J W Brown

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. ncbi request reprint Caval division technique for sinus venosus atrial septal defect with partial anomalous pulmonary venous connection
    Ali Shahriari
    Department of Surgery, Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 81:224-9; discussion 229-30. 2006
  2. ncbi request reprint Fate of the autograft and homograft following Ross aortic valve replacement: reoperative frequency, outcome, and management
    John W Brown
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children and Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    J Heart Valve Dis 15:253-9; discusson 259-60. 2006
  3. doi request reprint Ross Versus Non-Ross Aortic Valve Replacement in Children: A 22-Year Single Institution Comparison of Outcomes
    John W Brown
    Department of Surgery, Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Indiana Electronic address
    Ann Thorac Surg 101:1804-10. 2016
  4. doi request reprint Transverse aortic arch obstruction: when to go from the front
    John W Brown
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA
    Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu . 2009
  5. doi request reprint Transcatheter Aortic Valve Replacement Versus Aortic Valve Bypass: A Comparison of Outcomes and Economics
    John W Brown
    Sections of Cardiothoracic Surgery, Indiana University Health and Indiana University School of Medicine, Indianapolis, Indiana Electronic address
    Ann Thorac Surg 101:49-54; discussion 54-5. 2016
  6. doi request reprint Surgical valvuloplasty versus balloon aortic dilation for congenital aortic stenosis: are evidence-based outcomes relevant?
    John W Brown
    Section of Cardiothoracic Surgery and Pediatric Cardiology, James W Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 94:146-53; discussion 153-5. 2012
  7. doi request reprint Evolution of mitral valve replacement in children: a 40-year experience
    John W Brown
    Division of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 93:626-33; discussion 633. 2012
  8. doi request reprint Ross root dilation in adult patients: is preoperative aortic insufficiency associated with increased late autograft reoperation?
    John W Brown
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, and Methodist Hospital, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 92:74-81; discussion 81. 2011
  9. ncbi request reprint The Ross-Konno procedure in children: outcomes, autograft and allograft function, and reoperations
    John W Brown
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 82:1301-6. 2006
  10. ncbi request reprint Valved bovine jugular vein conduits for right ventricular outflow tract reconstruction in children: an attractive alternative to pulmonary homograft
    John W Brown
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 82:909-16. 2006

Detail Information

Publications100

  1. ncbi request reprint Caval division technique for sinus venosus atrial septal defect with partial anomalous pulmonary venous connection
    Ali Shahriari
    Department of Surgery, Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 81:224-9; discussion 229-30. 2006
    ..We retrospectively compare the results of the internal patch repair versus the Warden technique...
  2. ncbi request reprint Fate of the autograft and homograft following Ross aortic valve replacement: reoperative frequency, outcome, and management
    John W Brown
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children and Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    J Heart Valve Dis 15:253-9; discusson 259-60. 2006
    ..The authors' institutional mid-term experience was reviewed to assess autograft and homograft hemodynamics, growth profile of the autograft, and reoperative frequency following Ross AVR...
  3. doi request reprint Ross Versus Non-Ross Aortic Valve Replacement in Children: A 22-Year Single Institution Comparison of Outcomes
    John W Brown
    Department of Surgery, Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Indiana Electronic address
    Ann Thorac Surg 101:1804-10. 2016
    ..This review compares the outcomes of 42 children who received a non-Ross AVR with 115 children undergoing Ross root replacement at our institution during the most recent 22 years...
  4. doi request reprint Transverse aortic arch obstruction: when to go from the front
    John W Brown
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA
    Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu . 2009
    ..The surgical management and timing of proximal aortic arch obstruction is controversial but almost always requires an approach via sternotomy using cardiopulmonary bypass...
  5. doi request reprint Transcatheter Aortic Valve Replacement Versus Aortic Valve Bypass: A Comparison of Outcomes and Economics
    John W Brown
    Sections of Cardiothoracic Surgery, Indiana University Health and Indiana University School of Medicine, Indianapolis, Indiana Electronic address
    Ann Thorac Surg 101:49-54; discussion 54-5. 2016
    ..Although TAVR and AVB were offered to similar patients at our center, comparisons of clinical outcomes and hospital economics for each strategy were not reported...
  6. doi request reprint Surgical valvuloplasty versus balloon aortic dilation for congenital aortic stenosis: are evidence-based outcomes relevant?
    John W Brown
    Section of Cardiothoracic Surgery and Pediatric Cardiology, James W Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 94:146-53; discussion 153-5. 2012
    ..Neonates less than 2 months of age were excluded from this comparison...
  7. doi request reprint Evolution of mitral valve replacement in children: a 40-year experience
    John W Brown
    Division of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 93:626-33; discussion 633. 2012
    ..This report reviews our 40-year experience with pediatric mitral valve replacement (MVR) with respect to mortality, valve-related morbidity, and reoperation risk factors...
  8. doi request reprint Ross root dilation in adult patients: is preoperative aortic insufficiency associated with increased late autograft reoperation?
    John W Brown
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, and Methodist Hospital, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 92:74-81; discussion 81. 2011
    ..Because of ongoing debate regarding the durability of this procedure, long-term follow-up in a large adult Ross experience might be of interest...
