Stephanie E Sen

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. ncbi request reprint Characterization and tissue-specific expression of two lepidopteran farnesyl diphosphate synthase homologs: implications for the biosynthesis of ethyl-substituted juvenile hormones
    Michel Cusson
    Natural Resources Canada, Canadian Forest Service, Laurentian Forestry Centre, Quebec City, Quebec G1V 4C7, Canada
    Proteins 65:742-58. 2006
  2. ncbi request reprint Arabidopsis thaliana plants possess a specific farnesylcysteine lyase that is involved in detoxification and recycling of farnesylcysteine
    Dring N Crowell
    Department of Biology, Indiana University Purdue University Indianapolis, 723 West Michigan Street, Indianapolis, IN 46202 5132, USA
    Plant J 50:839-47. 2007
  3. ncbi request reprint Juvenile hormone biosynthesis in moths: synthesis and evaluation of farnesol homologs as alternate substrates of farnesol oxidase
    S E Sen
    Department of Chemistry, Indiana University Purdue University Indianapolis IUPUI, 402 North Blackford Street, Indianapolis, IN 46202, USA
    Insect Biochem Mol Biol 33:601-7. 2003
  4. ncbi request reprint Partial purification of a farnesyl diphosphate synthase from whole-body Manduca sexta
    Stephanie E Sen
    Department of Chemistry, Indiana University Purdue University at Indianapolis, 402 North Blackford Street, Indianapolis, IN 46202, USA
    Insect Biochem Mol Biol 32:889-99. 2002
  5. ncbi request reprint Cloning, expression and characterization of a dipteran farnesyl diphosphate synthase
    Stephanie E Sen
    Department of Chemistry, Indiana U Purdue U Indianapolis IUPUI, 402 North Blackford Street, Indianapolis, IN 46202, USA
    Insect Biochem Mol Biol 37:1198-206. 2007
  6. ncbi request reprint Juvenile hormone biosynthesis in M. sexta: substrate specificity of insect prenyltransferase utilizing homologous diphosphate analogs
    Stephanie E Sen
    Department of Chemistry, Indiana University Purdue University Indianapolis IUPUI, 402 North Blackford Street, Indianapolis, IN 46202, USA
    Insect Biochem Mol Biol 36:827-34. 2006
  7. ncbi request reprint Prenyltransferase of larval and adult M. sexta corpora allata
    Stephanie E Sen
    Department of Chemistry, Indiana U Purdue U Indianapolis, 402 North Blackford Street, Indianapolis, IN 46202, USA
    Insect Biochem Mol Biol 37:29-40. 2007
  8. ncbi request reprint Purification, properties and heteromeric association of type-1 and type-2 lepidopteran farnesyl diphosphate synthases
    Stephanie E Sen
    Department of Chemistry, Indiana U Purdue U Indianapolis IUPUI, 402 North Blackford Street, Indianapolis, IN 46202, USA
    Insect Biochem Mol Biol 37:819-28. 2007
  9. doi request reprint Cloning, expression and characterization of lepidopteran isopentenyl diphosphate isomerase
    Stephanie E Sen
    Department of Chemistry, The College of New Jersey, 2000 Pennington Road, Ewing, NJ 08628, USA
    Insect Biochem Mol Biol 42:739-50. 2012
  10. pmc Farnesylcysteine lyase is involved in negative regulation of abscisic acid signaling in Arabidopsis
    David H Huizinga
    Department of Biology, Indiana University Purdue University Indianapolis, Indianapolis, IN 46202, USA
    Mol Plant 3:143-55. 2010

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Characterization and tissue-specific expression of two lepidopteran farnesyl diphosphate synthase homologs: implications for the biosynthesis of ethyl-substituted juvenile hormones
    Michel Cusson
    Natural Resources Canada, Canadian Forest Service, Laurentian Forestry Centre, Quebec City, Quebec G1V 4C7, Canada
    Proteins 65:742-58. 2006
    ..These results suggest that type-II FPPS plays a leading role in lepidopteran JH biosynthesis in spite of its apparently more conventional catalytic cavity...
  2. ncbi request reprint Arabidopsis thaliana plants possess a specific farnesylcysteine lyase that is involved in detoxification and recycling of farnesylcysteine
    Dring N Crowell
    Department of Biology, Indiana University Purdue University Indianapolis, 723 West Michigan Street, Indianapolis, IN 46202 5132, USA
    Plant J 50:839-47. 2007
    ..The effects of FCLY mutations on ABA sensitivity are even greater in the presence of exogenous FC. These data suggest that plants possess a specific FC detoxification and recycling pathway...
