michos
    Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Prev Cardiol 11:189-94. 2008
    ..70; P<.001). Our study supports the notion that a favorable CVD profile is associated with less underlying atherosclerosis and inflammation and further highlights the importance of primary prevention of CVRFs...
  17. pmc Cardiovascular events with absent or minimal coronary calcification: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Matthew J Budoff
    Division of Cardiology, Los Angeles Biomedical Research Center, Torrance, CA 90502, USA
    Am Heart J 158:554-61. 2009
    ..In this study, we sought to evaluate the characteristics associated with incident CHD events in the setting of minimal (score <or=10) or absent CAC (score of zero)...
  18. pmc Association between obesity, high-sensitivity C-reactive protein ≥2 mg/L, and subclinical atherosclerosis: implications of JUPITER from the Multi-Ethnic Study of Atherosclerosis
    Michael J Blaha
    Johns Hopkins Ciccarone Preventive Cardiology Center, Baltimore, MD, USA
    Arterioscler Thromb Vasc Biol 31:1430-8. 2011
    ....
  19. pmc Relationship between common carotid intima-media thickness and thoracic aortic calcification: the Multi-Ethnic Study of Atherosclerosis
    Junichiro Takasu
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA 90502, USA
    Atherosclerosis 209:142-6. 2010
    ..No previous study has examined the relationship between CIMT and TAC in a large patient cohort. We performed a cross-sectional study to determine whether, at baseline, there is a relationship between CIMT and CT-determined TAC score...
  20. ncbi request reprint Association of body mass index, metabolic syndrome, and leukocyte count
    Milind Y Desai
    Ciccarone Preventive Cardiology Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 97:835-8. 2006
    ..29, p = 0.42) and groups 3 and 4 (coefficient 0.25, p = 0.41). The association between obesity and leukocyte count was highly dependent on the presence of MS...
  21. ncbi request reprint Regional differences in systolic and diastolic function in arrhythmogenic right ventricular dysplasia/cardiomyopathy using magnetic resonance imaging
    Chandra Bomma
    Division of Cardiology Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Am J Cardiol 95:1507-11. 2005
    ..In this study, we report results of quantitative evaluation of biventricular global and regional function using peak ejection rate and peak filling rate as measures of systolic and diastolic function, respectively (volumetric method)...
  22. pmc Progression of coronary calcium and incident coronary heart disease events: MESA (Multi-Ethnic Study of Atherosclerosis)
    Matthew J Budoff
    Division of Cardiology, LA Biomedical Research Institute, Harbor UCLA Medical Center, Los Angeles, California, USA
    J Am Coll Cardiol 61:1231-9. 2013
    ..The study examined whether progression of coronary artery calcium (CAC) is a predictor of future coronary heart disease (CHD) events...
  23. doi request reprint Impact of coronary artery calcification on all-cause mortality in individuals with and without hypertension
    Garth Graham
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, USA
    Atherosclerosis 225:432-7. 2012
    ..Coronary artery calcium (CAC) has emerged as an important prognostic indicator for coronary heart disease risk. The purpose of this study was to assess the impact of increasing CAC burden among those with and without hypertension (HTN)...
  24. pmc Relation of uric acid to serum levels of high-sensitivity C-reactive protein, triglycerides, and high-density lipoprotein cholesterol and to hepatic steatosis
    Tanya Keenan
    Johns Hopkins Ciccarone Preventive Cardiology Center, Baltimore, Maryland, USA
    Am J Cardiol 110:1787-92. 2012
    ..In conclusion, high UA levels were associated with increased TG/HDL and hepatic steatosis independently of metabolic syndrome and obesity and with increased hs-CRP independently of metabolic syndrome...
  25. ncbi request reprint Arterial stiffness is associated with regional ventricular systolic and diastolic dysfunction: the Multi-Ethnic Study of Atherosclerosis
    Verônica Rolim S Fernandes
    Division of Cardiology, Johns Hopkins University, Baltimore, MD 21287, USA
    Arterioscler Thromb Vasc Biol 28:194-201. 2008
    ..Few studies have investigated the relationship between arterial compliance and LV function in humans, and none used cardiovascular MRI...
