R F Gottesman

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc The ARIC-PET amyloid imaging study: Brain amyloid differences by age, race, sex, and APOE
    Rebecca F Gottesman
    From the Department of Neurology R F G, A L C S, Department of Radiology, Section of High Resolution Brain PET Imaging Y Z, X C, A R, D F W, and Departments of Psychiatry D F W and Neuroscience D F W, Johns Hopkins University School of Medicine Departments of Epidemiology R F G, A L C S, A R S and Environmental Health Sciences D F W, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD Departments of Radiology E G and Medicine T H M, University of Mississippi Medical Center, Jackson Hagerstown Imaging N G, MD Department of Neurology D S K, Mayo Clinic, Rochester, MN and Department of Radiology A M and Division of Public Health Sciences L E W, Wake Forest School of Medicine, Winston Salem, NC
    Neurology 87:473-80. 2016
  2. pmc Brain Aging in African-Americans: The Atherosclerosis Risk in Communities (ARIC) Experience
    Rebecca F Gottesman
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Curr Alzheimer Res 12:607-13. 2015
  3. pmc Chronic apraxia of speech and Broca's area
    Lydia A Trupe
    Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA
    Stroke 44:740-4. 2013
  4. pmc Patterns of regional cerebral blood flow associated with low hemoglobin in the Baltimore Longitudinal Study of Aging
    Rebecca F Gottesman
    Department of Neurology, Johns Hopkins University School of Medicine, Meyer 6 113, 600 North Wolfe Street, Baltimore, MD 21287, USA
    J Gerontol A Biol Sci Med Sci 67:963-9. 2012
  5. pmc Blood pressure and white-matter disease progression in a biethnic cohort: Atherosclerosis Risk in Communities (ARIC) study
    Rebecca F Gottesman
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Stroke 41:3-8. 2010
  6. pmc Neglect is more common and severe at extreme hemoglobin levels in right hemispheric stroke
    Rebecca F Gottesman
    Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Stroke 41:1641-5. 2010
  7. pmc Association between hypotension, low ejection fraction and cognitive performance in cardiac patients
    Rebecca F Gottesman
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Behav Neurol 22:63-71. 2010
  8. pmc The NIHSS-plus: improving cognitive assessment with the NIHSS
    Rebecca F Gottesman
    Johns Hopkins University School of Medicine, Department of Neurology, Baltimore, MD, USA
    Behav Neurol 22:11-5. 2010
  9. pmc Delirium after coronary artery bypass graft surgery and late mortality
    Rebecca F Gottesman
    Department of Neurology, Johns Hopkins University, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Ann Neurol 67:338-44. 2010
  10. pmc Hemostatic factors and subclinical brain infarction in a community-based sample: the ARIC study
    R F Gottesman
    Department of Neurology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Cerebrovasc Dis 28:589-94. 2009

Detail Information

Publications34

  1. pmc The ARIC-PET amyloid imaging study: Brain amyloid differences by age, race, sex, and APOE
    Rebecca F Gottesman
    From the Department of Neurology R F G, A L C S, Department of Radiology, Section of High Resolution Brain PET Imaging Y Z, X C, A R, D F W, and Departments of Psychiatry D F W and Neuroscience D F W, Johns Hopkins University School of Medicine Departments of Epidemiology R F G, A L C S, A R S and Environmental Health Sciences D F W, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD Departments of Radiology E G and Medicine T H M, University of Mississippi Medical Center, Jackson Hagerstown Imaging N G, MD Department of Neurology D S K, Mayo Clinic, Rochester, MN and Department of Radiology A M and Division of Public Health Sciences L E W, Wake Forest School of Medicine, Winston Salem, NC
    Neurology 87:473-80. 2016
    ..To evaluate differences in amyloid deposition in a community-based cohort without dementia by age, sex, race, education, and APOE ε4 allele status...
