Samuel M Brown

Summary

Affiliation: Intermountain Medical Center
Country: USA

Publications

  1. pmc Defining and predicting severe community-acquired pneumonia
    Samuel M Brown
    Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center, University of Utah, Salt Lake City, Utah, USA
    Curr Opin Infect Dis 23:158-64. 2010
  2. pmc Multi-complexity measures of heart rate variability and the effect of vasopressor titration: a prospective cohort study of patients with septic shock
    Samuel M Brown
    Pulmonary and Critical Care, Intermountain Medical Center, Murray, UT, USA
    BMC Infect Dis 16:551. 2016
  3. pmc Prospective evaluation of an automated method to identify patients with severe sepsis or septic shock in the emergency department
    Samuel M Brown
    Pulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, USA
    BMC Emerg Med 16:31. 2016
  4. doi request reprint Balancing digital information-sharing and patient privacy when engaging families in the intensive care unit
    Samuel M Brown
    Center for Humanizing Critical Care, Intermountain Healthcare, 5121 S Cottonwood St, Murray, UT USA and Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City, UT, USA
    J Am Med Inform Assoc 23:995-1000. 2016
  5. pmc Coefficient of Variation of Coarsely Sampled Heart Rate is Associated With Early Vasopressor Independence in Severe Sepsis and Septic Shock
    Samuel M Brown
    Pulmonary and Critical Care, Intermountain Medical Center, Murray, UT, USA Pulmonary and Critical Care, University of Utah School of Medicine, Salt Lake City, UT, USA
    J Intensive Care Med 30:420-5. 2015
  6. pmc Validation of the Intermountain patient perception of quality (PPQ) survey among survivors of an intensive care unit admission: a retrospective validation study
    Samuel M Brown
    Pulmonary and Critical Care Medicine, Intermountain Medical Center, 5121 S Cottonwood St, Murray, UT, USA
    BMC Health Serv Res 15:155. 2015
  7. pmc Initial fractal exponent of heart rate variability is associated with success of early resuscitation in patients with severe sepsis or septic shock: a prospective cohort study
    Samuel M Brown
    Pulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, UT Pulmonary and Critical Care Medicine, University of Utah School of Medicine, Salt Lake City, UT Electronic address
    J Crit Care 28:959-63. 2013
  8. doi request reprint Withdrawal of nonfutile life support after attempted suicide
    Samuel M Brown
    University of Utah, UT, USA
    Am J Bioeth 13:3-12. 2013
  9. pmc Relationships among initial hospital triage, disease progression and mortality in community-acquired pneumonia
    Samuel M Brown
    Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Respirology 17:1207-13. 2012
  10. pmc Diastolic dysfunction and mortality in early severe sepsis and septic shock: a prospective, observational echocardiography study
    Samuel M Brown
    Division of Pulmonary and Critical Care Medicine, University of Utah School of Medicine, Salt Lake City, UT, 84132, USA
    Crit Ultrasound J 4:8. 2012

Collaborators

Detail Information

Publications40

  1. pmc Defining and predicting severe community-acquired pneumonia
    Samuel M Brown
    Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center, University of Utah, Salt Lake City, Utah, USA
    Curr Opin Infect Dis 23:158-64. 2010
    ..Community-acquired pneumonia is a significant clinical and public health problem. Defining and predicting severe pneumonia is difficult but important...
  2. pmc Multi-complexity measures of heart rate variability and the effect of vasopressor titration: a prospective cohort study of patients with septic shock
    Samuel M Brown
    Pulmonary and Critical Care, Intermountain Medical Center, Murray, UT, USA
    BMC Infect Dis 16:551. 2016
    ..Whether markers of heart rate complexity before vasopressor up-titration could be used to predict success of the up-titration is not known...
  3. pmc Prospective evaluation of an automated method to identify patients with severe sepsis or septic shock in the emergency department
    Samuel M Brown
    Pulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, USA
    BMC Emerg Med 16:31. 2016
    ..We aimed to produce a model that identifies 80 % of sepsis patients, with no more than 15 false positive alerts per day, within one hour of ED admission, using routine clinical data...