  26. pmc The relationship of insulin resistance and extracoronary calcification in the multi-ethnic study of atherosclerosis
    Geoffrey H Tison
    Johns Hopkins Ciccarone Preventive Cardiology Center, Baltimore, MD 21287, USA
    Atherosclerosis 218:507-10. 2011
    ..We hypothesized that insulin resistance, measured by the homeostasis model assessment of insulin resistance (HOMA), is independently associated with prevalent and incident extra-coronary calcification (ECC)...
  27. pmc Coronary artery diameter related to calcium scores and coronary risk factors as measured with multidetector computed tomography: a substudy of the ACCURACY trial
    Yasmin S Hamirani
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, California 90502, USA
    Tex Heart Inst J 40:261-7. 2013
    ..These findings suggest a link between arterial remodeling and the severity of atherosclerosis...
  28. pmc Mortality rates in smokers and nonsmokers in the presence or absence of coronary artery calcification
    John W McEvoy
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, USA
    JACC Cardiovasc Imaging 5:1037-45. 2012
    ..The aim of this study was to further explore the interplay between smoking status, coronary artery calcium (CAC), and all-cause mortality...
  29. ncbi request reprint Diabetes and progression of coronary calcium under the influence of statin therapy
    Matthew J Budoff
    Division of Cardiology, Harbor UCLA Medical Center Research and Education Institute, Torrance, Calif 90502, USA
    Am Heart J 149:695-700. 2005
    ..We sought to evaluate the progression of atherosclerosis in asymptomatic persons with type 2 diabetes and measure the influence of statin therapy on CAC progression...
  30. ncbi request reprint Relation of family history of premature coronary heart disease and metabolic risk factors to risk of coronary arterial calcium in asymptomatic subjects
    Erin D Michos
    Ciccarone Preventative Cardiology Center, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 95:655-7. 2005
    ..Our study demonstrated that a familial propensity to subclinical atherosclerosis interacts with the presence of >/=2 metabolic RFs, magnifying the risks for those exposed to both...
  31. doi request reprint Relation of aortic valve calcium detected by cardiac computed tomography to all-cause mortality
    Michael J Blaha
    Ciccarone Preventive Cardiology Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 106:1787-91. 2010
    ..03) as well as traditional risk factors plus the presence of CAC (chi-square = 3.58, p = 0.05). In conclusion, AVC was associated with increased all-cause mortality, independent of the traditional risk factors and the presence of CAC...
  32. ncbi request reprint The metabolic syndrome adds incremental value to the Framingham risk score in identifying asymptomatic individuals with higher degrees of inflammation
    Catherine Y Campbell
    The Ciccarone Preventive Cardiology Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    J Cardiometab Syndr 3:7-11. 2008
    ..66; 95% CI, 1.39-5.07). The study findings suggest that MS adds value to the FRS in identifying those with higher degrees of inflammation, especially among those classified as low-risk by the FRS...
  33. ncbi request reprint Underlying risk factors incrementally add to the standard risk estimate in detecting subclinical atherosclerosis in low- and intermediate-risk middle-aged asymptomatic individuals
    Milind Y Desai
    Ciccarone Preventive Cardiology Center, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Am Heart J 148:871-7. 2004
    ..High burden of coronary artery calcification (CAC) on electron beam tomography (EBT) is a CHD risk equivalent...
  34. ncbi request reprint The association of subclinical coronary atherosclerosis with abdominal and total obesity in asymptomatic men
    Khurram Nasir
    The Ciccarone Preventive Cardiology Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Prev Cardiol 8:143-8. 2005
    ..Our results are consistent with evidence that measures of central obesity, compared with body mass index, are more strongly related to clinical as well as subclinical coronary heart disease end points...
  35. doi request reprint A synergistic relationship of elevated low-density lipoprotein cholesterol levels and systolic blood pressure with coronary artery calcification
    Kiran Musunuru
    The Ciccarone Preventive Cardiology Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Atherosclerosis 200:368-73. 2008
    ..038). The finding of an interaction between SBP and LDL-C relation to CAC in asymptomatic men support the response-to-injury model of atherogenesis...
  36. doi request reprint Relation between self-reported physical activity level, fitness, and cardiometabolic risk
    Camille Michael Minder
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, Maryland
    Am J Cardiol 113:637-43. 2014
    ..In conclusion, self-reported physical activity level and directly measured fitness are moderately correlated, and the latter is more strongly associated with a protective cardiovascular risk profile...
