Eric C Donny

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint Differential effects of response-contingent and response-independent nicotine in rats
    E C Donny
    Department of Psychology, University of Pittsburgh, 412 Langley Hall, Pittsburgh, PA 15260, USA
    Eur J Pharmacol 402:231-40. 2000
  2. ncbi request reprint High-dose methadone produces superior opioid blockade and comparable withdrawal suppression to lower doses in opioid-dependent humans
    Eric C Donny
    Behavioral Pharmacology Research Unit, Department of Psychiatry, Johns Hopkins School of Medicine, 5510 Nathan Shock Drive, Baltimore, MD 21224, USA
    Psychopharmacology (Berl) 161:202-12. 2002
  3. ncbi request reprint Using growth models to relate acquisition of nicotine self-administration to break point and nicotinic receptor binding
    Eric C Donny
    Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, 5510 Nathan Shock Drive, Baltimore, MD 21224, USA
    Drug Alcohol Depend 75:23-35. 2004
  4. ncbi request reprint Assessing the initiation of cocaine self-administration in humans during abstinence: effects of dose, alternative reinforcement, and priming
    Eric C Donny
    Behavioral Pharmacology Research Unit, Johns Hopkins School of Medicine, 5510 Nathan Shock Drive, Baltimore, MD 21224, USA
    Psychopharmacology (Berl) 172:316-23. 2004
  5. ncbi request reprint Choosing to take cocaine in the human laboratory: effects of cocaine dose, inter-choice interval, and magnitude of alternative reinforcement
    Eric C Donny
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, 5510 Nathan Shock Drive, Baltimore, MD 21224, USA
    Drug Alcohol Depend 69:289-301. 2003
  6. pmc The role of nicotine in smoking: a dual-reinforcement model
    Anthony R Caggiula
    Department of Psychology, 3131 Sennott Square, 210 South Bouquet Street, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Nebr Symp Motiv 55:91-109. 2009
  7. ncbi request reprint Operant responding for conditioned and unconditioned reinforcers in rats is differentially enhanced by the primary reinforcing and reinforcement-enhancing effects of nicotine
    Nadia Chaudhri
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA
    Psychopharmacology (Berl) 189:27-36. 2006
  8. pmc Reinforcement enhancing effect of nicotine and its attenuation by nicotinic antagonists in rats
    Xiu Liu
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Psychopharmacology (Berl) 194:463-73. 2007
  9. pmc Self-administered and noncontingent nicotine enhance reinforced operant responding in rats: impact of nicotine dose and reinforcement schedule
    Nadia Chaudhri
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA
    Psychopharmacology (Berl) 190:353-62. 2007
  10. pmc Conditioned reinforcement in rats established with self-administered nicotine and enhanced by noncontingent nicotine
    Matthew I Palmatier
    Department of Psychology, University of Pittsburgh, 3137 Sennott Square, Pittsburgh, PA 15260, USA
    Psychopharmacology (Berl) 195:235-43. 2007

Detail Information

Publications66

  1. ncbi request reprint Differential effects of response-contingent and response-independent nicotine in rats
    E C Donny
    Department of Psychology, University of Pittsburgh, 412 Langley Hall, Pittsburgh, PA 15260, USA
    Eur J Pharmacol 402:231-40. 2000
    ..These differences indicate that nicotine's acute effects are powerfully modified by the presence of a contingency relationship between drug administration and the animal's behavior and that this relationship develops very rapidly...
  2. ncbi request reprint High-dose methadone produces superior opioid blockade and comparable withdrawal suppression to lower doses in opioid-dependent humans
    Eric C Donny
    Behavioral Pharmacology Research Unit, Department of Psychiatry, Johns Hopkins School of Medicine, 5510 Nathan Shock Drive, Baltimore, MD 21224, USA
    Psychopharmacology (Berl) 161:202-12. 2002
    ..The efficacy of methadone for treating heroin dependence derives, in part, from suppression of opiate withdrawal and attenuation of the effects of heroin...
