Igal Madar

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint Assessment of severity of coronary artery stenosis in a canine model using the PET agent 18F-fluorobenzyl triphenyl phosphonium: comparison with 99mTc-tetrofosmin
    Igal Madar
    Division of Nuclear Medicine, The Russell H Morgan Department of Radiology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Nucl Med 48:1021-30. 2007
  2. ncbi request reprint Characterization of membrane potential-dependent uptake of the novel PET tracer 18F-fluorobenzyl triphenylphosphonium cation
    Igal Madar
    Division of Nuclear Medicine, The Russell H Morgan Department of Radiology, The Johns Hopkins Medical Institutions, 601 N Caroline Street, Baltimore, MD 21287, USA
    Eur J Nucl Med Mol Imaging 34:2057-65. 2007
  3. pmc 18F-fluorobenzyl triphenyl phosphonium: a noninvasive sensor of brown adipose tissue thermogenesis
    Igal Madar
    Division of Nuclear Medicine, Russell H Morgan Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Nucl Med 52:808-14. 2011
  4. doi request reprint Detection and quantification of the evolution dynamics of apoptosis using the PET voltage sensor 18F-fluorobenzyl triphenyl phosphonium
    Igal Madar
    Russell H Morgan Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    J Nucl Med 50:774-80. 2009
  5. ncbi request reprint Imaging delta- and mu-opioid receptors by PET in lung carcinoma patients
    Igal Madar
    Department of Radiology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Nucl Med 48:207-13. 2007
  6. ncbi request reprint Characterization of uptake of the new PET imaging compound 18F-fluorobenzyl triphenyl phosphonium in dog myocardium
    Igal Madar
    Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Nucl Med 47:1359-66. 2006
  7. ncbi request reprint PET imaging of opioid receptors in pain: progress and new directions
    Hayden T Ravert
    Department of Radiology and Radiological Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Curr Pharm Des 10:759-68. 2004
  8. ncbi request reprint Quantification of brain mu-opioid receptors with [11C]carfentanil: reference-tissue methods
    Christopher J Endres
    Department of Radiology, Johns Hopkins University, Baltimore, MD 21287, USA
    Nucl Med Biol 30:177-86. 2003
  9. doi request reprint Stable delineation of the ischemic area by the PET perfusion tracer 18F-fluorobenzyl triphenyl phosphonium after transient coronary occlusion
    Takahiro Higuchi
    Division of Nuclear Medicine, Russell H Morgan Department of Radiology, Johns Hopkins University, Baltimore, Maryland, USA
    J Nucl Med 52:965-9. 2011
  10. doi request reprint Compensation for spill-in and spill-out partial volume effects in cardiac PET imaging
    Yong Du
    The Russell H Morgan Department of Radiology and Radiological Sciences, School of Medicine, Johns Hopkins University, 601 N Caroline St, JHOC 4263, Baltimore, MD 21287, USA
    J Nucl Cardiol 20:84-98. 2013

