Johns Hopkins University

Summary

Organization: Johns Hopkins University
Country: USA

Top Publications

  1. pmc Temporal discounting of reward and the cost of time in motor control
    Reza Shadmehr
    Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 30:10507-16. 2010
  2. ncbi Serotonin transporter genotype and acute subjective response to amphetamine
    David C Lott
    Linden Oaks Hospital at Edward, Naperville, Illinois, USA
    Am J Addict 15:327-35. 2006
  3. ncbi Cell biology. Extinguishing a cell cycle checkpoint
    M Andrew Hoyt
    Department of Biology, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA
    Science 313:624-5. 2006
  4. ncbi Synthesis and in vivo evaluation of a PET radioligand for imaging the endothelin-A receptor
    William B Mathews
    Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Nucl Med Biol 33:15-9. 2006
  5. ncbi A computational model of oxygen transport in skeletal muscle for sprouting and splitting modes of angiogenesis
    James W Ji
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 720 Rutland Avenue, 613 Traylor Bldg, Baltimore, MD 21205, USA
    J Theor Biol 241:94-108. 2006
  6. ncbi Mechanosensitive channels in the lateral wall can enhance the cochlear outer hair cell frequency response
    Alexander A Spector
    Department of Biomedical Engineering, Johns Hopkins University, 720 Rutland Avenue, Traylor 411, Baltimore, MD 21205, USA
    Ann Biomed Eng 33:991-1002. 2005
  7. ncbi Uterine fibroids: diffusion-weighted MR imaging for monitoring therapy with focused ultrasound surgery--preliminary study
    Michael A Jacobs
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Traylor Bldg, Room 217, 712 Rutland Ave, Baltimore, MD 21205, USA
    Radiology 236:196-203. 2005
  8. pmc Increasing the power of functional maps of the medial temporal lobe by using large deformation diffeomorphic metric mapping
    Michael I Miller
    Center for Imaging Science, The Whiting School of Engineering, The Johns Hopkins University, 301 Clark Hall, Baltimore, MD 21218, USA
    Proc Natl Acad Sci U S A 102:9685-90. 2005
  9. ncbi In vitro replication and repair of DNA containing a C2'-oxidized abasic site
    Marc M Greenberg
    Department of Chemistry, The Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, USA
    Biochemistry 43:15217-22. 2004
  10. ncbi A national neuroimaging database: a call to action
    David M Yousem
    The Russell H Morgan Department of Radiology and Radiological Sciences, The Johns Hopkins Hospital, 600 N Wolfe Street Phipps B 112, Baltimore, MD 21287, USA
    Acad Radiol 11:829-31. 2004

Research Grants

Detail Information

Publications62

  1. pmc Temporal discounting of reward and the cost of time in motor control
    Reza Shadmehr
    Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurosci 30:10507-16. 2010
    ..The cost depends on the value that the brain assigns to stimuli, and the rate at which it discounts this value in time. The motor commands that move our eyes reflect this cost of time...
  2. ncbi Serotonin transporter genotype and acute subjective response to amphetamine
    David C Lott
    Linden Oaks Hospital at Edward, Naperville, Illinois, USA
    Am J Addict 15:327-35. 2006
    ..The separate and combined analyses of the gene-linked polymorphic region (5-HTTLPR) and the Intron 2 VNTR suggest that these two HTT polymorphisms may contribute to acute subjective responses to d-amphetamine with a small effect...
  3. ncbi Cell biology. Extinguishing a cell cycle checkpoint
    M Andrew Hoyt
    Department of Biology, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA
    Science 313:624-5. 2006
  4. ncbi Synthesis and in vivo evaluation of a PET radioligand for imaging the endothelin-A receptor
    William B Mathews
    Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Nucl Med Biol 33:15-9. 2006
    ..72 and 1.31, respectively. Pretreatment with a 0.39 mg/kg dose of unlabeled ABT-627 inhibited the uptake of the tracer by 53-54% in both the myocardium and lungs at 65 min...