  3. ncbi request reprint Using growth models to relate acquisition of nicotine self-administration to break point and nicotinic receptor binding
    Eric C Donny
    Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, 5510 Nathan Shock Drive, Baltimore, MD 21224, USA
    Drug Alcohol Depend 75:23-35. 2004
    ..The relationships revealed demonstrate the usefulness of growth models in the quantitative analysis of individual differences in drug self-administration behavior...
  4. ncbi request reprint Assessing the initiation of cocaine self-administration in humans during abstinence: effects of dose, alternative reinforcement, and priming
    Eric C Donny
    Behavioral Pharmacology Research Unit, Johns Hopkins School of Medicine, 5510 Nathan Shock Drive, Baltimore, MD 21224, USA
    Psychopharmacology (Berl) 172:316-23. 2004
    ..One potential trigger of cocaine-taking is exposure to cocaine (i.e. priming)...
  5. ncbi request reprint Choosing to take cocaine in the human laboratory: effects of cocaine dose, inter-choice interval, and magnitude of alternative reinforcement
    Eric C Donny
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, 5510 Nathan Shock Drive, Baltimore, MD 21224, USA
    Drug Alcohol Depend 69:289-301. 2003
    ..Inter-choice interval did not affect cocaine choices. These results illustrate the persistence of cocaine self-administration once cocaine-taking has been initiated...
  6. pmc The role of nicotine in smoking: a dual-reinforcement model
    Anthony R Caggiula
    Department of Psychology, 3131 Sennott Square, 210 South Bouquet Street, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Nebr Symp Motiv 55:91-109. 2009
    ....
  7. ncbi request reprint Operant responding for conditioned and unconditioned reinforcers in rats is differentially enhanced by the primary reinforcing and reinforcement-enhancing effects of nicotine
    Nadia Chaudhri
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA
    Psychopharmacology (Berl) 189:27-36. 2006
    ....
  8. pmc Reinforcement enhancing effect of nicotine and its attenuation by nicotinic antagonists in rats
    Xiu Liu
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Psychopharmacology (Berl) 194:463-73. 2007
    ..Recent studies have demonstrated that nicotine can enhance operant responding for other nonpharmacological reinforcing stimuli. However, the nature of the reinforcement-enhancing effect of nicotine remains largely unknown...
  9. pmc Self-administered and noncontingent nicotine enhance reinforced operant responding in rats: impact of nicotine dose and reinforcement schedule
    Nadia Chaudhri
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA
    Psychopharmacology (Berl) 190:353-62. 2007
    ....
  10. pmc Conditioned reinforcement in rats established with self-administered nicotine and enhanced by noncontingent nicotine
    Matthew I Palmatier
    Department of Psychology, University of Pittsburgh, 3137 Sennott Square, Pittsburgh, PA 15260, USA
    Psychopharmacology (Berl) 195:235-43. 2007
    ..We have proposed that the reinforcement derived from these conditional stimuli can be inflated by a nonassociative "reinforcement-enhancing" effect of nicotine...
  11. ncbi request reprint Dissociating the primary reinforcing and reinforcement-enhancing effects of nicotine using a rat self-administration paradigm with concurrently available drug and environmental reinforcers
    Matthew I Palmatier
    Department of Psychology, University of Pittsburgh, 3137 Sennott Square, 210 S Bouquet St, Pittsburgh, PA 15260, USA
    Psychopharmacology (Berl) 184:391-400. 2006
    ..It serves as a primary reinforcer by increasing the probability of behaviors that result in nicotine delivery. However, nicotine also potently enhances behaviors that result in the delivery of nonpharmacological reinforcers...
  12. pmc The reinforcement enhancing effects of nicotine depend on the incentive value of non-drug reinforcers and increase with repeated drug injections
    Matthew I Palmatier
    Department of Psychology, University of Pittsburgh, 3137 Sennott Square, 210 S Bouquet Street, Pittsburgh, PA 15260, USA
    Drug Alcohol Depend 89:52-9. 2007
    ....