Detail Information

Publications12

  1. ncbi request reprint Assessment of severity of coronary artery stenosis in a canine model using the PET agent 18F-fluorobenzyl triphenyl phosphonium: comparison with 99mTc-tetrofosmin
    Igal Madar
    Division of Nuclear Medicine, The Russell H Morgan Department of Radiology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Nucl Med 48:1021-30. 2007
    ....
  2. ncbi request reprint Characterization of membrane potential-dependent uptake of the novel PET tracer 18F-fluorobenzyl triphenylphosphonium cation
    Igal Madar
    Division of Nuclear Medicine, The Russell H Morgan Department of Radiology, The Johns Hopkins Medical Institutions, 601 N Caroline Street, Baltimore, MD 21287, USA
    Eur J Nucl Med Mol Imaging 34:2057-65. 2007
    ....
  3. pmc 18F-fluorobenzyl triphenyl phosphonium: a noninvasive sensor of brown adipose tissue thermogenesis
    Igal Madar
    Division of Nuclear Medicine, Russell H Morgan Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Nucl Med 52:808-14. 2011
    ..We investigated an approach to detect BAT depots and monitor thermogenesis using the mitochondria-targeting voltage sensor radiolabeled fluorobenzyltriphenyl phosphonium (FBnTP)...
  4. doi request reprint Detection and quantification of the evolution dynamics of apoptosis using the PET voltage sensor 18F-fluorobenzyl triphenyl phosphonium
    Igal Madar
    Russell H Morgan Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    J Nucl Med 50:774-80. 2009
    ..Here, we have characterized the ability of the novel PET voltage sensor (18)F-fluorobenzyl triphenyl phosphonium ((18)F-FBnTP) to quantify the time-dependent apoptotic action of the taxanes paclitaxel and docetaxel in vitro and in vivo...
  5. ncbi request reprint Imaging delta- and mu-opioid receptors by PET in lung carcinoma patients
    Igal Madar
    Department of Radiology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Nucl Med 48:207-13. 2007
    ....
  6. ncbi request reprint Characterization of uptake of the new PET imaging compound 18F-fluorobenzyl triphenyl phosphonium in dog myocardium
    Igal Madar
    Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Nucl Med 47:1359-66. 2006
    ..Here, we characterize the 18F-FBnTP uptake and retention kinetics, in vitro and in vivo, as well as the myocardial and whole-body biodistribution in healthy dogs, using PET...
  7. ncbi request reprint PET imaging of opioid receptors in pain: progress and new directions
    Hayden T Ravert
    Department of Radiology and Radiological Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Curr Pharm Des 10:759-68. 2004
    ..The implication of this approach to the study of pain and pain syndromes, and possible clinical applications, is also addressed...
  8. ncbi request reprint Quantification of brain mu-opioid receptors with [11C]carfentanil: reference-tissue methods
    Christopher J Endres
    Department of Radiology, Johns Hopkins University, Baltimore, MD 21287, USA
    Nucl Med Biol 30:177-86. 2003
    ..It was determined that both a graphical method, and a simplified reference tissue model, were more accurate than the tissue-ratio method for quantification of CFN binding...
  9. doi request reprint Stable delineation of the ischemic area by the PET perfusion tracer 18F-fluorobenzyl triphenyl phosphonium after transient coronary occlusion
    Takahiro Higuchi
    Division of Nuclear Medicine, Russell H Morgan Department of Radiology, Johns Hopkins University, Baltimore, Maryland, USA
    J Nucl Med 52:965-9. 2011
    ..We used a rat model of transient coronary occlusion to determine the stability of the perfusion defect size over time and the magnitude of redistribution...
  10. doi request reprint Compensation for spill-in and spill-out partial volume effects in cardiac PET imaging
    Yong Du
    The Russell H Morgan Department of Radiology and Radiological Sciences, School of Medicine, Johns Hopkins University, 601 N Caroline St, JHOC 4263, Baltimore, MD 21287, USA
    J Nucl Cardiol 20:84-98. 2013
    ..It is important to compensate for both effects to achieve accurate quantification. In this study, an image-based partial volume compensation (PVC) method was developed and validated for cardiac PET...
  11. pmc Brown Adipose Tissue Response Dynamics: In Vivo Insights with the Voltage Sensor 18F-Fluorobenzyl Triphenyl Phosphonium
    Igal Madar
    Division of Nuclear Medicine, The Russell H Morgan Department of Radiology, The Johns Hopkins Medical Institutions, Baltimore, MD, United States of America
    PLoS ONE 10:e0129627. 2015
    ....
  12. ncbi request reprint Preferential accumulation of (3)H-tetraphenylphosphonium in non-small cell lung carcinoma in mice: comparison with (99m)Tc-MIBI
    Igal Madar
    Department of Medical Biophysics and Nuclear Medicine, Hadassah University Medical Center, Jerusalem, Israel
    J Nucl Med 43:234-8. 2002
    ..Here, we extend our studies of phosphonium cations to nonbrain tumors and characterize the biodistribution and tumor specificity of (3)H-tetraphenylphosphonium ((3)H-TPP) in non-small cell lung carcinoma in mice...