House Ear Institute

Summary

Organization: House Ear Institute
Country: USA

Top Publications

  1. pmc BMP signaling is necessary for patterning the sensory and nonsensory regions of the developing mammalian cochlea
    Takahiro Ohyama
    Division of Cell Biology and Genetics, House Ear Institute, Los Angeles, California 90057, USA
    J Neurosci 30:15044-51. 2010
  2. ncbi Chondrosarcoma of the skull base: long-term follow-up
    Derald E Brackmann
    University of Southern California, Los Angeles, California, USA
    Otol Neurotol 27:981-91. 2006
  3. ncbi Distribution of bacterial proteins in biofilms formed by non-typeable Haemophilus influenzae
    Paul Webster
    Ahmanson Advanced Electron Microscopy and Imaging Center, House Ear Institute, Los Angeles, CA 90057, USA
    J Histochem Cytochem 54:829-42. 2006
  4. ncbi Clinical performance of children following revision surgery for a cochlear implant
    Jose N Fayad
    House Ear Institute, 2100 West Third Street, Los Angeles, CA 90058, USA
    Otolaryngol Head Neck Surg 134:379-84. 2006
  5. pmc Synergistic effect of interleukin 1 alpha on nontypeable Haemophilus influenzae-induced up-regulation of human beta-defensin 2 in middle ear epithelial cells
    Sung Kyun Moon
    The Gonda Department of Cell and Molecular Biology, House Ear Institute, Los Angeles, CA, USA
    BMC Infect Dis 6:12. 2006
  6. ncbi Effects of aspirin on distortion product otoacoustic emission suppression in human adults: a comparison with neonatal data
    Carolina Abdala
    House Ear Institute, 2100 West Third Street, Children s Auditory Research and Evaluation Center, Los Angeles, California 90057, USA
    J Acoust Soc Am 118:1566-75. 2005
  7. ncbi Intratympanic steroid injection for treatment of idiopathic sudden hearing loss
    William H Slattery
    House Ear Institute, House Ear Clinic, Los Angeles, California 90057, USA
    Otolaryngol Head Neck Surg 133:251-9. 2005
  8. ncbi Paget disease and sensorineural hearing loss associated with spiral ligament degeneration
    Karen Borne Teufert
    Histopathology Department, House Ear Institute, Los Angeles, California 90057, USA
    Otol Neurotol 26:387-91; discussion 391. 2005
  9. ncbi Eya1 acts upstream of Tbx1, Neurogenin 1, NeuroD and the neurotrophins BDNF and NT-3 during inner ear development
    Rick A Friedman
    Gonda Department of Cell and Molecular Biology, House Ear Institute, 2100 W Third Street, Los Angeles, CA 90057, USA
    Mech Dev 122:625-34. 2005
  10. ncbi Loudness growth in cochlear implants: effect of stimulation rate and electrode configuration
    Qian Jie Fu
    Department of Auditory Implants and Perception, House Ear Institute, Los Angeles, CA 90057, USA
    Hear Res 202:55-62. 2005

Research Grants

Detail Information

Publications62

  1. pmc BMP signaling is necessary for patterning the sensory and nonsensory regions of the developing mammalian cochlea
    Takahiro Ohyama
    Division of Cell Biology and Genetics, House Ear Institute, Los Angeles, California 90057, USA
    J Neurosci 30:15044-51. 2010
    ..Our results suggest BMP signaling is required for patterning sensory and nonsensory tissue in the mammalian cochlea...
  2. ncbi Chondrosarcoma of the skull base: long-term follow-up
    Derald E Brackmann
    University of Southern California, Los Angeles, California, USA
    Otol Neurotol 27:981-91. 2006
    ..We describe the use of lateral skull base techniques for these lesions and examine the long-term outcomes. The pathological features, radiological findings, and radiotherapy options are also discussed...
  3. ncbi Distribution of bacterial proteins in biofilms formed by non-typeable Haemophilus influenzae
    Paul Webster
    Ahmanson Advanced Electron Microscopy and Imaging Center, House Ear Institute, Los Angeles, CA 90057, USA
    J Histochem Cytochem 54:829-42. 2006
    ....