  37. pmc Association between resting heart rate and inflammatory biomarkers (high-sensitivity C-reactive protein, interleukin-6, and fibrinogen) (from the Multi-Ethnic Study of Atherosclerosis)
    Seamus P Whelton
    Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, Maryland Electronic address
    Am J Cardiol 113:644-9. 2014
    ..In conclusion, an increased HR at rest was associated with a higher level of inflammation among an ethnically diverse group of subjects without known cardiovascular disease...
  38. pmc Association of resting heart rate with carotid and aortic arterial stiffness: multi-ethnic study of atherosclerosis
    Seamus P Whelton
    Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Hypertension 62:477-84. 2013
    ....
  39. ncbi request reprint Ethnic differences of the presence and severity of coronary atherosclerosis
    Matthew J Budoff
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, 1124 W Carson Street, Bldg RB 2, Torrance, CA, USA
    Atherosclerosis 187:343-50. 2006
    ..The objective of the study is to assess the differences in the prevalence and severity of coronary artery calcification, as a measure of atherosclerosis, in these different ethnic groups...
  40. ncbi request reprint Coronary artery calcification and family history of premature coronary heart disease: sibling history is more strongly associated than parental history
    Khurram Nasir
    The Ciccarone Preventive Cardiology Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Circulation 110:2150-6. 2004
    ....
  41. doi request reprint Relationship of thoracic aortic calcium to coronary calcium and its progression (from the Multi-Ethnic Study of Atherosclerosis [MESA])
    Juan J Rivera
    Division of Cardiology, Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins Hospital, Baltimore, Maryland, USA
    Am J Cardiol 103:1562-7. 2009
    ..25 to 30.18). In conclusion, TAC is associated with the incidence and progression of CAC. The detection of TAC may improve risk stratification efforts. Future clinical outcomes studies are needed to support such an approach...
  42. ncbi request reprint Relationship of subclinical coronary atherosclerosis and National Cholesterol Education Panel guidelines in asymptomatic Brazilian men
    Khurram Nasir
    Ciccarone Preventive Cardiology Center, Blalock 524 C Cardiology, Johns Hopkins Hospital, 600 N Wolfe Street Baltimore, MD 21287, United States
    Int J Cardiol 108:68-75. 2006
    ....
  43. pmc Coronary calcium predicts events better with absolute calcium scores than age-sex-race/ethnicity percentiles: MESA (Multi-Ethnic Study of Atherosclerosis)
    Matthew J Budoff
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA 90502, USA
    J Am Coll Cardiol 53:345-52. 2009
    ..In this study, we aimed to establish whether age-sex-specific percentiles of coronary artery calcium (CAC) predict cardiovascular outcomes better than the actual (absolute) CAC score...
  44. ncbi request reprint Relationship between C-reactive protein levels and regional left ventricular function in asymptomatic individuals: the Multi-Ethnic Study of Atherosclerosis
    Boaz D Rosen
    Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Am Coll Cardiol 49:594-600. 2007
    ..This study sought to investigate the relationship between C-reactive protein (CRP) and regional left ventricular (LV) function in asymptomatic individuals without a history of cardiovascular disease...
  45. pmc Resting heart rate as predictor for left ventricular dysfunction and heart failure: MESA (Multi-Ethnic Study of Atherosclerosis)
    Anders Opdahl
    Cardiology Division, Johns Hopkins University, Baltimore, Maryland Department of Cardiology, Rikshospitalet, Oslo University Hospital and University of Oslo, Oslo, Norway
    J Am Coll Cardiol 63:1182-9. 2014
    ..The objective of this study was to investigate the relationship between baseline resting heart rate and incidence of heart failure (HF) and global and regional left ventricular (LV) dysfunction...
  46. doi request reprint Family history of coronary heart disease and markers of subclinical cardiovascular disease: where do we stand?
    Arvind K Pandey
    Department of Medicine, Johns Hopkins Hospital, Baltimore, MD, USA
    Atherosclerosis 228:285-94. 2013
    ....
  47. doi request reprint Gender differences in coronary plaque composition and burden detected in symptomatic patients referred for coronary computed tomographic angiography
    Waqas Qureshi
    Division of Cardiology, Department of Internal Medicine, Henry Ford Hospital Wayne State University, Detroit, MI, USA
    Int J Cardiovasc Imaging 29:463-9. 2013
    ..Future studies are needed to determine the prognostic implications of these findings...