  4. doi request reprint Balancing digital information-sharing and patient privacy when engaging families in the intensive care unit
    Samuel M Brown
    Center for Humanizing Critical Care, Intermountain Healthcare, 5121 S Cottonwood St, Murray, UT USA and Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City, UT, USA
    J Am Med Inform Assoc 23:995-1000. 2016
    ....
  5. pmc Coefficient of Variation of Coarsely Sampled Heart Rate is Associated With Early Vasopressor Independence in Severe Sepsis and Septic Shock
    Samuel M Brown
    Pulmonary and Critical Care, Intermountain Medical Center, Murray, UT, USA Pulmonary and Critical Care, University of Utah School of Medicine, Salt Lake City, UT, USA
    J Intensive Care Med 30:420-5. 2015
    ..To determine whether variability of coarsely sampled heart rate and blood pressure early in the course of severe sepsis and septic shock predicts successful resuscitation, defined as vasopressor independence at 24 hours after admission...
  6. pmc Validation of the Intermountain patient perception of quality (PPQ) survey among survivors of an intensive care unit admission: a retrospective validation study
    Samuel M Brown
    Pulmonary and Critical Care Medicine, Intermountain Medical Center, 5121 S Cottonwood St, Murray, UT, USA
    BMC Health Serv Res 15:155. 2015
    ..Our objective was to evaluate the construct validity and internal consistency of the Intermountain Patient Perception of Quality (PPQ) survey among patients discharged from the ICU...
  7. pmc Initial fractal exponent of heart rate variability is associated with success of early resuscitation in patients with severe sepsis or septic shock: a prospective cohort study
    Samuel M Brown
    Pulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, UT Pulmonary and Critical Care Medicine, University of Utah School of Medicine, Salt Lake City, UT Electronic address
    J Crit Care 28:959-63. 2013
    ..We hypothesized that loss of complexity in HRV upon intensive care unit (ICU) admission would be associated with unsuccessful early resuscitation of sepsis...
  8. doi request reprint Withdrawal of nonfutile life support after attempted suicide
    Samuel M Brown
    University of Utah, UT, USA
    Am J Bioeth 13:3-12. 2013
    ....
  9. pmc Relationships among initial hospital triage, disease progression and mortality in community-acquired pneumonia
    Samuel M Brown
    Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Respirology 17:1207-13. 2012
    ..Worse outcomes from delayed intensive care unit (ICU) admission have long been suspected but have not been verified...
  10. pmc Diastolic dysfunction and mortality in early severe sepsis and septic shock: a prospective, observational echocardiography study
    Samuel M Brown
    Division of Pulmonary and Critical Care Medicine, University of Utah School of Medicine, Salt Lake City, UT, 84132, USA
    Crit Ultrasound J 4:8. 2012
    ..Patients with severe sepsis or septic shock often exhibit significant cardiovascular dysfunction. We sought to determine whether severity of diastolic dysfunction assessed by transthoracic echocardiography (TTE) predicts 28-day mortality...
  11. pmc Validation of the Infectious Disease Society of America/American Thoracic Society 2007 guidelines for severe community-acquired pneumonia
    Samuel M Brown
    Department of Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA
    Crit Care Med 37:3010-6. 2009
    ..Validate the Infectious Disease Society of America/American Thoracic Society 2007 (IDSA/ATS 2007) criteria for predicting severe community-acquired pneumonia (SCAP) and evaluate a health-services definition for SCAP...
  12. pmc Defining severe pneumonia
    Samuel M Brown
    Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center, Salt Lake City, UT, USA
    Clin Chest Med 32:469-79. 2011
    ..Outcome studies are needed to integrate human and health care system factors with the application of pneumonia severity definitions...
  13. pmc Right and left heart failure in severe H1N1 influenza A infection
    S M Brown
    Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, Utah, USA
    Eur Respir J 37:112-8. 2011
    ..RV basal dilatation was extremely common. These patients have less left heart failure than expected on the basis of prior descriptions of influenza myopericarditis or of general populations of septic patients...