  13. pmc Metabotropic glutamate 5 receptor (mGluR5) antagonists decrease nicotine seeking, but do not affect the reinforcement enhancing effects of nicotine
    Matthew I Palmatier
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA
    Neuropsychopharmacology 33:2139-47. 2008
    ..These findings are consistent with other studies suggesting that mGlu5 receptors mediate nicotine seeking, but do not alter the reinforcement enhancing effects of nicotine...
  14. pmc Bupropion and nicotine enhance responding for nondrug reinforcers via dissociable pharmacological mechanisms in rats
    Matthew I Palmatier
    Department of Psychology, Kansas State University, Manhattan, KS 66502, USA
    Psychopharmacology (Berl) 207:381-90. 2009
    ..One of the most successful pharmacotherapies for smoking cessation, bupropion, also increases responding for nondrug reinforcers such as food and brain stimulation rewards...
  15. pmc Cue-induced reinstatement of nicotine-seeking behavior in rats: effect of bupropion, persistence over repeated tests, and its dependence on training dose
    Xiu Liu
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Psychopharmacology (Berl) 196:365-75. 2008
    ..In addition, the issue of whether bupropion (an FDA-approved smoking cessation medication) interferes with the conditioned incentive of nicotine cues remains to be addressed...
  16. pmc The role of nicotinic acetylcholine receptors in the primary reinforcing and reinforcement-enhancing effects of nicotine
    Matthew I Palmatier
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Neuropsychopharmacology 32:1098-108. 2007
    ..The two reinforcement-related effects of nicotine are mediated by nAChRs but can be dissociated by acute and chronic profiles...
  17. pmc Adolescent exposure to nicotine results in reinforcement enhancement but does not affect adult responding in rats
    Matthew T Weaver
    Department of Psychology, University of Pittsburgh, 210 S Bouquet Street, Pittsburgh, PA 15260, USA
    Drug Alcohol Depend 125:307-12. 2012
    ....
  18. pmc Precipitated withdrawal from nicotine reduces reinforcing effects of a visual stimulus for rats
    Matthew T Weaver
    Department of Psychology, School of Arts and Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Nicotine Tob Res 14:824-32. 2012
    ..However, the effects of continuous nicotine exposure on responding for a non-nicotine reinforcer are unknown, as are the effects of abruptly withdrawing continuous nicotine on behavior maintained by the same reinforcer...
  19. ncbi request reprint Operant responding for a visual reinforcer in rats is enhanced by noncontingent nicotine: implications for nicotine self-administration and reinforcement
    Eric C Donny
    Department of Psychiatry, Behavioral Pharmacology Research Unit, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Psychopharmacology (Berl) 169:68-76. 2003
    ..However, stimulant drugs also potentiate the rewarding effects of other reinforcers when administered noncontingently...
  20. pmc The relationship between cigarette use, nicotine dependence, and craving in laboratory volunteers
    Eric C Donny
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Nicotine Tob Res 10:934-42. 2008
    ..Further research into the sources of this variance is critical to understanding the process of and risk for nicotine dependence...
  21. ncbi request reprint Sex differences in the contribution of nicotine and nonpharmacological stimuli to nicotine self-administration in rats
    Nadia Chaudhri
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Psychopharmacology (Berl) 180:258-66. 2005
    ....
  22. ncbi request reprint Complex interactions between nicotine and nonpharmacological stimuli reveal multiple roles for nicotine in reinforcement
    Nadia Chaudhri
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Psychopharmacology (Berl) 184:353-66. 2006
    ..Although considerable progress has been made, we do not yet fully understand the behavioral and neurobiological basis of nicotine reinforcement, and without this knowledge, treatment strategies aimed at reducing smoking remain deficient...
  23. pmc Varenicline dose dependently enhances responding for nonpharmacological reinforcers and attenuates the reinforcement-enhancing effects of nicotine
    Melissa E Levin
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Nicotine Tob Res 14:299-305. 2012
    ..We assessed the effects of VAR alone and in combination with NIC (0.4 mg/kg) while rats pressed the lever for a moderately reinforcing visual stimulus (VS)...
