ANDREW L MAMMEN

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Autoantibodies against 3-hydroxy-3-methylglutaryl-coenzyme A reductase in patients with statin-associated autoimmune myopathy
    ANDREW L MAMMEN
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Arthritis Rheum 63:713-21. 2011
  2. pmc Increased frequency of DRB1*11:01 in anti-hydroxymethylglutaryl-coenzyme A reductase-associated autoimmune myopathy
    ANDREW L MAMMEN
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Arthritis Care Res (Hoboken) 64:1233-7. 2012
  3. pmc Expression of the dermatomyositis autoantigen Mi-2 in regenerating muscle
    ANDREW L MAMMEN
    Johns Hopkins Bayview, Johns Hopkins Myositis Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
    Arthritis Rheum 60:3784-93. 2009
  4. pmc Rarity of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase antibodies in statin users, including those with self-limited musculoskeletal side effects
    ANDREW L MAMMEN
    Johns Hopkins University, Baltimore, Maryland, USA
    Arthritis Care Res (Hoboken) 64:269-72. 2012
  5. doi request reprint Autoimmune myopathies: autoantibodies, phenotypes and pathogenesis
    ANDREW L MAMMEN
    Department of Neurology, Johns Hopkins Bayview Medical Center, Johns Hopkins Myositis Center, Mason F Lord Building Center Tower, Suite 4500, Baltimore, MD 21224, USA USA
    Nat Rev Neurol 7:343-54. 2011
  6. doi request reprint Dermatomyositis and polymyositis: Clinical presentation, autoantibodies, and pathogenesis
    ANDREW L MAMMEN
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Ann N Y Acad Sci 1184:134-53. 2010
  7. pmc Antibody levels correlate with creatine kinase levels and strength in anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase-associated autoimmune myopathy
    Jessie L Werner
    Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    Arthritis Rheum 64:4087-93. 2012
  8. pmc A novel autoantibody recognizing 200-kd and 100-kd proteins is associated with an immune-mediated necrotizing myopathy
    Lisa Christopher-Stine
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Arthritis Rheum 62:2757-66. 2010
  9. pmc Isolated elevation of aldolase in the serum of myositis patients: a potential biomarker of damaged early regenerating muscle cells
    Livia Casciola-Rosen
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Clin Exp Rheumatol 30:548-53. 2012
  10. pmc Myositis autoantibodies
    Livia Casciola-Rosen
    Department of Medicine, Johns Hopkins University, School of Medicine, Baltimore, Maryland 21224, USA
    Curr Opin Rheumatol 24:602-8. 2012