  4. ncbi Clinical performance of children following revision surgery for a cochlear implant
    Jose N Fayad
    House Ear Institute, 2100 West Third Street, Los Angeles, CA 90058, USA
    Otolaryngol Head Neck Surg 134:379-84. 2006
    ..The purpose of this study was to describe the causes for revision surgery and to compare clinical performance before and after surgery in children who required electrode reinsertion...
  5. pmc Synergistic effect of interleukin 1 alpha on nontypeable Haemophilus influenzae-induced up-regulation of human beta-defensin 2 in middle ear epithelial cells
    Sung Kyun Moon
    The Gonda Department of Cell and Molecular Biology, House Ear Institute, Los Angeles, CA, USA
    BMC Infect Dis 6:12. 2006
    ....
  6. ncbi Effects of aspirin on distortion product otoacoustic emission suppression in human adults: a comparison with neonatal data
    Carolina Abdala
    House Ear Institute, 2100 West Third Street, Children s Auditory Research and Evaluation Center, Los Angeles, California 90057, USA
    J Acoust Soc Am 118:1566-75. 2005
    ..This finding does not support the hypothesis that non-adultlike DPOAE suppression characterizing newborns can be explained by minor impairments or alterations of OHC function...
  7. ncbi Intratympanic steroid injection for treatment of idiopathic sudden hearing loss
    William H Slattery
    House Ear Institute, House Ear Clinic, Los Angeles, California 90057, USA
    Otolaryngol Head Neck Surg 133:251-9. 2005
    ..To conduct a clinical trial of intratympanic steroid injection for idiopathic sudden sensorineural hearing loss in subjects who failed oral steroid therapy...
  8. ncbi Paget disease and sensorineural hearing loss associated with spiral ligament degeneration
    Karen Borne Teufert
    Histopathology Department, House Ear Institute, Los Angeles, California 90057, USA
    Otol Neurotol 26:387-91; discussion 391. 2005
    ..Previously unreported cystic degeneration of the spiral ligament in cases of Paget disease...
  9. ncbi Eya1 acts upstream of Tbx1, Neurogenin 1, NeuroD and the neurotrophins BDNF and NT-3 during inner ear development
    Rick A Friedman
    Gonda Department of Cell and Molecular Biology, House Ear Institute, 2100 W Third Street, Los Angeles, CA 90057, USA
    Mech Dev 122:625-34. 2005
    ..We discuss a potential mechanism for the absence of neural precursors in the Eya1-/- inner ears and the primary and secondary mechanisms for the loss of cochleovestibular ganglion cells in the Eya1bor/bor hypomorphic mutant...
  10. ncbi Loudness growth in cochlear implants: effect of stimulation rate and electrode configuration
    Qian Jie Fu
    Department of Auditory Implants and Perception, House Ear Institute, Los Angeles, CA 90057, USA
    Hear Res 202:55-62. 2005
    ....
  11. pmc Across- and within-channel envelope interactions in cochlear implant listeners
    Monita Chatterjee
    Department of Auditory Implants and Perception, House Ear Institute, Los Angeles, CA 90057, USA
    J Assoc Res Otolaryngol 5:360-75. 2004
    ..These results suggest that, as has been shown in acoustic stimulation, central, across-channel temporal processing mechanisms also occur in electrical stimulation...
  12. ncbi Oral steroid regimens for idiopathic sudden sensorineural hearing loss
    William H Slattery
    House Ear Institute, Los Angeles, CA 90057, USA
    Otolaryngol Head Neck Surg 132:5-10. 2005
    ..To determine hearing recovery in patients with idiopathic sudden hearing loss treated with varying amounts of oral steroids...
  13. ncbi Frequency-place compression and expansion in cochlear implant listeners
    Deniz Baskent
    Department of Biomedical Engineering, University of Southern California, Los Angeles, California 90089, USA
    J Acoust Soc Am 116:3130-40. 2004
    ..The present study shows that frequency-place mapping is an important factor in implant performance and an individual implant patient's map could be optimized with functional tests using frequency-place manipulations...
  14. ncbi Randomized double-blinded, placebo-controlled clinical trial of famciclovir for reduction of Ménière's disease symptoms
    M Jennifer Derebery
    House Ear Institute, Los Angeles, California 90057, USA
    Otolaryngol Head Neck Surg 131:877-84. 2004
    ..To conduct a clinical trial of famciclovir for symptom control in Meniere's disease...