  48. doi request reprint Association between high-sensitivity C-reactive protein and coronary plaque subtypes assessed by 64-slice coronary computed tomography angiography in an asymptomatic population
    Jonathan Rubin
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Circ Cardiovasc Imaging 4:201-9. 2011
    ..We sought to analyze the relationship between levels of CRP and coronary plaque subtypes as assessed by coronary computed tomography angiography...
  49. doi request reprint Coronary artery calcification and inflammation according to various metabolic syndrome definitions
    Venkata Narla
    Johns Hopkins University Ciccarone Preventive Cardiology Center, Baltimore, MD, USA
    J Cardiometab Syndr 4:33-9. 2009
    ..69 (95% CI, 1.04-2.73), 1.84 (95% CI, 1.14-2.95), and 1.66 (95% CI, 1.05-2.62), respectively. MS is associated with increased subclinical atherosclerosis and inflammation irrespective of various definitions...
  50. doi request reprint Association of traditional cardiovascular risk factors with coronary plaque sub-types assessed by 64-slice computed tomography angiography in a large cohort of asymptomatic subjects
    Juan J Rivera
    Johns Hopkins Ciccarone Preventive Cardiology Center, Baltimore, MD, USA
    Atherosclerosis 206:451-7. 2009
    ..In this study, we investigate the relationship between traditional CV risk factors and the presence and extent of coronary plaque sub-types in a large group of asymptomatic individuals...
  51. pmc Relationships of thoracic aortic wall calcification to cardiovascular risk factors: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Junichiro Takasu
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA 90502, USA
    Am Heart J 155:765-71. 2008
    ..We performed a cross-sectional study to determine which of these variables are independently associated with thoracic calcium...
  52. ncbi request reprint Framingham risk equation underestimates subclinical atherosclerosis risk in asymptomatic women
    Erin D Michos
    Ciccarone Preventive Cardiology Center, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Atherosclerosis 184:201-6. 2006
    ..However, the adequacy of FRE for identifying asymptomatic women with CAC is unknown...
  53. ncbi request reprint Combined effect of high low-density lipoprotein cholesterol and metabolic syndrome on subclinical coronary atherosclerosis in white men without clinical evidence of myocardial ischemia
    Catherine Y Campbell
    The Ciccarone Preventive Cardiology Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 100:840-3. 2007
    ..In conclusion, these results suggest that the risk of CAC in asymptomatic men with moderate or high LDL cholesterol is magnified in persons with MS...
  54. ncbi request reprint Predictors of recurrence following catheter ablation of atrial fibrillation using an irrigated-tip ablation catheter
    Chandrasekhar R Vasamreddy
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 0409, USA
    J Cardiovasc Electrophysiol 15:692-7. 2004
    ..The aims of this study were to identify predictors of recurrence after catheter ablation of atrial fibrillation (AF) and to report the safety and efficacy of catheter ablation of AF using an irrigated-tip ablation catheter...
  55. ncbi request reprint Arrhythmogenic right ventricular dysplasia: a United States experience
    Darshan Dalal
    Division of Cardiology, The Johns Hopins University School of Medicine, Baltimore, MD, USA
    Circulation 112:3823-32. 2005
    ..The purpose of our study was to describe the presentation, clinical features, survival, and natural history of ARVD in a large cohort of patients from the United States...
  56. ncbi request reprint Electrocardiographic findings over time in arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Jonathan P Piccini
    Division of Cardiology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Am J Cardiol 96:122-6. 2005
    ..Over a median of 43 months, 89% of the patients had evidence of progression, with S-wave prolongation being the most prevalent marker of ECG progression...
  57. doi request reprint High-sensitivity C-reactive protein and cardiovascular disease: a resolute belief or an elusive link?
    Omair Yousuf
    Johns Hopkins Ciccarone Center for Prevention of Heart Disease, Baltimore, Maryland 21287, USA
    J Am Coll Cardiol 62:397-408. 2013
    ..Furthermore, we highlight recommendations from societies and important considerations when using hsCRP to guide treatment decisions in the primary prevention setting...