  9. ncbi request reprint The Ross-Konno procedure in children: outcomes, autograft and allograft function, and reoperations
    John W Brown
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 82:1301-6. 2006
    ..We reviewed our institutional midterm experience to assess autograft and homograft hemodynamics, and management after a Ross-Konno procedure...
  10. ncbi request reprint Valved bovine jugular vein conduits for right ventricular outflow tract reconstruction in children: an attractive alternative to pulmonary homograft
    John W Brown
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 82:909-16. 2006
    ..Recently a valve-containing bovine jugular vein (Contegra, Medtronic, Inc, Minneapolis, MN) was introduced for clinical trials for a variety of patients requiring RVOT reconstruction...
  11. ncbi request reprint Mitral valve replacement with Ross II technique: initial experience
    John W Brown
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Ann Thorac Surg 81:502-7; discussion 507-8. 2006
    ..Pulmonary autograft mitral valve replacement (PA-MVR) was introduced clinically by Ross in 1967, but has been rarely utilized in North America and Europe. The aim of this study is to review our early experience with PA-MVR...
  12. ncbi request reprint Closed transventricular aortic valvotomy for critical aortic stenosis in neonates: outcomes, risk factors, and reoperations
    John W Brown
    Section of Cardiothoracic Surgery, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Ann Thorac Surg 81:236-42. 2006
    ..The optimal treatment, however, continues to be controversial and still has high morbidity and mortality in many centers. This study examined our late outcome, risks, and reoperations after the treatment of critical AS in neonates...
  13. ncbi request reprint Outcomes in patients with interrupted aortic arch and associated anomalies: a 20-year experience
    John W Brown
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children, Indiana University School of Medicine, 545 Barnhill Dr, EH 215, Indianapolis, IN 46202 5123, USA
    Eur J Cardiothorac Surg 29:666-73; discussion 673-4. 2006
    ..The surgical results for the repair of interrupted aortic arch (IAA) have evolved in recent years. We report our results for staged repair of this complex congenital malformation...
  14. ncbi request reprint Long-term results of apical aortic conduits in children with complex left ventricular outflow tract obstruction
    John W Brown
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Ann Thorac Surg 80:2301-8. 2005
    ..This report summarizes our clinical experience with apical aortic conduits in children with an emphasis on hemodynamic results, reoperation, and long-term follow-up...
  15. ncbi request reprint Pulmonary arteriovenous malformations in children after the Kawashima operation
    John W Brown
    Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Indianapolis, Indiana, USA
    Ann Thorac Surg 80:1592-6. 2005
    ....
  16. ncbi request reprint Right ventricular outflow tract reconstruction with an allograft conduit in non-ross patients: risk factors for allograft dysfunction and failure
    John W Brown
    James W Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 80:655-63; discussion 663-4. 2005
    ..A retrospective evaluation of our experience with use of AC in non-Ross patients for reconstruction of the RVOT was conducted to determine the risk factors for failure...
  17. ncbi request reprint Surgical treatment of absent pulmonary valve syndrome associated with bronchial obstruction
    John W Brown
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 82:2221-6. 2006
    ..This retrospective study summarizes our 20-year experience of surgical treatment in patients with APVS...
  18. ncbi request reprint Incidence of and risk factors for pulmonary autograft dilation after Ross aortic valve replacement
    John W Brown
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 83:1781-7; discussion 1787-9. 2007
    ..All consecutive adult and pediatric patients who underwent Ross procedure at our institution were retrospectively reviewed for autograft dilation...
  19. doi request reprint Performance of SynerGraft decellularized pulmonary homograft in patients undergoing a Ross procedure
    John W Brown
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 91:416-22; discussion 422-3. 2011
    ....
  20. doi request reprint Rastelli operation for transposition of the great arteries with ventricular septal defect and pulmonary stenosis
    John W Brown
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 91:188-93; discussion 193-4. 2011
    ..This report reviews our 20-year experience with the Rastelli procedure and attempts to compare our outcomes with those recently published using the Nikaidoh and REV procedures...
  21. doi request reprint Surgical strategies and outcomes in patients with supra-annular mitral ring: a single-institution experience
    John W Brown
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, IN 46202 5123, USA
    Eur J Cardiothorac Surg 38:556-60. 2010
    ..Management of SMR remains an important therapeutic challenge. SMR constitutes a small but inadequately described subset that has a relatively good outcome with appropriate management...
  22. doi request reprint Modification of the Ross aortic valve replacement to prevent late autograft dilatation
    John W Brown
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA
    Eur J Cardiothorac Surg 37:1002-7. 2010
    ..We present our early experience with reduction annuloplasty combined with prosthetic Dacron graft replacement of the aorta above the autograft to prevent late dilation after a Ross aortic root replacement...
  23. doi request reprint Performance of the CryoValve SG human decellularized pulmonary valve in 342 patients relative to the conventional CryoValve at a mean follow-up of four years
    John W Brown
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, 545 Barnhill Dr, EH 215, Indianapolis, IN 46202 5123, USA
    J Thorac Cardiovasc Surg 139:339-48. 2010
    ..This study compared clinical outcomes of patients receiving CryoValve SG decellularized pulmonary valves with those of patients receiving conventionally processed CryoValve pulmonary valves...