  14. pmc Survival after shock requiring high-dose vasopressor therapy
    Samuel M Brown
    Pulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, UT 84107, USA
    Chest 143:664-71. 2013
    ..We sought to characterize survival among patients with shock requiring HDV. We also evaluated the possible utility of stress-dose corticosteroid therapy in these patients...
  15. pmc Multicenter implementation of a severe sepsis and septic shock treatment bundle
    Russell R Miller
    Division of Pulmonary and Critical Care Medicine, Intermountain Healthcare, Murray, UT, USA
    Am J Respir Crit Care Med 188:77-82. 2013
    ..Severe sepsis and septic shock are leading causes of intensive care unit (ICU) admission, morbidity, and mortality. The effect of compliance with sepsis management guidelines on outcomes is unclear...
  16. pmc A modified sequential organ failure assessment score for critical care triage
    Colin K Grissom
    Intermountain Medical Center, University of Utah, USA
    Disaster Med Public Health Prep 4:277-84. 2010
    ..We hypothesized that a modified SOFA (MSOFA) score that requires only 1 laboratory measurement would predict patient outcome as effectively as the SOFA score...
  17. pmc CURB-65 pneumonia severity assessment adapted for electronic decision support
    Barbara E Jones
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City, UT 84132, USA
    Chest 140:156-63. 2011
    ..The aim of this study was to determine whether an electronically generated severity estimate using CURB-65 elements as continuous and weighted variables better predicts 30-day mortality than the traditional CURB-65...
  18. pmc Preliminary Identification of Coping Profiles Relevant to Surrogate Decision Making in the ICU
    Jorie M Butler
    Geriatric Research Education and Clinical Center GRECC, George E Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah, United States of America
    PLoS ONE 11:e0166542. 2016
    ..Our study objective was to identify individual differences in coping with stress and information presentation preferences of respondents exposed to a simulated ICU experience...
  19. pmc Long-term outcomes after severe shock
    Cristina M Pratt
    Pulmonary and Critical Care Medicine, Intermountain Medical Center Center for Humanizing Critical Care, Intermountain Healthcare and Division of Pediatric Critical Care, University of Utah, Salt Lake City, Utah Kaiser Permanente Southern California, Pasadena, California Homer Warner Center for Informatics Research, Intermountain Healthcare, Murray, Utah Pulmonary and Critical Care Medicine, University of Utah School of Medicine, Salt Lake City, Utah and Psychology Department and Neuroscience Center, Brigham Young University, Provo, Utah
    Shock 43:128-32. 2015
    ..This study supports the observation that acute illness severity does not determine long-term outcomes. Even extremely critically ill patients have similar outcomes to general intensive care unit survivor populations...
  20. pmc Admission decisions and outcomes of community-acquired pneumonia in the homeless population: a review of 172 patients in an urban setting
    Barbara Jones
    Barbara Jones, Samuel M Brown, and Nathan C Dean are with the Divisions of Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City Adi V Gundlapalli is with the Division of Epidemiology, University of Utah, and The Department of Veterans Affairs, Salt Lake City Samuel M Brown and Nathan C Dean are also with Intermountain Medical Center, Murray, UT Jason P Jones is with Kaiser Permanente, Pasadena, CA, and Intermountain Medical Center, Murray
    Am J Public Health 103:S289-93. 2013
    ..We compared admission rates, outcomes, and performance of the CURB-65 mortality prediction score of homeless patients and nonhomeless patients with community-acquired pneumonia (CAP)...
  21. pmc Application of a simplified definition of diastolic function in severe sepsis and septic shock
    Michael J Lanspa
    Critical Care Echocardiography Service, Intermountain Medical Center, 5121 South Cottonwood Street, Murray, UT, 84157, USA
    Crit Care 20:243. 2016
    ....
  22. ncbi request reprint Relative Bradycardia in Patients With Septic Shock Requiring Vasopressor Therapy
    Sarah J Beesley
    1Division of Pulmonary and Critical Care, Intermountain Medical Center, Murray, UT 2Division of Pulmonary and Critical Care, University of Utah School of Medicine, Salt Lake City, UT 3Department of Anesthesia, University of Chicago, Chicago, IL 4Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA
    Crit Care Med . 2016
    ..The prevalence, determinants, and implications of relative bradycardia (heart rate, < 80 beats/min) in septic shock are unknown. To determine mortality associated with patients who are relatively bradycardic while in septic shock...