  24. ncbi request reprint Methadone doses of 100 mg or greater are more effective than lower doses at suppressing heroin self-administration in opioid-dependent volunteers
    Eric C Donny
    Behavioral Pharmacology Research Unit, Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, MD, USA
    Addiction 100:1496-509. 2005
    ..This greater efficacy may result from greater cross-tolerance to the reinforcing effects of heroin...
  25. pmc Self-administered and yoked nicotine produce robust increases in blood pressure and changes in heart rate with modest effects of behavioral contingency in rats
    Eric C Donny
    Department of Psychology, University of Pittsburgh, 210 S Bouquet Street, Pittsburgh, PA 15260, USA
    Pharmacol Biochem Behav 99:459-67. 2011
    ..Effects of behavioral contingency were observed, but differences were limited. Other non-pharmacological factors such as baseline shifts potentially related to nicotine-associated cues deserve further attention...
  26. pmc Prolonged exposure to denicotinized cigarettes with or without transdermal nicotine
    Eric C Donny
    Department of Psychology, University of Pittsburgh, 3137 Sennott Square, 210 S Bouquet Street, Pittsburgh, PA 15217, USA
    Drug Alcohol Depend 104:23-33. 2009
    ....
  27. pmc Impact of tobacco regulation on animal research: new perspectives and opportunities
    Eric C Donny
    Department of Psychology, Dietrich School of Arts and Sciences, University of Pittsburgh, Pittsburgh, PA, USA
    Nicotine Tob Res 14:1319-38. 2012
    ..However, this approach is laden with potentially complex issues. Many of these complications can be studied using animal models, but they require a particular perspective...
  28. ncbi request reprint Importance of nonpharmacological factors in nicotine self-administration
    Anthony R Caggiula
    Department of Psychology, University of Pittsburgh, 3131 Sennott Square, 210 Bouquet Street, 15260, Pittsburgh, PA, USA
    Physiol Behav 77:683-7. 2002
    ....
  29. doi request reprint Delay discounting and smoking: association with the Fagerström Test for Nicotine Dependence but not cigarettes smoked per day
    Maggie M Sweitzer
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Nicotine Tob Res 10:1571-5. 2008
    ..These results suggest that DD among smokers is not simply the result of nicotine exposure, but may be an important marker for dependence, especially urgency to smoke in the morning...
  30. pmc Smoking Abstinence-Induced Changes in Resting State Functional Connectivity with Ventral Striatum Predict Lapse During a Quit Attempt
    Maggie M Sweitzer
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA
    Neuropsychopharmacology 41:2521-9. 2016
    ..These findings suggest that modulation of striatal connectivity with the cingulo-insular network during early withdrawal may be associated with smoking cessation outcomes. ..
  31. pmc Evaluation of a reduced nicotine product standard: Moderating effects of and impact on cannabis use
    Lauren R Pacek
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, 27705, USA Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21224, USA Electronic address
    Drug Alcohol Depend 167:228-32. 2016
    ..Research is needed to guide proposed regulations, including evaluation of consequences to public health. This study evaluated how a reduced nicotine product standard might be moderated by and impact cannabis use...
  32. pmc Differentiating the primary reinforcing and reinforcement-enhancing effects of varenicline
    Rachel L Schassburger
    Department of Neuroscience, University of Pittsburgh, A210 Langley Hall, 5th and Ruskin Avenue, Pittsburgh, PA, 15260, USA
    Psychopharmacology (Berl) 232:975-83. 2015
    ..Varenicline, when accompanied by non-drug cues, is self-administered by rats, though it is unclear whether this results from varenicline acting as a primary reinforcer or a reinforcement enhancer of the cues...
  33. ncbi request reprint Comparing the physiological and subjective effects of self-administered vs yoked cocaine in humans
    Eric C Donny
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA
    Psychopharmacology (Berl) 186:544-52. 2006
    ..Studies with laboratory animals demonstrating different effects of self- vs experimenter-administered drug suggest that the ability to control or predict drug delivery may be an important determinant of drug action...
