D Brian Foster

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Redox signaling and protein phosphorylation in mitochondria: progress and prospects
    D Brian Foster
    Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Ross Research Building, Room 847, 720 Rutland Avenue, Baltimore, MD 21205, USA
    J Bioenerg Biomembr 41:159-68. 2009
  2. pmc A mighty small heart: the cardiac proteome of adult Drosophila melanogaster
    Anthony Cammarato
    Development and Aging Program, NASCR Center, Sanford Burnham Medical Research Institute, La Jolla, California, United States of America
    PLoS ONE 6:e18497. 2011
  3. pmc The cardiac acetyl-lysine proteome
    D Brian Foster
    Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    PLoS ONE 8:e67513. 2013
  4. pmc Mitochondrial ROMK channel is a molecular component of mitoK(ATP)
    D Brian Foster
    Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Circ Res 111:446-54. 2012
  5. pmc Redox regulation of mitochondrial ATP synthase: implications for cardiac resynchronization therapy
    Sheng bing Wang
    Department of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
    Circ Res 109:750-7. 2011
  6. pmc Combined effects of aging and inflammation on renin-angiotensin system mediate mitochondrial dysfunction and phenotypic changes in cardiomyopathies
    Tyesha N Burks
    Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine Baltimore, MD 21205, USA
    Oncotarget 6:11979-93. 2015
  7. pmc Nitroxyl-mediated disulfide bond formation between cardiac myofilament cysteines enhances contractile function
    Wei Dong Gao
    Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Circ Res 111:1002-11. 2012
  8. pmc Mitochondrial protein phosphorylation as a regulatory modality: implications for mitochondrial dysfunction in heart failure
    BRIAN O'ROURKE
    Department of Medicine, Division of Cardiology, The Johns Hopkins University, Baltimore, MD 21205 2195, USA
    Congest Heart Fail 17:269-82. 2011
  9. doi Integrated Omic Analysis of a Guinea Pig Model of Heart Failure and Sudden Cardiac Death
    D Brian Foster
    Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States
    J Proteome Res 15:3009-28. 2016
  10. pmc Identification and characterization of a functional mitochondrial angiotensin system
    Peter M Abadir
    Division of Geriatric Medicine and Gerontology, Biology of Healthy Aging Program, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    Proc Natl Acad Sci U S A 108:14849-54. 2011

Collaborators

Detail Information

Publications14

  1. pmc Redox signaling and protein phosphorylation in mitochondria: progress and prospects
    D Brian Foster
    Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Ross Research Building, Room 847, 720 Rutland Avenue, Baltimore, MD 21205, USA
    J Bioenerg Biomembr 41:159-68. 2009
    ....
  2. pmc A mighty small heart: the cardiac proteome of adult Drosophila melanogaster
    Anthony Cammarato
    Development and Aging Program, NASCR Center, Sanford Burnham Medical Research Institute, La Jolla, California, United States of America
    PLoS ONE 6:e18497. 2011
    ....
  3. pmc The cardiac acetyl-lysine proteome
    D Brian Foster
    Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    PLoS ONE 8:e67513. 2013
    ..New sites suggest a host of potential mechanisms by which excitation-contraction coupling may also be modulated. ..
  4. pmc Mitochondrial ROMK channel is a molecular component of mitoK(ATP)
    D Brian Foster
    Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Circ Res 111:446-54. 2012
    ..Activation of the mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) has been implicated in the mechanism of cardiac ischemic preconditioning, yet its molecular composition is unknown...
  5. pmc Redox regulation of mitochondrial ATP synthase: implications for cardiac resynchronization therapy
    Sheng bing Wang
    Department of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
    Circ Res 109:750-7. 2011
    ..Our recent studies have revealed that mitochondrial posttranslational modifications (PTM) may contribute to its benefits, motivating the present study of the oxidative regulation of mitochondrial ATP synthase...
  6. pmc Combined effects of aging and inflammation on renin-angiotensin system mediate mitochondrial dysfunction and phenotypic changes in cardiomyopathies
    Tyesha N Burks
    Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine Baltimore, MD 21205, USA
    Oncotarget 6:11979-93. 2015
    ..Moreover, treatment with an AT(1)R blocker, losartan, selectively reversed the signaling changes and ameliorated adverse phenotypic effects in the combination of aging and inflammation as well as each independently...
  7. pmc Nitroxyl-mediated disulfide bond formation between cardiac myofilament cysteines enhances contractile function
    Wei Dong Gao
    Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Circ Res 111:1002-11. 2012
    ..Nitroxyl (HNO), the one-electron-reduced form of nitric oxide, enhances cardiac function in a manner that suggests reversible cysteine modifications of the contractile machinery...
  8. pmc Mitochondrial protein phosphorylation as a regulatory modality: implications for mitochondrial dysfunction in heart failure
    BRIAN O'ROURKE
    Department of Medicine, Division of Cardiology, The Johns Hopkins University, Baltimore, MD 21205 2195, USA
    Congest Heart Fail 17:269-82. 2011
    ..The authors review phosphorylation as a mitochondrial regulatory strategy and highlight its possible role in the pathophysiology of cardiac hypertrophy and failure...
  9. doi Integrated Omic Analysis of a Guinea Pig Model of Heart Failure and Sudden Cardiac Death
    D Brian Foster
    Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States
    J Proteome Res 15:3009-28. 2016
    ....
  10. pmc Identification and characterization of a functional mitochondrial angiotensin system
    Peter M Abadir
    Division of Geriatric Medicine and Gerontology, Biology of Healthy Aging Program, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    Proc Natl Acad Sci U S A 108:14849-54. 2011
    ....
  11. pmc Creatine kinase-mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved
    Ashish Gupta
    Department of Medicine, Cardiology Division, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Clin Invest 122:291-302. 2012
    ..In addition, these data identify CK as a promising therapeutic target for preventing and treating HF and possibly diseases involving energy-dependent dysfunction in other organs with temporally varying energy demands...
  12. pmc CAPON modulates cardiac repolarization via neuronal nitric oxide synthase signaling in the heart
    Kuan Cheng Chang
    Institute of Molecular Cardiobiology, The Johns Hopkins University, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 105:4477-82. 2008
    ..Our findings provide a rationale for the association of CAPON gene variants with extremes of the QT interval in human populations...
  13. pmc Constitutive HIF-1α expression blunts the beneficial effects of cardiosphere-derived cell therapy in the heart by altering paracrine factor balance
    Michael Bonios
    Johns Hopkins University, Baltimore, MD 21205, USA
    J Cardiovasc Transl Res 4:363-72. 2011
    ..HIF-1α expression in CDCs blunted the beneficial functional effects of CDC transplantation, suggesting that paracrine factor balance may play an important role in cardiac regeneration...
  14. pmc Is Kir6.1 a subunit of mitoK(ATP)?
    D Brian Foster
    Institute of Molecular Cardiobiology, Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD, USA
    Biochem Biophys Res Commun 366:649-56. 2008
    ..1D-, 2D-, and native gel analyses were consistent with these assignments. The data suggest it is premature to assign Kir6.1 a role in mitoK(ATP) on the basis of immunoreactivity alone...