  5. ncbi A computational model of oxygen transport in skeletal muscle for sprouting and splitting modes of angiogenesis
    James W Ji
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 720 Rutland Avenue, 613 Traylor Bldg, Baltimore, MD 21205, USA
    J Theor Biol 241:94-108. 2006
    ..This study also shows that under the steady-state conditions the effect of myoglobin (Mb) on oxygen transport was small...
  6. ncbi Mechanosensitive channels in the lateral wall can enhance the cochlear outer hair cell frequency response
    Alexander A Spector
    Department of Biomedical Engineering, Johns Hopkins University, 720 Rutland Avenue, Traylor 411, Baltimore, MD 21205, USA
    Ann Biomed Eng 33:991-1002. 2005
    ..The effect of the channels is especially significant in an intermediate range of sound frequencies, and the channel-related gain is up to 3-4 times between 3 and 15 kHz...
  7. ncbi Uterine fibroids: diffusion-weighted MR imaging for monitoring therapy with focused ultrasound surgery--preliminary study
    Michael A Jacobs
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Traylor Bldg, Room 217, 712 Rutland Ave, Baltimore, MD 21205, USA
    Radiology 236:196-203. 2005
    ....
  8. pmc Increasing the power of functional maps of the medial temporal lobe by using large deformation diffeomorphic metric mapping
    Michael I Miller
    Center for Imaging Science, The Whiting School of Engineering, The Johns Hopkins University, 301 Clark Hall, Baltimore, MD 21218, USA
    Proc Natl Acad Sci U S A 102:9685-90. 2005
    ..Activation patterns are highly localized within the MTL. Whereas the present demonstration has been aimed at enhancing alignment within the MTL, this technique is general and can be applied throughout the brain...
  9. ncbi In vitro replication and repair of DNA containing a C2'-oxidized abasic site
    Marc M Greenberg
    Department of Chemistry, The Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, USA
    Biochemistry 43:15217-22. 2004
    ....
  10. ncbi A national neuroimaging database: a call to action
    David M Yousem
    The Russell H Morgan Department of Radiology and Radiological Sciences, The Johns Hopkins Hospital, 600 N Wolfe Street Phipps B 112, Baltimore, MD 21287, USA
    Acad Radiol 11:829-31. 2004
  11. ncbi Voltage-gated Na+ channels enhance the temporal filtering properties of electrosensory neurons in the torus
    Eric S Fortune
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland 21218, USA
    J Neurophysiol 90:924-9. 2003
    ..In addition, CD PSPs were blocked by intracellular application of either QX-314 or QX-222, whereas VD PSPs were not. These in vivo data suggest, therefore, that CD PSPs are mediated by voltage-dependent Na+ conductances...
  12. ncbi The alpha9/alpha10-containing nicotinic ACh receptor is directly modulated by opioid peptides, endomorphin-1, and dynorphin B, proposed efferent cotransmitters in the inner ear
    M I Lioudyno
    Department of Pharmacology, Tulane University, New Orleans, Louisiana 70112, USA
    Mol Cell Neurosci 20:695-711. 2002
    ..Because oocytes lack opioid receptors, it provides strong evidence for the direct interaction of opioid peptides with alpha9/alpha10nAChR...
  13. ncbi Biological response of chondrocytes to hydrogels
    J H Elisseeff
    Whitaker Institute of Biomedical Engineering, Department of Biomedical Engineering, Johns Hopkins University, 3400 N Charles Street, Baltimore, MD 21218, USA
    Ann N Y Acad Sci 961:118-22. 2002
    ..Further understanding of cell response to scaffolds will allow rational design and development of hydrogels for cartilage tissue engineering...
  14. ncbi Modeling and optimization in early detection programs with a single exam
    Giovanni Parmigiani
    Department of Oncology, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Biometrics 58:30-6. 2002
    ....