  34. pmc Adolescent Rats Self-Administer Less Nicotine Than Adults at Low Doses
    Rachel L Schassburger
    Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA
    Nicotine Tob Res 18:1861-8. 2016
    ..The present study compared self-administration of low doses of nicotine between adolescent and adult rats...
  35. pmc Nicotine Enhances Footshock- and Lithium Chloride-Conditioned Place Avoidance in Male Rats
    Deanne M Buffalari
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA
    Nicotine Tob Res 18:1920-3. 2016
    ..To date, it is unclear whether NIC reinforcement enhancement serves to increase behaviors motivated by rewarding stimuli only, or whether NIC potentiates behavior motivated by all stimuli, regardless of valence...
  36. pmc Effects of MAO inhibition and a combination of minor alkaloids, β-carbolines, and acetaldehyde on nicotine self-administration in adult male rats
    Tracy T Smith
    Department of Psychology, University of Pittsburgh, United States
    Drug Alcohol Depend 155:243-52. 2015
    ..Although nicotine is the primary reinforcing constituent in cigarettes, there is evidence that other constituents in cigarette smoke may interact with nicotine to reinforce smoking behavior...
  37. pmc Nicotine enhances the expression of a sucrose or cocaine conditioned place preference in adult male rats
    Deanne M Buffalari
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA Electronic address
    Pharmacol Biochem Behav 124:320-5. 2014
    ..The present findings provide an additional mechanism that may underlie these effects and which may have implications for drug dependence and obesity. ..
  38. pmc Dependence and withdrawal-induced craving predict abstinence in an incentive-based model of smoking relapse
    Maggie M Sweitzer
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Nicotine Tob Res 15:36-43. 2013
    ..Development of laboratory models of relapse can provide a framework for identifying underlying mechanisms that may contribute to vulnerability. Here, we explored predictors of abstinence in a novel incentive-based model of relapse...
  39. pmc The reinforcement-enhancing effects of nicotine: implications for the relationship between smoking, eating and weight
    Eric C Donny
    Department of Psychology, University of Pittsburgh, 210 S Bouquet Street, Pittsburgh, PA 15260, USA
    Physiol Behav 104:143-8. 2011
    ..Better understanding of the mechanisms underlying the reinforcement-enhancing effects of nicotine broadly, and the effects on food reinforcement per se, may aid in the development of new treatments with better long term outcomes...
  40. ncbi request reprint Smoking in the absence of nicotine: behavioral, subjective and physiological effects over 11 days
    Eric C Donny
    Behavioral Pharmacology Research Unit, Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Addiction 102:324-34. 2007
    ..The purpose of this experiment was to characterize the effects of smoking stimuli delivered in the absence of nicotine over an extended (11-day) exposure...
  41. doi request reprint The relationship between cigarette use, nicotine dependence, and craving in laboratory volunteers
    Eric C Donny
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Nicotine Tob Res 10:447-55. 2008
    ..Further research into the sources of this variance is critical to understanding the process of and risk for nicotine dependence...
  42. doi request reprint Reducing nicotine exposure results in weight gain in smokers randomised to very low nicotine content cigarettes
    Laura E Rupprecht
    Center for Neuroscience at the University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Tob Control . 2016
    ..This potential regulatory action is hypothesised to improve public health by reducing smoking, but may have unintended consequences related to weight gain...
  43. pmc Effects of Monoamine Oxidase Inhibition on the Reinforcing Properties of Low-Dose Nicotine
    Tracy T Smith
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA
    Neuropsychopharmacology 41:2335-43. 2016
    ..If the FDA reduces the nicotine content of cigarettes, then variability in constituents that inhibit MAO-A could impact smoking. ..
  44. pmc Impact of smoking reduced nicotine content cigarettes on sensitivity to cigarette price: further results from a multi-site clinical trial
    Tracy T Smith
    University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA
    Addiction . 2016
    ..To assess the impact of a reduction in the nicotine content of cigarettes on estimated consumption of reduced nicotine cigarettes and usual brand cigarettes at a variety of hypothetical prices...