Collaborators

Detail Information

Publications30

  1. pmc Autoantibodies against 3-hydroxy-3-methylglutaryl-coenzyme A reductase in patients with statin-associated autoimmune myopathy
    ANDREW L MAMMEN
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Arthritis Rheum 63:713-21. 2011
    ..The purpose of this study was to identify these molecules to help clarify the disease mechanism and facilitate diagnosis...
  2. pmc Increased frequency of DRB1*11:01 in anti-hydroxymethylglutaryl-coenzyme A reductase-associated autoimmune myopathy
    ANDREW L MAMMEN
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Arthritis Care Res (Hoboken) 64:1233-7. 2012
    ..To investigate the association of anti-hydroxymethylglutaryl-coenzyme A reductase (anti-HMGCR) myopathy with HLA class I and II antigens...
  3. pmc Expression of the dermatomyositis autoantigen Mi-2 in regenerating muscle
    ANDREW L MAMMEN
    Johns Hopkins Bayview, Johns Hopkins Myositis Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
    Arthritis Rheum 60:3784-93. 2009
    ..This study was undertaken to define the population of cells expressing high levels of Mi-2 in DM muscle and to explore the regulation and functional role of Mi-2 during muscle regeneration...
  4. pmc Rarity of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase antibodies in statin users, including those with self-limited musculoskeletal side effects
    ANDREW L MAMMEN
    Johns Hopkins University, Baltimore, Maryland, USA
    Arthritis Care Res (Hoboken) 64:269-72. 2012
    ..The current work assessed the prevalence of anti-HMGCR antibodies in these groups of statin users...
  5. doi request reprint Autoimmune myopathies: autoantibodies, phenotypes and pathogenesis
    ANDREW L MAMMEN
    Department of Neurology, Johns Hopkins Bayview Medical Center, Johns Hopkins Myositis Center, Mason F Lord Building Center Tower, Suite 4500, Baltimore, MD 21224, USA USA
    Nat Rev Neurol 7:343-54. 2011
    ..The contribution of interferon signaling to the development of dermatomyositis and the potential link between malignancies and the initiation of autoimmune myopathies are also assessed...
  6. doi request reprint Dermatomyositis and polymyositis: Clinical presentation, autoantibodies, and pathogenesis
    ANDREW L MAMMEN
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Ann N Y Acad Sci 1184:134-53. 2010
    ....
  7. pmc Antibody levels correlate with creatine kinase levels and strength in anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase-associated autoimmune myopathy
    Jessie L Werner
    Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    Arthritis Rheum 64:4087-93. 2012
    ..The main objective of this study was to define the association of anti-HMGCR antibody levels with disease activity...
  8. pmc A novel autoantibody recognizing 200-kd and 100-kd proteins is associated with an immune-mediated necrotizing myopathy
    Lisa Christopher-Stine
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Arthritis Rheum 62:2757-66. 2010
    ..The aim of this study was to identify novel autoantibodies in patients with necrotizing myopathy...
  9. pmc Isolated elevation of aldolase in the serum of myositis patients: a potential biomarker of damaged early regenerating muscle cells
    Livia Casciola-Rosen
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Clin Exp Rheumatol 30:548-53. 2012
    ..Elevated serum aldolase A levels occur in the absence of elevated creatine kinase M (CK) levels in a subset of myositis patients. This study was undertaken to investigate the cell biology of this unexplained clinical observation...
  10. pmc Myositis autoantibodies
    Livia Casciola-Rosen
    Department of Medicine, Johns Hopkins University, School of Medicine, Baltimore, Maryland 21224, USA
    Curr Opin Rheumatol 24:602-8. 2012
    ..To review recent advances in our understanding of autoantibodies associated with dermatomyositis and the autoimmune necrotizing myopathies...
  11. doi request reprint Dermatomyositis Patients with Anti-Nuclear Matrix Protein-2 Autoantibodies Have More Edema, More Severe Muscle Disease, and Increased Malignancy Risk
    Jemima Albayda
    Johns Hopkins University School of Medicine, Baltimore, MD
    Arthritis Care Res (Hoboken) . 2017
    ..The aim of this study was to characterize clinical features associated with anti-NXP-2 autoantibodies...
  12. doi request reprint More severe disease and slower recovery in younger patients with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase-associated autoimmune myopathy
    Eleni Tiniakou
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore
    Rheumatology (Oxford) . 2017
    ..To study disease severity and response to therapy in a large cohort of patients with anti-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR)-associated myositis...
  13. doi request reprint The spectrum of statin myopathy
    Payam Mohassel
    aDepartment of Neurology bDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Curr Opin Rheumatol 25:747-52. 2013
    ..The clinical characteristics of these patients, pathologic findings, associated autoantibody and immunogenetic risk factors are discussed...
  14. doi request reprint Thigh muscle MRI in immune-mediated necrotising myopathy: extensive oedema, early muscle damage and role of anti-SRP autoantibodies as a marker of severity
    Iago Pinal-Fernández
    National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA
    Ann Rheum Dis . 2016
    ....
  15. doi request reprint Assessment of Mortality in Autoimmune Myositis With and Without Associated Interstitial Lung Disease
    Cheilonda Johnson
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, 1830 E Monument Street Suite 500, Baltimore, MD, 21224, USA
    Lung 194:733-7. 2016
    ..Recent data on survival in idiopathic inflammatory myopathies originate primarily in Asia and Europe and vary widely. We sought to examine mortality in a large U.S. myositis cohort focusing in particular on the impact of associated ILD...