  2. pmc Brain Aging in African-Americans: The Atherosclerosis Risk in Communities (ARIC) Experience
    Rebecca F Gottesman
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Curr Alzheimer Res 12:607-13. 2015
    ..In addition, we will review some of the disparities by race in studies focusing on the genetics of stroke, small vessel disease, and dementia. ..
  3. pmc Chronic apraxia of speech and Broca's area
    Lydia A Trupe
    Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA
    Stroke 44:740-4. 2013
    ..Method- We tested 34 participants with chronic left supratentorial stroke on an AOS battery and obtained concurrent magnetic resonance imaging. We evaluated associations between AOS and locations and volume of infarct...
  4. pmc Patterns of regional cerebral blood flow associated with low hemoglobin in the Baltimore Longitudinal Study of Aging
    Rebecca F Gottesman
    Department of Neurology, Johns Hopkins University School of Medicine, Meyer 6 113, 600 North Wolfe Street, Baltimore, MD 21287, USA
    J Gerontol A Biol Sci Med Sci 67:963-9. 2012
    ..We investigated whether lower hemoglobin is associated with regional increases in relative CBF in older individuals, and if these increases occur in watershed regions...
  5. pmc Blood pressure and white-matter disease progression in a biethnic cohort: Atherosclerosis Risk in Communities (ARIC) study
    Rebecca F Gottesman
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Stroke 41:3-8. 2010
    ..We hypothesized that WMH progression would be (1) strongly related to BP in blacks and whites and (2) predicted more strongly by earlier (midlife) or cumulative BP measurements than by measures at older ages...
  6. pmc Neglect is more common and severe at extreme hemoglobin levels in right hemispheric stroke
    Rebecca F Gottesman
    Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Stroke 41:1641-5. 2010
    ..Anemia is 1 potential mechanism by which the brain receives inadequate oxygenation. The purpose of this study was to determine in acute stroke patients whether lower hemoglobin values were associated with worse hemispatial neglect...
  7. pmc Association between hypotension, low ejection fraction and cognitive performance in cardiac patients
    Rebecca F Gottesman
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Behav Neurol 22:63-71. 2010
    ..The purpose of this study was to determine if cardiac ejection fraction (EF) is associated with cognitive performance, and whether this is modified by low blood pressure...
  8. pmc The NIHSS-plus: improving cognitive assessment with the NIHSS
    Rebecca F Gottesman
    Johns Hopkins University School of Medicine, Department of Neurology, Baltimore, MD, USA
    Behav Neurol 22:11-5. 2010
    ..Patients may therefore receive a low NIHSS score despite a fairly large stroke. A broader scale including simple cognitive tests would improve the clinical and research utility of the NIHSS...
  9. pmc Delirium after coronary artery bypass graft surgery and late mortality
    Rebecca F Gottesman
    Department of Neurology, Johns Hopkins University, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Ann Neurol 67:338-44. 2010
    ..The primary goal of this study was to determine whether patients with delirium after coronary artery bypass graft (CABG) surgery have higher long-term out-of-hospital mortality when compared with CABG patients without delirium...
  10. pmc Hemostatic factors and subclinical brain infarction in a community-based sample: the ARIC study
    R F Gottesman
    Department of Neurology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Cerebrovasc Dis 28:589-94. 2009
    ..We evaluated the association between hemostatic factor levels and subclinical lacunar infarcts in a nested sample from a subset of the Atherosclerosis Risk in Communities (ARIC) cohort...
  11. doi request reprint Neurological complications of cardiac surgery
    Rebecca F Gottesman
    Department of Neurology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Semin Neurol 28:703-15. 2008
    ..Management of postoperative medications and early use of rehabilitation services is a recommended strategy to optimize the recovery for individuals with neurological injury after cardiac surgery...