  15. ncbi Distribution of low-frequency nerve fibers in the auditory nerve: Temporal bone findings and clinical implications
    Jose N Fayad
    Department of Histopathology, Temporal Bone Laboratory, House Ear Institute, Los Angeles, California 90057, USA
    Otol Neurotol 27:1074-7. 2006
    ..Low-frequency cochlear fibers are on the outer surface of the auditory nerve adjacent to the vestibular nerve in the distal part of the internal auditory canal...
  16. ncbi Recognition of simulated telephone speech by cochlear implant users
    Qian Jie Fu
    House Ear Institute, 2100 West Third Street, Los Angeles, CA 90057, USA
    Am J Audiol 15:127-32. 2006
    ..To evaluate cochlear implant users' understanding of telephone speech...
  17. ncbi Prevention and treatment of cerebrospinal fluid leak after translabyrinthine acoustic tumor removal
    Jose N Fayad
    House Clinic and House Ear Institute, Los Angeles, California 90057, USA
    Otol Neurotol 28:387-90. 2007
    ..To determine the incidence rate of cerebrospinal fluid (CSF) leak after translabyrinthine acoustic tumor removal using titanium mesh cranioplasty and to compare with previous series and historical controls...
  18. doi Bone-anchored hearing aid subjective benefit for unilateral deafness
    John W House
    House Clinic, Los Angeles, California 90057, USA
    Laryngoscope 120:601-7. 2010
    ..Determine the benefit of the bone-anchored hearing aid (BAHA) in patients with unilateral deafness...
  19. doi Jugular foramen tumors: clinical characteristics and treatment outcomes
    Jose N Fayad
    House Ear Institute and House Ear Clinic, Los Angeles, California 90057, USA
    Otol Neurotol 31:299-305. 2010
    ..To describe the diagnosis, management, and treatment outcome of jugular foramen (JF) tumors...
  20. doi Microsurgery after radiosurgery or radiotherapy for vestibular schwannomas
    William H Slattery
    Clinical Studies, House Ear Institute, House Ear Clinic, University of Southern California, 2100 West Third Street, Los Angeles, CA 90057, USA
    Otolaryngol Clin North Am 42:707-15. 2009
    ..It is recommended that patients who require microsurgical excision following radiosurgery or radiotherapy have a more conservative approach compared to non-irradiated cases...
  21. pmc Melodic contour identification and music perception by cochlear implant users
    John J Galvin
    Department of Communication and Auditory Neuroscience, House Ear Institute, Los Angeles, California 90057, USA
    Ann N Y Acad Sci 1169:518-33. 2009
    ..With fixed constraints on spectral resolution, such as occurs with hearing loss or an auditory prosthesis, training and experience can provide considerable improvements in music perception and appreciation...
  22. pmc Histopathologic assessment of fibrosis and new bone formation in implanted human temporal bones using 3D reconstruction
    Jose N Fayad
    Department of Histopathology, House Ear Institute, Los Angeles, CA 90057, USA
    Otolaryngol Head Neck Surg 141:247-52. 2009
    ..To evaluate new bone formation and fibrosis in implanted human temporal bones and relate that to neurosensory elements preservation...
  23. pmc Effect of a competing instrument on melodic contour identification by cochlear implant users
    John J Galvin
    Department of Communication and Auditory Neuroscience, House Ear Institute, Los Angeles, California 90057, USA
    J Acoust Soc Am 125:EL98-103. 2009
    ..However, the most musically experienced CI users were able to make use of timbre and F0 differences between instruments...
  24. pmc Changes in the DP-gram during the preterm and early postnatal period
    Carolina Abdala
    House Ear Institute, 2100 West Third Street, Children s Auditory Research and Evaluation Center, Los Angeles, California 90057, USA
    Ear Hear 29:512-23. 2008
    ..This information provides normative guidelines for audiologists or hearing screeners using DPOAEs to monitor infant hearing status...
  25. pmc Assessing speech pattern contrast perception in infants: early results on VRASPAC
    Amy Martinez
    House Ear Institute, Children s Auditory Research and Evaluation Center, Los Angeles, California 90057, U S A
    Otol Neurotol 29:183-8. 2008
    ..To assess perception of specific speech pattern contrasts in infants with normal hearing (NH) and infants with sensorineural hearing loss (HL)...
