Otavia L Caballero

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Effects of CT-Xp gene knock down in melanoma cell lines
    Otavia L Caballero
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, New York, USA
    Oncotarget 4:531-41. 2013
  2. pmc Systematic detection of putative tumor suppressor genes through the combined use of exome and transcriptome sequencing
    Qi Zhao
    Ludwig Collaborative Group, Department of Neurosurgery, Johns Hopkins University, 1550 Orleans Street, Baltimore, MD 21231, USA
    Genome Biol 11:R114. 2010
  3. pmc PLAC1, a trophoblast-specific cell surface protein, is expressed in a range of human tumors and elicits spontaneous antibody responses
    Wilson A Silva
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Cancer Immun 7:18. 2007
  4. doi request reprint Cancer/testis (CT) antigens: potential targets for immunotherapy
    Otavia L Caballero
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, New York City, USA
    Cancer Sci 100:2014-21. 2009
  5. doi request reprint Heat shock protein 90-mediated peptide-selective presentation of cytosolic tumor antigen for direct recognition of tumors by CD4(+) T cells
    Takemasa Tsuji
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Immunol 188:3851-8. 2012
  6. ncbi request reprint Cancer/testis antigens, gametogenesis and cancer
    Andrew J G Simpson
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
    Nat Rev Cancer 5:615-25. 2005
  7. pmc MAGE-A3 is highly expressed in a subset of colorectal cancer patients
    H M C Shantha Kumara
    Division of Colon and Rectal Surgery, Department of Surgery, St Luke s Roosevelt Hospital Center, New York, NY 10019, USA
    Cancer Immun 12:16. 2012
  8. pmc Expression of the cancer testis antigen IGF2BP3 in colorectal cancers; IGF2BP3 holds promise as a specific immunotherapy target
    Hmc Shantha Kumara
    Division of Colon and Rectal Surgery, Department of Surgery, Mount Sinai Roosevelt Hospital Center, Suite 7B, New York, USA
    Oncoscience 2:607-14. 2015
  9. ncbi request reprint Physical interaction of two cancer-testis antigens, MAGE-C1 (CT7) and NY-ESO-1 (CT6)
    Hearn J Cho
    Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA
    Cancer Immun 6:12. 2006
  10. pmc CT-X antigen expression in human breast cancer
    Anita Grigoriadis
    Ludwig Institute for Cancer Research, 605 Third Avenue, New York, NY 10158, USA
    Proc Natl Acad Sci U S A 106:13493-8. 2009