  24. doi request reprint Recurrent coarctation: is surgical repair of recurrent coarctation of the aorta safe and effective?
    John W Brown
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 88:1923-30; discussion 1930-1. 2009
    ..We reviewed our experience with surgical repair of recurrent coarctation of the aorta and compared it with our institutional experience with balloon aortoplasty...
  25. doi request reprint Right ventricular outflow tract reconstruction in Ross patients: does the homograft fare better?
    John W Brown
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children and Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 86:1607-12. 2008
    ..We hypothesized that durability of homograft RVOT reconstruction in the Ross AVR is improved secondary to orthotopic positioning and the ability to oversize the RV-PA homograft conduit in the Ross AVR...
  26. doi request reprint Does the degree of preoperative mitral regurgitation predict survival or the need for mitral valve repair or replacement in patients with anomalous origin of the left coronary artery from the pulmonary artery?
    John W Brown
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Ind 46202 5123, USA
    J Thorac Cardiovasc Surg 136:743-8. 2008
    ....
  27. ncbi request reprint Right ventricular outflow tract reconstruction with a polytetrafluoroethylene monocusp valve: a twelve-year experience
    John W Brown
    Section of Cardiothoracic Surgery, James Whitcomb Riley Hospital for Children and Indiana University School of Medicine, Indianapolis, Ind 46202 5123, USA
    J Thorac Cardiovasc Surg 133:1336-43. 2007
    ..Polytetrafluoroethylene monocusp leaflets demonstrated favorable characteristics in our animal studies and have been applied to a variety of right ventricular outflow tract reconstructions at our institution...
  28. ncbi request reprint Operative results and outcomes in children with Shone's anomaly
    John W Brown
    Section of Cardiothoracic Surgery, James Whitcomb Riley Hospital for Children and Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 79:1358-65. 2005
    ..This study reviews our results and outcomes in patients with staged repair for left ventricular outflow tract obstruction (LVOTO) and mitral valve reconstruction...
  29. doi request reprint Lateral tunnel Fontan in the current era: is it still a good option?
    John W Brown
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 89:556-62; discussion 562-3. 2010
    ..Given the current controversy regarding indications for a total extracardiac conduit Fontan, we reviewed the long-term outcomes after a LTF operation and compared them with recently published series using one or both techniques...
  30. ncbi request reprint Surgical repair of congenital supravalvular aortic stenosis in children
    John W Brown
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN 46202 5123, USA
    Eur J Cardiothorac Surg 21:50-6. 2002
    ..Supravalvular aortic stenosis (SVAS) is an uncommon congenital cardiac anomaly characterized by varying degrees of left ventricular outflow tract obstruction beginning distal to the aortic valve...
  31. ncbi request reprint Surgery for aortic stenosis in children: a 40-year experience
    John W Brown
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children, Indianapolis, Indiana, USA
    Ann Thorac Surg 76:1398-411. 2003
    ..The indications for surgery and the surgical techniques for AS are well established. This report focuses on the early and long-term outcomes in children with AS over a 40-year period...
  32. ncbi request reprint Surgical results in patients with double outlet right ventricle: a 20-year experience
    J W Brown
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children, and Indiana University School of Medicine, Indianapolis 46202 5123, USA
    Ann Thorac Surg 72:1630-5. 2001
    ..The objective of this study was to review our surgical strategy in children with double outlet right ventricle and to assess risk factors for early and late mortality and reoperation...
  33. ncbi request reprint Truncus arteriosus repair: outcomes, risk factors, reoperation and management
    J W Brown
    Section of Cardiothoracic Surgery, Indiana University Medical Center, 545 Barnhill Drive, EH 215, Indianapolis, IN 46202 5123, USA
    Eur J Cardiothorac Surg 20:221-7. 2001
    ..Truncus arteriosus (TA) continues to be associated with significant morbidity and mortality, but there have been clinically significant improvements with early repair...
  34. ncbi request reprint Arterial switch operation: factors impacting survival in the current era
    J W Brown
    Section of Cardiothoracic Surgery, Riley Hospital for Children, and Indiana University School of Medicine, Indianapolis 46202, USA
    Ann Thorac Surg 71:1978-84. 2001
    ..The arterial switch procedure has become the preferred procedure for the transposition of the great arteries (TGA) and Taussig-Bing anomaly. This analysis is intended to identify potential factors affecting survival in the current era...
  35. ncbi request reprint Surgical management of scimitar syndrome: an alternative approach
    John W Brown
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children and Indiana University School of Medicine, Indianapolis 46202 5123, USA
    J Thorac Cardiovasc Surg 125:238-45. 2003
    ..The aim of this study was to present an alternative approach to the surgical correction of scimitar syndrome...
  36. ncbi request reprint Dynamic changes of endothelin-1, nitric oxide, and cyclic GMP in patients with congenital heart disease
    K Bando
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children and Indiana University Medical Center, Indianapolis 46202 5123, USA
    Circulation 96:II-346-51. 1997
    ..Pulmonary hypertension causes major morbidity and mortality after congenital heart surgery, but its mechanism remains unclear...