  26. pmc Perceptual learning and auditory training in cochlear implant recipients
    Qian Jie Fu
    Department of Auditory Implants and Perception, House Ear Institute, Los Angeles, California 90057, USA
    Trends Amplif 11:193-205. 2007
    ..Provided with an inexpensive and effective auditory training program, CI recipients may find the motivation and momentum to get the most from the implant device...
  27. ncbi Facial palsy and fallopian canal expansion associated with idiopathic intracranial hypertension
    Derald E Brackmann
    House Clinic and House Ear Institute, Los Angeles 90057, and University of California, San Diego, Division of Otolaryngology Head and Neck Surgery, La Jolla, California, USA
    Otol Neurotol 28:715-8. 2007
    ..Describe neurotologic findings associated with idiopathic intracranial hypertension (IIH)...
  28. pmc Assessing auditory capabilities in young children
    Laurie S Eisenberg
    House Ear Institute, 2100 W Third Street, Los Angeles, CA 90057, USA
    Int J Pediatr Otorhinolaryngol 71:1339-50. 2007
    ..This battery is part of a clinical research protocol designed to track auditory development in this population...
  29. pmc Melodic contour identification by cochlear implant listeners
    John J Galvin
    Department of Auditory Implants and Perception, House Ear Institute, Los Angeles, California 90057, USA
    Ear Hear 28:302-19. 2007
    ..The present study also compared MCI performance with familiar melody identification (FMI) performance, with and without MCI training...
  30. ncbi Hearing preservation surgery for neurofibromatosis Type 2-related vestibular schwannoma in pediatric patients
    William H Slattery
    House Ear Clinic, House Ear Institute, Los Angeles, California 90057, USA
    J Neurosurg 106:255-60. 2007
    ..The authors reviewed the proportion of pediatric patients with neurofibromatosis Type 2 (NF2) in whom hearing was preserved after middle fossa resection of vestibular schwannoma (VS)...
  31. ncbi Hearing changes after diagnosis in neurofibromatosis type 2
    Ann Masuda
    Clinical Studies Department, House Ear Institute, Los Angeles, California 90057, USA
    Otol Neurotol 25:150-4. 2004
    ..Describe the changes in hearing ability and progression of disease over time in subjects with neurofibromatosis Type 2 enrolled in a multicenter natural history study of vestibular schwannomas in neurofibromatosis Type 2...
  32. ncbi Allergy and the contemporary otologist
    M Jennifer Derebery
    House Ear Clinic, 2100 West Third Street, Los Angeles, CA 90057, USA
    Otolaryngol Clin North Am 36:989-1008. 2003
    ..Patients with significant and chronic symptoms, including those with labyrinthine symptoms of allergy, respond well to specific immunotherapy or dietary elimination...
  33. ncbi Maturation of human central auditory system activity: evidence from multi-channel evoked potentials
    C W Ponton
    Electrophysiology Laboratory, House Ear Institute, Los Angeles, CA 90057, USA
    Clin Neurophysiol 111:220-36. 2000
    ..The purpose of this study was to evaluate central auditory system maturation based on detailed data from multi-electrode recordings of long-latency auditory evoked potentials (AEPs)...
  34. ncbi Endogenously generated spontaneous spiking activities recorded from postnatal spiral ganglion neurons in vitro
    X Lin
    Section on Neurobiology, Department of Cell and Molecular Biology, House Ear Institute, 2100 W 3rd St, Los Angeles, CA 90057, USA
    Brain Res Dev Brain Res 119:297-305. 2000
    ..Intracellular mechanisms for generating the spontaneous random spikes and the possible roles of such spontaneous activities in the postnatal development of SG neurons are discussed...
  35. ncbi Effect of stimulation rate on phoneme recognition by nucleus-22 cochlear implant listeners
    Q J Fu
    Department of Auditory Implants and Perception, House Ear Institute, Los Angeles, California 90057, USA
    J Acoust Soc Am 107:589-97. 2000
    ..The pattern of results for both electrical and acoustic hearing is consistent with a simple model of temporal integration with an equivalent rectangular duration (ERD) of the temporal integrator of about 7 ms...
