C D Ferris

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi Haem oxygenase-1 prevents cell death by regulating cellular iron
    C D Ferris
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Nat Cell Biol 1:152-7. 1999
  2. ncbi Atypical neural messengers
    D E Barañano
    Johns Hopkins University School of Medicine, Dept of Neuroscience, 725 N Wolfe Street, Baltimore, MD 21205, USA
    Trends Neurosci 24:99-106. 2001
  3. pmc Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy
    C C Watkins
    Department of Neuroscience, The Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA
    J Clin Invest 106:373-84. 2000
  4. ncbi Novel neurotransmitters and their neuropsychiatric relevance
    S H Snyder
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205 2185, USA
    Am J Psychiatry 157:1738-51. 2000
  5. ncbi Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease
    M Takahashi
    Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Neuron 28:461-73. 2000
  6. ncbi Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N
    K Ye
    Johns Hopkins University School of Medicine, Department of Neuroscience, North Wolfe Street 21205, Baltimore, MD, USA
    Cell 103:919-30. 2000
  7. ncbi Protein S-nitrosylation: a physiological signal for neuronal nitric oxide
    S R Jaffrey
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Nat Cell Biol 3:193-7. 2001
  8. pmc Purification of serine racemase: biosynthesis of the neuromodulator D-serine
    H Wolosker
    The Johns Hopkins University, School of Medicine, Departments of Neuroscience, Pharmacology and Molecular Sciences, and Psychiatry, 725 North Wolfe Street, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 96:721-5. 1999
  9. ncbi [3H]opipramol labels a novel binding site and sigma receptors in rat brain membranes
    C D Ferris
    Johns Hopkins University School of Medicine, Department of Neuroscience, Baltimore, Maryland 21205
    Mol Pharmacol 39:199-204. 1991
  10. ncbi Inositol 1,4,5-trisphosphate-activated calcium channels
    C D Ferris
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205
    Annu Rev Physiol 54:469-88. 1992

Collaborators

Detail Information

Publications12

  1. ncbi Haem oxygenase-1 prevents cell death by regulating cellular iron
    C D Ferris
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Nat Cell Biol 1:152-7. 1999
    ..Thus, cytoprotection by HO1 is attributable to its augmentation of iron efflux, reflecting a role for HO1 in modulating intracellular iron levels and regulating cell viability...
  2. ncbi Atypical neural messengers
    D E Barañano
    Johns Hopkins University School of Medicine, Dept of Neuroscience, 725 N Wolfe Street, Baltimore, MD 21205, USA
    Trends Neurosci 24:99-106. 2001
    ....
  3. pmc Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy
    C C Watkins
    Department of Neuroscience, The Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA
    J Clin Invest 106:373-84. 2000
    ..In diabetic animals, delayed gastric emptying can be reversed with a phosphodiesterase inhibitor, sildenafil. These findings have implications for novel therapeutic approaches and may clarify the etiology of diabetic gastropathy...
  4. ncbi Novel neurotransmitters and their neuropsychiatric relevance
    S H Snyder
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205 2185, USA
    Am J Psychiatry 157:1738-51. 2000
    ..The purpose of this review is to integrate insights regarding novel neurotransmitters or neuromodulators of neuropsychiatric significance...
  5. ncbi Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease
    M Takahashi
    Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Neuron 28:461-73. 2000
    ..These findings indicate that augmented neurotoxicity caused by APP-HO interactions may contribute to neuronal cell death in Alzheimer's disease...
  6. ncbi Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N
    K Ye
    Johns Hopkins University School of Medicine, Department of Neuroscience, North Wolfe Street 21205, Baltimore, MD, USA
    Cell 103:919-30. 2000
    ..Overexpression of 4.1N abolishes PIKE effects on PI3K. Activation of nuclear PI3K by PIKE is inhibited by the NGF-stimulated 4.1N translocation to the nucleus. Thus, PIKE physiologically modulates the activation by NGF of nuclear PI3K...
  7. ncbi Protein S-nitrosylation: a physiological signal for neuronal nitric oxide
    S R Jaffrey
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Nat Cell Biol 3:193-7. 2001
    ..Targets of NO include metabolic, structural and signalling proteins that may be effectors for neuronally generated NO. These findings establish protein S-nitrosylation as a physiological signalling mechanism for nNOS...
  8. pmc Purification of serine racemase: biosynthesis of the neuromodulator D-serine
    H Wolosker
    The Johns Hopkins University, School of Medicine, Departments of Neuroscience, Pharmacology and Molecular Sciences, and Psychiatry, 725 North Wolfe Street, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 96:721-5. 1999
    ..Properties such as pH optimum, Km values, and the requirement for pyridoxal phosphate resemble those of bacterial racemases, suggesting that the biosynthetic pathway for D-amino acids is conserved from bacteria to mammalian brain...
  9. ncbi [3H]opipramol labels a novel binding site and sigma receptors in rat brain membranes
    C D Ferris
    Johns Hopkins University School of Medicine, Department of Neuroscience, Baltimore, Maryland 21205
    Mol Pharmacol 39:199-204. 1991
    ..Because certain of these drugs are more potent at the haloperidol-resistant opipramol site than in exerting any other action, it is possible that this opipramol-selective site may mediate their therapeutic effects...
  10. ncbi Inositol 1,4,5-trisphosphate-activated calcium channels
    C D Ferris
    Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205
    Annu Rev Physiol 54:469-88. 1992
  11. pmc Targeted gene deletion of heme oxygenase 2 reveals neural role for carbon monoxide
    R Zakhary
    Department of Neuroscience, Johns Hopkins University School of Medicine, 725 North Wolfe Street Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 94:14848-53. 1997
    ..In nNOSDelta/Delta animals, NOS inhibitors selectively lost their efficacy, and HO inhibitors were inactive in HO-2(Delta)/Delta animals...
  12. pmc Carbon monoxide and nitric oxide as coneurotransmitters in the enteric nervous system: evidence from genomic deletion of biosynthetic enzymes
    L Xue
    Department of Physiology, Division of Gastroenterology, Mayo Clinic, Rochester, MN 55905, USA
    Proc Natl Acad Sci U S A 97:1851-5. 2000
    ....