  58. doi request reprint Absence of coronary artery calcification and all-cause mortality
    Michael Blaha
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD 21287, USA
    JACC Cardiovasc Imaging 2:692-700. 2009
    ..We sought to quantify the mortality rates associated with absent and low positive (CAC 1 to 10) coronary artery calcium (CAC)...
  59. pmc Impact of subclinical atherosclerosis on cardiovascular disease events in individuals with metabolic syndrome and diabetes: the multi-ethnic study of atherosclerosis
    Shaista Malik
    Heart Disease Prevention Program, Division of Cardiology, University of California Irvine, Irvine, California, USA
    Diabetes Care 34:2285-90. 2011
    ..We evaluated whether screening for coronary artery calcium (CAC) and carotid intimal-medial thickness (CIMT) can improve CVD risk stratification over traditional risk factors (RFs) in people with MetS and diabetes...
  60. pmc Hepatic steatosis, obesity, and the metabolic syndrome are independently and additively associated with increased systemic inflammation
    Chiadi E Ndumele
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, USA
    Arterioscler Thromb Vasc Biol 31:1927-32. 2011
    ..The goal of this study was to assess the independent and collective associations of hepatic steatosis, obesity, and the metabolic syndrome with elevated high-sensitivity C-reactive protein (hs-CRP) levels...
  61. pmc Thoracic aortic distensibility and thoracic aortic calcium (from the Multi-Ethnic Study of Atherosclerosis [MESA])
    Mouaz H Al-Mallah
    Division of Cardiology, Henry Ford Hospital, Wayne State University, Detroit, MI, USA
    Am J Cardiol 106:575-80. 2010
    ..In conclusion, our analysis has demonstrated that increased arterial stiffness is associated with increased TAC, independent of ethnicity and other atherosclerotic risk factors...
  62. ncbi request reprint Coronary calcium progression rates with a zero initial score by electron beam tomography
    Ambarish Gopal
    Division of Cardiology, Los Angeles Biomedical Research Center at Harbor UCLA, Torrance, CA, USA
    Int J Cardiol 117:227-31. 2007
    ..In this study, we sought to determine the rate of new calcifications in patients initially presenting with a zero initial score on electron beam tomography (EBT)...
  63. ncbi request reprint Findings on magnetic resonance imaging of idiopathic right ventricular outflow tachycardia
    Harikrishna Tandri
    Division of Cardiology, Department of Radiology, The Johns Hopkins University, Baltimore, Maryland, USA
    Am J Cardiol 94:1441-5. 2004
    ..There were no differences in incidence of qualitative MRI findings in patients compared with controls. These findings do not favor an association between anatomic abnormalities and arrhythmia in these patients...
  64. ncbi request reprint Magnetic resonance imaging of arrhythmogenic right ventricular dysplasia: sensitivity, specificity, and observer variability of fat detection versus functional analysis of the right ventricle
    Harikrishna Tandri
    Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    J Am Coll Cardiol 48:2277-84. 2006
    ....
  65. ncbi request reprint Electron beam tomography in women. Is it a valuable test?
    Khurram Nasir
    The Ciccarone Preventive Cardiology Center, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Cardiol Rev 13:174-83. 2005
    ..Finally, EBT has the potential to determine the consequences of therapeutic interventions regarding progression, stabilization, or regression of coronary atherosclerotic disease...
  66. ncbi request reprint Relation of degree of physical activity to coronary artery calcium score in asymptomatic individuals with multiple metabolic risk factors
    Milind Y Desai
    Ciccarone Preventive Cardiology Center, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Am J Cardiol 94:729-32. 2004
    ..Thus, asymptomatic patients who have > or =2 metabolic risk factors and who regularly engage in long-duration PA have a lower prevalence of CAC than do those who are sedentary or participate in moderate-duration PA...
  67. doi request reprint Detection of occult coronary artery disease in asymptomatic individuals with diabetes mellitus using non-invasive cardiac angiography
    Juan J Rivera
    Johns Hopkins Ciccarone Preventive Cardiology Center, Baltimore, MD, USA
    Atherosclerosis 203:442-8. 2009
    ....