  15. pmc Disconnection of the amygdala central nucleus and the substantia innominata/nucleus basalis magnocellularis disrupts performance in a sustained attention task
    Peter C Holland
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD 21218, USA
    Behav Neurosci 121:80-9. 2007
    ..The lesions impaired performance under conditions of increased attentional load, suggesting that a circuit that includes CeA and SI/nBM regulates these aspects of attention...
  16. pmc Reinforcer-specificity of appetitive and consummatory behavior of rats after Pavlovian conditioning with food reinforcers
    Ezequiel M Galarce
    Department of Psychological and Brain Sciences, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, United States
    Physiol Behav 91:95-105. 2007
    ..The closer an action comes to ingestion, the more it is controlled by sensory properties conveyed by learned cues. These data are discussed in the context of allostatic regulation of food foraging and intake...
  17. ncbi What you set is not what you see: unconscious activation of cognitive control
    Carly J Leonard
    Department of Psychological and Brain Sciences, The Johns Hopkins University, Baltimore, Maryland 21218, USA
    J Neurosci 27:11170-1; discussion 11170. 2007
  18. pmc Differential effects of central injections of D1 and D2 receptor agonists and antagonists on male sexual behavior in Japanese quail
    H K Kleitz-Nelson
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD 21218, USA
    Eur J Neurosci 32:118-29. 2010
    ..Together, these data support the claim that dopamine specifically regulates male sexual behavior...
  19. doi Active testing for face detection and localization
    Raphael Sznitman
    Department of Computer Science, The Johns Hopkins University, CSEB Room 136, 3400 North Charles Street, Baltimore, MD 21218, USA
    IEEE Trans Pattern Anal Mach Intell 32:1914-20. 2010
    ..We show exponential gains in computation over traditional sliding window approaches, while keeping similar performance levels...
  20. pmc Hebbian analysis of the transformation of medial entorhinal grid-cell inputs to hippocampal place fields
    Francesco Savelli
    Zanvyl Krieger Mind Brain Institute, Johns Hopkins University, 338 Krieger Hall, 3400 N Charles St, Baltimore, MD 21218, USA
    J Neurophysiol 103:3167-83. 2010
    ....
  21. pmc Bridging neurocognitive aging and disease modification: targeting functional mechanisms of memory impairment
    M Gallagher
    Department of Psychological and Brain Science, Johns Hopkins University, Baltimore, MD 21218, USA
    Curr Alzheimer Res 7:197-9. 2010
    ....
  22. doi Real-time implementation of biofidelic SA1 model for tactile feedback
    A F Russell
    Department of Electrical and Computer Engineering at Johns Hopkins University, Baltimore, MD 21218, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:185-8. 2009
    ..Furthermore experiments were conducted to show that, like real SA1 fibers, the model's spike rate varies according to input pressure and that a periodic 'tapping' stimulus evokes periodic spike outputs...
  23. pmc A DNA-assisted binding assay for weak protein-protein interactions
    Katherine E Frato
    Department of Biology, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA
    J Mol Biol 394:805-14. 2009
    ..The DNA-assisted binding method may also prove useful in the study of other weak protein-protein interactions...
  24. pmc A surface topology and motion compensation system for microsurgery guidance and intervention based on common-path optical coherence tomography
    Kang Zhang
    Department of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA
    IEEE Trans Biomed Eng 56:2318-21. 2009
    ..In addition, the motion compensation properties are studied. The system can be easily integrated with microsurgery tools and can be used for various clinical applications...
  25. doi Carrier screening for cystic fibrosis in US genetic testing laboratories: a survey of laboratory directors
    D J Kaufman
    Genetics and Public Policy Center, Berman Institute of Bioethics, Johns Hopkins University, Washington, DC, USA
    Clin Genet 74:367-73. 2008
    ..Further studies are needed to determine whether the adoption of CF screening guidelines has significant clinical or economic effects on population-based CF screening programs...