  45. doi request reprint The Impact of Smoking Very Low Nicotine Content Cigarettes on Alcohol Use
    Sarah S Dermody
    Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania
    Alcohol Clin Exp Res 40:606-15. 2016
    ..The secondary aim was to examine whether the effects of these cigarettes on alcohol outcomes were mediated by changes in nicotine exposure, smoking behavior, or withdrawal...
  46. pmc Low-dose nicotine self-administration is reduced in adult male rats naïve to high doses of nicotine: implications for nicotine product standards
    Tracy T Smith
    Department of Psychology, University of Pittsburgh
    Exp Clin Psychopharmacol 22:453-9. 2014
    ..If a nicotine reduction policy were implemented, then this policy may be especially effective at reducing acquisition of smoking...
  47. pmc Behavioral mechanisms underlying nicotine reinforcement
    Laura E Rupprecht
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA, 15260, USA
    Curr Top Behav Neurosci 24:19-53. 2015
    ..Gaining a better understanding of how nicotine impacts behavior will allow for maximally effective tobacco control efforts aimed at reducing the harm associated with tobacco use by reducing and/or treating its addictiveness. ..
  48. pmc Prevalence of and associations with waterpipe tobacco smoking among U.S. university students
    Brian A Primack
    Division of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Ann Behav Med 36:81-6. 2008
    ..Although waterpipe tobacco smoking seems to be increasing on U.S. university campuses, these data have come from convenience samples...
  49. ncbi request reprint Characterizing the relationship between increases in the cost of nicotine and decreases in nicotine content in adult male rats: implications for tobacco regulation
    Tracy T Smith
    Department of Psychology, University of Pittsburgh, 210 S Bouquet Street, Pittsburgh, PA, 15260, USA
    Psychopharmacology (Berl) 233:3953-3964. 2016
    ..Increasing the price of cigarettes (i.e., increasing reinforcer cost) would be considered an equivalent change in unit price to reducing nicotine content (i.e., reducing reinforcer magnitude)...
  50. pmc Self-Administered Nicotine Suppresses Body Weight Gain Independent of Food Intake in Male Rats
    Laura E Rupprecht
    Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA
    Nicotine Tob Res 18:1869-76. 2016
    ..The aim of this investigation was to examine the effects of self-administered nicotine on body weight and food intake in rats...
  51. pmc Gradual and immediate nicotine reduction result in similar low-dose nicotine self-administration
    Tracy T Smith
    Department of Psychology, School of Arts and Sciences, University of Pittsburgh, Pittsburgh, PA
    Nicotine Tob Res 15:1918-25. 2013
    ....
  52. doi request reprint Trajectories of smoking among freshmen college students with prior smoking history and risk for future smoking: data from the University Project Tobacco Etiology Research Network (UpTERN) study
    Craig R Colder
    Department of Psychology, State University of New York, University at Buffalo, Buffalo, NY, USA
    Addiction 103:1534-43. 2008
    ..Little is known about smoking during the transition to college. The current study examined trajectories of smoking among college freshmen, how trajectories predicted later smoking and the social context of smoking...
  53. pmc Obese Smokers as a Potential Subpopulation of Risk in Tobacco Reduction Policy
    Laura E Rupprecht
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania
    Yale J Biol Med 88:289-94. 2015
    ..We discuss the implications of nicotine-induced body weight suppression in obese smokers, as well as the possibility that obesity might increase susceptibility to smoking and nicotine dependence. ..
  54. doi request reprint Blunted striatal response to monetary reward anticipation during smoking abstinence predicts lapse during a contingency-managed quit attempt
    Maggie M Sweitzer
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, DUMC 3527, Durham, NC, USA
    Psychopharmacology (Berl) 233:751-60. 2016
    ..This bias toward smoking reward at the expense of alternative rewards is further exacerbated by deprivation from smoking, which may contribute to difficulty maintaining abstinence during a quit attempt...
  55. pmc Reduced nicotine product standards for combustible tobacco: building an empirical basis for effective regulation
    Eric C Donny
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA Electronic address
    Prev Med 68:17-22. 2014
    ..Hence, the health effects of nicotine reduction would likely be determined by changes in behavior that result in changes in smoke exposure...