  68. ncbi request reprint Noninvasive detection of myocardial fibrosis in arrhythmogenic right ventricular cardiomyopathy using delayed-enhancement magnetic resonance imaging
    Harikrishna Tandri
    Division of Cardiology, The Johns Hopkins University, Baltimore, MD 21287, USA
    J Am Coll Cardiol 45:98-103. 2005
    ..We evaluated the role of myocardial delayed-enhancement (MDE) magnetic resonance imaging (MRI) for noninvasive detection of fibrosis in Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C)...
  69. ncbi request reprint Clinical prediction of cavotricuspid isthmus dependence in patients referred for catheter ablation of "typical" atrial flutter
    Lars Lickfett
    Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Cardiovasc Electrophysiol 16:969-73. 2005
    ..The surface electrocardiogram (ECG) is not always diagnostic of isthmus dependence of AFL. The aim of this study was to evaluate clinical parameters for the prediction of isthmus-dependent AFL...
  70. pmc The association of Framingham and Reynolds risk scores with incidence and progression of coronary artery calcification in MESA (Multi-Ethnic Study of Atherosclerosis)
    Andrew P DeFilippis
    Division of Cardiology, University of Louisville, Rudd Heart and Lung Center, Louisville, Kentucky, USA
    J Am Coll Cardiol 58:2076-83. 2011
    ..The purpose of this study was to compare the association of the Framingham risk score (FRS) and Reynolds risk score (RRS) with subclinical atherosclerosis, assessed by incidence and progression of coronary artery calcium (CAC)...
  71. doi request reprint Utility of coronary artery calcium scoring in the evaluation of patients with chest pain
    Rajesh Tota-Maharaj
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Division of Cardiology, Baltimore, MD 21287, USA
    Crit Pathw Cardiol 11:99-106. 2012
    ..Although further research is needed, carefully selected ED patients with a normal electrocardiogram, normal cardiac biomarkers, and CAC = 0 may be considered for early discharge without further testing...
  72. ncbi request reprint Coronary artery calcium volume scores on electron beam tomography in 12,936 asymptomatic adults
    Khurram Nasir
    Ciccarone Preventive Cardiology Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Am J Cardiol 93:1146-9. 2004
    ..The 2 scores increased as the number of atherosclerotic risk factors increased. The volume scores were statistically smaller than the Agatston scores at the upper quartile level...
  73. ncbi request reprint Angiotensin-converting enzyme inhibitors and change in aortic valve calcium
    Kevin D O'Brien
    Division of Cardiology, Box 356422, Department of Medicine, University of Washington, 1959 NE Pacific St, Seattle, WA 98195, USA
    Arch Intern Med 165:858-62. 2005
    ....
  74. ncbi request reprint Visualizing coronary calcium is associated with improvements in adherence to statin therapy
    Nove K Kalia
    Division of Cardiology, Harbor UCLA Medical Center, Research and Education Institute, Torrance, CA, USA
    Atherosclerosis 185:394-9. 2006
    ..We evaluated whether visualization of coronary calcium would positively affect patients' adherence rates...
  75. ncbi request reprint Lower myocardial perfusion reserve is associated with decreased regional left ventricular function in asymptomatic participants of the multi-ethnic study of atherosclerosis
    Boaz D Rosen
    Cardiology Division, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
    Circulation 114:289-97. 2006
    ..Nevertheless, the relation between flow reserve and regional myocardial function has not been studied in individuals without a history of clinical heart disease...
  76. doi request reprint High prevalence of cardiometabolic risk factors in women considered low risk by traditional risk assessment
    Irene S Pollin
    Sister to Sister, Everyone Has a Heart Foundation, Bethesda, Maryland, USA
    J Womens Health (Larchmt) 17:947-53. 2008
    ....
  77. ncbi request reprint Evolving role of multidetector computed tomography in evaluation of arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Chandra Bomma
    Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 100:99-105. 2007
    ..Limitations include implantable cardioverter-defibrillators and motion artifacts, along with well-known radiation and contrast-induced reaction...
  78. doi request reprint Coronary artery calcium progression: an important clinical measurement? A review of published reports
    John W McEvoy
    Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, Maryland, USA
    J Am Coll Cardiol 56:1613-22. 2010
    ..First, standards of how CAC progression should be defined and assessed need to be developed. In addition, there remains a need for further studies analyzing the effect of other cardiac therapies on CAC progression and cardiac outcomes...