  23. ncbi request reprint A Clinician's Guide to Privacy and Communication in the ICU
    Leslie Francis
    1Department of Philosophy, University of Utah, Salt Lake City, UT 2S J Quinney College of Law, University of Utah, Salt Lake City, UT 3Armstrong Institute for Patient Safety and Quality, Johns Hopkins Medicine, Department of Medicine, School of Medicine, and Department of Health, Behavior, and Society, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 4Palo Alto Medical Foundation Research Institute, Palo Alto, CA 5Department of Medicine, University of California, Los Angeles, Los Angeles, CA 6Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA 7Division of General Internal Medicine, Harvard Medical School, Brigham and Women s Hospital, Boston, MA 8ARDS Foundation, Northbrook, IL 9Berman Institute of Bioethics Department of Medicine, School of Medicine and Department of Health Policy and Management, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 10Nursing, University of California San Francisco Medical Center, San Francisco, CA 11Center for Humanizing Critical Care, Intermountain Medical Center, Murray, UT 12Division of Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City, UT
    Crit Care Med . 2016
    ..To review the legal issues concerning family members' access to information when patients are in the ICU...
  24. pmc Association of left ventricular longitudinal strain with central venous oxygen saturation and serum lactate in patients with early severe sepsis and septic shock
    Michael J Lanspa
    Critical Care Echocardiography Service, Intermountain Medical Center, Salt Lake City, UT, USA
    Crit Care 19:304. 2015
    ..Ventricular strain is a non-invasive method of assessing ventricular wall deformation and may be a sensitive marker of heart function. We hypothesized that it may have a relationship with ScvO2 and lactate...
  25. pmc Mortality, morbidity, and disease severity of patients with aspiration pneumonia
    Michael J Lanspa
    Division of Pulmonary and Critical Care Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA
    J Hosp Med 8:83-90. 2013
    ..Aspiration pneumonia is a common syndrome, although less well characterized than other pneumonia syndromes. We describe a large population of patients with aspiration pneumonia...
  26. pmc Applying dynamic parameters to predict hemodynamic response to volume expansion in spontaneously breathing patients with septic shock
    Michael J Lanspa
    Division of Pulmonary and Critical Care Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Shock 39:155-60. 2013
    ..Vena cava collapsibility index and SVV predict hemodynamic response to fluid challenge patients with septic shock who are not mechanically ventilated. Optimal thresholds differ from those described in mechanically ventilated patients...
  27. pmc Clinical findings and demographic factors associated with ICU admission in Utah due to novel 2009 influenza A(H1N1) infection
    Russell R Miller
    Intermountain Medical Center, T4S, Respiratory Intensive Care Unit, 5121 S Cottonwood St, Murray, UT 84107, USA
    Chest 137:752-8. 2010
    ..Novel 2009 influenza A(H1N1) infection has significantly affected ICUs. We sought to characterize our region's clinical findings and demographic associations with ICU admission due to novel A(H1N1)...
  28. pmc Focused critical care echocardiography
    Achikam Oren-Grinberg
    1Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 2Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center and University of Utah School of Medicine, Salt Lake City, UT
    Crit Care Med 41:2618-26. 2013
    ..This review provides a current update on focused critical care echocardiography for the management of critically ill patients...
  29. pmc Polymorphisms in key pulmonary inflammatory pathways and the development of acute respiratory distress syndrome
    Samuel M Brown
    1Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Exp Lung Res 41:155-62. 2015
    ....
  30. pmc Glasgow Coma Scale score dominates the association between admission Sequential Organ Failure Assessment score and 30-day mortality in a mixed intensive care unit population
    Daniel B Knox
    Division of Pulmonary and Critical Care Medicine, University of Utah School of Medicine, Salt Lake City, UT
    J Crit Care 29:780-5. 2014
    ..We hypothesized that specific organ systems would have a greater association with mortality than others...