  56. pmc Nicotine reduction as an increase in the unit price of cigarettes: a behavioral economics approach
    Tracy T Smith
    Department of Psychology, University of Pittsburgh, USA Electronic address
    Prev Med 68:23-8. 2014
    ..This paper reviews the utility of this approach and evaluates the notion that a reduction in nicotine content is equivalent to a reduction in the reinforcement value of smoking-an assumption made by the unit price approach. ..
  57. pmc Imaging genetics and the neurobiological basis of individual differences in vulnerability to addiction
    Maggie M Sweitzer
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Drug Alcohol Depend 123:S59-71. 2012
    ..Here, we present a model for merging these technologies to trace the links between genes, brain, and addictive behavior...
  58. pmc The absence of DSM-IV nicotine dependence in moderate-to-heavy daily smokers
    Eric C Donny
    Department of Psychology, University of Pittsburgh, 3137 Sennott Square, 210 S Bouquet Street, Pittsburgh, PA 15260, USA
    Drug Alcohol Depend 89:93-6. 2007
    ..Current theoretical models of nicotine dependence assume a close relationship between use and dependence; however, previous data suggest that many daily smokers fail to develop nicotine dependence...
  59. ncbi request reprint Environmental stimuli promote the acquisition of nicotine self-administration in rats
    Anthony R Caggiula
    Department of Psychology, University of Pittsburgh, 3131 Sennott Square, Pittsburgh, PA 15260, USA
    Psychopharmacology (Berl) 163:230-7. 2002
    ....
  60. ncbi request reprint Experimental evidence for a causal relationship between smoking lapse and relapse
    Laura M Juliano
    Department of Psychology, American University, Washington, DC 20016, USA
    J Abnorm Psychol 115:166-73. 2006
    ..Smoking outcomes did not differ between nicotine-containing and denicotinized cigarettes. The data suggest that stimulus factors may play an important role in lapse to relapse processes...
  61. doi request reprint Reducing the nicotine content of combusted tobacco products sold in New Zealand
    Eric C Donny
    Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Tob Control . 2016
    ..Policies that aim to render the most toxic tobacco products less addictive could help New Zealand attain their goal of becoming smokefree by 2025...
  62. pmc Threshold dose for discrimination of nicotine via cigarette smoking
    Kenneth A Perkins
    Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA, 15213, USA
    Psychopharmacology (Berl) 233:2309-17. 2016
    ..The lowest nicotine threshold "dose" in cigarettes discriminated from a cigarette containing virtually no nicotine may help inform the minimum dose maintaining dependence...
  63. pmc Greater reductions in nicotine exposure while smoking very low nicotine content cigarettes predict smoking cessation
    Sarah S Dermody
    Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Tob Control 24:536-9. 2015
    ..The roles of possible sources of nicotine were also explored, including the VLNC cigarette and co-use of cigarettes with normal nicotine content...
  64. ncbi request reprint Analyzing the acquisition of drug self-administration using growth curve models
    Stephanie T Lanza
    The Methodology Center, The Pennsylvania State University, 159 South Henderson, University Park, PA 16802, USA
    Drug Alcohol Depend 75:11-21. 2004
    ..Growth curve modeling captures the process of acquisition of drug self-administration and facilitates a greater understanding of the individual differences in change in drug-taking behavior over time...
  65. pmc Different lengths of times for progressions in adolescent substance involvement
    Ty A Ridenour
    The Pennsylvania State University, Prevention Research Center, State College 16801, United States
    Addict Behav 31:962-83. 2006
    ..Females had shorter transition times, though gender differences were small. Some evidence was found for a familial influence on transition times above what was accounted for by differences between substances...
  66. ncbi request reprint Guidelines on nicotine dose selection for in vivo research
    Shannon G Matta
    Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, 874 Union Avenue, Crowe 115, Memphis, TN 38163, USA
    Psychopharmacology (Berl) 190:269-319. 2007
    ..In many cases, such discrepancies could be attributed to the complex variables comprising species-specific in vivo responses to acute or chronic nicotine exposure...