  79. doi request reprint Injury patterns in long-term refugee populations: a survey of Afghan refugees
    Adnan A Hyder
    Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    J Trauma 66:888-94. 2009
    ..The Afghan Refugee Injury Survey (ARIS) was undertaken to describe the epidemiology of injuries in the long-term Afghan refugee population residing in Pakistan in 2002...
  80. ncbi request reprint Arrhythmogenic right ventricular dysplasia: ex vivo and in vivo fat detection with black-blood MR imaging
    Ernesto Castillo
    Russell H Morgan Dept of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe Street, MRI 143 Nelson Basement, Baltimore, MD 21287, USA
    Radiology 232:38-48. 2004
    ....
  81. ncbi request reprint Electrocardiographic features of arrhythmogenic right ventricular dysplasia/cardiomyopathy according to disease severity: a need to broaden diagnostic criteria
    Khurram Nasir
    Department of Medicine, The Johns Hopkins University, Baltimore, MD, USA
    Circulation 110:1527-34. 2004
    ..The purpose of this study was to systematically study diagnostic and prognostic electrocardiographic (ECG) characteristics of arrhythmogenic right ventricle dysplasia/cardiomyopathy (ARVD/C)...
  82. ncbi request reprint Implantable cardioverter-defibrillators in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Ariel Roguin
    Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA
    J Am Coll Cardiol 43:1843-52. 2004
    ..The aim of this study was to assess the outcome of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) patients treated with an implantable cardioverter-defibrillator (ICD)...
  83. ncbi request reprint Normal reference values for the adult right ventricle by magnetic resonance imaging
    Harikrishna Tandri
    Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Cardiol 98:1660-4. 2006
    ..These values will be useful to differentiate RV health from diseases that result in abnormal RV structure and function...
  84. ncbi request reprint Plasma homocysteine predicts progression of atherosclerosis
    M Leila Rasouli
    Division of Cardiology, Harbor UCLA Medical Center Research and Education Institute, Torrance, CA 90502, USA
    Atherosclerosis 181:159-65. 2005
    ..8 mg/L) had a median yearly progression of 22%, compared to 21% for those with CRP value = 0.9-11 mg/L (p = ns). Presence of elevated HCY (>12 micromol/L) strongly and independently predicts progression of coronary plaque burden...
  85. ncbi request reprint Hypoxia-inducible factor 1alpha polymorphism and coronary collaterals in patients with ischemic heart disease
    Jon R Resar
    Division of Cardiology, The Johns Hopkins University School of Medicine, Blalock 524, 600 North Wolfe St, Baltimore, MD 21287, USA
    Chest 128:787-91. 2005
    ..Hypoxia inducible factor 1 (HIF-1), a transcriptional activator that functions as a master regulator of oxygen homeostasis, is one possible genetic factor that could play an important role in modulating collateral development...
  86. pmc The relationship between insulin resistance and incidence and progression of coronary artery calcification: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Michael J Blaha
    Johns Hopkins Ciccarone Preventive Cardiology Center, Baltimore, Maryland
    Diabetes Care 34:749-51. 2011
    ..We sought to determine whether insulin resistance predicts the incidence and progression of coronary artery calcification (CAC)...
  87. ncbi request reprint Relationship of monocyte count and peripheral arterial disease: results from the National Health and Nutrition Examination Survey 1999-2002
    Khurram Nasir
    Cardiology Division, Department of Medicine, Johns Hopkins University, Baltimore, MD 21287 0409, USA
    Arterioscler Thromb Vasc Biol 25:1966-71. 2005
    ....
  88. doi request reprint Effect of patient visualization of coronary calcium by electron beam computed tomography on changes in beneficial lifestyle behaviors
    Raza H Orakzai
    Division of Cardiology, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Am J Cardiol 101:999-1002. 2008
    ..In conclusion, in addition to risk stratification of asymptomatic individuals, determination of CAC may also improve utilization of ASA therapy and behavioral modification...
  89. ncbi request reprint Relation of plasma lipoprotein levels with low-grade inflammation in white men without clinical evidence of myocardial ischemia
    Juan J Rivera
    Johns Hopkins Ciccarone Preventive Cardiology Center, Baltimore, Maryland, USA
    Am J Cardiol 100:450-4. 2007
    ..04), which was not found for other lipid parameters. In conclusion, in our study, only plasma triglyceride level was independently associated with a higher WBC count...