  26. pmc Modeling cellular deformations using the level set formalism
    Liu Yang
    Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD 21218, USA
    BMC Syst Biol 2:68. 2008
    ..Here we demonstrate that accurate cell shape changes can be recreated using level set methods (LSM), in which the cellular shape is defined implicitly, thereby eschewing the need for updating boundaries...
  27. pmc Lack of concordance between fixation preference and HOTV optotype visual acuity in preschool children: the Baltimore Pediatric Eye Disease Study
    David S Friedman
    Dana Center for Prevention Ophthalmology, Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland 21210, USA
    Ophthalmology 115:1796-9. 2008
    ..To compare the results of fixation preference testing and standardized visual acuity testing in white and black children aged 30 through 71 months...
  28. pmc Excitatory and inhibitory learning with absent stimuli
    Daniel S Wheeler
    Department of Psychological and Brain Sciences, John Hopkins University, Baltimore, MD 21218, USA
    J Exp Psychol Anim Behav Process 34:247-55. 2008
    ..The results show the dynamic influence of temporal contiguity on mediated learning...
  29. doi The tactile perception of stimulus orientation
    S J Bensmaia
    Krieger Mind Brain Institute, Johns Hopkins University, Baltimore, MD 21218, USA
    Somatosens Mot Res 25:49-59. 2008
    ....
  30. ncbi Will magnetic resonance imaging (MRI)-based contrast agents for molecular receptor imaging make their way into the clinic?
    Kristine Glunde
    JHU ICMIC Program, Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Cell Mol Med 12:187-8. 2008
  31. ncbi Genomics and cancer
    Patrick Onyango
    Institute of Genetic Medicine and Department of Medicine, Johns Hopkins Medical School, Baltimore, Maryland 21205, USA
    Curr Opin Oncol 14:79-85. 2002
    ..This review addresses the opportunities and challenges that the availability of the human genome sequence holds for cancer research...
  32. ncbi Improved arterial compliance by a novel advanced glycation end-product crosslink breaker
    D A Kass
    Division of Cardiology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Circulation 104:1464-70. 2001
    ..We tested whether ALT-711, a novel nonenzymatic breaker of advanced glycation end-product crosslinks, selectively improves arterial compliance and lowers pulse pressure in older individuals with vascular stiffening...
  33. ncbi Chronic oxytocin pretreatment inhibits adenylyl cyclase activity in cultured rat myometrial cells
    K S Lindeman
    Department of Anesthesiology Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA
    Biol Reprod 59:1108-15. 1998
    ..25 microg/ml, 41 h) had no significant effect. These findings suggest that chronic oxytocin pretreatment desensitizes the adenylyl cyclase pathway by a cross-regulatory mechanism that involves activation of Gq and PKC...
  34. pmc Melatonin, immunity and cost of reproductive state in male European starlings
    G E Bentley
    Department of Psychology, Johns Hopkins University, Baltimore, MD 21218, USA
    Proc Biol Sci 265:1191-5. 1998
    ..These data are, we believe, the first to indicate a direct effect of reproductive state on immune function that is independent of both photoperiod (i.e., changes in the duration of melatonin secretion) and gonadal steroids...
  35. ncbi Comparison of three models for predicting blood lead levels in children: episodic exposures to lead
    J S LaKind
    Saphire Group, Inc, Bethesda, Maryland, USA
    J Expo Anal Environ Epidemiol 8:399-406. 1998
    ..It is hoped that this discussion will stimulate interest further researching exposure and health effects from episodic contact with lead contaminated media...
  36. pmc Direct visualization of antigen-specific T cells: HTLV-1 Tax11-19- specific CD8(+) T cells are activated in peripheral blood and accumulate in cerebrospinal fluid from HAM/TSP patients
    T F Greten
    Department of Oncology and Pathology, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross 364, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 95:7568-73. 1998
    ....
  37. ncbi A systems model for low vision rehabilitation. II. Measurement of vision disabilities
    R W Massof
    Lions Vision Research and Rehabilitation Center, Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Optom Vis Sci 75:349-73. 1998
    ..The need for rehabilitation to meet each goal is represented by "rehabilitative demand," a mathematical function of the measurements made of the value and difficulty of achieving each goal independently...