  3. ncbi request reprint Juvenile hormone biosynthesis in moths: synthesis and evaluation of farnesol homologs as alternate substrates of farnesol oxidase
    S E Sen
    Department of Chemistry, Indiana University Purdue University Indianapolis IUPUI, 402 North Blackford Street, Indianapolis, IN 46202, USA
    Insect Biochem Mol Biol 33:601-7. 2003
    ....
  4. ncbi request reprint Partial purification of a farnesyl diphosphate synthase from whole-body Manduca sexta
    Stephanie E Sen
    Department of Chemistry, Indiana University Purdue University at Indianapolis, 402 North Blackford Street, Indianapolis, IN 46202, USA
    Insect Biochem Mol Biol 32:889-99. 2002
    ..8+/-0.4 microM). The enzyme requires the presence of detergent, glycerol, and non-specific protein-protein interactions for stability and maximum catalytic activity...
  5. ncbi request reprint Cloning, expression and characterization of a dipteran farnesyl diphosphate synthase
    Stephanie E Sen
    Department of Chemistry, Indiana U Purdue U Indianapolis IUPUI, 402 North Blackford Street, Indianapolis, IN 46202, USA
    Insect Biochem Mol Biol 37:1198-206. 2007
    ..Although DmFPPS-1b does not efficiently couple homologous GPP compounds, homodimethylallyl diphosphate (HDMAPP), which is precursor to all homologous JH structures, was a reactive substrate...
  6. ncbi request reprint Juvenile hormone biosynthesis in M. sexta: substrate specificity of insect prenyltransferase utilizing homologous diphosphate analogs
    Stephanie E Sen
    Department of Chemistry, Indiana University Purdue University Indianapolis IUPUI, 402 North Blackford Street, Indianapolis, IN 46202, USA
    Insect Biochem Mol Biol 36:827-34. 2006
    ..sexta possesses high steric latitude at the (Z)-C-3 and C-7 alkyl positions of DMAPP and GPP, respectively, in contrast to other animal prenyltransferases but in keeping with the enzyme's presumptive role in homologous JH metabolism...
  7. ncbi request reprint Prenyltransferase of larval and adult M. sexta corpora allata
    Stephanie E Sen
    Department of Chemistry, Indiana U Purdue U Indianapolis, 402 North Blackford Street, Indianapolis, IN 46202, USA
    Insect Biochem Mol Biol 37:29-40. 2007
    ..Taken together, these results suggest that larval and adult prenyltransferase of M. sexta have distinct enzymological properties and that the adult CA possess more than one prenyltransferase...
  8. ncbi request reprint Purification, properties and heteromeric association of type-1 and type-2 lepidopteran farnesyl diphosphate synthases
    Stephanie E Sen
    Department of Chemistry, Indiana U Purdue U Indianapolis IUPUI, 402 North Blackford Street, Indianapolis, IN 46202, USA
    Insect Biochem Mol Biol 37:819-28. 2007
    ..These data suggest that type-1 and type-2 FPPSs can form a heteromer, which may play a role in sesquiterpene biosynthesis, such as JH homologue formation, in moths...
  9. doi request reprint Cloning, expression and characterization of lepidopteran isopentenyl diphosphate isomerase
    Stephanie E Sen
    Department of Chemistry, The College of New Jersey, 2000 Pennington Road, Ewing, NJ 08628, USA
    Insect Biochem Mol Biol 42:739-50. 2012
    ..fumiferana numbering) works in concert with a tyrosine residue (Y105) to allow binding of larger substrates and to stabilize the high-energy intermediate formed during substrate isomerization...
  10. pmc Farnesylcysteine lyase is involved in negative regulation of abscisic acid signaling in Arabidopsis
    David H Huizinga
    Department of Biology, Indiana University Purdue University Indianapolis, Indianapolis, IN 46202, USA
    Mol Plant 3:143-55. 2010
    ..These observations support the hypothesis that the ABA hypersensitive phenotype of fcly plants is the result of FC accumulation and inhibition of ICMT...
  11. doi request reprint Characterization of a novel aphid prenyltransferase displaying dual geranyl/farnesyl diphosphate synthase activity
    Sophie Vandermoten
    Gembloux Agricultural University, Department of Functional and Evolutionary Entomology, Passage des Déportés 2, B 5030 Gembloux, Belgium
    FEBS Lett 582:1928-34. 2008
    ..Analysis of an MpIPPS homology model pointed to substitutions that could confer GPP/FPP synthase activity to the aphid enzyme...