  12. pmc Unilateral neglect is more severe and common in older patients with right hemispheric stroke
    R F Gottesman
    Department of Neurology, Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD 21287, USA
    Neurology 71:1439-44. 2008
    ..We studied patients with right hemispheric stroke to determine whether increasing age was associated with more frequent or more severe neglect...
  13. ncbi request reprint Early postoperative cognitive dysfunction and blood pressure during coronary artery bypass graft operation
    Rebecca F Gottesman
    Department of Neurology, Johns Hopkins University School of Medicine, Phipps 126, 600 N Wolfe St, Baltimore, MD 21287, USA
    Arch Neurol 64:1111-4. 2007
    ..To determine the relationship between change in blood pressure during coronary artery bypass graft operations and early cognitive dysfunction...
  14. pmc Vitamin D, vitamin D binding protein gene polymorphisms, race and risk of incident stroke: the Atherosclerosis Risk in Communities (ARIC) study
    A L C Schneider
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Eur J Neurol 22:1220-7. 2015
    ..It was hypothesized that associations of low 25(OH)D with stroke risk would be stronger amongst persons with genotypes associated with higher DBP levels...
  15. doi request reprint Site of the ischemic penumbra as a predictor of potential for recovery of functions
    A E Hillis
    Department of Neurology, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Meyer 6 113, 600 N Wolfe St, Baltimore, MD 21287, USA
    Neurology 71:184-9. 2008
    ..We tested the hypothesis that the presence of diffusion-perfusion mismatch within left BA 37 predicts probability and extent of short-term improvement of naming...
  16. pmc Action versus animal naming fluency in subcortical dementia, frontal dementias, and Alzheimer's disease
    C Davis
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Neurocase 16:259-66. 2010
    ....
  17. pmc Gender differences in unilateral spatial neglect within 24 hours of ischemic stroke
    Jonathan T Kleinman
    Department of Neurology, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Brain Cogn 68:49-52. 2008
    ..Multiple spatial neglect tasks were used to increase the sensitivity of neglect detection. No differences based upon gender were observed for the prevalence, severity, or a combined task measure of USN...
  18. pmc Hemorrhagic transformation in patients with acute ischaemic stroke and an indication for anticoagulation
    E B Marsh
    Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Eur J Neurol 20:962-7. 2013
    ..Anticoagulation theoretically increases risk. We evaluated stroke patients with an indication for anticoagulation to determine the factors associated with hemorrhagic transformation...
  19. doi request reprint Local intraarterial fibrinolysis administered in aliquots for the treatment of central retinal artery occlusion: the Johns Hopkins Hospital experience
    Eric M Aldrich
    Department of Neurology, Meyer 6 109, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Stroke 39:1746-50. 2008
    ..The aim is to compare the visual outcome in patients with acute central retinal artery occlusion of presumed thromboembolic etiology treated with LIF administered in aliquots with that of patients treated with standard therapy...
  20. pmc Ischemic stroke in children with critical illness: a poor prognostic sign
    Lori C Jordan
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Pediatr Neurol 36:244-6. 2007
    ..Mortality resulted primarily from the underlying illness. Prognosis after stroke is markedly worsened in children with premorbid critical illness...
  21. pmc Mechanisms of cerebral injury from cardiac surgery
    Charles W Hogue
    Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Crit Care Clin 24:83-98, viii-ix. 2008
    ..Most emphasis has been placed in the past on the intraoperative interval as being the period of highest cerebral vulnerability. Many clinical cerebral events, however, occur in the postoperative period...
  22. doi request reprint Neuropsychological outcomes after coronary artery bypass grafting
    Ola A Selnes
    Cognitive Neuroscience Division, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2189, USA
    J Int Neuropsychol Soc 16:221-6. 2010
    ..Late cognitive changes do occur, but comparison with patients undergoing off-pump surgery or those being treated medically suggests that these changes are not specific to CABG or more specifically to the use of cardiopulmonary bypass...