  38. ncbi A randomized controlled trial comparing the cuffed oropharyngeal airway and the laryngeal mask airway in spontaneously breathing anesthetized adults
    R S Greenberg
    Department of Anesthesiology Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Anesthesiology 88:970-7. 1998
    ..Specifically examined were ease of use, physiologic tolerance, and the frequency of problems...
  39. ncbi The effects of walls, paternity and ageing on sperm motility
    C C Gee
    Marine Sciences Program, University of South Carolina, Columbia, SC 29208, USA
    J Exp Biol 200:3185-92. 1997
    ..We conclude that viscous wall effects must be carefully considered in studies of sperm motility and chemotaxis. The analysis of sperm on a microscope slide may substantially exaggerate swimming speed...
  40. ncbi Assemblin, an essential herpesvirus proteinase
    W Gibson
    Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Drug Des Discov 15:39-47. 1997
    ..A brief summary of the synthesis, structure, and function of this fascinating enzyme is presented here...
  41. ncbi A meta-analysis of 61 sperm count studies revisited
    S Becker
    Department of Population Dynamics, School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Fertil Steril 67:1103-8. 1997
    ..To re-examine data on sperm counts over time from 61 studies from around the world...
  42. pmc Prevalence of antibodies to human papillomavirus (HPV) type 16 virus-like particles in relation to cervical HPV infection among college women
    R P Viscidi
    Eudowood Division of Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Clin Diagn Lab Immunol 4:122-6. 1997
    ..However, the assay appears to have adequate specificity and should be useful as an epidemiological marker of HPV-16 infection and sexual behavior...
  43. ncbi Ret 4, a positive acting rhodopsin regulatory element identified using a bovine retina in vitro transcription system
    S Chen
    Department of Ophthalmology, Wilmer Eye Institute, Baltimore, Maryland 21287 9289, USA
    J Biol Chem 271:28549-57. 1996
    ..Together, our results suggest that multiple promoter elements and transcriptional factors are involved in regulating photoreceptor-specific rhodopsin transcription...
  44. ncbi Analysis of wild-type and mutant aspartate aminotransferases using integrated rate equations
    M R Schiller
    Department of Chemistry and Biochemistry, Utah State University, Logan 84322, USA
    Biochim Biophys Acta 1297:17-27. 1996
    ....
  45. pmc Anticytomegaloviral activity of methotrexate associated with preferential accumulation of drug by cytomegalovirus-infected cells
    M Wachsman
    Division of Clinical Pharmacology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Antimicrob Agents Chemother 40:433-6. 1996
    ..Intracellular MTX in infected cells was almost entirely in the polyglutamated form, as demonstrated by thin-layer chromatography, whereas intracellular MTX was almost exclusively in the parent form in uninfected cells...
  46. ncbi Measles virus infection synergizes with IL-4 in IgE class switching
    F Imani
    Division of Clinical Immunology, Department of Medicine, Johns Hopkins University School of Medicine, Asthma and Allergy Center, Baltimore, MD 21224
    J Immunol 162:1597-602. 1999
    ..These data provide the first indication of a potential mechanism for MV-induced IgE up-regulation and suggest a model for a viral-induced exacerbation of IgE-mediated disorders such as asthma...
  47. ncbi Trends in educational placement and cost-benefit considerations in children with cochlear implants
    H W Francis
    Listening Center, Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Arch Otolaryngol Head Neck Surg 125:499-505. 1999
    ..To study the effect of cochlear implantation on the use of educational resources by profoundly hearing-impaired children and to determine trends in educational cost vs benefit...
  48. ncbi Directional abnormalities of vestibular and optokinetic responses in cerebellar disease
    M F Walker
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Ann N Y Acad Sci 871:205-20. 1999
    ..The findings are also consistent with prior animal-lesion studies that have shown a role for the vestibulocerebellum in the control of the direction of the VOR...
