Annette M Jackson

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint The problem of transplanting the sensitized patient: whose problem is it?
    Annette M Jackson
    Immunogenetics Laboratory, Johns Hopkins University School of Medicine, 2041 E Monument Street, Baltimore, MD 21205 2222, USA
    Front Biosci 13:1396-412. 2008
  2. doi request reprint Immunogenetics and immunology in transplantation
    Andrea A Zachary
    Immunogenetics Laboratory, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Immunol Res 47:232-9. 2010
  3. doi request reprint Transplanting the highly sensitized patient: trials and tribulations
    Hariharan S Iyer
    aDivision of Nephrology and Transplantation, Department of Medicine, London Health Sciences Center, The University of Western Ontario, London, Ontario, Canada bDepartment of Medicine cDepartment of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Curr Opin Nephrol Hypertens 22:681-8. 2013
  4. pmc Endothelial cell antibodies associated with novel targets and increased rejection
    Annette M Jackson
    Departments of Medicine
    J Am Soc Nephrol 26:1161-71. 2015
  5. doi request reprint A GPS for finding the route to transplantation for the sensitized patient
    Annette M Jackson
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Curr Opin Organ Transplant 17:433-9. 2012
  6. doi request reprint Multiple hyperacute rejections in the absence of detectable complement activation in a patient with endothelial cell reactive antibody
    A M Jackson
    Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA
    Am J Transplant 12:1643-9. 2012
  7. doi request reprint Clinical relevance and IgG subclass determination of non-HLA antibodies identified using endothelial cell precursors isolated from donor blood
    Annette M Jackson
    Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    Transplantation 92:54-60. 2011
  8. doi request reprint Using donor exchange paradigms with desensitization to enhance transplant rates among highly sensitized patients
    Robert A Montgomery
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Curr Opin Organ Transplant 16:439-43. 2011
  9. doi request reprint A flow cytometric crossmatch test using endothelial precursor cells isolated from peripheral blood
    Annette M Jackson
    Immunogenetics Laboratory, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Methods Mol Biol 1034:319-29. 2013
  10. pmc Podocyte effacement closely links to suPAR levels at time of posttransplantation focal segmental glomerulosclerosis occurrence and improves with therapy
    Nada Alachkar
    1 Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 2 Department of Medicine, Rush University Medical Center, Chicago, IL 3 Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 4 Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 5 Department of Surgery, University of Miami Miller School of Medicine, Miami, FL 6 Department of Medicine, Union Memorial Hospital, Baltimore, MD 7 Address correspondence to Nada Alachkar, M D, Department of Medicine, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross 971, Baltimore, MD 21205 and Jochen Reiser, M D, Ph D, Department of Medicine, Rush University Medical Center, Cohn Research Building, Suite 724, 1735 W Harrison Street, Chicago, IL 60612
    Transplantation 96:649-56. 2013