  37. ncbi request reprint Biological versus mechanical aortic valve replacement in children
    M W Turrentine
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children, and Indiana University School of Medicine, Indianapolis 46202 5123, USA
    Ann Thorac Surg 71:S356-60. 2001
    ..Potential risks of anticoagulation with mechanical valves and degeneration of other biological substitutes have kindled interest in the Ross procedure. This study outlines the evolution of our 27-year experience with prosthetic devices...
  38. ncbi request reprint Clinical outcomes and indicators of normalization of left ventricular dimensions after Ross procedure in children
    J W Brown
    Section of the Cardiothoracic Surgery, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Semin Thorac Cardiovasc Surg 13:28-34. 2001
    ..Regression of LV dilatation and hypertrophy, good autograft valve function and durability, and a high survival rate suggest that the Ross procedure is preferred for most children who require aortic valve replacement...
  39. ncbi request reprint Repair of tetralogy of Fallot with anomalous coronary arteries coursing across the obstructed right ventricular outflow tract
    M Ruzmetov
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children and Indiana University Medical Center, Indianapolis, IN 46202, USA
    Pediatr Cardiol 26:537-42. 2005
    ..Outcomes are similar to those of other patients with TOF. The presence of ACA does not impose increased risk after this surgical strategy...
  40. ncbi request reprint Short- and long-term outcomes after large pulmonary resection for germ cell tumors after bleomycin-combination chemotherapy
    Rafael S Andrade
    Department of Surgery, Thoracic Division, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 78:1224-8; discussion 1228-9. 2004
    ..We undertook an institutional review to determine the outcome of large pulmonary resections after bleomycin-combination chemotherapy...
  41. ncbi request reprint Modified Fontan operation in patients with anomalies of systemic and pulmonary venous connection
    M Ruzmetov
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children and Indiana University Medical Center, Indianapolis, IN 46202, USA
    Pediatr Cardiol 26:608-13. 2005
    ....
  42. doi request reprint Simultaneous apicoaortic conduit placement and mitral valve replacement in an adolescent with porcelain aorta, aortic stenosis, and mitral stenosis
    Jeremy L Herrmann
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 88:998-1000. 2009
    ..In cases in which the degree of aortic calcification pre-empts manipulation of the coronary ostia, an apicoaortic conduit may offer a viable solution to improve left ventricular outflow obstruction...
  43. ncbi request reprint Neonatal cavopulmonary assist: pulsatile versus steady-flow pulmonary perfusion
    Cynthia D Myers
    Department of Surgery, Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Indianapolis, Indiana, USA
    Ann Thorac Surg 81:257-63. 2006
    ..We have previously demonstrated feasibility of neonatal cavopulmonary assist under steady-flow conditions. We hypothesized that pulsatile pulmonary perfusion would further improve pulmonary hemodynamics...
  44. doi request reprint Midterm results of Ross aortic valve replacement: a single-institution experience
    John W Brown
    Sections of Cardiothoracic Surgery, James W Riley Hospital for Children and Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 88:601-7; discussion 607-8. 2009
    ..We reviewed our institutional midterm experience to assess autograft and homograft hemodynamics and reoperative frequency after Ross aortic valve replacement...
  45. ncbi request reprint Twenty-four hour cardiopulmonary stability in a model of assisted newborn Fontan circulation
    Cynthia D Myers
    Department of Surgery, Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Indianapolis, Indiana, USA
    Ann Thorac Surg 81:264-70; discussion 270-1. 2006
    ..Cavopulmonary assist has the potential to eliminate critical dependence on the problematic systemic arterial shunt. We studied this support modality during a 24-hour period in a neonatal animal model of univentricular Fontan circulation...
  46. ncbi request reprint Evolution of the Fontan procedure in a single center
    K Bando
    Section of Cardiothoracic Surgery, Riley Hospital for Children, Indianapolis, Indiana, USA
    Ann Thorac Surg 69:1873-9. 2000
    ..Surgical approaches to single ventricle variants include staged, fenestrated, and completed Fontan operations. This study compares outcomes with these modifications of the Fontan operation at a single center...
  47. ncbi request reprint Adrenomedullin in patients at high risk for pulmonary hypertension
    P Vijay
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis 46202 5125, USA
    Ann Thorac Surg 66:500-5. 1998
    ..Adrenomedullin is a newly identified peptide with profound hypotensive effects. We investigated perioperative adrenomedullin levels among patients with congenital heart disease with and without pulmonary hypertension...
  48. doi request reprint Rational approach to surgical management of complex forms of double outlet right ventricle with modified Fontan operation
    Mark Ruzmetov
    James W Riley Hospital for Children, Indiana University School of Medicine Cardiothoracic Surgery, Indianapolis, Indiana, USA
    Congenit Heart Dis 3:397-403. 2008
    ..The aim of this report is to analyze the results and risk factors of the FO performed as an alternative to the biventricular repair of complex DORV...
  49. ncbi request reprint Donor cardiac troponin T: a marker to predict heart transplant rejection
    P Vijay
    Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202 5125, USA
    Ann Thorac Surg 66:1934-9. 1998
    ..We studied the potential role of donor blood troponin T (Tn-T) as a marker for predicting heart transplant rejection...
  50. ncbi request reprint COPD may increase the incidence of refractory supraventricular arrhythmias following pulmonary resection for non-small cell lung cancer
    Y Sekine
    Department of Surgery, Indiana University Medical Center, Indianapolis, IN 46202, USA
    Chest 120:1783-90. 2001
    ..Although SVT was not an independent risk factor for death, a significantly longer hospitalization was observed...