  90. ncbi request reprint Regional left ventricular function in individuals with mild to moderate renal insufficiency: the Multi-Ethnic Study of Atherosclerosis
    Khurram Nasir
    Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
    Am Heart J 153:545-51. 2007
    ..In this study we investigate the relationship between mild-moderate renal insufficiency and regional left ventricle function in a population free of cardiovascular disease...
  91. ncbi request reprint Late systolic onset of regional LV relaxation demonstrated in three-dimensional space by MRI tissue tagging
    Boaz D Rosen
    Cardiology Division, Blalock 524, Johns Hopkins Hospital, 600 N Wolfe Street, Baltimore, MD 21287 6568, USA
    Am J Physiol Heart Circ Physiol 287:H1740-6. 2004
    ..This unfolding pattern precedes longitudinal and circumferential elongation and may facilitate early diastolic filling...
  92. ncbi request reprint Elevated homocysteine is associated with reduced regional left ventricular function: the Multi-Ethnic Study of Atherosclerosis
    Khurram Nasir
    Division of Cardiology, Johns Hopkins University, Baltimore, MD, USA
    Circulation 115:180-7. 2007
    ..In this study, we aim to investigate the relationship between Hcy levels and regional left ventricular function in an asymptomatic population...
  93. ncbi request reprint Utility of stress testing and coronary calcification measurement for detection of coronary artery disease in women
    Khurram Nasir
    Divisions of Cardiology, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Arch Intern Med 164:1610-20. 2004
    ..For high-risk symptomatic women, a more aggressive approach involving coronary angiography appears to be the preferred initial diagnostic strategy...
  94. ncbi request reprint Misdiagnosis of arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Chandra Bomma
    Department of Cardiology Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Cardiovasc Electrophysiol 15:300-6. 2004
    ..Diagnosis is based on a set of criteria proposed by the International Task Force for Cardiomyopathies. We report our experience in providing a re-evaluation for patients who previously have been diagnosed with ARVD/C...
  95. ncbi request reprint Injuries among Afghan refugees: review of evidence
    Khurram Nasir
    Johns Hopkins Hospital, Baltimore, Maryland, USA
    Prehosp Disaster Med 19:169-73. 2004
    ....
  96. ncbi request reprint Magnetic resonance imaging findings in patients meeting task force criteria for arrhythmogenic right ventricular dysplasia
    Harikrishna Tandri
    Division of Cardiology, The Johns Hopkins University, Baltimore, Maryland, USA
    J Cardiovasc Electrophysiol 14:476-82. 2003
    ..We report qualitative and quantitative MRI findings in ARVD using state-of-the-art MRI...
  97. pmc Exposure to low-dose ionizing radiation from medical imaging procedures
    Reza Fazel
    Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30306, USA
    N Engl J Med 361:849-57. 2009
    ..The growing use of imaging procedures in the United States has raised concerns about exposure to low-dose ionizing radiation in the general population...
  98. ncbi request reprint Hypertension and smoking are associated with reduced regional left ventricular function in asymptomatic: individuals the Multi-Ethnic Study of Atherosclerosis
    Boaz D Rosen
    Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Am Coll Cardiol 47:1150-8. 2006
    ..This study sought to test the hypothesis that reduced regional left ventricular (LV) function is associated with traditional risk factors including hypertension, hypercholesterolemia, and smoking in asymptomatic individuals...
  99. ncbi request reprint Subclinical atherosclerosis and incipient regional myocardial dysfunction in asymptomatic individuals: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Veronica R S Fernandes
    Division of Cardiology, Johns Hopkins University, Baltimore, Maryland, USA
    J Am Coll Cardiol 47:2420-8. 2006
    ..This study sought to determine whether increased carotid intima-media thickness (IMT) is related to reduced regional myocardial function in participants of the Multi-Ethnic Study of Atherosclerosis (MESA)...
  100. ncbi request reprint Electron beam CT versus helical CT scans for assessing coronary calcification: current utility and future directions
    Khurram Nasir
    Division of Cardiology, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Am Heart J 146:969-77. 2003
    ..Traditional risk factors for coronary artery disease predict the development of atherosclerosis; however, their ability to identify individual patients at risk of events is limited...