  36. ncbi The human olivocochlear system: organization and development
    J K Moore
    Department of Neuroanatomy, House Ear Institute, Los Angeles, CA 90057, USA
    Audiol Neurootol 4:311-25. 1999
    ..With increasing age, the dorsal cluster of small cells shifts from its original cap-like position over the lateral olivary nucleus to become an extended column of cells lying among the fibers of the olivocochlear bundle...
  37. ncbi Speech recognition with altered spectral distribution of envelope cues
    R V Shannon
    House Ear Institute, Los Angeles, California 90057, USA
    J Acoust Soc Am 104:2467-76. 1998
    ..Overall, these results show that, for four bands, the frequency alignment of the analysis bands and carrier bands is critical for good performance, while the exact frequency divisions and overlap in carrier bands are not as critical...
  38. ncbi Spatial mislocalization of EEG electrodes -- effects on accuracy of dipole estimation
    D Khosla
    Electrophysiology Department, House Ear Institute, Los Angeles, CA 90057, USA
    Clin Neurophysiol 110:261-71. 1999
    ..It is expected that spatial mislocalization of electrodes will introduce errors in this estimation. The present study uses simulated and real data to quantify these errors for dipole current sources in a spherical head model...
  39. ncbi Temporal mechanisms underlying recovery from forward masking in multielectrode-implant listeners
    M Chatterjee
    Department of Auditory Implants and Perception, House Ear Institute, Los Angeles, California 90057, USA
    J Acoust Soc Am 105:1853-63. 1999
    ..Nonmonotonicities sometimes observed in the recovery functions may be accounted for by considering the influence of neural adaptation...
  40. ncbi Effects of stimulation mode on threshold and loudness growth in multielectrode cochlear implants
    M Chatterjee
    Department of Auditory Implants and Perception, House Ear Institute, Los Angeles, California 90057, USA
    J Acoust Soc Am 105:850-60. 1999
    ..Thus, dynamic range and the shape of loudness growth can be directly linked to the spatial separation between active and return electrodes...
  41. ncbi Gender distinctions and lateral asymmetry in the low-level auditory brainstem response of the human neonate
    Y S Sininger
    Children s Auditory Research and Evaluation Center, House Ear Institute, Los Angeles, CA 91401, USA
    Hear Res 126:58-66. 1998
    ..The argument is made that superior right ear performance may be part of cerebral laterality in auditory function...
  42. ncbi Effects of amplitude nonlinearity on phoneme recognition by cochlear implant users and normal-hearing listeners
    Q J Fu
    Department of Auditory Implants and Perception, House Ear Institute, Los Angeles, California 90057, USA
    J Acoust Soc Am 104:2570-7. 1998
    ..The function relating amplitude mapping exponent and performance was relatively flat, indicating that phoneme recognition was only mildly affected by amplitude nonlinearity...
  43. ncbi Importance of tonal envelope cues in Chinese speech recognition
    Q J Fu
    Department of Auditory Implants and Perception, House Ear Institute, Los Angeles, California 90057, USA
    J Acoust Soc Am 104:505-10. 1998
    ..The quantitative role of tones in Chinese speech recognition was further explored using a power-function model and found to play a significant role in relating phoneme recognition to sentence recognition...
  44. ncbi Interactions of forward and simultaneous masking in intensity discrimination
    F G Zeng
    Department of Auditory Implants and Perception, House Ear Institute, Los Angeles, California 90057, USA
    J Acoust Soc Am 103:2021-30. 1998
    ..Both peripheral and central mechanisms may have contributed to the occurrence, reduction and enhancement of the midlevel hump under these masking conditions...
  45. ncbi Substrate for rapid feedforward inhibition of the auditory forebrain
    R L Saint Marie
    Neuroanatomy Department, House Ear Institute, Los Angeles, CA 90057, USA
    Brain Res 765:173-6. 1997
    ..We propose that, based on their large size, GABAergic tectothalamic axons provide a substrate for rapid feedforward inhibition of geniculate neurons...
  46. ncbi Speech perception without hearing
    L E Bernstein
    Department of Communication Neuroscience, House Ear Institute, Los Angeles, California 90057, USA
    Percept Psychophys 62:233-52. 2000
    ..The results suggest that the necessity to perceive speech without hearing can be associated with enhanced visual phonetic perception in some individuals...
