Kim A Lennox

Summary

Affiliation: Integrated DNA Technologies
Country: USA

Publications

  1. doi A direct comparison of anti-microRNA oligonucleotide potency
    Kim A Lennox
    Integrated DNA Technologies, 1710 Commercial Park, Coralville, Iowa 52241, USA
    Pharm Res 27:1788-99. 2010
  2. pmc Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides
    Kim A Lennox
    Integrated DNA Technologies, Inc, Coralville, IA 52241, USA
    Nucleic Acids Res 44:863-77. 2016
  3. ncbi Characterization of modified antisense oligonucleotides in Xenopus laevis embryos
    Kim A Lennox
    Integrated DNA Technologies, Coralville, IA 52241, USA
    Oligonucleotides 16:26-42. 2006

Collaborators

Detail Information

Publications3

  1. doi A direct comparison of anti-microRNA oligonucleotide potency
    Kim A Lennox
    Integrated DNA Technologies, 1710 Commercial Park, Coralville, Iowa 52241, USA
    Pharm Res 27:1788-99. 2010
    ..This study objectively evaluates the in vitro potency of different anti-miRNA oligonucleotides (AMOs) using various design and modification strategies described in the literature as well as some novel modification strategies...
  2. pmc Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides
    Kim A Lennox
    Integrated DNA Technologies, Inc, Coralville, IA 52241, USA
    Nucleic Acids Res 44:863-77. 2016
    ..A mixed-modality approach combining ASOs and RNAi reagents improved knockdown efficacy, particularly for those lncRNAs that localize to both nuclear and cytoplasmic compartments. ..
  3. ncbi Characterization of modified antisense oligonucleotides in Xenopus laevis embryos
    Kim A Lennox
    Integrated DNA Technologies, Coralville, IA 52241, USA
    Oligonucleotides 16:26-42. 2006
    ..However, at 400 nM, both of these compounds led to significant degradation of survivin mRNA, even when up to three mismatches were present in the heteroduplex...