M Li

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi Use of a modified bacteriophage to probe the interactions between peptides and ion channel receptors in mammalian cells
    M Li
    Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Nat Biotechnol 15:559-63. 1997
  2. ncbi Accessory protein facilitated CFTR-CFTR interaction, a molecular mechanism to potentiate the chloride channel activity
    S Wang
    Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Cell 103:169-79. 2000
  3. ncbi Functional domains and expression of truncated atrial natriuretic peptide receptor-A: the carboxyl-terminal regions direct the receptor internalization and sequestration in COS-7 cells
    K N Pandey
    Department of Physiology, Tulane University School of Medicine, New Orleans, Louisiana, USA
    Mol Pharmacol 57:259-67. 2000
  4. ncbi The PDZ-interacting domain of cystic fibrosis transmembrane conductance regulator is required for functional expression in the apical plasma membrane
    B D Moyer
    Dartmouth Medical School, Department of Physiology, Hanover, New Hampshire 03755, USA
    J Biol Chem 275:27069-74. 2000
  5. ncbi The human delta1261 mutation of the HERG potassium channel results in a truncated protein that contains a subunit interaction domain and decreases the channel expression
    X Li
    Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Biol Chem 272:705-8. 1997
  6. pmc Activation by Ca2+/calmodulin of an exogenous myosin light chain kinase in mouse arteries
    H Raina
    Department of Physiology, School of Medicine, University of Maryland, Baltimore, MD 21201, USA
    J Physiol 587:2599-612. 2009
  7. ncbi In vitro selection of peptides acting at a new site of NMDA glutamate receptors
    M Li
    Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Nat Biotechnol 14:986-91. 1996
  8. ncbi Applications of display technology in protein analysis
    M Li
    Department of Physiology and Department of Neuroscience, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA
    Nat Biotechnol 18:1251-6. 2000
  9. ncbi Natriuretic peptide receptor-A negatively regulates mitogen-activated protein kinase and proliferation of mesangial cells: role of cGMP-dependent protein kinase
    K N Pandey
    Department of Physiology, Tulane University School of Medicine, New Orleans, Louisiana, 70112, USA
    Biochem Biophys Res Commun 271:374-9. 2000
  10. ncbi WAP-TAg transgenic mice and the study of dysregulated cell survival, proliferation, and mutation during breast carcinogenesis
    M Li
    The Institute of Human Virology, Division of Infectious Diseases, Department of Medicine, University of Maryland Medical School and the Baltimore Veterans Affairs Medical Center, Baltimore, Maryland, MD 21201, USA
    Oncogene 19:1010-9. 2000