Collaborators

Detail Information

Publications15

  1. pmc Effects of CT-Xp gene knock down in melanoma cell lines
    Otavia L Caballero
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, New York, USA
    Oncotarget 4:531-41. 2013
    ..Our results suggest that GAGE, XAGE1 and SSX4 might each have a role in tumor progression and are possible therapeutic targets for the treatment of melanoma and other malignancies...
  2. pmc Systematic detection of putative tumor suppressor genes through the combined use of exome and transcriptome sequencing
    Qi Zhao
    Ludwig Collaborative Group, Department of Neurosurgery, Johns Hopkins University, 1550 Orleans Street, Baltimore, MD 21231, USA
    Genome Biol 11:R114. 2010
    ..The analysis was conducted on the breast cancer cell line HCC1954, and a lymphoblast cell line from the same individual, HCC1954BL...
  3. pmc PLAC1, a trophoblast-specific cell surface protein, is expressed in a range of human tumors and elicits spontaneous antibody responses
    Wilson A Silva
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Cancer Immun 7:18. 2007
    ..We found by ELISA that PLAC1 is immunogenic in a subset of cancer patients and healthy women. Its physical and expression characteristics render it a potential target for both active and passive cancer immunotherapeutic strategies...
  4. doi request reprint Cancer/testis (CT) antigens: potential targets for immunotherapy
    Otavia L Caballero
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, New York City, USA
    Cancer Sci 100:2014-21. 2009
    ..Cancer vaccine trials based on CT antigens MAGE-A3 and NY-ESO-1 are currently ongoing, and these antigens may also play a role in antigen-specific adoptive T-cell transfer and in the immunomodulation approach of cancer therapy...
  5. doi request reprint Heat shock protein 90-mediated peptide-selective presentation of cytosolic tumor antigen for direct recognition of tumors by CD4(+) T cells
    Takemasa Tsuji
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Immunol 188:3851-8. 2012
    ..Furthermore, targeted activation of tumor-recognizing CD4(+) T cells by vaccination or adoptive transfer could be a suitable strategy for enhancing the efficacy of tumor immunotherapy...
  6. ncbi request reprint Cancer/testis antigens, gametogenesis and cancer
    Andrew J G Simpson
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
    Nat Rev Cancer 5:615-25. 2005
    ....
  7. pmc MAGE-A3 is highly expressed in a subset of colorectal cancer patients
    H M C Shantha Kumara
    Division of Colon and Rectal Surgery, Department of Surgery, St Luke s Roosevelt Hospital Center, New York, NY 10019, USA
    Cancer Immun 12:16. 2012
    ..1%. Sero-reactivity specific for MAGE-A genes and PLAC1 was noted in 2.4% and 2.6% of patients, respectively. MAGE-A3 and PLAC1 may hold promise as vaccine targets for CRC. Further study is warranted...
  8. pmc Expression of the cancer testis antigen IGF2BP3 in colorectal cancers; IGF2BP3 holds promise as a specific immunotherapy target
    Hmc Shantha Kumara
    Division of Colon and Rectal Surgery, Department of Surgery, Mount Sinai Roosevelt Hospital Center, Suite 7B, New York, USA
    Oncoscience 2:607-14. 2015
    ..IGF2BP3 mRNA expression in colorectal cancers (CRC) has not been well studied. This study's aim was to quantitatively assess IGF2BP3 mRNA expression in CRC and, thus, determine if IGF2BP3 has potential as a vaccine target...
  9. ncbi request reprint Physical interaction of two cancer-testis antigens, MAGE-C1 (CT7) and NY-ESO-1 (CT6)
    Hearn J Cho
    Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA
    Cancer Immun 6:12. 2006
    ..This is the first report of direct interaction between two CT antigens and may be pertinent in the light of the frequently coordinated expression of these proteins...
  10. pmc CT-X antigen expression in human breast cancer
    Anita Grigoriadis
    Ludwig Institute for Cancer Research, 605 Third Avenue, New York, NY 10158, USA
    Proc Natl Acad Sci U S A 106:13493-8. 2009
    ..Because of the limited therapeutic options for ER-negative breast cancers, vaccines based on CT-X antigens might prove to be useful...
  11. doi request reprint NY-ESO-1 expression in meningioma suggests a rationale for new immunotherapeutic approaches
    Gilson S Baia
    Authors Affiliations New York Branch at Memorial Sloan Kettering Cancer Center, New York, New York
    Cancer Immunol Res 1:296-302. 2013
    ..Considering the limited treatment options for patients with meningioma, the potential of NY-ESO-1-based immunotherapy should be explored...
  12. pmc Monoclonal antibody MX35 detects the membrane transporter NaPi2b (SLC34A2) in human carcinomas
    Beatrice W T Yin
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Cancer Immun 8:3. 2008
    ..Membrane transporter molecules, such as NaPi2b, represent a new family of potential cell surface targets for the immunotherapy of cancer with monoclonal antibodies...
  13. ncbi request reprint Identification of the gonad-specific anion transporter SLCO6A1 as a cancer/testis (CT) antigen expressed in human lung cancer
    Sang Yull Lee
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Cancer Immun 4:13. 2004
    ..The analysis also permits us to estimate the eventual size of the SEREX-defined cancer immunome at around 4000 genes. This emphasizes the importance of continued SEREX screening to define the cancer immunome...
  14. pmc Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer
    Gary C Hon
    Ludwig Institute for Cancer Research, La Jolla, California 92093, USA
    Genome Res 22:246-58. 2012
    ....