  31. pmc Structure, process, and annual ICU mortality across 69 centers: United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study
    William Checkley
    1Division of Pulmonary and Critical Care, Johns Hopkins University, Baltimore, MD 2Division of Pulmonary, Allergy, and Critical Care, Emory University, Atlanta, GA 3Division of Pulmonary and Critical Care, Intermountain Medical Center and University of Utah, Salt Lake City, UT 4Division of Pulmonary and Critical Care, University of Medicine and Dentistry of New Jersey, Newark, NJ 5Division of Pulmonary, Critical Care, and Environmental Medicine, University of Missouri Columbia, Columbia, MO 6Division of Pulmonary and Critical Care, Meharry Medical College, Nashville, TN 7Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN 8Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 9Department of Surgical Critical Care, University of Maryland, Baltimore, MD 10Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Ohio State University, Cleveland, OH 11Division of Acute Care Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, MI 12Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, USA
    Crit Care Med 42:344-56. 2014
    ..Hospital-level variations in structure and process may affect clinical outcomes in ICUs. We sought to characterize the organizational structure, processes of care, use of protocols, and standardized outcomes in a large sample of U.S. ICUs...
  32. pmc Central venous pressure and shock index predict lack of hemodynamic response to volume expansion in septic shock: a prospective, observational study
    Michael J Lanspa
    Division of Pulmonary and Critical Care Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA
    J Crit Care 27:609-15. 2012
    ..Central venous pressure (CVP) and shock index have been used independently to guide volume expansion, although their use is questionable. We hypothesize that a combination of these measurements will be useful...
  33. pmc Nonlinear Imputation of Pao2/Fio2 From Spo2/Fio2 Among Patients With Acute Respiratory Distress Syndrome
    Samuel M Brown
    Pulmonary and Critical Care Medicine Section, Intermountain Medical Center University of Utah School of Medicine, Murray, UT Electronic address
    Chest 150:307-13. 2016
    ..However, many patients with ARDS do not undergo blood gas measurement, which may result in underdiagnosis of the condition. As a consequence, a method for estimating Pao2 on the basis of noninvasive measurements is desirable...
  34. doi request reprint Satisfaction With Elimination of all Visitation Restrictions in a Mixed-Profile Intensive Care Unit
    Diane K Chapman
    At the time this article was researched Diane K Chapman was a staff nurse in the shock trauma intensive care unit and a member of the Center for Humanizing Critical Care at Intermountain Medical Center, Murray, Utah Dave S Collingridge is a statistician in the Statistical Data Center, Intermountain Healthcare, Murray, Brigham Young University, Provo, Utah and a researcher in the Department of Medicine, Pulmonary and Critical Care Division, Intermountain Medical Center Jorie M Butler is a health psychologist in the Center for Humanizing Critical Care associate director for education and evaluation at GRECC, core investigator at the IDEAS 2 0 at the Salt Lake Veterans Affairs Medical Center, Salt Lake City, Utah and an assistant professor in the Division of Geriatrics, Department of Internal Medicine, School of Medicine, University of Utah, Salt Lake City, Utah Samuel M Brown is director of the Center for Humanizing Critical Care, Intermountain Healthcare, Murray, Utah an assistant professor in the Department of Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City and an intensivist in the Department of Medicine, Pulmonary and Critical Care Division, Intermountain Medical Center
    Am J Crit Care 25:46-50. 2016
    ..Open and patient-tailored guidelines have been recommended as the preferred visitation model in critical care settings; however, many critical care units continue to restrict visitation...
  35. pmc Phenotypic clusters within sepsis-associated multiple organ dysfunction syndrome
    Daniel B Knox
    Pulmonary and Critical Care, Intermountain Medical Center, Salt Lake City, USA
    Intensive Care Med 41:814-22. 2015
    ..Identification of meaningfully distinct clusters may improve research, treatment and prognostication among septic patients. We therefore sought to identify clusters among patients with severe sepsis or septic shock...