  51. ncbi request reprint Staged surgical repair of functional single ventricle in infants with unobstructed pulmonary blood flow
    Mark D Rodefeld
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, James W Riley Hospital for Children, 545 Barnhill Dr, EH 215, Indianapolis, IN 46202 5123, USA
    Eur J Cardiothorac Surg 27:949-55. 2005
    ..We reviewed our experience with primary PAB in the subset of patients with SV-UPBF to identify risk factors for subsequent palliative procedures and Fontan completion...
  52. ncbi request reprint A prospective analysis of the incidence and risk factors associated with junctional ectopic tachycardia following surgery for congenital heart disease
    A S Batra
    Division of Cardiology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Pediatr Cardiol 27:51-5. 2006
    ..Longer ischemic time is the best predictor of JET. Patients undergoing arterial switch operation, AV canal repair, and Norwood repair are at highest risk of postoperative JET and should be considered for prophylactic therapy...
  53. ncbi request reprint Chronic outpatient sildenafil therapy for pulmonary hypertension in a child after cardiac surgery
    C A Knoderer
    Riley Hospital for Children, 702 Barnhill Drive, Room 1016, Indianapolis, IN 46202, USA
    Pediatr Cardiol 26:859-61. 2005
    ..To our knowledge, this is the first published report of long-term sildenafil treatment in a child after corrective cardiac surgery...
  54. doi request reprint Follow-up of surgical correction of aortic arch anomalies causing tracheoesophageal compression: a 38-year single institution experience
    Mark Ruzmetov
    Section of Pediatric Cardiothoracic Surgery, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN 46202 5123, USA
    J Pediatr Surg 44:1328-32. 2009
    ..In this study, we report a description of our approach and review of our 38-year experience in patients surgically treated for vascular rings...
  55. pmc Cavopulmonary assist for the univentricular Fontan circulation: von Kármán viscous impeller pump
    Mark D Rodefeld
    Section of Cardiothoracic Surgery, Department of Surgery, Indiana University School of Medicine and James Whitcomb Riley Hospital for Children, Indianapolis, Ind 46202, USA
    J Thorac Cardiovasc Surg 140:529-36. 2010
    ..An ideal means of providing mechanical cavopulmonary support does not exist. We hypothesized that a viscous impeller pump, based on the von Kármán viscous pump principle, is optimal for this role...
  56. ncbi request reprint Mediastinal metastases from testicular nonseminomatous germ cell tumors: patterns of dissemination and predictors of long-term survival with surgery
    Kenneth A Kesler
    Department of Surgery, Indiana University School of Medicine, Indianapolis, Ind, USA
    J Thorac Cardiovasc Surg 125:913-23. 2003
    ....
  57. ncbi request reprint Polytetrafluoroethylene monocusp valve technique for right ventricular outflow tract reconstruction
    Mark W Turrentine
    Department of Surgery, Division of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 74:2202-5. 2002
    ..Based on our clinical experience, it effectively prevents short-term and significantly reduces midterm pulmonary insufficiency without evidence of stenosis...
  58. ncbi request reprint Reoperative right ventricular outflow tract conduit reconstruction: risk analyses at follow up
    Mark D Rodefeld
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    J Heart Valve Dis 17:119-26; discussion 126. 2008
    ..The authors' experience of conduit RVOT reconstruction was reviewed in order to assess the frequency of conduit replacement and to determine risk factors for conduit dysfunction and failure...
  59. doi request reprint Carinaplasty airway closure: a technique for right pneumonectomy
    Kenneth A Kesler
    Department of Surgery, Cardiothoracic Division, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 85:1178-85; discussion 1185-6. 2008
    ..We reviewed our initial experience with a novel "carinaplasty" airway closure technique aimed at reducing the risks of bronchopleural fistula...
  60. doi request reprint Results of superior vena cava reconstruction with externally stented-polytetrafluoroethylene vascular prostheses
    Ikenna C Okereke
    Department of Cardiothoracic Surgery, Indiana University School of Medicine, 545 Barnhill Dr, EH 215, Indianapolis, IN 46204, USA
    Ann Thorac Surg 90:383-7. 2010
    ..We reviewed our institutional experience with SVC reconstruction using externally stented-polytetrafluoroethylene vascular prostheses...
  61. ncbi request reprint Surgical results of arterial switch operation for Taussig-Bing anomaly: is position of the great arteries a risk factor?
    Mark D Rodefeld
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children and Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 83:1451-7. 2007
    ..This study identifies the impact of the position of the great arteries and use of a staged surgical approach on the outcome after the arterial switch operation in children with Taussig-Bing anomaly...
  62. ncbi request reprint PTFE monocusp valve reconstruction of the right ventricular outflow tract
    Mark W Turrentine
    Department of Surgery, Indiana University School of Medicine, Indianapolis
    Ann Thorac Surg 73:871-9; discussion 879-80. 2002
    ..Polytetrafluoroethylene (PTFE, 0.1 mm) MO leaflets demonstrated favorable characteristics in animal studies, and the technique was applied to a variety of RVOTO anomalies...