  47. ncbi Speech recognition with reduced spectral cues as a function of age
    L S Eisenberg
    House Ear Institute, Los Angeles, California 90057, USA
    J Acoust Soc Am 107:2704-10. 2000
    ..These findings have implications for the application of auditory sensory devices for young children with early-onset hearing loss...
  48. ncbi Competence, specification and commitment in otic placode induction
    A K Groves
    Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA
    Development 127:3489-99. 2000
    ..Use of the four molecular otic placode markers suggests that induction of the otic placode in birds occurs earlier than previously thought, and proceeds in a series of steps that are independently regulated...
  49. ncbi Ipsilateral distortion product otoacoustic emission (2f1-f2) suppression in children with sensorineural hearing loss
    Carolina Abdala
    Children s Auditory Research and Evaluation Center, House Ear Institute, 2100 West Third Street, Los Angeles, California 90057, USA
    J Acoust Soc Am 114:919-31. 2003
    ..The unique patterns of atypical DPOAE suppression in subjects with similar audiograms may suggest different patterns of underlying sensory cell damage. This speculation warrants further investigation...
  50. ncbi Congenital aural atresia surgery: long-term results
    Antonio De la Cruz
    House Ear Clinic, University of Southern California School of Medicine, USA
    Otolaryngol Head Neck Surg 129:121-7. 2003
    ..We also reviewed complications such as external auditory canal stenosis, lateralization and perforation of the tympanic membrane, sensorineural hearing loss, and facial palsy...
  51. ncbi Optical recordings of Ca2+ signaling activities from identified inner ear cells in cochlear slices and hemicochleae
    Xi Lin
    Section on Neurobiology, Leslie and Susan Gonda Department of Cell and Molecular Biology, 2100 West Third Street, House Ear Institute, Los Angeles, CA 90057, USA
    Brain Res Brain Res Protoc 11:92-100. 2003
    ....
  52. ncbi The relative importance of amplitude, temporal, and spectral cues for cochlear implant processor design
    Robert V Shannon
    Department of Auditory Implants and Perception, House Ear Institute, Los Angeles, CA 90057, USA
    Am J Audiol 11:124-7. 2002
    ..If there is a shift or distortion of 2 to 3 mm between frequency and cochlear place, speech recognition is decreased dramatically...
  53. pmc Holes in hearing
    Robert V Shannon
    House Ear Institute, Los Angeles, CA 90057, USA
    J Assoc Res Otolaryngol 3:185-99. 2002
    ..No significant differences were observed among the four conditions that redistributed the spectral information around the hole, suggesting that rerouting spectral information around a hole was no better than simply dropping it...
  54. ncbi Developmental variation, homology, and the pharyngula stage
    A Collazo
    House Ear Institute, 2100 West Third St, Los Angeles, California 90057, USA
    Syst Biol 49:3-18. 2000
    ..Understanding the genetic basis of lateral line development would help not only in hypothesizing possible transformational series but also in determining how many genes may have been required for these transformations...
  55. ncbi Tuberculous otitis media
    Fred H Linthicum Jr
    House Ear Institute, Los Angeles, California, USA
    Otol Neurotol 23:235-6. 2002
  56. pmc Cytoarchitectural and axonal maturation in human auditory cortex
    J K Moore
    Department of Neuroanatomy, House Ear Institute, Los Angeles, CA 90057, USA
    J Assoc Res Otolaryngol 2:297-311. 2001
    ..This extended time span of axonal maturation has implications for the emergence of auditory cortical function...
  57. ncbi DPOAE suppression tuning: cochlear immaturity in premature neonates or auditory aging in normal-hearing adults?
    C Abdala
    House Ear Institute, Children s Auditory Research and Evaluation Center, Los Angeles, California 90057, USA
    J Acoust Soc Am 110:3155-62. 2001
    ..However, nonadultlike suppression growth observed in children at 6000 Hz warrants further attention and may be indicative of subtle alternations in the adult cochlea at high frequencies...
  58. ncbi Enhanced speechreading in deaf adults: can short-term training/practice close the gap for hearing adults?
    L E Bernstein
    Center for Auditory and Speech Sciences, Gallaudet University, Washington, DC, USA
    J Speech Lang Hear Res 44:5-18. 2001
    ....