  49. ncbi Fatal infection after a bee sting
    A M Truskinovsky
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Clin Infect Dis 32:E36-8. 2001
    ..Life-threatening or even fatal bee infections can rarely develop after bee stings...
  50. ncbi The rationale for developing public health surveillance systems based on emergency department data
    J M Hirshon
    Department of Emergency Medicine, Johns Hopkins Bayview Medical Center, Baltimore, MD, USA
    Acad Emerg Med 7:1428-32. 2000
    ..This article describes current concepts and status of ED surveillance systems, their advantages and disadvantages, the rationale for their existence, and recommendations to allow their continued consideration and development...
  51. ncbi The safety and efficacy of parent-/nurse-controlled analgesia in patients less than six years of age
    C L Monitto
    Departments of Anesthesiology and Critical Care Medicine and Pediatrics, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Anesth Analg 91:573-9. 2000
    ..Nine children studied received naloxone, four (1.7%) for treatment of PNCA-related apnea or desaturation. All had improvement in their symptoms after naloxone administration...
  52. ncbi Risk factors for trachoma: 6-year follow-up of children aged 1 and 2 years
    Y H Hsieh
    Department of Pediatrics, School of Medicine, The Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Epidemiol 152:204-11. 2000
    ..75, 95% CI: 1.09, 12.98). The results suggest that risk factor reduction could diminish persistent disease...
  53. ncbi Feasibility of using recipients of health promotional newsletters for post-marketing surveillance
    L A Mead
    Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    J Clin Epidemiol 53:653-60. 2000
    ....
  54. pmc Dr Louis T. Wright and the NAACP: pioneers in hospital racial integration
    P P Reynolds
    Department of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Public Health 90:883-92. 2000
    ....
  55. ncbi Bedside vestibular examination
    M F Walker
    Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 6921, USA
    Otolaryngol Clin North Am 33:495-506. 2000
    ..Techniques for testing static and dynamic vestibulo-ocular and vestibulospinal function are summarized. Finally, the use of specific provocative maneuvers is described...
  56. ncbi Quantitative 1H MR spectroscopic imaging in early Rett syndrome
    A Horska
    Department of Radiology, Johns Hopkins University, School of Medicine, Baltimore, MD, USA
    Neurology 54:715-22. 2000
    ..To determine cerebral regional concentrations of N-acetyl aspartate (NAA), total choline (Cho), and total creatine (Cr) in Rett syndrome (RS) using 1H magnetic resonance spectroscopic imaging (MRSI)...
  57. ncbi Integrin polymorphisms as risk factors for thrombosis
    P F Bray
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Thromb Haemost 82:337-44. 1999
    ..Hand-in-hand with such clinical investigations, in vitro studies of the functional consequences of these inherited traits should provide a sound rationale for future interventions that will ultimately be beneficial to patients...
  58. ncbi Tumor angiogenesis, vascularization, and contrast-enhanced magnetic resonance imaging
    Z M Bhujwalla
    Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Top Magn Reson Imaging 10:92-103. 1999
    ..Contrast-enhanced magnetic resonance imaging techniques that currently are available for basic research and clinical applications to study various aspects of tumor angiogenesis and neovascularization are discussed...
  59. ncbi Steroid sensitive sites in the avian brain: does the distribution of the estrogen receptor alpha and beta types provide insight into their function?
    G F Ball
    Department of Psychology, Behavioral Neuroendocrinology Group, Johns Hopkins University, Baltimore, MD 21218 2686, USA
    Brain Behav Evol 54:28-40. 1999
    ....
  60. ncbi A comparison of job satisfaction among nursing assistants in nursing homes and the Program of All-inclusive Care for the Elderly (PACE)
    S M Friedman
    Johns Hopkins University, Baltimore, MD 21224, USA
    Gerontologist 39:434-9. 1999
    ....
