Stacey D Finley

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Compartment model predicts VEGF secretion and investigates the effects of VEGF trap in tumor-bearing mice
    Stacey D Finley
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Front Oncol 3:196. 2013
  2. pmc Effect of tumor microenvironment on tumor VEGF during anti-VEGF treatment: systems biology predictions
    Stacey D Finley
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Natl Cancer Inst 105:802-11. 2013
  3. pmc Predicting the effects of anti-angiogenic agents targeting specific VEGF isoforms
    Stacey D Finley
    Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA
    AAPS J 14:500-9. 2012
  4. pmc Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies
    Stacey D Finley
    Department of Biomedical Engineering, Johns Hopkins University, School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
    BMC Syst Biol 5:193. 2011
  5. pmc A two-compartment model of VEGF distribution in the mouse
    Phillip Yen
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 6:e27514. 2011
  6. pmc A multiscale computational model predicts distribution of anti-angiogenic isoform VEGF165b in peripheral arterial disease in human and mouse
    Liang Hui Chu
    Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, United States
    Sci Rep 6:37030. 2016
  7. pmc A systems biology view of blood vessel growth and remodelling
    Elizabeth A Logsdon
    Institute for Computational Medicine and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA
    J Cell Mol Med 18:1491-508. 2014

Collaborators

Detail Information

Publications7

  1. pmc Compartment model predicts VEGF secretion and investigates the effects of VEGF trap in tumor-bearing mice
    Stacey D Finley
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Front Oncol 3:196. 2013
    ..The model predictions also have implications for biomarker discovery with anti-angiogenic therapies. ..
  2. pmc Effect of tumor microenvironment on tumor VEGF during anti-VEGF treatment: systems biology predictions
    Stacey D Finley
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Natl Cancer Inst 105:802-11. 2013
    ..These models complement experimental studies and aid in the development of effective therapies targeting angiogenesis...
  3. pmc Predicting the effects of anti-angiogenic agents targeting specific VEGF isoforms
    Stacey D Finley
    Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA
    AAPS J 14:500-9. 2012
    ..Targeting VEGF(121) reduces tumor free VEGF and is an effective treatment strategy. Our results provide a basis for clinical investigation of isoform-specific anti-VEGF agents...
  4. pmc Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies
    Stacey D Finley
    Department of Biomedical Engineering, Johns Hopkins University, School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
    BMC Syst Biol 5:193. 2011
    ..The model is applied to investigate the action of VEGF-neutralizing agents (called "anti-VEGF") in the treatment of cancer...
  5. pmc A two-compartment model of VEGF distribution in the mouse
    Phillip Yen
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 6:e27514. 2011
    ..As the VEGF system becomes better characterized in other tissues and cell types, the model can be expanded to include additional compartments and vascular elements...
  6. pmc A multiscale computational model predicts distribution of anti-angiogenic isoform VEGF165b in peripheral arterial disease in human and mouse
    Liang Hui Chu
    Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, United States
    Sci Rep 6:37030. 2016
    ....
  7. pmc A systems biology view of blood vessel growth and remodelling
    Elizabeth A Logsdon
    Institute for Computational Medicine and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA
    J Cell Mol Med 18:1491-508. 2014
    ..We describe progress that has been made in applying computational modelling, quantitative biology and high-throughput experimentation to the angiogenesis process. ..