  59. ncbi Recognition of time-distorted sentences by normal-hearing and cochlear-implant listeners
    Q J Fu
    Department of Auditory Implants and Perception, House Ear Institute, Los Angeles, California 90057, USA
    J Acoust Soc Am 109:379-84. 2001
    ..Some CI listeners have more difficulty with time-compressed speech, as produced by rapid speakers, because of reduced spectral resolution and deficits in auditory temporal processing...
  60. ncbi Organization of the human superior olivary complex
    J K Moore
    Department of Neuroanatomy, House Ear Institute, Los Angeles, California 90057, USA
    Microsc Res Tech 51:403-12. 2000
    ....
  61. ncbi The task dependence of staged versus cascaded processing: an empirical and computational study of Stroop interference in speech production
    C T Kello
    Department of Psychology, Carnegie Mellon University, USA
    J Exp Psychol Gen 129:340-60. 2000
    ..Results are discussed in relation to mechanisms of strategic control and the link between cognition and action...
  62. ncbi Action potentials and underlying voltage-dependent currents studied in cultured spiral ganglion neurons of the postnatal gerbil
    X Lin
    Auditory Physiology Laboratory The Hugh Knowles Center, Northwestern University, Evanston, IL 60208, USA
    Hear Res 108:157-79. 1997
    ..Possible roles of spontaneous APs in the development of the cochlea and the role of voltage-gated currents in the function of SG neurons under normal and pathological conditions are discussed...

Research Grants62

  1. Audio Processing for Cochlear Implants
    Qian Jie Fu; Fiscal Year: 2007
    ..It is also of great theoretical interest in terms of understanding the neural and perceptual mechanisms involved in pattern recognition. ..
  2. Effects of Training on Adult Cochlear Implant Users
    Qian Jie Fu; Fiscal Year: 2009
    ..As recent advances in implant technology seem to be reaching the point of diminishing returns, auditory training may provide the most cost-effective approach for cochlear implant patients to maximize the benefit of the implant device. ..
  3. Audio Processing for Cochlear Implants
    Qian Jie Fu; Fiscal Year: 2009
    ..It is also of great theoretical interest in terms of understanding the neural and perceptual mechanisms involved in pattern recognition. ..
  4. Effects of Training on Adult Cochlear Implant Users
    Qian Jie Fu; Fiscal Year: 2005
    ..Theoretically, these results will increase our understanding of central auditory system plasticity and the cortical processes and mechanisms involved in perceptual learning. ..
  5. SPEECH PATTERN RECOGNITION IN ELECTRIC HEARING
    Qian Jie Fu; Fiscal Year: 2005
    ..abstract_text> ..
  6. Effects of Training on Adult Cochlear Implant Users
    Qian Jie Fu; Fiscal Year: 2007
    ..As recent advances in implant technology seem to be reaching the point of diminishing returns, auditory training may provide the most cost-effective approach for cochlear implant patients to maximize the benefit of the implant device. ..
  7. Audio Processing for Cochlear Implants
    Qian Jie Fu; Fiscal Year: 2010
    ..It is also of great theoretical interest in terms of understanding the neural and perceptual mechanisms involved in pattern recognition. ..
  8. Effects of Training on Adult Cochlear Implant Users
    Qian Jie Fu; Fiscal Year: 2010
    ..As recent advances in implant technology seem to be reaching the point of diminishing returns, auditory training may provide the most cost-effective approach for cochlear implant patients to maximize the benefit of the implant device. ..
  9. Audio Processing for Cochlear Implants
    Qian Jie Fu; Fiscal Year: 2009
    ..It is also of great theoretical interest in terms of understanding the neural and perceptual mechanisms involved in pattern recognition. ..
  10. Effects of Training on Adult Cochlear Implant Users
    Qian Jie Fu; Fiscal Year: 2009
    ..As recent advances in implant technology seem to be reaching the point of diminishing returns, auditory training may provide the most cost-effective approach for cochlear implant patients to maximize the benefit of the implant device. ..
  11. Postnatal Cochlear Maturation and Sources of Immaturity
    Carolina Abdala; Fiscal Year: 2005
    ..Correlations between variance in energy reflectance and variance in DPOAE suppression and amplitude will be examined to elucidate the contribution of an immature middle ear system to immaturities in DPOAE suppression. ..
  12. Peripheral Auditory System Function in Humans: Continuum of Maturation and Aging
    Carolina Abdala; Fiscal Year: 2010
    ....
