- Genetic pathways and mutation profiles of human cancers: site- and exposure-specific patternsI A Lea
Integrated Laboratory Systems, Inc, Research Triangle Park, NC 27709, USA
Carcinogenesis 28:1851-8. 2007..05). Furthermore, the TP53 mutational hot spots for lung and laryngeal cancers from smokers included codons 157, 245 and 273, whereas for oral tumors included codons 280 and 281...
- Genetic pathways to colorectal cancerIsabel A Lea
Integrated Laboratory Systems Inc, Research Triangle Park, NC 27709, USA
Mutat Res 670:96-8. 2009..It is proposed that the higher incidence of mutation at codon 248 is a later event in colorectal tumorigenesis that occurs as the tumors become malignant...