Collaborators

Detail Information

Publications13

  1. ncbi request reprint The problem of transplanting the sensitized patient: whose problem is it?
    Annette M Jackson
    Immunogenetics Laboratory, Johns Hopkins University School of Medicine, 2041 E Monument Street, Baltimore, MD 21205 2222, USA
    Front Biosci 13:1396-412. 2008
    ..Thus, sensitization to HLA antigens is a problem for the patient, the transplant physician, and the histocompatibility laboratory...
  2. doi request reprint Immunogenetics and immunology in transplantation
    Andrea A Zachary
    Immunogenetics Laboratory, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Immunol Res 47:232-9. 2010
    ..Ongoing studies are investigating the mechanisms underlying the down-regulation of donor HLA-specific antibodies...
  3. doi request reprint Transplanting the highly sensitized patient: trials and tribulations
    Hariharan S Iyer
    aDivision of Nephrology and Transplantation, Department of Medicine, London Health Sciences Center, The University of Western Ontario, London, Ontario, Canada bDepartment of Medicine cDepartment of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Curr Opin Nephrol Hypertens 22:681-8. 2013
    ..The number of highly sensitized patients on the renal transplant waiting list continues to increase. This review focuses on the options available to these patients and speculates on future directions for incompatible transplantation...
  4. pmc Endothelial cell antibodies associated with novel targets and increased rejection
    Annette M Jackson
    Departments of Medicine
    J Am Soc Nephrol 26:1161-71. 2015
    ..Given the growing number of transplant candidates, a better understanding of the antigenic targets, beyond HLA, and mechanisms of immune injury will be essential for improving long-term allograft survival. ..
  5. doi request reprint A GPS for finding the route to transplantation for the sensitized patient
    Annette M Jackson
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Curr Opin Organ Transplant 17:433-9. 2012
    ..Use of these protocols has revealed various factors that influence which route is the most likely to work for a given patient...
  6. doi request reprint Multiple hyperacute rejections in the absence of detectable complement activation in a patient with endothelial cell reactive antibody
    A M Jackson
    Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA
    Am J Transplant 12:1643-9. 2012
    ..Cultured splenocytes produced antibodies that bound donor ECs but not lymphocytes. Bortezomib was initiated on POD5. Despite aggressive therapy, the allograft never regained function...
  7. doi request reprint Clinical relevance and IgG subclass determination of non-HLA antibodies identified using endothelial cell precursors isolated from donor blood
    Annette M Jackson
    Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    Transplantation 92:54-60. 2011
    ..We investigated the relationship between AECAs identified using donor-derived endothelial cell precursors (ECPs) and kidney allograft rejection and function...
  8. doi request reprint Using donor exchange paradigms with desensitization to enhance transplant rates among highly sensitized patients
    Robert A Montgomery
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Curr Opin Organ Transplant 16:439-43. 2011
    ..The options for these patients include: remaining on the deceased-donor list, entering a kidney-paired donation scheme, or undergoing desensitization with high-dose IVIg or plasmapheresis and low-dose IVIg...
  9. doi request reprint A flow cytometric crossmatch test using endothelial precursor cells isolated from peripheral blood
    Annette M Jackson
    Immunogenetics Laboratory, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Methods Mol Biol 1034:319-29. 2013
    ..Isolation of endothelial precursor cells (EPCs) from peripheral blood now allows testing for antibodies reactive with non-HLA endothelial cell antigens...
  10. pmc Podocyte effacement closely links to suPAR levels at time of posttransplantation focal segmental glomerulosclerosis occurrence and improves with therapy
    Nada Alachkar
    1 Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 2 Department of Medicine, Rush University Medical Center, Chicago, IL 3 Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 4 Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 5 Department of Surgery, University of Miami Miller School of Medicine, Miami, FL 6 Department of Medicine, Union Memorial Hospital, Baltimore, MD 7 Address correspondence to Nada Alachkar, M D, Department of Medicine, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross 971, Baltimore, MD 21205 and Jochen Reiser, M D, Ph D, Department of Medicine, Rush University Medical Center, Cohn Research Building, Suite 724, 1735 W Harrison Street, Chicago, IL 60612
    Transplantation 96:649-56. 2013
    ..Serum soluble urokinase-type plasminogen activator receptor (suPAR) is implicated in the pathogenesis of native and recurrent FSGS...
  11. doi request reprint Impact of pronase on flow cytometric crossmatch outcome
    Sarah J Hetrick
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Hum Immunol 72:330-6. 2011
    ..Treatment with 1 mg/mL of pronase significantly increased reactivity in 20 of 23 tests of T cells (87%, p = 6.0 × 10(-5)). These data indicate that pronase treatment may result in erroneous FCXM results...
  12. doi request reprint Variable HLA expression on deceased donor lymphocytes: Not all crossmatches are created equal
    Jessica L Badders
    Department of Medicine, The Johns Hopkins University, Baltimore, MD 21205, USA
    Hum Immunol 76:795-800. 2015
    ..HLA expression is impacted by multiple factors and should be routinely monitored to ensure crossmatch sensitivity and to reconcile crossmatch strength with solid phase HLA antibody analyses...
  13. pmc A closer look at rituximab induction on HLA antibody rebound following HLA-incompatible kidney transplantation
    Annette M Jackson
    Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    Kidney Int 87:409-16. 2015
    ....