  61. ncbi Operative management of Marfan syndrome: The Johns Hopkins experience
    W A Baumgartner
    Division of Cardiac Surgery, The Johns Hopkins Hospital, Baltimore, Maryland 21287 4618, USA
    Ann Thorac Surg 67:1859-60; discussion 1868-70. 1999
    ..Doctor Antoine Marfan described the first case of Marfan syndrome in 1896. It was over 50 years later that the development of aortic aneurysms and subsequent rupture was appreciated as the most life-threatening component of the syndrome...
  62. ncbi Clinical evaluation of the poisoned patient and toxic syndromes
    H K Liang
    Department of Emergency Medicine, Johns Hopkins Hospital, Baltimore, MD 21287 3080, USA
    Clin Chem 42:1350-5. 1996
    ..Rapid stabilization, resuscitation, and recognition of major toxic syndromes, along with appropriate utilization of laboratory testing, guide the clinician in the treatment of such patients...

Research Grants62

  1. PREVALENCE AND IMPACT OF GLAUCOMA AMONG THE VERY ELDERLY
    David Friedman; Fiscal Year: 2003
    ..Finally, the interactions between comorbidities (including cognitive deficits) and visual field loss will be explored. ..
  2. Amygdala systems in associative learning
    Peter Holland; Fiscal Year: 2007
    ..The proposed studies will clarify the CEA's roles in the modulation of basal forebrain cholinergic systems and midbrain-striatal dopamine systems in food-based associative learning. ..
  3. Peroxides for Chemotherapy of Malaria and Cancer
    Gary Posner; Fiscal Year: 2007
    ....
  4. Associatively-activated event representations
    Peter Holland; Fiscal Year: 2006
    ..The proposed research provides a basis for the understanding of basic processing of imaginal events in associative learning. ..
  5. Chemoprevention/Therapy Using Non-Calcemic Vitamin D
    Gary Posner; Fiscal Year: 2006
    ..Collectively, these studies will provide important structure- activity insights into the cancer chemoprotective and chemotherapeutic actions and molecular biology of vitamin D3 analogs. ..
  6. Role of amygdala systems in associative learning
    Peter Holland; Fiscal Year: 2005
    ..abstract_text> ..
  7. TRIOXANES FOR CHEMOTHERAPY OF MALARIA AND CANCER
    Gary Posner; Fiscal Year: 2005
    ....
  8. AMYGDALA SYSTEMS AND ASSOCIATIVE LEARNING
    Peter Holland; Fiscal Year: 1999
    ..The proposed behavioral and neurobiological studies may provide new insights into cognitive functions of the amygdala, as well as relations between cognitive and motivational functions in associative learning. ..
  9. MALARIA CHEMOTHERAPY AND CHEMOPROTECTION
    Gary Posner; Fiscal Year: 2000
    ....
  10. Seasonal Plasticity in Steroid-Sensitive Neural Circuits
    GREGORY BALL; Fiscal Year: 2007
    ..abstract_text> ..
  11. SEASONAL PLASTICITY IN STEROID SENSITIVE NEURAL CIRCUITS
    GREGORY BALL; Fiscal Year: 2001
    ..Seasonal changes in the songbird brain provide a unique model system to study how naturally occurring stimuli can modify brain morphology. ..
  12. STEROID/CATECHOLAMINE INTERACTIONS AND BEHAVIOR
    GREGORY BALL; Fiscal Year: 2002
    ..The study of steroid-neurotransmitter interactions also may provide insight into the etiology of sexually differentiated or steroid-dependent diseases. ..
  13. STEROID-CATECHOLAMINE INTERACTIONS AND SEX BEHAVIOR
    GREGORY BALL; Fiscal Year: 1993
    ..Finally, the fourth series of experiments will ask whether DA stimulates male sexual behavior by modulating the action of testosterone (changes in aromatization) or by acting on other steroid-dependent or -independent mechanisms...
  14. Steroid Catecholamine Interactions and Behavior
    GREGORY FRANCIS BALL; Fiscal Year: 2010
    ....