  13. Peripheral Auditory System Function in Humans: Continuum of Maturation and Aging
    Carolina Abdala; Fiscal Year: 2009
    ....
  14. Development and Adaptive Behavior of Young Children with Hearing Loss
    Carren Stika; Fiscal Year: 2010
    ..The knowledge gained from this longitudinal investigation will inform developmental theory and should promote effective and responsive child and parent support interventions for young children with mild-to-severe hearing loss. ..
  15. Development and Adaptive Behavior of Young Children with Hearing Loss
    Laurie Eisenberg; Fiscal Year: 2009
    ..The knowledge gained from this longitudinal investigation will inform developmental theory and should promote effective and responsive child and parent support interventions for young children with mild-to-severe hearing loss. ..
  16. Assessing Auditory Capacity in Hearing-Impaired Children
    Laurie Eisenberg; Fiscal Year: 2007
    ..The results will be analyzed to explain and model auditory perceptual development in terms of multiple contributing variables and their interactions. ..
  17. Development and Adaptive Behavior of Young Children with Hearing Loss
    Laurie Eisenberg; Fiscal Year: 2009
    ..The knowledge gained from this longitudinal investigation will inform developmental theory and should promote effective and responsive child and parent support interventions for young children with mild-to-severe hearing loss. ..
  18. Study of a genetic network involved in ear development
    Rick Friedman; Fiscal Year: 2005
    ..These and future experiments represent the natural progression from my Mentored Clinical Scientist Development Award (K08). ..
  19. Genetic Analysis of Age Related Hearing Impairment
    Rick Friedman; Fiscal Year: 2009
    ..Each of the centers brings unique strengths and capabilities. The investigators from the House Ear Institute and the University of Antwerp have expertise in the genetics of hearing loss, GWAS and surgical access to ..
  20. Genetic Analysis of Age Related Hearing Impairment
    Rick A Friedman; Fiscal Year: 2010
    ..Each of the centers brings unique strengths and capabilities. The investigators from the House Ear Institute and the University of Antwerp have expertise in the genetics of hearing loss, GWAS and surgical access to ..
  21. Sustained Release Inner Ear Delivery of Corticosteroid
    William Slattery; Fiscal Year: 2007
    ..This system could also be used for other drugs where chronic delivery is essential. ..
  22. Enhancing Tone Recognition for Cochlear Implant Users
    Xin Luo; Fiscal Year: 2007
    ..Device implementation and applications of mixed stimulation modes for tonal language speech processing in cochlear implants will be investigated. ..
  23. Cell and Molecular Analysis of Human Temporal Bones
    Fred Linthicum; Fiscal Year: 2007
    ..Specific Aim 6: To encourage collaborations with investigators who have little experience using human temporal bones. Specific Aim 7: To encourage participation of young scientists in temporal bone research. ..
  24. AUDIOVISUAL SPEECH PROCESSING
    LYNNE BERNSTEIN; Fiscal Year: 2004
    ..Accurate knowledge about the speech perceiving brain is needed for all clinical applications involving speech communication. ..
  25. Visual Speech Perception and Neural Processing
    LYNNE BERNSTEIN; Fiscal Year: 2007
    ..Knowledge about learning and plasticity in adults is important, as hearing loss is a frequent occurrence associated with aging. ..
  26. Visual Speech Perception and Neural Processing
    LYNNE BERNSTEIN; Fiscal Year: 2007
    ..Our visual speech synthesizer will be useful for training deaf children in vocabulary development and lipreading. ..
  27. Multidisciplinary Approaches to Patient-Oriented Studies of Auditory Neuropathy
    LYNNE BERNSTEIN; Fiscal Year: 2007
    ..Important opportunities are lost when the clinical and research enterprises become too distinct from each other, and we will undertake to develop mechanisms that promote full partnership between the lab and the clinic. ..
  28. Structural Basis of Outer Hair Cell Function
    Federico Kalinec; Fiscal Year: 2010
    ....
  29. Electric Stimulation of the Human Cochlea, Brainstem, and Midbrain
    Robert Shannon; Fiscal Year: 2009
    ..In addition, comparison of speech recognition and profiles of psychophysical performance will suggest links between basic perceptual capabilities and more complex auditory pattern recognition. ..