  63. ncbi request reprint Prospective analysis of quality of life after surgical resection for esophageal cancer: preliminary results
    Jo Ann Brooks
    Thoracic Surgery Division, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Surg Oncol 81:185-94. 2002
    ..This pilot study prospectively evaluates the impact of esophageal resection on health-related quality of life (HRQL) and mood states at diagnosis and during the first year after surgery...
  64. ncbi request reprint On-pump coronary artery bypass surgery activates human myocardial NF-kappaB and increases TNF-alpha in the heart
    Daniel R Meldrum
    Department of Surgery and Medicine, Indiana Center for Vascular Biology and Medicine, Indiana University Medical Center, Indianapolis, Indiana, USA
    J Surg Res 112:175-9. 2003
    ..We hypothesized that CAB with cardiopulmonary bypass ("on-pump") activates human myocardial NF-kappaB and increases TNF in the heart...
  65. ncbi request reprint Intracellular signaling mechanisms of sex hormones in acute myocardial inflammation and injury
    Daniel R Meldrum
    Department of Surgery, Indiana University Medical Center, IB 461, Indianapolis, Indiana 46202, USA
    Front Biosci 10:1835-67. 2005
    ....
  66. ncbi request reprint Incidence, outcome, and risk factors for stroke after the Fontan procedure
    David S Chun
    Department of Pediatrics, Section of Cardiology, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Am J Cardiol 93:117-9. 2004
    ..A history of pulmonary artery banding was associated with an increased risk of stroke...
  67. ncbi request reprint Surgical salvage therapy for malignant intrathoracic metastases from nonseminomatous germ cell cancer of testicular origin: analysis of a single-institution experience
    Kenneth A Kesler
    Department of Surgery, Indiana Univeristy School of Medicine, Indianapolis, IN 46202, USA
    J Thorac Cardiovasc Surg 130:408-15. 2005
    ..We reviewed our institution's experience with patients undergoing salvage operations to remove malignant intrathoracic metastases...
  68. ncbi request reprint A retrospective analysis of locally advanced esophageal cancer patients treated with neoadjuvant chemoradiation therapy followed by surgery or surgery alone
    Kenneth A Kesler
    Department of Surgery, Thoracic Division, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 79:1116-21. 2005
    ..We conducted an institutional review of patients with locally advanced esophageal cancer who had complete pretreatment and surgical staging to identify variables predictive of outcome...
  69. ncbi request reprint Cavopulmonary assist: circulatory support for the univentricular Fontan circulation
    Mark D Rodefeld
    Section of Cardiothoracic Surgery, Department of Surgery, Indiana University School of Medicine and James Whitcomb Riley Hospital for Children, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 76:1911-6; discussion 1916. 2003
    ..We hypothesized that mechanical augmentation of cavopulmonary blood flow would provide physiologic stability in a model of cavopulmonary diversion and univentricular circulation...
  70. doi request reprint A 25-year single institution experience with surgery for primary mediastinal nonseminomatous germ cell tumors
    Kenneth A Kesler
    Department of Surgery, Cardiothoracic Division, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 85:371-8. 2008
    ..We reviewed our institution's 25-year experience in the cisplatin era to determine surgical risks and predictors of survival after surgery for PMNSGCT...
  71. ncbi request reprint Long-term survival after excision of a solitary esophageal cancer brain metastasis
    Kenneth A Kesler
    Indiana University School of Medicine, Department of Surgery, Thoracic Division, Indianapolis, Ind 46202, USA
    J Thorac Cardiovasc Surg 131:497-8. 2006
  72. ncbi request reprint Cavopulmonary assist in the neonate: an alternative strategy for single-ventricle palliation
    Mark D Rodefeld
    Department of Surgery, Section of Cardiothoracic Surgery, Indiana University School of Medicine, Emerson Hall 215, 545 Barnhill Drive, Indianapolis, IN 46202, USA
    J Thorac Cardiovasc Surg 127:705-11. 2004
    ..This was tested in a newborn animal model of total cavopulmonary diversion and univentricular Fontan circulation...
  73. ncbi request reprint After repair, atrioventricular valve regurgitation during cardiac extracorporeal membrane oxygenation predicts survival
    Tiffanie R Johnson
    Department of Pediatrics, Section of Pediatric Cardiology, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202 5225, USA
    Ann Thorac Surg 76:848-52. 2003
    ..We hypothesized that systemic atrioventricular (AV) valve regurgitation while on ECMO may be a better predictor of survival...
  74. ncbi request reprint Thoracoscopy-assisted Heller myotomy for the treatment of achalasia: results of a minimally invasive technique
    Kenneth A Kesler
    Department of Surgery, Thoracic Division, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Ann Thorac Surg 77:385-91; discussion 391-2. 2004
    ..Since 1998 our institution has utilized a minimally invasive thoracoscopy-assisted technique (ThAM) that allows a myotomy to be performed under direct visualization...
  75. ncbi request reprint Resolution of acquired pulmonary arteriovenous malformations in a patient with total anomalous systemic venous return
    T R Johnson
    Department of Pediatrics, Section of Pediatric Cardiology, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Riley Research 104, 702 Barnhill Drive, Indianapolis, IN 46202 5225, USA
    Pediatr Cardiol 23:210-2. 2002
    ..It reinforces the likelihood of the absence of an as yet unidentified hepatic vasoactive substance as the source for development of PAVMs...