  16. doi request reprint Symptomatic and Electrodiagnostic Features of Peripheral Neuropathy in Scleroderma
    Julie J Paik
    Johns Hopkins University School of Medicine, Baltimore, Maryland
    Arthritis Care Res (Hoboken) 68:1150-7. 2016
    ..To determine the prevalence of peripheral neuropathy in scleroderma...
  17. pmc Spectrum of Muscle Histopathologic Findings in Forty-Two Scleroderma Patients With Weakness
    Julie J Paik
    Johns Hopkins University School of Medicine, Baltimore, Maryland
    Arthritis Care Res (Hoboken) 67:1416-25. 2015
    ..To determine if distinct muscle pathologic features exist in scleroderma subjects with weakness...
  18. pmc Cytosolic 5'-Nucleotidase 1A As a Target of Circulating Autoantibodies in Autoimmune Diseases
    Thomas E Lloyd
    Johns Hopkins University School of Medicine, Baltimore, Maryland
    Arthritis Care Res (Hoboken) 68:66-71. 2016
    ..This study was undertaken to define the prevalence and clinical features of anti-NT5C1A-positive patients with DM, PM, IBM, or other systemic autoimmune diseases...
  19. pmc Expression of the dermatomyositis autoantigen transcription intermediary factor 1γ in regenerating muscle
    Payam Mohassel
    Johns Hopkins University School of Medicine, Baltimore, Maryland
    Arthritis Rheumatol 67:266-72. 2015
    ..This study was undertaken to explore the regulation and functional role of this protein during muscle differentiation and regeneration...
  20. doi request reprint Statin-associated autoimmune myopathy and anti-HMGCR autoantibodies
    Payam Mohassel
    Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Muscle Nerve 48:477-83. 2013
    ....
  21. doi request reprint Magnetic resonance imaging of inflammatory myopathies
    Filippo Del Grande
    Russell H Morgan Department of Radiology and Radiological Science, School of Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA
    Top Magn Reson Imaging 22:39-43. 2011
    ..Lastly, we provide an overview about some advanced MRI techniques that focus more on function than on morphology of muscle...
  22. pmc The composition of cellular infiltrates in anti-HMG-CoA reductase-associated myopathy
    Tae Chung
    Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Muscle Nerve 52:189-95. 2015
    ..To characterize cellular infiltrates in muscle biopsies from patients with anti-3-hydroxy-3-methyl-gulatryl-CoA reductase (HMGCR)-associated myopathy...
  23. pmc A novel conserved isoform of the ubiquitin ligase UFD2a/UBE4B is expressed exclusively in mature striated muscle cells
    ANDREW L MAMMEN
    Johns Hopkins University School of Medicine, Department of Medicine, Division of Rheumatology, Baltimore, Maryland, United States of America
    PLoS ONE 6:e28861. 2011
    ..We conclude that the regulated expression of these UFD2a isoforms most likely imparts divergent functions that are important for myogenisis...
  24. pmc Expanding the spectrum of monoclonal light chain deposition disease in muscle
    Lyle W Ostrow
    Department of Neurology, Johns Hopkins School of Medicine, 733 N Broadway, Baltimore, Maryland 21205, USA
    Muscle Nerve 45:755-61. 2012
    ..The diagnosis of amyloid myopathy is delayed when monoclonal gammopathies are not detected on initial testing and muscle biopsies are nondiagnostic, and the EMG and symptoms can mimic an inflammatory myopathy...
  25. doi request reprint Statin myopathy: a review of recent progress
    ANDREW L MAMMEN
    Department of Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
    Curr Opin Rheumatol 22:644-50. 2010
    ..However, they can have myotoxic effects ranging in severity from myalgias to rhabdomyolysis. This review focuses on recent progress in defining the clinical features and mechanism(s) of statin-induced myopathy...
  26. doi request reprint Idiopathic Inflammatory Myopathies and Malignancy: a Comprehensive Review
    Eleni Tiniakou
    Division of Rheumatology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
    Clin Rev Allergy Immunol 52:20-33. 2017
    ..Indeed, patients with certain MSAs seem to be at particularly increased risk of malignancy. This review attempts a systematic evaluation of research regarding the association between malignancy and myositis...
  27. doi request reprint Spectrum of immune-mediated necrotizing myopathies and their treatments
    Iago Pinal-Fernández
    aNational Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda bJohns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Curr Opin Rheumatol 28:619-24. 2016
    ..This review aims to describe the spectrum of clinical, histological, and serological features in patients with immune-mediated necrotizing myopathies (IMNMs)...
  28. doi request reprint Longitudinal Assessment of Small Fiber Neuropathy: Evidence of a Non-Length-Dependent Distal Axonopathy
    Mohammad A Khoshnoodi
    Department of Neurology, Johns Hopkins University, Baltimore, Maryland
    JAMA Neurol 73:684-90. 2016
    ..Peripheral neuropathy typically follows a length-dependent pattern, leading us to hypothesize that patients with SFN would lose intraepidermal nerve fibers at the distal leg more quickly than at more proximal thigh sites...
  29. pmc Brief report: antisynthetase syndrome-associated myocarditis
    Kavita Sharma
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland Electronic address
    J Card Fail 20:939-45. 2014
    ..We describe 2 patients with AS syndrome who also developed myocarditis, depressed biventricular function, and congestive heart failure...
  30. pmc The co-existence of myasthenia gravis in patients with myositis: a case series
    Julie J Paik
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
    Semin Arthritis Rheum 43:792-6. 2014
    ..We reviewed the cases of 6 patients with both myositis and MG to identify clinical features that suggest the possibility of co-existing MG in myositis patients...