  36. pmc Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome*
    Colin K Grissom
    1Division of Critical Care Medicine, Intermountain Medical Center, Murray, UT 2Division of Pulmonary and Critical Care, Department of Medicine, University of Utah, Salt Lake City, UT 3Division of Pediatric Critical Care, University of Utah, Salt Lake City, UT 4College of Pharmacy, University of Utah, Salt Lake City, UT 5Division of Nephrology, University of California San Francisco, San Francisco, CA 6Division of Critical Care Medicine, University of California San Francisco, San Francisco, CA 7Biostatistics Center, Massachusetts General Hospital, Boston, MA 8Division of Pulmonary and Critical Care Medicine, Baystate Medical Center, Springfield, MA 9Respiratory Institute, Cleveland Clinic, Cleveland, OH 10Department of Anesthesiology, University of Maryland, Baltimore, MD
    Crit Care Med 43:288-95. 2015
    ..The objective of this study was to compare the performance of FACTT Lite, FACTT Conservative, and FACTT Liberal protocols...
  37. doi request reprint Predictors of 6-month health utility outcomes in survivors of acute respiratory distress syndrome
    Samuel M Brown
    Center for Humanizing Critical Care, Intermountain Healthcare, Murray, Utah, USA Department of Medicine, Pulmonary and Critical Care Division, Intermountain Medical Center, Murray, Utah, USA Pulmonary and Critical Care, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Thorax . 2016
    ..We sought to identify variables associated with QOL, as measured by the EQ-5D health utility score, after ARDS using contemporary data science methods...
  38. doi request reprint Implementing a Mobility Program to Minimize Post-Intensive Care Syndrome
    Ramona O Hopkins
    Ramona O Hopkins is Professor, Department of Psychology and Neuroscience Center, Brigham Young University, Provo, Utah, and Clinical Research Investigator, Center for Humanizing Critical Care, and Department of Medicine, Pulmonary and Critical Care Division, Intermountain Healthcare, 5121 South Cottonwood St, Murray, UT 84107 Lorie Mitchell is Nurse Manager, Shock Trauma Intensive Care Unit, Department of Medicine, Intermountain Medical Center George E Thomsen is Medical Director, Coronary Intensive Care Unit, Department of Medicine, Intermountain Medical Center Michele Schafer is Member, Intensive Care Unit Patient Family Advisory Council, Intermountain Medical Center Maggie Link is Physical Therapist, Shock Trauma Intensive Care Unit, Intermountain Medical Center Samuel M Brown is Director, Center for Humanizing Critical Care, Assistant Professor of Pulmonary and Critical Care Medicine, Department of Medicine, Intermountain Healthcare, and University of Utah School of Medicine, Salt Lake City, Utah
    AACN Adv Crit Care 27:187-203. 2016
    ....
  39. doi request reprint Circulating Antiangiogenic Factors and Myocardial Dysfunction in Hypertensive Disorders of Pregnancy
    Sajid Shahul
    From the Department of Anesthesia and Critical Care S S, J N, A T, Section of Cardiology, Department of Medicine D M, R M L, and Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology S R, University of Chicago, IL Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston J B W, R T Center for Humanizing Critical Care, Intermountain Healthcare, Department of Medicine, University of Utah, Salt Lake City S M B Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA S B, S A K, S R Center for Vascular Biology, Department of Medicine S S, S A K and Department of Anesthesia, Critical Care and Pain Medicine A M, D T, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA and Department of Medicine, Cardiovascular Institute, University of Pennsylvania, Philadelphia Z A
    Hypertension 67:1273-80. 2016
    ..20 for sFlt1 and 0.19 for sEng, both P=0.01). Elevated circulating levels of antiangiogenic proteins in HDP correlate with and may contribute to myocardial dysfunction as measured by GLS. ..
  40. pmc Asking the right questions: the relationship between incident ventilator-associated pneumonia and mortality
    Michael J Lanspa
    Division of Pulmonary and Critical Care Medicine, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Crit Care 16:123. 2012
    ..In this complex area, which cannot be readily subjected to randomized controlled trials, studies should focus on the underlying questions of relevance, how to improve care of ventilated patients...