  76. ncbi request reprint Primary mediastinal nonseminomatous germ cell tumors: the influence of postchemotherapy pathology on long-term survival after surgery
    K A Kesler
    Indiana University School of Medicine, Department of Surgery, Thoracic Division, Indianapolis, Indiana, USA
    J Thorac Cardiovasc Surg 118:692-700. 1999
    ..We reviewed the case histories of 91 patients treated at our institution from 1981 to 1998 with primary mediastinal nonseminomatous germ cell tumors to evaluate variables that may influence survival after surgery...
  77. ncbi request reprint Evolution of aortic valve replacement in children: a single center experience
    Mark Ruzmetov
    Section of Cardiothoracic Surgery, Indiana University Medical Center, 545 Barnhill Dr, EH 215, Indianapolis, IN 46202 5123, USA
    Int J Cardiol 113:194-200. 2006
    ..This has led many surgeons to the Ross procedure. This study outlines the evolution of our 30-year experience with AVR in children...
  78. ncbi request reprint Mitral valve replacement with the pulmonary autograft: Ross II procedure with Kabanni modification
    John W Brown
    Department of Surgery, Indiana University School of Medicine, Indianapolis 46202, USA
    Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 7:107-14. 2004
    ..We also review the world's experience with this technique. Mitral valve replacement with a pulmonary autograft (Ross II) is safe, reproducible, and possible warranted for selected patients...
  79. ncbi request reprint Hypoxic pulmonary vasoconstriction in cardiothoracic surgery: basic mechanisms to potential therapies
    Ben M Tsai
    Section of Cardiothoracic Surgery, Department of Surgery, Indianapolis, Indiana, USA
    Ann Thorac Surg 78:360-8. 2004
    ....
  80. ncbi request reprint Does endogenous testosterone mediate the lower preconditioning threshold in males?
    Nicholas T Nelson
    Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Surg Res 131:86-90. 2006
    ..Recent data indicates that males have lower preconditioning thresholds compared to females. Therefore, we hypothesized that testosterone may mediate the lower preconditioning threshold observed in males...
  81. ncbi request reprint 17-beta-Estradiol decreases p38 MAPK-mediated myocardial inflammation and dysfunction following acute ischemia
    Meijing Wang
    Department of Cardiothoracic Surgery, Indiana University Medical Center, 545 Barnhill Drive, Emerson Hall 215, Indianapolis, IN 46202, USA
    J Mol Cell Cardiol 40:205-12. 2006
    ..Further understanding of these mechanisms may allow therapeutic manipulation of sex hormones in the treatment of acute ischemic injury...
  82. ncbi request reprint Reduced pericardial levels of endostatin correlate with collateral development in patients with ischemic heart disease
    Vipul R Panchal
    Department of Medicine, Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, 46202, USA
    J Am Coll Cardiol 43:1383-7. 2004
    ....
  83. ncbi request reprint Thoracoscopic sympathectomy for hyperhidrosis palmaris: a periareolar approach
    K A Kesler
    Department of Surgery, Indiana University School of Medicine, Indianapolis 46202, USA
    Ann Thorac Surg 70:314-7. 2000
    ..Over the past 2 years, we have used a periareolar incision in eight patients to improve postoperative cosmesis for this benign condition...
  84. ncbi request reprint Aprotinin improves kidney function and decreases tubular cell apoptosis and proapoptotic signaling after renal ischemia-reperfusion
    Ajay Kher
    Department of Surgery, Indiana University Medical Center, Indianapolis, Ind, USA
    J Thorac Cardiovasc Surg 130:662-9. 2005
    ..The purpose of the study was to determine the effects of aprotinin on (1) renal function, (2) apoptosis and apoptotic signaling, and (3) the inflammatory response of the kidney after ischemia-reperfusion injury...
  85. doi request reprint Anterior pericardial tracheoplasty for long-segment tracheal stenosis: long-term outcomes
    Nervin Fanous
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, 545 Barnhill Dr, EH 215, Indianapolis, IN 46202 5123, USA
    J Thorac Cardiovasc Surg 139:18-23; discussion 23-5. 2010
    ..The purpose of this study is to examine the long-term results of anterior pericardial tracheoplasty...
  86. ncbi request reprint Surgical treatment of pulmonary artery sling and tracheal stenosis
    Andrew C Fiore
    Division of Pediatric Surgery, St Louis University Medical Center, St Louis, Missouri, USA
    Ann Thorac Surg 79:38-46; discussion 38-46. 2005
    ..The ideal operation remains controversial, with debate focusing on the need for left pulmonary artery for reimplantation and the technique of tracheal reconstruction...
  87. ncbi request reprint Aortic valve bypass for the high-risk patient with aortic stenosis
    James S Gammie
    Division of Cardiac Surgery, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
    Ann Thorac Surg 81:1605-10. 2006
    ..We have undertaken a programmatic effort to perform aortic valve bypass surgery as an alternative to conventional aortic valve replacement in selected high-risk patients, and now report our recent experience...
  88. ncbi request reprint Can pulmonary conduit dysfunction and failure be reduced in infants and children less than age 2 years at initial implantation?