Collaborators

Detail Information

Publications18

  1. ncbi Use of a modified bacteriophage to probe the interactions between peptides and ion channel receptors in mammalian cells
    M Li
    Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Nat Biotechnol 15:559-63. 1997
    ..This dual heterologous expression system offers a powerful approach to the molecular studies of protein-protein interactions...
  2. ncbi Accessory protein facilitated CFTR-CFTR interaction, a molecular mechanism to potentiate the chloride channel activity
    S Wang
    Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Cell 103:169-79. 2000
    ..Thus, the CFTR channel can be switched to a more active conducting state via a modification of intermolecular CFTR-CFTR contact that is enhanced by an accessory protein...
  3. ncbi Functional domains and expression of truncated atrial natriuretic peptide receptor-A: the carboxyl-terminal regions direct the receptor internalization and sequestration in COS-7 cells
    K N Pandey
    Department of Physiology, Tulane University School of Medicine, New Orleans, Louisiana, USA
    Mol Pharmacol 57:259-67. 2000
    ....
  4. ncbi The PDZ-interacting domain of cystic fibrosis transmembrane conductance regulator is required for functional expression in the apical plasma membrane
    B D Moyer
    Dartmouth Medical School, Department of Physiology, Hanover, New Hampshire 03755, USA
    J Biol Chem 275:27069-74. 2000
    ..Mutations that delete the C terminus of CFTR may cause cystic fibrosis because CFTR is not polarized, complexed with EBP50, or efficiently expressed in the apical membrane of epithelial cells...
  5. ncbi The human delta1261 mutation of the HERG potassium channel results in a truncated protein that contains a subunit interaction domain and decreases the channel expression
    X Li
    Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Biol Chem 272:705-8. 1997
    ..Such a decrease of potassium channel expression can contribute to the longer QT intervals observed in the patients with the HERG mutation...
  6. pmc Activation by Ca2+/calmodulin of an exogenous myosin light chain kinase in mouse arteries
    H Raina
    Department of Physiology, School of Medicine, University of Maryland, Baltimore, MD 21201, USA
    J Physiol 587:2599-612. 2009
    ..Forskolin mediated increases in cAMP, but not receptor mediated increases in cAMP cause a rapid decrease in the affinity of MLCK for Ca(2+)/CaM...
  7. ncbi In vitro selection of peptides acting at a new site of NMDA glutamate receptors
    M Li
    Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Nat Biotechnol 14:986-91. 1996
    ..Using biochemical binding analysis and patch clamp electrophysiological recording, we show that the synthetic Mag-1 peptides cause noncompetitive inhibition of the receptor channel activity...
  8. ncbi Applications of display technology in protein analysis
    M Li
    Department of Physiology and Department of Neuroscience, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA
    Nat Biotechnol 18:1251-6. 2000
    ..Several practical and theoretical challenges remain to be addressed before display technology can be readily applied to proteomic studies...
  9. ncbi Natriuretic peptide receptor-A negatively regulates mitogen-activated protein kinase and proliferation of mesangial cells: role of cGMP-dependent protein kinase
    K N Pandey
    Department of Physiology, Tulane University School of Medicine, New Orleans, Louisiana, 70112, USA
    Biochem Biophys Res Commun 271:374-9. 2000
    ..These results demonstrate that ANP/NPRA system negatively regulates MAPK/ERK2 activity and proliferation of mesangial cells in a PKG-dependent manner...
  10. ncbi WAP-TAg transgenic mice and the study of dysregulated cell survival, proliferation, and mutation during breast carcinogenesis
    M Li
    The Institute of Human Virology, Division of Infectious Diseases, Department of Medicine, University of Maryland Medical School and the Baltimore Veterans Affairs Medical Center, Baltimore, Maryland, MD 21201, USA
    Oncogene 19:1010-9. 2000
    ..The WAP-TAg model can be utilized to investigate how the basic processes of cell proliferation, apoptosis, DNA mutation, and DNA repair are modified by external and internal signals during mammary oncogenesis...
  11. ncbi Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex
    K Jo
    Department of Physiology, School of Medicine, University of California at San Francisco, San Francisco, California 94143 0444, USA
    J Neurosci 19:4189-99. 1999
    ..This work suggests a role for MALS proteins in regulating recruitment of neurotransmitter receptors to the PSD...
  12. ncbi A common mechanism for cystic fibrosis transmembrane conductance regulator protein activation by genistein and benzimidazolone analogs
    L Al-Nakkash
    Department of Physiology, Dalton Cardiovascular Research Center, University of Missouri, Columbia, Missouri 65211, USA
    J Pharmacol Exp Ther 296:464-72. 2001
    ..These studies should pave the way toward understanding the agonist binding sites at a molecular level...
  13. ncbi Applications of display technologies to proteomic analyses
    D Ma
    Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Cell Biochem Suppl . 2001
    ..Recent advances in protein display technologies and their applications to proteomic analyses have been discussed...
  14. ncbi Molecular studies of CFTR interacting proteins
    S Wang
    Department of Physiology, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA
    Pflugers Arch 443:S62-4. 2001
    ..Molecular understanding of these proteins may provide important insights into CFTR function in cystic fibrosis...
  15. pmc Differential effects of a saturated and a monounsaturated fatty acid on MHC class I antigen presentation
    S R Shaikh
    Department of Biology, Johns Hopkins University, 3400 North Charles Street, Mudd Hall Room 45, Baltimore, MD 21218, USA
    Scand J Immunol 68:30-42. 2008
    ....
  16. ncbi Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR)
    S Wang
    Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    FEBS Lett 427:103-8. 1998
    ..The specific and tight association suggests a potential regulatory role of NHE-RF in cystic fibrosis transmembrane conductance regulator (CFTR) function...
  17. ncbi A simplified method to prepare PCR template DNA for screening of transgenic and knockout mice
    S Ren
    Institute of Human Virology, Division of Infectious Diseases, Department of Medicine and the University of Maryland Medical School, Baltimore, Maryland 21201, USA
    Contemp Top Lab Anim Sci 40:27-30. 2001
    ..In addition, using ear instead of tail tissue can reduce distress of animals because the samples can be obtained when the mice are labeled by ear punch...
  18. ncbi Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2
    J Gong
    Department of Physiology, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA
    Science 285:1565-9. 1999
    ..Finally, ZIP1 and ZIP2 coexist in the same cell type and are elevated differentially by neurotrophic factors. These results provide a mechanism for specificity and regulation of PKCzeta-targeted phosphorylation...