  23. pmc Glycated haemoglobin and cognitive decline: the Atherosclerosis Risk in Communities (ARIC) study
    A L Christman
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Diabetologia 54:1645-52. 2011
    ..This study aimed to examine the association between diabetes and hyperglycaemia-assessed by HbA(1c)-and change in cognitive function in persons with and without diabetes...
  24. ncbi request reprint Neural regions essential for distinct cognitive processes underlying picture naming
    Jessica DeLeon
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Brain 130:1408-22. 2007
    ....
  25. ncbi request reprint Brain injury from cardiac bypass procedures
    Rebecca F Gottesman
    Department of Neurology, Johns Hopkins Hospital, Baltimore, Maryland, USA
    Semin Neurol 26:432-9. 2006
    ..Other techniques such as the use of an arterial filter are discussed, as are their potential benefits in the prevention of neurological complications...
  26. pmc Vitamin D and cognitive function and dementia risk in a biracial cohort: the ARIC Brain MRI Study
    A L C Schneider
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Eur J Neurol 21:1211-8, e69-70. 2014
    ..Measuring 25(OH)D in late middle age before poor cognition affects behavior may provide clearer results...
  27. pmc Crossed cerebellar diaschisis in acute stroke detected by dynamic susceptibility contrast MR perfusion imaging
    D D M Lin
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    AJNR Am J Neuroradiol 30:710-5. 2009
    ....
  28. pmc Right hemispatial neglect: frequency and characterization following acute left hemisphere stroke
    Jonathan T Kleinman
    Johns Hopkins University School of Medicine, Department of Neurology, 600 North Wolfe Street, Phipps 126, Baltimore, MD 21287, USA
    Brain Cogn 64:50-9. 2007
    ..The distribution of USN types was different from the previously reported distribution following acute right hemisphere stroke. In this left hemisphere stroke population, allocentric neglect was more frequent than egocentric neglect...
  29. ncbi request reprint Predicting abnormal coagulation in ischemic stroke: reducing delay in rt-PA use
    Rebecca F Gottesman
    Cerebrovascular Division, Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Neurology 67:1665-7. 2006
    ..7% specificity. These results could be applied to rt-PA candidates and reduce potential delays...
  30. ncbi request reprint Watershed strokes after cardiac surgery: diagnosis, etiology, and outcome
    Rebecca F Gottesman
    Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Stroke 37:2306-11. 2006
    ..We investigated the role of intraoperative blood pressure in the development of watershed strokes and used MRI to evaluate diagnosis and outcomes associated with this stroke subtype...
  31. pmc Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium
    Stephanie Debette
    Department of Neurology, Boston University School of Medicine, Boston, Mass, USA
    Stroke 41:210-7. 2010
    ..We performed meta-analysis of genome-wide association studies of white participants in 6 studies comprising the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium...
  32. pmc Predictors and assessment of cognitive dysfunction resulting from ischaemic stroke
    Rebecca F Gottesman
    Department of Neurology, Baltimore, MD, USA
    Lancet Neurol 9:895-905. 2010
    ..As research is increasingly focused on the role of preventable risk factors in the development of dementia, the role of stroke in the development of cognitive impairment and dementia could be another target for prevention...
  33. ncbi request reprint Neurologic aspects of traumatic brain injury
    Rebecca F Gottesman
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Int Rev Psychiatry 15:302-9. 2003
    ..Finally, interventions such as induced hypothermia that can be undertaken to try to optimize outcome, are discussed along with current data in support of or against such techniques...
  34. doi request reprint Diffusion-weighted imaging showing 'pearls' predicts large-vessel disease as stroke etiology
    L Christine Turtzo
    Department of Neurology, University of Connecticut Health Center, Farmington, Connecticut, USA
    Cerebrovasc Dis 28:49-54. 2009
    ..In this retrospective study, we assessed whether DWI bright lesions termed 'pearls' predicted the presence of large-vessel arterial stenosis as the etiology of stroke...