    Tara Karamlou
    Division of Cardiovascular Surgery and Cardiology, Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 132:829-38. 2006
    ..We sought to examine risk factors for pulmonary conduit failure or dysfunction in infants less than age 2 years at initial implantation...
  89. doi request reprint Pulmonary valve replacement: a comparison of three biological valves
    Andrew C Fiore
    Division of Cardiothoracic Surgery, St Louis University School of Medicine, Cardinal Glennon Children s Hospital, St Louis, Missouri 63104, USA
    Ann Thorac Surg 85:1712-8; discussion 1718. 2008
    ..We retrospectively reviewed the performance of the mosaic porcine, bovine pericardial, and homograft prostheses for pulmonary valve replacement to correct chronic pulmonary insufficiency...
  90. ncbi request reprint Fontan operation: a comparison of lateral tunnel with extracardiac conduit
    Andrew C Fiore
    Division of Cardiothoracic Surgery, St Louis University School of Medicine Cardinal Glennon Children s Hospital, St Louis, Missouri 63104, USA
    Ann Thorac Surg 83:622-9; discussion 629-30. 2007
    ..The purpose of this report is to compare the outcome of the extracardiac (EC) with the lateral tunnel (LT) Fontan...
  91. ncbi request reprint P38 MAPK mediates myocardial proinflammatory cytokine production and endotoxin-induced contractile suppression
    Meijing Wang
    Department of Surgery, Section of Cardiothoracic Surgery, Indiana Center for Vascular Biology and Medicine, Indiana University Medical Center, Indianapolis, Indiana 46202, USA
    Shock 21:170-4. 2004
    ..We conclude that p38 MAPK is involved in endotoxin-induced myocardial contractile dysfunction and myocardial TNF-alpha production; however, p38 MAPK's involvement in IL-1 and IL-6 production may be indirectly mediated by TNF-alpha...
  92. ncbi request reprint Preconditioning: evolution of basic mechanisms to potential therapeutic strategies
    Ben M Tsai
    Section of Cardiothoracic Surgery, Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Shock 21:195-209. 2004
    ....
  93. pmc Insulin-like growth factor-1 in myocardial tissue: interaction with tumor necrosis factor
    Meijing Wang
    Department of Surgery, and Indiana Center for Vascular Biology and Medicine, Indiana University Medical Center, Indianapolis, Indiana, USA
    Crit Care 7:417-9. 2003
    ....
  94. ncbi request reprint Differential effects of phosphodiesterase-5 inhibitors on hypoxic pulmonary vasoconstriction and pulmonary artery cytokine expression
    Ben M Tsai
    Section of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Ann Thorac Surg 81:272-8. 2006
    ....
  95. ncbi request reprint Acute hemodynamic effects of pacing in patients with Fontan physiology: a prospective study
    Brent J Barber
    Department of Pediatric Cardiology, Oregon Health and Science University, Portland, Oregon, USA
    J Am Coll Cardiol 46:1937-42. 2005
    ..The purpose of this research was to assess the hemodynamic response to atrial, ventricular, and dual-chamber pacing in patients with Fontan physiology...
  96. doi request reprint Performance of a 3-bladed propeller pump to provide cavopulmonary assist in the failing Fontan circulation
    Amy L Throckmorton
    Section of Cardiothoracic Surgery, Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Ann Thorac Surg 86:1343-7. 2008
    ..We hypothesized that a propeller pump design would function optimally to provide cavopulmonary assist in a univentricular Fontan circulation...
  97. ncbi request reprint The role of estrogen in cardiovascular disease
    Lauren Baker
    Department of Surgery and Department of Physiology, Indiana Center for Vascular Biology and Medicine, Indiana University Medical Center, Indianapolis, IN 46033, USA
    J Surg Res 115:325-44. 2003
    ....
  98. doi request reprint Ventricular assist device implantation in the pediatric population: does pump size selection and associated hemodynamics impact outcomes?
    S Adil Husain
    Department of Pediatrics, Congenital Heart Center, College of Medicine, University of Florida, Gainesville, Florida, USA
    ASAIO J 54:474-8. 2008
    ..72, VAD rate ratio of 0.72 and fill/empty ratio of 0.78. We report a series of pediatric patients with wide ranging BSA receiving VAD implantation. Selection of appropriate sized blood pumps can be correlated with decreased VADRC...
  99. ncbi request reprint Endothelium-dependent pulmonary artery vasorelaxation is dysfunctional in males but not females after acute lung injury
    Ben M Tsai
    Department of Surgery and Cellular and Integrative Physiology, Indiana University Medical Center, Indianapolis, 46202, USA
    Surgery 138:78-84. 2005
    ..We hypothesized that endothelium-dependent pulmonary vasorelaxation is impaired in males and that this effect is related to differences in local inflammatory cytokine expression from the pulmonary vasculature...
  100. ncbi request reprint Sexual dimorphism in myocardial tumor necrosis factor-alpha and cardiac function during endotoxin tolerance
    Jeffrey M Pitcher
    Department of Surgery, Indiana Center for Vascular Biology and Medicine, Indiana University School of Medicine, Indianapolis, USA
    Surgery 138:223-8. 2005
    ....